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  1. Article ; Online: Preface to Journal of Dermatology special issue: Viral diseases in dermatology -recent advances.

    Watanabe, Daisuke

    The Journal of dermatology

    2023  Volume 50, Issue 3, Page(s) 279

    MeSH term(s) Humans ; Dermatology ; Virus Diseases/diagnosis
    Language English
    Publishing date 2023-01-18
    Publishing country England
    Document type Editorial
    ZDB-ID 800103-0
    ISSN 1346-8138 ; 0385-2407
    ISSN (online) 1346-8138
    ISSN 0385-2407
    DOI 10.1111/1346-8138.16717
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Sake yeast symbiosis with lactic acid bacteria and alcoholic fermentation.

    Watanabe, Daisuke

    Bioscience, biotechnology, and biochemistry

    2023  Volume 88, Issue 3, Page(s) 237–241

    Abstract: The yeast Saccharomyces cerevisiae plays a pivotal role in the production of fermented foods by converting sugars in ingredients into ethanol through alcoholic fermentation. However, how accurate is our understanding of its biological significance? ... ...

    Abstract The yeast Saccharomyces cerevisiae plays a pivotal role in the production of fermented foods by converting sugars in ingredients into ethanol through alcoholic fermentation. However, how accurate is our understanding of its biological significance? Although yeast is essential to produce alcoholic beverages and bioethanol, yeast does not yield ethanol for humankind. Yeast obtains energy in the form of ATP for its own vital processes through alcoholic fermentation, which generates ethanol as a byproduct. The production of ethanol may have more significance for yeast, since many other organisms do not produce ethanol, a highly toxic substance, to obtain energy. The key to address this issue has not been found using conventional microbiology, where yeasts are isolated and cultured in pure form. This review focuses on a possible novel role of yeast alcohol fermentation, which is revealed through our recent studies of microbial interactions.
    MeSH term(s) Saccharomyces cerevisiae ; Alcoholic Beverages/analysis ; Lactobacillales ; Symbiosis ; Fermentation ; Ethanol
    Chemical Substances Ethanol (3K9958V90M)
    Language English
    Publishing date 2023-11-17
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 1106450-x
    ISSN 1347-6947 ; 0916-8451
    ISSN (online) 1347-6947
    ISSN 0916-8451
    DOI 10.1093/bbb/zbad167
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4647: Show issues Location:
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  3. Article ; Online: Distinct Frontoparietal Brain Dynamics Underlying the Co-Occurrence of Autism and ADHD.

    Watanabe, Daichi / Watanabe, Takamitsu

    eNeuro

    2023  Volume 10, Issue 7

    Abstract: Previous diagnostic systems precluded the co-existence of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in one person; but, after many clinical reports, the diagnostic criteria were updated to allow their co- ... ...

    Abstract Previous diagnostic systems precluded the co-existence of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in one person; but, after many clinical reports, the diagnostic criteria were updated to allow their co-occurrence. Despite such a clinical change, the neurobiological bases underpinning the comorbidity remain poorly understood, and whether the ASD+ADHD condition is a simple overlap of the two disorders is unknown. Here, to answer this question, we compared the brain dynamics of high-functioning ASD+ADHD children with age-/sex-/IQ-matched pure ASD, pure ADHD, and typically developing (TD) children. Regarding autistic traits, the socio-communicational symptom of the ASD+ADHD children was explained by the same overstable brain dynamics as seen in pure ASD. In contrast, their ADHD-like traits were grounded on a unique neural mechanism that was unseen in pure ADHD: the core symptoms of pure ADHD were associated with the overly flexible whole-brain dynamics that were triggered by the unstable activity of the dorsal-attention network and the left parietal cortex; by contrast, the ADHD-like cognitive instability of the ASD+ADHD condition was correlated with the atypically frequent neural transition along a specific brain state pathway, which was induced by the atypically unstable activity of the frontoparietal control network and the left prefrontal cortex. These observations need to be validated in future studies using more direct and comprehensive behavioral indices, but the current findings suggest that the ASD+ADHD comorbidity is not a mere overlap of the two disorders. Particularly, its ADHD-like traits could represent a unique condition that would need a specific diagnosis and bespoke treatments.
    MeSH term(s) Child ; Humans ; Autistic Disorder ; Attention Deficit Disorder with Hyperactivity/complications ; Autism Spectrum Disorder/complications ; Autism Spectrum Disorder/diagnosis ; Brain/diagnostic imaging ; Prefrontal Cortex/diagnostic imaging
    Language English
    Publishing date 2023-07-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2800598-3
    ISSN 2373-2822 ; 2373-2822
    ISSN (online) 2373-2822
    ISSN 2373-2822
    DOI 10.1523/ENEURO.0146-23.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Adaptation of yeast Saccharomyces cerevisiae to grape-skin environment.

    Watanabe, Daisuke / Hashimoto, Wataru

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 9279

    Abstract: Saccharomyces cerevisiae, an essential player in alcoholic fermentation during winemaking, is rarely found in intact grapes. Although grape-skin environment is unsuitable for S. cerevisiae's stable residence, Saccharomycetaceae-family fermentative yeasts ...

    Abstract Saccharomyces cerevisiae, an essential player in alcoholic fermentation during winemaking, is rarely found in intact grapes. Although grape-skin environment is unsuitable for S. cerevisiae's stable residence, Saccharomycetaceae-family fermentative yeasts can increase population on grape berries after colonization during raisin production. Here, we addressed adaptation of S. cerevisiae to grape-skin ecosystem. The yeast-like fungus Aureobasidium pullulans, a major grape-skin resident, exhibited broad spectrum assimilation of plant-derived carbon sources, including ω-hydroxy fatty acid, arising from degradation of plant cuticles. In fact, A. pullulans encoded and secreted possible cutinase-like esterase for cuticle degradation. When intact grape berries were used as a sole carbon source, such grape-skin associated fungi increased the accessibility to fermentable sugars by degrading and assimilating the plant cell wall and cuticle compounds. Their ability seems also helpful for S. cerevisiae to obtain energy through alcoholic fermentation. Thus, degradation and utilization of grape-skin materials by resident microbiota may account for their residence on grape-skin and S. cerevisiae's possible commensal behaviors. Conclusively, this study focused on the symbiosis between grape-skin microbiota and S. cerevisiae from the perspective of winemaking origin. Such plant-microbe symbiotic interaction may be a prerequisite for triggering spontaneous food fermentation.
    MeSH term(s) Saccharomyces cerevisiae/metabolism ; Vitis/microbiology ; Ecosystem ; Wine/analysis ; Fungi
    Language English
    Publishing date 2023-06-20
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-35734-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Glutathione depression alters cellular mechanisms of skeletal muscle fatigue in early stage of recovery and prolongs force depression in late stage of recovery.

    Watanabe, Daiki / Wada, Masanobu

    American journal of physiology. Regulatory, integrative and comparative physiology

    2023  Volume 325, Issue 2, Page(s) R120–R132

    Abstract: The effects of reduced glutathione (GSH) on skeletal muscle fatigue were investigated. GSH was depressed by buthionine sulfoximine (BSO) (100 mg/kg body wt/day) treatment for 5 days, which decreased GSH content to ∼10%. Male Wistar rats were assigned to ... ...

    Abstract The effects of reduced glutathione (GSH) on skeletal muscle fatigue were investigated. GSH was depressed by buthionine sulfoximine (BSO) (100 mg/kg body wt/day) treatment for 5 days, which decreased GSH content to ∼10%. Male Wistar rats were assigned to the control (
    MeSH term(s) Rats ; Male ; Animals ; Muscle Fatigue/physiology ; Rats, Wistar ; Depression ; Glutathione/pharmacology ; Glutathione/physiology ; Muscle, Skeletal ; Buthionine Sulfoximine/pharmacology
    Chemical Substances Glutathione (GAN16C9B8O) ; Buthionine Sulfoximine (5072-26-4)
    Language English
    Publishing date 2023-05-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603839-6
    ISSN 1522-1490 ; 0363-6119
    ISSN (online) 1522-1490
    ISSN 0363-6119
    DOI 10.1152/ajpregu.00097.2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  6. Article: [Cutaneous Herpesvirus Infection].

    Watanabe, Daisuke

    Brain and nerve = Shinkei kenkyu no shinpo

    2019  Volume 71, Issue 4, Page(s) 302–308

    Abstract: Among human herpes viruses, those known to cause neurological symptoms are the herpes simplex virus (HSV) types 1 and 2 and the varicella-zoster virus (VZV), which remain latent in the dorsal root ganglion. HSV causes herpes labialis, genital herpes, etc. ...

    Abstract Among human herpes viruses, those known to cause neurological symptoms are the herpes simplex virus (HSV) types 1 and 2 and the varicella-zoster virus (VZV), which remain latent in the dorsal root ganglion. HSV causes herpes labialis, genital herpes, etc. VZV causes varicella during the primary infection, and shingles when reactivated. In this review, we present to the typical cases of each disease; in addition, we present several types of diseases that are closely related to neurological diseases.
    MeSH term(s) Ganglia, Spinal/virology ; Herpes Zoster/pathology ; Herpesviridae Infections/pathology ; Herpesvirus 1, Human ; Herpesvirus 2, Human ; Herpesvirus 3, Human ; Humans ; Skin Diseases/virology
    Language Japanese
    Publishing date 2019-05-24
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416201266
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 398: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article: [Herpes Zoster Vaccine].

    Watanabe, Daisuke

    Uirusu

    2019  Volume 68, Issue 1, Page(s) 21–30

    Abstract: Herpes zoster, or shingles, results from the reactivation of latent varicella- zoster virus (VZV) in the dorsal-root or cranial-nerve ganglia, usually decades after primary infection. Herpes zoster is characterized by a vesicular rash with a unilateral ... ...

    Abstract Herpes zoster, or shingles, results from the reactivation of latent varicella- zoster virus (VZV) in the dorsal-root or cranial-nerve ganglia, usually decades after primary infection. Herpes zoster is characterized by a vesicular rash with a unilateral and dermatomal distribution and is almost always accompanied by pain. Herpes zoster is not only skin disease, but also sometimes affects other organs, including central nerve system, eye, and facial nerve. The most common complications, such as postherpetic neuralgia (PHN), are more frequent, severe and impair patients' quality of life. For more than 10 years, in US, EU, and Australia, a live-attenuated vaccine against herpes zoster (Zostavax) containing the Oka VZV strain is licensed for use in adults who are 50 years of age or older. In Japan, a live attenuated varicella vaccine is also licensed for preventing herpes zoster in 2016. Two large randomized multinational efficacy trials (ZOE-50 and ZOE-70) showed that the novel herpes zoster subunit vaccine (shinglix) candidate containing varicella-zoster virus glycoprotein E (gE) and the AS01B adjuvant system reduced the risk of herpes zoster and PHN by more than 90%. This article aimed to review the epidemiology, pathophysiology and complications of herpes zoster and mention the efficacies and problems of the live-attenuated and the new recombinant herpes zoster vaccines.
    MeSH term(s) Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Female ; Herpes Zoster/epidemiology ; Herpes Zoster/prevention & control ; Herpes Zoster/virology ; Herpes Zoster Vaccine ; Herpesvirus 3, Human/pathogenicity ; Herpesvirus 3, Human/physiology ; Humans ; Infant ; Male ; Middle Aged ; Vaccines, Subunit ; Virus Replication ; Young Adult
    Chemical Substances Herpes Zoster Vaccine ; Vaccines, Subunit
    Language Japanese
    Publishing date 2019-05-16
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 603272-2
    ISSN 0042-6857
    ISSN 0042-6857
    DOI 10.2222/jsv.68.21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 266: Show issues Location:
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  8. Article ; Conference proceedings: Safety and efficacy of EUS-guided drainage for liver abscess and biloma: single center experience in a district hospital in Japan

    Hisai, H. / Sakurai, T. / Koshiba, Y. / Watanabe, D.

    Endoscopy

    2023  Volume 55, Issue S 02

    Event/congress ESGE Days 2023, Dublin, Ireland, 2023-04-20
    Language English
    Publishing date 2023-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0043-1766019
    Database Thieme publisher's database

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    Zs.MO 162: Show issues

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  9. Article: Contribution of the Gut Microbiota to Intestinal Fibrosis in Crohn's Disease.

    Watanabe, Daisuke / Kamada, Nobuhiko

    Frontiers in medicine

    2022  Volume 9, Page(s) 826240

    Abstract: In Crohn's disease (CD), intestinal fibrosis is a critical determinant of a patient's prognosis. Although inflammation may be a prerequisite for the initiation of intestinal fibrosis, research shows that the progression or continuation of intestinal ... ...

    Abstract In Crohn's disease (CD), intestinal fibrosis is a critical determinant of a patient's prognosis. Although inflammation may be a prerequisite for the initiation of intestinal fibrosis, research shows that the progression or continuation of intestinal fibrosis can occur independently of inflammation. Thus, once initiated, intestinal fibrosis may persist even if medical treatment controls inflammation. Clearly, an understanding of the pathophysiological mechanisms of intestinal fibrosis is required to diminish its occurrence. Accumulating evidence suggests that the gut microbiota contributes to the pathogenesis of intestinal fibrosis. For example, the presence of antibodies against gut microbes can predict which CD patients will have intestinal complications. In addition, microbial ligands can activate intestinal fibroblasts, thereby inducing the production of extracellular matrix. Moreover, in various animal models, bacterial infection can lead to the development of intestinal fibrosis. In this review, we summarize the current knowledge of the link between intestinal fibrosis in CD and the gut microbiota. We highlight basic science and clinical evidence that the gut microbiota can be causative for intestinal fibrosis in CD and provide valuable information about the animal models used to investigate intestinal fibrosis.
    Language English
    Publishing date 2022-02-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2022.826240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Ca

    Watanabe, Daiki / Nishi, Miyuki / Liu, Feng / Bian, Yuhan / Takeshima, Hiroshi

    American journal of physiology. Cell physiology

    2024  Volume 326, Issue 3, Page(s) C795–C809

    Abstract: Mitsugumin 23 (MG23) has been identified as a ball-shaped cation channel in the sarcoplasmic reticulum (SR) but its physiological role remains unclear. This study aimed to examine the contribution of MG23 to ... ...

    Abstract Mitsugumin 23 (MG23) has been identified as a ball-shaped cation channel in the sarcoplasmic reticulum (SR) but its physiological role remains unclear. This study aimed to examine the contribution of MG23 to Ca
    MeSH term(s) Animals ; Mice ; Cations ; Muscle Fatigue ; Muscle Fibers, Skeletal ; Muscle, Skeletal ; Sarcoplasmic Reticulum
    Chemical Substances Cations ; mitsugumin23 protein, mouse
    Language English
    Publishing date 2024-01-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392098-7
    ISSN 1522-1563 ; 0363-6143
    ISSN (online) 1522-1563
    ISSN 0363-6143
    DOI 10.1152/ajpcell.00440.2023
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