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  1. Article ; Online: Asthma and carotid artery plaques.

    Cardet, Juan Carlos / Weare-Regales, Natalia / Lockey, Richard F

    The Journal of allergy and clinical immunology

    2023  Volume 151, Issue 5, Page(s) 1257–1258

    MeSH term(s) Humans ; Carotid Stenosis ; Inflammation ; Risk Factors ; Asthma
    Language English
    Publishing date 2023-03-02
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2023.02.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.92: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Practical Guidance for Prevention and Management of Glucocorticoid-Induced Osteoporosis for the Allergist/Immunologist.

    Weare-Regales, Natalia / Hudey, Stephanie N / Lockey, Richard F

    The journal of allergy and clinical immunology. In practice

    2021  Volume 9, Issue 5, Page(s) 1841–1850

    Abstract: Osteoporosis is a silent disorder with dire consequences, and glucocorticoid use remains the most common iatrogenic cause illustrated by the fact that 30% to 50% of subjects on such long-term therapy experience fractures (Oimomi M, Nakamichi T, Ohara T, ... ...

    Abstract Osteoporosis is a silent disorder with dire consequences, and glucocorticoid use remains the most common iatrogenic cause illustrated by the fact that 30% to 50% of subjects on such long-term therapy experience fractures (Oimomi M, Nakamichi T, Ohara T, Sakai M, Igaki N, Hata F, et al. Fructose-related glycation. Diabetes Res Clin Pract 1989;7:137-9; Reid IR. Glucocorticoid osteoporosis--mechanisms and management. Eur J Endocrinol 1997;137:209-17). By directly affecting bone quality while actively used, glucocorticoids increase the risk of fracture that is independent of a subject's bone density status at the time (Weinstein RS. True strength. J Bone Miner Res 2000;15:621-5). A large number of subjects seen in an allergy and immunology clinic have asthma, chronic rhinosinusitis, or other chronic inflammatory diseases, necessitating the use of these medications and placing them at higher risk for this disease. Data on the effects of both oral and inhaled glucocorticoids on fracture risk are presented. This review concretizes the importance of osteoporosis, its pathophysiology, and provides practical guidelines to prevent and treat it. Management recommendations are tailored to 2 different age groups. The first group consists of children, adolescents, and adults 40 years or younger with a focus on attaining peak bone mass. The second group consists of adults 40 years or older where the use of imaging modalities and Fracture Risk Assessment Tool scores helps triage subjects into fracture risk categories. Those at moderate to high risk require bone-sparing medications. Universal preventive measures for both groups are reviewed. Complicated and severe cases may need additional expertise by an endocrinologist or rheumatologist.
    MeSH term(s) Adolescent ; Adult ; Allergists ; Bone Density ; Bone and Bones ; Child ; Glucocorticoids/therapeutic use ; Humans ; Osteoporosis/chemically induced ; Osteoporosis/drug therapy ; Osteoporosis/prevention & control
    Chemical Substances Glucocorticoids
    Language English
    Publishing date 2021-01-11
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2020.12.050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 7086: Show issues Location:
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  3. Article ; Online: A Practical Approach to Assist Asthmatics to Lose Weight.

    Kolinsky, Nicholas C / Weare-Regales, Natalia / Lockey, Richard F

    The journal of allergy and clinical immunology. In practice

    2021  Volume 9, Issue 6, Page(s) 2245–2254

    Abstract: Treating patients with obesity, particularly asthmatics, is a complex challenge that requires a unique and individually tailored approach. Obesity, defined by the Centers for Disease Control and Prevention, is a body mass index of 30.0 kg/ ... ...

    Abstract Treating patients with obesity, particularly asthmatics, is a complex challenge that requires a unique and individually tailored approach. Obesity, defined by the Centers for Disease Control and Prevention, is a body mass index of 30.0 kg/m
    MeSH term(s) Adolescent ; Adult ; Asthma/epidemiology ; Body Mass Index ; Diabetes Mellitus, Type 2 ; Humans ; Obesity/epidemiology ; Weight Loss
    Language English
    Publishing date 2021-01-28
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2021.01.016
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 7086: Show issues Location:
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  4. Article ; Online: Hormonal Effects on Asthma, Rhinitis, and Eczema.

    Weare-Regales, Natalia / Chiarella, Sergio E / Cardet, Juan Carlos / Prakash, Y S / Lockey, Richard F

    The journal of allergy and clinical immunology. In practice

    2022  Volume 10, Issue 8, Page(s) 2066–2073

    Abstract: Hormones significantly influence the pathogenesis of asthma, rhinitis, and eczema. This review aims to summarize relevant clinical considerations for practicing allergists and immunologists. The first section reviews the effects of sex hormones: estrogen, ...

    Abstract Hormones significantly influence the pathogenesis of asthma, rhinitis, and eczema. This review aims to summarize relevant clinical considerations for practicing allergists and immunologists. The first section reviews the effects of sex hormones: estrogen, progesterone, and testosterone. The second concerns insulin production in the context of type 1 and type 2 diabetes. The third concludes with a discussion of thyroid and adrenal pathology in relationship to asthma, rhinitis, and eczema.
    MeSH term(s) Asthma/etiology ; Dermatitis, Atopic/complications ; Diabetes Mellitus, Type 2 ; Eczema ; Humans ; Prevalence ; Rhinitis/complications
    Language English
    Publishing date 2022-04-15
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2022.04.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 7086: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Clinical Impact of Initiation of U-500 Insulin vs Continuation of U-100 Insulin in Subjects With Diabetes.

    Ramirez, Alejandro / Weare-Regales, Natalia / Domingo, Anthony / Villafranca, Arnaldo / Valdez, Krystal A / Velez, C Marcela / Foulis, Philip / Gomez-Daspet, Joaquin

    Federal practitioner : for the health care professionals of the VA, DoD, and PHS

    2021  Volume 38, Issue 3, Page(s) e15–e21

    Abstract: Background: The prevalence of obesity and diabetes mellitus (DM) has each increased drastically according to the Centers for Disease Control and Prevention. Growth of severe insulinresistant DM is predicted. U-500 insulin is highly concentrated and can ... ...

    Abstract Background: The prevalence of obesity and diabetes mellitus (DM) has each increased drastically according to the Centers for Disease Control and Prevention. Growth of severe insulinresistant DM is predicted. U-500 insulin is highly concentrated and can replace less concentrated formulations in patients that need high insulin dosages. The aim of this study was to compare clinical outcomes of U-500 and U-100 insulin regimens in veterans with obesity and insulin resistance.
    Methods: A single-site retrospective chart analysis of adult subjects was conducted from July 2002 to June 2011. Data for repeated measures spanned a period from 3 months before the intervention (baseline) through 12 months afterward. The main outcome was the variation in hemoglobin A
    Results: A total of 142 subjects (68 taking U-500 and 74 taking U-100) were included. Baseline characteristics were similar between the groups, except for weight, which was higher among U-500 subjects. Mean HbA
    Conclusions: U-500 insulin, when compared with U-100 insulin regimens, led to a statistically significant reduction in HbA
    Language English
    Publishing date 2021-03-22
    Publishing country United States
    Document type Journal Article
    ISSN 1078-4497
    ISSN 1078-4497
    DOI 10.12788/fp.0105
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Nutritional Literacy Among Uninsured Patients With Diabetes Mellitus: A Free Clinic Study.

    Rivera Rivero, Bianshly / Makarova, Alena / Sidig, Dina / Niazi, Saniya / Abddelgader, Rasha / Mirza, Sabbir / Joud, Hadi / Urfi, Mustafa / Ahmed, Abdillahi / Jureyda, Omar / Khan, Firaas / Swanson, Justin / Siddique, Maqsood / Weare-Regales, Natalia / Mirza, Abu-Sayeef

    Cureus

    2021  Volume 13, Issue 7, Page(s) e16355

    Abstract: Objective Evaluate nutrition literacy in uninsured subjects with diabetes mellitus (DM) who presented to free diabetes management classes.  Design  This single-site, cross-sectional observational study recruited thirty subjects from a free clinic for ... ...

    Abstract Objective Evaluate nutrition literacy in uninsured subjects with diabetes mellitus (DM) who presented to free diabetes management classes.  Design  This single-site, cross-sectional observational study recruited thirty subjects from a free clinic for uninsured patients to attend diabetes mellitus, self-management classes. Before starting the classes, DM care-related data were collected, and subjects were administered the Nutrition Literacy Assessment Instrument (NLit). The assessment covers six subscales in nutrition and categorizes results into three possible categories: the likelihood of poor nutrition literacy (NLit Score ≤ 44), the possibility of poor nutrition literacy (NLit Score- 45-57), and the likelihood of good nutrition literacy (NLit score ≥ 58).  Results  Median glycated haemoglobin (HbA1c) was 7.45% for study participants. The mean NLit score was 38.1 (SD ± 9.4), correlating with a likelihood of poor nutrition literacy. All participants had either likelihood or the possibility of poor nutrition literacy based on the NLit Assessment. There were no participants who scored in the range of likelihood of good nutrition literacy. Subjects who scored in the range of likelihood of poor nutrition literacy had a significantly higher mean HbA1c (8.6 %) than those who scored in the possibility of poor nutrition literacy (6.9 %, p=0.005). Conclusions Poor nutrition literacy is associated with worse glycemic control among uninsured subjects with diabetes mellitus.
    Language English
    Publishing date 2021-07-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.16355
    Database MEDical Literature Analysis and Retrieval System OnLINE

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