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  1. Article ; Online: Behandlung im Alter - wann sind Therapiezielwechsel sinnvoll?

    Wappler, Manfred

    MMW Fortschritte der Medizin

    2021  Volume 163, Issue 6, Page(s) 53–55

    Title translation Situations in which we have to change the therapy goal in old patients.
    MeSH term(s) Goals ; Humans ; Motivation
    Language German
    Publishing date 2021-03-30
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1478211-x
    ISSN 1613-3560 ; 1438-3276
    ISSN (online) 1613-3560
    ISSN 1438-3276
    DOI 10.1007/s15006-021-9695-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    Zs.MG 72: Show issues

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  2. Book ; Online ; Thesis: Atemkondensat - ein standardisierbares Messverfahren?

    Wappler, Sandra [Verfasser]

    Vergleichende Untersuchungen zur Atemkondensatgewinnung mittels zweier unterschiedlicher Sammelsysteme

    2023  

    Author's details Sandra Wappler
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek Leipzig
    Publishing place Leipzig
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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    Inter-library loan at ZB MED

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  3. Article: Editorial. "Ein Blick zurück nach vorn"

    Wappler, F.

    Anästhesiologie & Intensivmedizin

    2022  Volume 63, Issue Dez, Page(s) 486

    Language German
    Document type Article
    ZDB-ID 134392-0
    ISSN 0170-5334
    Database Current Contents Medicine

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    Zs.B 1017: Show issues Location:
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  4. Article: Editorial. Grußwort des DGAI-Präsidenten

    Wappler, F.

    Anästhesiologie & Intensivmedizin

    2022  Volume 63, Issue Jan, Page(s) 3

    Language German
    Document type Article
    ZDB-ID 134392-0
    ISSN 0170-5334
    Database Current Contents Medicine

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  5. Article: Plant-insect interactions patterns in three European paleoforests of the late-Neogene—early-Quaternary

    Adroit, Benjamin / Girard, Vincent / Wappler, Torsten

    PeerJ, 6:e5075

    2018  

    Abstract: Plants and insects are constantly interacting in complex ways through forest communities since hundreds of millions of years. Those interactions are often related to variations in the climate. Climate change, due to human activities, may have disturbed ... ...

    Institution Senckenberg Naturhistorische Sammlungen Dresden
    Abstract Plants and insects are constantly interacting in complex ways through forest communities since hundreds of millions of years. Those interactions are often related to variations in the climate. Climate change, due to human activities, may have disturbed these relationships in modern ecosystems. Fossil leaf assemblages are thus good opportunities to survey responses of plant–insect interactions to climate variations over the time. The goal of this study is to discuss the possible causes of the differences of plant–insect interactions’ patterns in European paleoforests from the Neogene–Quaternary transition. This was accomplished through three fossil leaf assemblages: Willershausen, Berga (both from the late Neogene of Germany) and Bernasso (from the early Quaternary of France). In Willershausen it has been measured that half of the leaves presented insect interactions, 35% of the fossil leaves were impacted by insects in Bernasso and only 25% in Berga. The largest proportion of these interactions in Bernasso were categorized as specialist (mainly due to galling) while in Willershausen and Berga those ones were significantly more generalist. Contrary to previous studies, this study did not support the hypothesis that the mean annual precipitation and temperature were the main factors that impacted the different plant–insect interactions’ patterns. However, for the first time, our results tend to support that the hydric seasonality and the mean temperature of the coolest months could be potential factors influencing fossil plant–insect interactions.
    Keywords Berga ; Bernasso ; Ecology ; Ecosystem Science ; Herbivory ; Insect feeding ; Seasonality ; Paleoclimate ; Paleontology ; Plant Science ; Plant-insect associations ; Pleistocene ; Pliocene ; Willershausen Lagerstätte
    Language English
    Document type Article
    Database Repository for Life Sciences

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  6. Article ; Online: Anesthesia for Morbidly Obese Patients.

    Hardt, Katharina / Wappler, Frank

    Deutsches Arzteblatt international

    2023  Volume 120, Issue 46, Page(s) 779–785

    Abstract: Background: The prevalence of morbid obesity (BMI >35 kg/m2) has risen steadily in recent decades. With the corresponding rise in the number of bariatric operations, anesthesiologists deal with this patient group more commonly than before, particularly ... ...

    Abstract Background: The prevalence of morbid obesity (BMI >35 kg/m2) has risen steadily in recent decades. With the corresponding rise in the number of bariatric operations, anesthesiologists deal with this patient group more commonly than before, particularly in specialized centers.
    Methods: This review is based on publications retrieved by a selective search in PubMed, including current guidelines and recommendations issued by specialist societies, as well as expert opinion.
    Results: In the anesthesiological care of morbidly obese patients, a preoperative assessment and risk stratification are just as important as the thoughtful selection of the anesthesia technique, the drugs used and their dosage, and perioperative management. A thorough understanding of the pathophysiological changes and comorbidities of morbid obesity and the associated risks is essential. The risk of pulmonary complications such as respiratory failure, hypoxia, and apnea is markedly higher in morbidly obese patients, especially those with obstructive sleep apnea. Short-acting, less lipophilic anesthetic drugs are particularly useful, as is multimodal pain therapy for the avoidance of high opiate doses. The indication for intensified postoperative monitoring depends on the patient's preexisting illnesses, the type of anesthesia, and the type of surgical procedure. Regional anesthetic techniques should be used if possible.
    Conclusion: The perioperative care of morbidly obese patients presents special challenges. The anesthesiologist must be aware of potential comorbidities, specific risks, and pathophysiological changes in order to provide adequate care to this patient group.
    MeSH term(s) Humans ; Obesity, Morbid/epidemiology ; Obesity, Morbid/surgery ; Obesity, Morbid/complications ; Anesthesia/adverse effects ; Anesthesia/methods ; Hypoxia ; Comorbidity ; Perioperative Care ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology
    Language English
    Publishing date 2023-10-09
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2406159-1
    ISSN 1866-0452 ; 1866-0452
    ISSN (online) 1866-0452
    ISSN 1866-0452
    DOI 10.3238/arztebl.m2023.0216
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Arthropod and Pathogen Damage on Fossil and Modern Plants: Exploring the Origins and Evolution of Herbivory on Land.

    Labandeira, Conrad C / Wappler, Torsten

    Annual review of entomology

    2023  Volume 68, Page(s) 341–361

    Abstract: The use of the functional feeding group-damage type system for analyzing arthropod and pathogen interactions with plants has transformed our understanding of herbivory in fossil plant assemblages by providing data, analyses, and interpretation of the ... ...

    Abstract The use of the functional feeding group-damage type system for analyzing arthropod and pathogen interactions with plants has transformed our understanding of herbivory in fossil plant assemblages by providing data, analyses, and interpretation of the local, regional, and global patterns of a 420-Myr history. The early fossil record can be used to answer major questions about the oldest evidence for herbivory, the early emergence of herbivore associations on land plants, and later expansion on seed plants. The subsequent effects of the Permian-Triassic ecological crisis on herbivore diversity, the resulting formation of biologically diverse herbivore communities on gymnosperms, and major shifts in herbivory ensuing from initial angiosperm diversification are additional issues that need to be addressed. Studies ofherbivory resulting from more recent transient spikes and longer-term climate trends provide important data that are applied to current global change and include herbivore community responses to latitude, altitude, and habitat. Ongoing paleoecological themes remaining to be addressed include the antiquity of modern interactions, differential herbivory between ferns and angiosperms, and origins of modern tropical forests. The expansion of databases that include a multitude of specimens; improvements in sampling strategies; development of new analytical methods; and, importantly, the ability to address conceptually stimulating ecological and evolutionary questions have provided new impetus in this rapidly advancing field.
    MeSH term(s) Animals ; Herbivory/physiology ; Arthropods ; Fossils ; Plants ; Ecosystem
    Language English
    Publishing date 2023-01-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 207927-6
    ISSN 1545-4487 ; 0066-4170
    ISSN (online) 1545-4487
    ISSN 0066-4170
    DOI 10.1146/annurev-ento-120120-102849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Behandlung im Alter - wann sind Therapiezielwechsel sinnvoll?

    Wappler, Manfred

    MMW-Fortschritte der Medizin

    2021  Volume 163, Issue 6, Page(s) 53–55

    Title translation Situations in which we have to change the therapeutic goal in old patients
    Keywords aged ; case studies ; palliative care ; evidence-based medicine
    Subject code AN
    Language German
    Document type Article
    ZDB-ID 2173071-4
    ISSN 1613-3560 ; 1438-3276
    ISSN (online) 1613-3560
    ISSN 1438-3276
    Database Ethics in Medicine (ETHMED)

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  9. Article: Grußwort des DGAl-Präsidenten

    Wappler, F.

    Anästhesiologie & Intensivmedizin

    2021  Volume 62, Issue Jan, Page(s) 3

    Language German
    Document type Article
    ZDB-ID 134392-0
    ISSN 0170-5334
    Database Current Contents Medicine

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  10. Article ; Online: S1-Leitlinie maligne Hyperthermie : Update 2018.

    Wappler, F

    Der Anaesthesist

    2018  Volume 67, Issue 7, Page(s) 529–532

    Abstract: The prevalence of malignant hyperthermia (MH) in Germany is 1:2000-1:3000 and therefore more common than previously assumed, so that anesthesia personnel will more often be confronted with susceptible patients in the clinical setting. After the initial ... ...

    Title translation S1 guidelines on malignant hyperthermia : Update 2018.
    Abstract The prevalence of malignant hyperthermia (MH) in Germany is 1:2000-1:3000 and therefore more common than previously assumed, so that anesthesia personnel will more often be confronted with susceptible patients in the clinical setting. After the initial treatment with 2.5 mg/kg body weight dantrolene, further therapy using up to 10 mg/body weight dantrolene can be indicated for 24 h. Under these circumstances it is important to have a sufficient amount of water available for injection purposes. For outpatient anesthesia a stockage of dantrolene is not necessary as long as the use of MH trigger substances in general is strictly avoided. The introduction of Ryanodex® (Eagle Pharmaceuticals, Woodcliff Lake, NJ, USA), a preparation of dantrolene with clearly improved pharmacological properties, in the clinical practice has not yet been realized in Germany.
    MeSH term(s) Dantrolene/therapeutic use ; Guidelines as Topic ; Humans ; Malignant Hyperthermia/drug therapy
    Chemical Substances Dantrolene (F64QU97QCR)
    Language German
    Publishing date 2018-06-26
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 260-4
    ISSN 1432-055X ; 0003-2417
    ISSN (online) 1432-055X
    ISSN 0003-2417
    DOI 10.1007/s00101-018-0462-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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