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  1. AU="Waqar Ahmed"
  2. AU="Harper, William A."
  3. AU="Fargo, Keith"
  4. AU=Reed Matthew J
  5. AU="Harris, Hannah L"
  6. AU="Asahi, Hiroko"
  7. AU="Mohamed El Mohadab"
  8. AU="Jamjoom, Maan"
  9. AU="Benjamin K. Harley"
  10. AU="Redpath, Stephanie"
  11. AU="Costa Oliveira, Diogo"
  12. AU="Ibarra-Meneses, Ana Victoria"
  13. AU=Ozgenel Guzin Yesim
  14. AU="Shu-Ying Li"
  15. AU="Umemura, Yutaka"
  16. AU=Eiring A M
  17. AU="Eunhee Ha"
  18. AU="Espíndola, Otávio M"
  19. AU=Shahbazian Heshmatollah
  20. AU="Esmaeel Panahi kokhdan"
  21. AU=Peekhaus N
  22. AU="Ferrari-Toniolo, Simone"
  23. AU="Oleg M. Mikhailenok"

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  1. Artikel ; Online: Novel isatin-triazole based thiosemicarbazones as potential anticancer agents: synthesis, DFT and molecular docking studies.

    Mushtaq, Alia / Asif, Rabbia / Humayun, Waqar Ahmed / Naseer, Muhammad Moazzam

    RSC advances

    2024  Band 14, Heft 20, Seite(n) 14051–14067

    Abstract: Thiosemicarbazones of isatin have been found to exhibit versatile bioactivities. In this study, two distinct types of isatin-triazole hybrids 3a and 3b were ... ...

    Abstract Thiosemicarbazones of isatin have been found to exhibit versatile bioactivities. In this study, two distinct types of isatin-triazole hybrids 3a and 3b were accessed
    Sprache Englisch
    Erscheinungsdatum 2024-04-29
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d4ra01937g
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  2. Artikel ; Online: Biomass carbon stock estimation in lesser Himalayan subtropical broadleaf forests of Kashmir

    Raja Waqar Ahmed Khan / Hamayun Shaheen

    Taiwania, Vol 67, Iss 1, Pp 47-

    2022  Band 54

    Abstract: Carbon stock quantification holds vital significance in evaluating the climate change mitigation potential and carbon management of forest ecosystems. The current study was designed to quantify the biomass carbon stocks in the lesser Himalayan ... ...

    Abstract Carbon stock quantification holds vital significance in evaluating the climate change mitigation potential and carbon management of forest ecosystems. The current study was designed to quantify the biomass carbon stocks in the lesser Himalayan subtropical broadleaf forests of the Kashmir region. Primary data about the structural attributes and species composition of the local forests was collected through quadrat-based sampling followed by the application of allometric equations for the estimation of forest biomass. The biomass carbon stocks were calculated as 135.2 Mg ha-1 ranging from a maximum of 226.64 Mg ha-1 to a minimum of 11.83 Mg ha-1. The tree layer contributed a biomass carbon content of 134.67 Mg ha-1 making up to 99% share in the total forest biomass as compared to the shrub and herb layers with a very low biomass carbon value of 0.37 Mg ha-1 and 0.17 Mg ha-1 respectively. Dalbergia sissoo was recorded as the most dominant tree species with a biomass carbon stock value of 40.70 Mg ha-1 followed by Mallotus philippensis (30.09 Mg ha-1) and Ficus palmata (20.11 Mg ha-1). Principal Component Analysis revealed that the variations in the local carbon stocks were significantly correlated with the distribution pattern of the dominant tree species. Generalized Linear models showed a strong affinity of biomass carbon reserves with the structural attributes of the forest stands. This study generated a standard scientific dataset of the local biomass carbon stocks in the subtropical broadleaf forests with dynamic implications in sustainable forestry and carbon pool management in the region.
    Schlagwörter biomass ; carbon pools ; climate ; himalayas ; kashmir ; redd ; subtropical forest ; vegetation ; Biology (General) ; QH301-705.5
    Thema/Rubrik (Code) 550
    Sprache Englisch
    Erscheinungsdatum 2022-01-01T00:00:00Z
    Verlag National Taiwan University
    Dokumenttyp Artikel ; Online
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  3. Artikel: Biomass and soil carbon stocks in relation to the structure and composition of Chir Pine dominated forests in the lesser Himalayan foothills of Kashmir

    Waqar Ahmed Khan, Raja / Shaheen, Hamayun / Awan, Shahzad Naseer

    Carbon management. 2021 Aug. 10, v. 12, no. 4

    2021  

    Abstract: Quantification of carbon stocks is critical to evaluate the potential of an ecosystem to mitigate the impact of global climate change in the REDD + scenario. Present research project was designed to gauge the sequestered carbon in Chir Pine (Pinus ... ...

    Abstract Quantification of carbon stocks is critical to evaluate the potential of an ecosystem to mitigate the impact of global climate change in the REDD + scenario. Present research project was designed to gauge the sequestered carbon in Chir Pine (Pinus roxburghii) dominated forests in the foothills of the western Himalayan region of Kashmir which constitute a significant regional carbon pool. The study outcomes revealed an average carbon stock value of 94.3 Mg/ha from which 68 Mg/ha was shared by soil organic carbon (SOC); whereas average biomass carbon share was 26.3 Mg/ha. P. roxburghii was the most noteworthy species containing an average carbon stock value of 5.93 Mg/ha followed by Quercus incana (3.59 Mg/ha) and Olea cuspidata (2.26 Mg/ha). Average forest biomass was chronicled as 52.5 Mg/ha from which tree biomass was 49.34 Mg/ha. Shrub and herb biomass contributed 1.95 and 0.53 Mg/ha correspondingly whereas the Leaf litter and deadwood necromass produced an average of 0.67 Mg/ha. Ordination analysis revealed that the forest carbon stocks were significantly influenced by the species composition, structural attributes as well as anthropogenic disturbances. Current study has resulted in generating a standard baseline dataset of the regional carbon stocks with diverse implications for sustainable carbon management in REDD + perspective.
    Schlagwörter Olea europaea subsp. cuspidata ; Pinus roxburghii ; Quercus leucotrichophora ; administrative management ; biomass ; carbon sequestration ; carbon sinks ; climate change ; data collection ; dead wood ; ecosystems ; forests ; necromass ; ordination techniques ; plant litter ; research projects ; shrubs ; soil organic carbon ; species diversity ; trees ; Himalayan region ; India
    Sprache Englisch
    Erscheinungsverlauf 2021-0810
    Umfang p. 429-437.
    Erscheinungsort Taylor & Francis
    Dokumenttyp Artikel
    ZDB-ID 2590249-0
    ISSN 1758-3012 ; 1758-3004
    ISSN (online) 1758-3012
    ISSN 1758-3004
    DOI 10.1080/17583004.2021.1966511
    Datenquelle NAL Katalog (AGRICOLA)

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  4. Artikel ; Online: The Bronchodilator Potential of <em>Astragalus sarcocolla</em>: An<em> in vitro</em> Experiment.

    Siddiqui, Waqar Ahmed / Qayyum, Muniza / Qureshi, Aamina Quddus / Khalid, Momina / Zaffar, Sehrish / Bilal, Rabiea

    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

    2023  Band 34, Heft 1, Seite(n) 58–62

    Abstract: Objective: To evaluate the bronchodilatory mechanism of Astragalus sarcocolla (ASE) extract on tracheal smooth muscles of rabbits.: Study design: In-vitro experimental study. Place and Duration of the Study: The animal house of CMH Lahore Medical ... ...

    Abstract Objective: To evaluate the bronchodilatory mechanism of Astragalus sarcocolla (ASE) extract on tracheal smooth muscles of rabbits.
    Study design: In-vitro experimental study. Place and Duration of the Study: The animal house of CMH Lahore Medical College, Lahore, and Institute of Dentistry, NUMS, from October 2022 to May 2023.
    Methodology: Six rabbits were randomly divided into four groups. After euthanising the rabbit, the trachea was carefully dissected out and stabilised in Kreb's Henseleit solution for 30 minutes and then, stimulated by acetylcholine (Ach) 1µm, under mimicked physiological conditions. Group I served as the control group with tracheal smooth muscles stabilised with 1g tension. In Group II (positive control), tracheal smooth muscles were stimulated by potassium chloride (KCl) (80 mM and 25 mM, respectively) to get maximum tracheal smooth muscle contractions. Later, the tissue was exposed to theophylline with three molar concentrations 0.2, 0.4, 0.6, and 0.8 mM, and cumulative dose response curves were formed. In Group III (ASE group), tracheal smooth muscles were stimulated by KCl (80 mM and 25 mM) and was exposed to increasing concentration of ASE. In group IV, tissue was stimulated by KCl (25 mM) and glibenclamide (3 µM), later exposed to increasing concentration of ASE to confirm the bronchodilatory mechanism. The change in isometric contraction of the tissue was recorded using the force displacement transducer connected to a PowerLab data acquisition system. Concentration response curves were drawn, and median effective concentrations (EC50 values) and percentage inhibition were calculated. Non-linear regression was applied for the analysis of the concentration-response curves.
    Results: ASE inhibited the KCl-induced low potassium (25 mM) contractions (EC50 = 0.38 mg/ml, 95% CI: 0.04 - 0.38, n = 6). It only partially inhibited the high potassium-induced contractions in tracheal smooth muscles. Pretreatment with glibenclamide showed a rightward shift of the dose-response curve. Theophylline and ASE significantly reduced the low K+ induced smooth muscle contractions in comparison to the control group (p <0.001, each).
    Conclusion: Astragalus sarcocolla extract produced bronchodilator effects through the activation of ATP sensitive potassium channels in isolated rabbit trachea.
    Key words: Astragalus sarcocolla, Bronchodilators, ATP-sensitive potassium channels, Effective concentration 50, Concentration response curves.
    Mesh-Begriff(e) Humans ; Animals ; Rabbits ; Bronchodilator Agents/pharmacology ; Theophylline ; Glyburide ; Astragalus Plant ; Potassium ; Plant Extracts/pharmacology
    Chemische Substanzen Bronchodilator Agents ; Theophylline (C137DTR5RG) ; Glyburide (SX6K58TVWC) ; Potassium (RWP5GA015D) ; Plant Extracts
    Sprache Englisch
    Erscheinungsdatum 2023-09-14
    Erscheinungsland Pakistan
    Dokumenttyp Journal Article
    ZDB-ID 2276646-7
    ISSN 1681-7168 ; 1022-386X
    ISSN (online) 1681-7168
    ISSN 1022-386X
    DOI 10.29271/jcpsp.2024.01.58
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  5. Artikel ; Online: Comparison of instrument-assisted soft tissue mobilization and proprioceptive neuromuscular stretching on hamstring flexibility in patients with knee osteoarthritis

    Narmeen Anjum / Raheela Kanwal Sheikh / Aadil Omer / Kinza Anwar / Muhammad Manan Haider Khan / Anam Aftab / Waqar Ahmed Awan

    PeerJ, Vol 11, p e

    2023  Band 16506

    Abstract: Background The association between hamstring tightness and knee osteoarthritis (KOA) is significant because tight hamstrings can put more strain on the knee joint, reduce its range of motion, and cause compensatory movements that worsen the KOA. ... ...

    Abstract Background The association between hamstring tightness and knee osteoarthritis (KOA) is significant because tight hamstrings can put more strain on the knee joint, reduce its range of motion, and cause compensatory movements that worsen the KOA. Objective To compare the effects of instrument-assisted soft tissue mobilization (IASTM) and proprioceptive neuromuscular (PNF) on hamstring flexibility in patients with KOA. Methods Data for the randomized controlled trial (NCT05110326) was collected from n = 60 participants randomly divided into group A received IASTM and group B received PNF stretching. In group A, the therapist made 30 strokes gentle strokes with the tool from the origin to the insertion while holding the plane at a 45-degree angle over the treatment area. In group B, PNF stretching was done with three repetitions and 10 seconds rest between each, after isometric contraction of the hamstring muscle using approximately 50% of their maximum strength, holding it for 8 seconds, and then releasing it. A 30-minute session was given to each patient three times per week and was given for 6 weeks. Outcome measures were the visual analog scale (VAS) for pain intensity, the active knee extension test (AKET) for hamstring flexibility, and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) for the health status of KOA patients. Results The study found a significant interaction (p < 0.001) between interventions and time across several measurements. After 6 weeks, both interventions resulted in significant improvements (p < 0.001) across all dependent variables, with group A (IASTM) showing more significant improvement in hamstring flexibility, pain reduction, and health status (p < 0.001) compared to group B (PNF). Conclusions Both the IASTM technique and PNF stretching resulted in increased hamstring flexibility, decreased pain, and enhanced general health. The IASTM technique, however, showed potential benefits over PNF stretching in terms of flexibility, pain relief, and public ...
    Schlagwörter Hamstring muscle ; Knee Osteoartheritis ; Pain ; Manual therapy ; Stretching exercises ; Medicine ; R ; Biology (General) ; QH301-705.5
    Thema/Rubrik (Code) 796
    Sprache Englisch
    Erscheinungsdatum 2023-12-01T00:00:00Z
    Verlag PeerJ Inc.
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: Comparison of salinity tolerance between Avicenna marina and Rhizophora mucronata Karachi coast, Pakistan

    Maria Ashraf / Fuad Muhammad / Jafron Wasiq Hidayat / Muhammad Yaseen / Muhammad Ayyaz / Waqar Ahmed / Muhammad Sohail Anwar / Kamil Ahmed

    Journal of Bioresources and Environmental Sciences, Vol 2, Iss 3, Pp 89-

    2023  Band 99

    Abstract: Mangrove propagule size variation is an important factor in their survival. The main aim of this study was to determine the productivity and identify the comparison between Avicenna marina and Rhizophora mucronata. However, it is less studied about the ... ...

    Abstract Mangrove propagule size variation is an important factor in their survival. The main aim of this study was to determine the productivity and identify the comparison between Avicenna marina and Rhizophora mucronata. However, it is less studied about the comparison of mangrove species and their salt tolerance in terms of seedling establishment of propagules. We investigated the propagules size variation of Avicennia marina and Rhizophora mucronata from the Indus delta and were grown in the polythene bags of 5x10″ filled with silty soil from field nursery. We used salinity and nutrients treatments to propagules to identify the growth rate of mangrove species. The surveying technique was also used to collect the information of mangrove forest from local communities. We detected that Rhizophora mucronata had a higher productivity rate due to the given concentration of 50% sea water. While the Avicennia marina showed a lower decline ratios growth at 25% salinity level with further increases in salinity. Using diffusion porometers and infrared gas analyzers (IRGAs), we revealed that stomatal conductance was higher in Rhizophora mucronata, followed by Avicennia marina. Moreover, our outcomes showed a higher Sodium and chloride ions with the increase in salinity and also demonstrated a higher accumulation in Avicennia marina. Overall, its was found that Avicennia marina is the most salt resistant species and it’s a dominated species in littoral forest. Our outcomes can help us to better understand the green infrastructure design of mangroves, suggesting that selecting multiple techniques ensure many post-tsunami restoration initiatives are encountering problems.
    Schlagwörter avicennia marina ; rhizophora mucronata ; propagules ; salinity ; stomal conductance ; hoagland solution ; seawater ; Environmental sciences ; GE1-350 ; Biology (General) ; QH301-705.5
    Thema/Rubrik (Code) 580
    Sprache Englisch
    Erscheinungsdatum 2023-12-01T00:00:00Z
    Verlag Universitas Diponegoro
    Dokumenttyp Artikel ; Online
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  7. Artikel ; Online: Salinity tolerance of Aegiceras corniculatum and Ceriops tagal in the coastal area of Karachi, Pakistan

    Muhammad Ayyaz / Jafron Wasiq / Fuad Muhammad / Waqar Ahmed / Muhammad Yaseen / Maria Ashraf / Muhammad Abdul Rahman

    Journal of Bioresources and Environmental Sciences, Vol 2, Iss 3, Pp 100-

    2023  Band 108

    Abstract: Indus delta with its coastal zones is the most significant coastal environment in Pakistan for mangroves and associated ecosystems. Mangrove forests are important components for maintenance of ecosystems in severe environments. The purpose of the study ... ...

    Abstract Indus delta with its coastal zones is the most significant coastal environment in Pakistan for mangroves and associated ecosystems. Mangrove forests are important components for maintenance of ecosystems in severe environments. The purpose of the study is to assess the mangrove species' tolerance to salinity. Aegiceras corniculatum and Ceriops tagal (C. tagal) propagules were grown in pots with sandy soil and subirrigated with 25, and 50% nitrogen-fortified saltwater for this research. The propagules were procured from the Indus delta. We raised seedlings for six months as an experiment. Aegiceras corniculatum species behaved moderately in the greenhouse, whereas Ceriops tagal's growth maximum at a salinity of 50% seawater and declined as the salinity increased. Furthermore, Ceriops tagal a non-secretor, accumulated more sodium and chloride ions while severely restricting the availability of other ions. This species might therefore be used to repair intertidal ecosystems, which frequently get freshwater. During a six-month the experimental cultivation period, and measurements were taken of the seedlings' length, weight at planting, and number of leaves. Maximum growth was observed in 50% seawater, and as the salinity increased, it became worse. Three times a week, fresh water was provided to wash away the excess salt. It has been discovered that medium and large-sized propagules function better in a greenhouse environment than small-sized ones. In order for plant seeds to successfully reproduce, the environmental conditions in which they disseminate and settle must be suitable for them. For establishment and dissemination inside the greenhouse environment, the propagules of viviparous mangrove species appear optimal.
    Schlagwörter indus delta ; aegiceras cornicultum ; ceriops tagal ; salinity ; propagules ; mangroves ; ions ; water relations ; Environmental sciences ; GE1-350 ; Biology (General) ; QH301-705.5
    Thema/Rubrik (Code) 580
    Sprache Englisch
    Erscheinungsdatum 2023-12-01T00:00:00Z
    Verlag Universitas Diponegoro
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  8. Artikel ; Online: Antimicrobial, hemagglutination and phytotoxic activity of crude ethanolic and aqueous extracts of Seriphidium kurramense.

    Kafeel, Ahmad / Amjad, Ali / Waqar Ahmed, Afridi / Ramla, Somayya / Muhammad Jawad, Ullah

    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan

    2020  Band 38, Heft 3, Seite(n) 433–438

    Abstract: Objective: To investigate the antimicrobial activity, hemagglutination and phytotoxic activity of crude ethanolic and aqueous extracts of Seriphidium kurramense.: Methods: The extracts were analyzed by agar well diffusion assays against five ... ...

    Abstract Objective: To investigate the antimicrobial activity, hemagglutination and phytotoxic activity of crude ethanolic and aqueous extracts of Seriphidium kurramense.
    Methods: The extracts were analyzed by agar well diffusion assays against five bacterial species: Staphylococcus aureus (S. aureus), methicillin-resistant S. aureus, Escherichia coli, Klebsiella pneumoniae, Bacillus subtilis, and Salmonella typhi. The extracts were also screened against six fungal species-Aspergillus niger, Aspergillus flavus, Alternaria solani, Rhizoctonia solani, Fusarium solani and Pleurotus florida-using the agar tube diffusion method. Additionally, hemagglutination and phytotoxic activities of the crude ethanolic and aqueous extracts were assessed.
    Results: The crude ethanolic and aqueous extracts showed dose-dependent inhibition of the various tested fungal and bacterial strains. No hemagglutination activity was observed. Both the ethanolic and aqueous extracts showed dose-dependent phytotoxic activity toward Lemna minor.
    Conclusion: The crude ethanolic and aqueous extracts of Seriphidium kurramense possess good antimicrobial and phytotoxic activities, but no hemagglutination activity.
    Sprache Englisch
    Erscheinungsdatum 2020-03-10
    Erscheinungsland China
    Dokumenttyp Journal Article
    ZDB-ID 603186-9
    ISSN 2589-451X ; 0254-6272 ; 0255-2922
    ISSN (online) 2589-451X ; 0254-6272
    ISSN 0255-2922
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  9. Artikel ; Online: Caregiver Burden among Parents of Hearing Impaired and Intellectually Disabled Children in Pakistan

    Imran Haider SYED / Waqar Ahmed AWAN / Unaiza Batool SYEDA

    Iranian Journal of Public Health, Vol 49, Iss

    2020  Band 2

    Abstract: Background: Caregiver burden is a multidimensional response to physical, psychological, emotional, social and financial stressors, usually associated with the experience of caring and can be objective or subjective. The objective of current study was to ... ...

    Abstract Background: Caregiver burden is a multidimensional response to physical, psychological, emotional, social and financial stressors, usually associated with the experience of caring and can be objective or subjective. The objective of current study was to explore the caregiver burden among parents of hearing impaired and intellectually challenged children in Pakistan. Methods: A Comparative cross sectional survey was conducted on n=162 parents of hearing impaired (HI) and intellectually challenged (IC) children from July 2018 to February 2019. Convenient sampling technique was used to collect the data from Parents of hearing impaired and intellectually challenged children with age range 1-16 years in National Institute of Rehabilitation Medicine and Al-Farabi Special Education Institute Islamabad. Caregiver Burden Inventory was used to assess the caregiver burden. Results: The results showed a greater need for respite and other services in both groups. Parents of intellectually challenged children need more respite and other services as compared to hearing impaired children (60.62±11.43 ver. 45.74±11.20, p<0.001). A total of 3 (4.0%) parents of hearing impaired children reported rare need for respite and other services, 32(42.7%) reported sometimes and 40(53.3%) reported frequent need. On the other hand 12(13.8%) parents of intellectually disabled children reported sometimes, 66(75.9%) reported quite frequently and 9(10.3%) nearly always a greater need for respite and other services. Conclusion: The parents of hearing impaired or intellectually challenged children face significant burden of their disabled child. In addition, due to cognitive deficits that lead to behavioural abnormalities the parents of intellectually challenged children face more burden and stress.
    Schlagwörter Disability ; Deaf ; Hearing impairment ; Intellectually challenged ; Public aspects of medicine ; RA1-1270
    Thema/Rubrik (Code) 390
    Sprache Englisch
    Erscheinungsdatum 2020-02-01T00:00:00Z
    Verlag Tehran University of Medical Sciences
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  10. Artikel ; Online: Effects of Selected Pharmaceuticals on Freshwater Algal Biofilms in Different Organic Loads

    Waqar Ahmed / Aneela Yasmin / Ayesha Tajammul / Najeebullah Channa / Jamil Ahmed

    Mehran University Research Journal of Engineering and Technology, Vol 39, Iss 3, Pp 541-

    2020  Band 547

    Abstract: The growth pattern of different algal biofilms investigated in the presence of Ibuprofen and Benzoyl Metronidazole in batch reactors at varying organic loads. Study suggests that the inhibition of algal growth is correlated to organic loads in water ... ...

    Abstract The growth pattern of different algal biofilms investigated in the presence of Ibuprofen and Benzoyl Metronidazole in batch reactors at varying organic loads. Study suggests that the inhibition of algal growth is correlated to organic loads in water rather than the concentrations of PhCs (Pharmaceuticals). Mortality of algae was recorded in BG11 media with binary mixtures of PhCs and no growth inhibition was monitored in the activated sludge with PhCs. These outcomes indicate that the presence of PhCs as pollutants in drinking water have severe effect on algal biofilms due to low organic load thus can alter the aquatic ecosystem. Additionally, PhCs might not adversely hinder the growth of microbes in WWTP (Wastewater Treatment Plants) or in waters with high organic loads. Nevertheless, inference of these results to a full-scale WWTP need more evidence through extensive studies using variable organic substrates and PhCs with numerous ranges of organic loads. These findings suggest that PhCs as water contaminant are able to shift microbial ecology in water bodies.
    Schlagwörter Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Science ; Q
    Sprache Englisch
    Erscheinungsdatum 2020-07-01T00:00:00Z
    Verlag Mehran University of Engineering and Technology
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