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  1. Article ; Online: Muscle-sparing thoracotomy: Anatomy and technique.

    Pumphrey, Oliver / Limbachia, Devan / Hawari, Mohammad / Weaver, Helen / Burnside, Nathan

    Multimedia manual of cardiothoracic surgery : MMCTS

    2021  Volume 2021

    Abstract: The thoracotomy incision is essential for many thoracic surgery procedures. A number of different variations exist, and different techniques can be used, depending both on the patient and on the technical factors. The muscle-sparing technique was first ... ...

    Abstract The thoracotomy incision is essential for many thoracic surgery procedures. A number of different variations exist, and different techniques can be used, depending both on the patient and on the technical factors. The muscle-sparing technique was first described by Noirclerc et al. in 1973. [1] Initially, it was thought that preservation of the muscular structures compared with the results of a traditional posterolateral thoracotomy, in which the latissimus dorsi and sometimes the serratus anterior are often divided, would benefit long-term outcomes.  However, subsequent study results  have not demonstrated any difference in postoperative outcomes. The unequivocal benefit of a muscle-sparing approach is to preserve the latissimus dorsi for any future intervention, such as a procedure involving the chest wall and the intrathoracic flaps. In this video tutorial, we describe our approach to this commonly used incision, including the anatomy and the technical aspects used to provide optimal operative exposure and minimal postoperative complications while preserving the underlying musculature.
    MeSH term(s) Female ; Humans ; Intercostal Muscles/surgery ; Middle Aged ; Reconstructive Surgical Procedures/methods ; Superficial Back Muscles/anatomy & histology ; Superficial Back Muscles/surgery ; Surgical Flaps ; Thoracic Wall/anatomy & histology ; Thoracic Wall/surgery ; Thoracotomy/methods
    Language English
    Publishing date 2021-03-09
    Publishing country England
    Document type Case Reports ; Video-Audio Media
    ZDB-ID 2280156-X
    ISSN 1813-9175 ; 1813-9175
    ISSN (online) 1813-9175
    ISSN 1813-9175
    DOI 10.1510/mmcts.2021.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: The Awakener

    Weaver, Helen

    A Memoir of Jack Kerouac and the Fifties

    2014  

    Abstract: ... Helen Weaver's insightful and riveting memoir of love and friendship with Jack Kerouac and the Beats ... ...

    Abstract
    Helen Weaver's insightful and riveting memoir of love and friendship with Jack Kerouac and the Beats.

    Language English
    Size Online-Ressource (318 p)
    Publisher City Lights Publishers
    Publishing place New York
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9780872865051 ; 0872865053
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  3. Article: Lung volume reduction surgery in patients with low diffusion capacity.

    Weaver, Helen / Greening, Neil J / Rathinam, Sridhar

    Journal of thoracic disease

    2019  Volume 11, Issue Suppl 3, Page(s) S234–S236

    Language English
    Publishing date 2019-03-04
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2019.01.91
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Use of Intraaortic Balloon Pumps in Acute Type A Aortic Dissection.

    Weaver, Helen / Farid, Shakil / Nashef, Samer / Catarino, Pedro

    The Annals of thoracic surgery

    2017  Volume 104, Issue 4, Page(s) e321–e322

    Abstract: Cardiac failure may occur after repair of type A aortic dissections and contributes significantly to mortality. The use of an intraaortic balloon pump (IABP) for circulatory support in these patients is traditionally considered contraindicated because of ...

    Abstract Cardiac failure may occur after repair of type A aortic dissections and contributes significantly to mortality. The use of an intraaortic balloon pump (IABP) for circulatory support in these patients is traditionally considered contraindicated because of concerns over extension of the residual dissection flap or aortic rupture. We propose that the use of an IABP may be appropriate and safe to improve cardiac function in patients after type A dissection repair. The two cases presented here contribute to increasing the body of evidence to support the appropriate use of IABP in these patients.
    MeSH term(s) Acute Disease ; Adult ; Aged ; Aneurysm, Dissecting/diagnostic imaging ; Aneurysm, Dissecting/mortality ; Aneurysm, Dissecting/surgery ; Aortic Aneurysm, Thoracic/diagnostic imaging ; Aortic Aneurysm, Thoracic/mortality ; Aortic Aneurysm, Thoracic/surgery ; Autopsy ; Critical Illness ; Female ; Heart Failure/diagnostic imaging ; Heart Failure/etiology ; Heart Failure/mortality ; Heart Function Tests ; Humans ; Intra-Aortic Balloon Pumping/adverse effects ; Intra-Aortic Balloon Pumping/methods ; Magnetic Resonance Angiography ; Male ; Marfan Syndrome/complications ; Marfan Syndrome/diagnosis ; Patient Safety ; Patient Selection ; Risk Assessment ; Sampling Studies ; Survival Rate ; Treatment Outcome
    Language English
    Publishing date 2017-10
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2017.05.079
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Uniportal subxiphoid video-assisted thoracoscopic bilateral segmentectomy for synchronous bilateral lung adenocarcinomas.

    Aresu, Giuseppe / Weaver, Helen / Wu, Liang / Lin, Lei / Sponga, Sandro / Jiang, Gening / Jiang, Lei

    Journal of visualized surgery

    2016  Volume 2, Page(s) 170

    Abstract: Uniportal subxiphoid video assisted bilateral segmentectomy is a minimally invasive option for the treatment of synchronous bilateral lung lesions. Its advantages over conventional multiportal or uniportal video assisted thoracoscopic surgery include ... ...

    Abstract Uniportal subxiphoid video assisted bilateral segmentectomy is a minimally invasive option for the treatment of synchronous bilateral lung lesions. Its advantages over conventional multiportal or uniportal video assisted thoracoscopic surgery include avoidance of damage to the intercostal neurovascular bundle and allowance of bilateral lesion resection as a combined procedure via a single incision. This article presents a case from our centre to describe our surgical technique for this procedure.
    Language English
    Publishing date 2016-11-30
    Publishing country China
    Document type Case Reports
    ISSN 2221-2965
    ISSN 2221-2965
    DOI 10.21037/jovs.2016.11.02
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The Shanghai Pulmonary Hospital uniportal subxiphoid approach for lung segmentectomies.

    Aresu, Giuseppe / Weaver, Helen / Wu, Liang / Lin, Lei / Jiang, Gening / Jiang, Lei

    Journal of visualized surgery

    2016  Volume 2, Page(s) 172

    Abstract: Background: Lung segmentectomy may be considered an oncologic equivalent treatment to lobectomy for non-small cell lung cancer (NSCLC) sized 20 mm or smaller. Subxiphoid uniportal video-assisted thoracoscopic surgery (VATS) could further improve the ... ...

    Abstract Background: Lung segmentectomy may be considered an oncologic equivalent treatment to lobectomy for non-small cell lung cancer (NSCLC) sized 20 mm or smaller. Subxiphoid uniportal video-assisted thoracoscopic surgery (VATS) could further improve the surgical outcome reducing the surgical stress and completely avoiding the intercostal nerve injury. The aim of this manuscript is to illustrate the Shanghai Pulmonary Hospital surgical techniques for uniportal subxiphoid VATS (SVATS) segmentectomies.
    Methods: A total of 79 consecutive patients underwent 84 subxiphoid segmentectomies for malignant or benign pulmonary diseases between September 2014 and January 2016. We here illustrate the surgical techniques and the early results.
    Results: There were 45 segmentectomies in right-side group and 39 segmentectomies left-side group. The mean operation time was 2.38±0.77 hours, and mean operative blood loss was 126.09±136.17 mL. Nine segmentectomies (10.7%) had an intra-operative change of procedure and four were converted to thoracotomy, one had a lobectomy rather than a segmentectomy and four were converted to conventional VATS lobectomy. A total of 12 patients (15.1%) had postoperative complications, including 1 hematoma, 4 prolonged air-leaks and 8 arrhythmias.
    Conclusions: In the presented series that included our learning curve period we have experienced relative low conversion rates and few post-operatively complications showing that, SVATS segmentectomy can be considered a safe procedure with a relative low rate early post-operative complication.
    Language English
    Publishing date 2016-12-02
    Publishing country China
    Document type Journal Article
    ISSN 2221-2965
    ISSN 2221-2965
    DOI 10.21037/jovs.2016.11.07
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Spontaneous splenic rupture: A rare life-threatening condition; Diagnosed early and managed successfully.

    Weaver, Helen / Kumar, Vishal / Spencer, Kate / Maatouk, Mohamed / Malik, Sohail

    The American journal of case reports

    2013  Volume 14, Page(s) 13–15

    Abstract: Background: Splenic rupture is a potentially life-threatening condition, often associated with chest or abdominal trauma. Spontaneous rupture is very rare and is usually reported as being secondary to underlying pathological conditions.: Case report: ...

    Abstract Background: Splenic rupture is a potentially life-threatening condition, often associated with chest or abdominal trauma. Spontaneous rupture is very rare and is usually reported as being secondary to underlying pathological conditions.
    Case report: We discuss the case of a 56 year old man who presented with sudden onset left-sided abdominal pain, with no history of trauma.
    Conclusions: A computed tomography (CT) of the abdomen revealed a ruptured spleen with free fluid in the abdomen. Conservative management was ineffective and the patient underwent laparotomy and splenectomy, followed by routine post-splenectomy management. He was discharged home and remains well.
    Language English
    Publishing date 2013-01-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.883739
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Uniportal subxiphoid video-assisted thoracoscopic approach for thymectomy: a case series.

    Weaver, Helen / Ali, Jason M / Jiang, Lei / Yang, Chenlu / Wu, Liang / Jiang, Gening / Aresu, Giuseppe

    Journal of visualized surgery

    2017  Volume 3, Page(s) 169

    Abstract: Background: Minimally invasive techniques are becoming increasingly popular in thoracic surgery. Although median sternotomy is the traditional approach for thymectomy, video-assisted thoracoscopic surgery (VATS) approaches now predominate. This study ... ...

    Abstract Background: Minimally invasive techniques are becoming increasingly popular in thoracic surgery. Although median sternotomy is the traditional approach for thymectomy, video-assisted thoracoscopic surgery (VATS) approaches now predominate. This study reports a case series of the novel uniportal subxiphoid-VATS approach to extended thymectomy.
    Methods: Over the period of study (October 2014-January 2017) 17 patients underwent uniportal subxiphoid-VATS extended thymectomy for a thymic nodule at the Shanghai Pulmonary Centre. Ten patients were female, and the mean age of the cohort was 55 years. The mean size of nodule was 23.6 mm.
    Results: The mean operative duration was 2.5 hours, with one conversion to thoracotomy for bleeding. The mean operative blood loss was 115 mL. The median length of hospital stay was 4 days. There were no episodes of phrenic nerve palsies. The 30-day survival was 100%.
    Conclusions: Uniportal subxiphoid-VATS is a feasible and safe surgical approach to extended thymectomy in selected patients, with good post-operative outcomes.
    Language English
    Publishing date 2017-11-17
    Publishing country China
    Document type Journal Article
    ISSN 2221-2965
    ISSN (online) 2221-2965
    DOI 10.21037/jovs.2017.10.16
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Oxidative stress and vein graft failure: a focus on NADH oxidase, nitric oxide and eicosanoids.

    Weaver, Helen / Shukla, Nilima / Ellinsworth, David / Jeremy, Jamie Y

    Current opinion in pharmacology

    2012  Volume 12, Issue 2, Page(s) 160–165

    Abstract: Recent interest has focused on superoxide and the upregulation of NADPH oxidase expression in the aetiology of vein graft failure. Implantation of saphenous vein grafts promotes upregulation of NADPH oxidase through a number of distinct interrelated ... ...

    Abstract Recent interest has focused on superoxide and the upregulation of NADPH oxidase expression in the aetiology of vein graft failure. Implantation of saphenous vein grafts promotes upregulation of NADPH oxidase through a number of distinct interrelated mechanisms: (a) endothelial denudation, (b) factors released by adherent platelets, monocytes and neutrophils, (c) hypoxia and (d) altered prostacyclin (PGI(2)) and enhanced isoprostane formation. These, in turn, impact on neointima (NI) formation (vascular smooth muscle cell [VSMC] replication and migration) and metalloproteinase (MMP) expression, key events in vein graft thickening. NADPH oxidase in the aetiology of vein graft failure will be discussed in this review with particular reference to nitric oxide and eicosanoids and related drugs that inhibit its activity and expression.
    MeSH term(s) Animals ; Coronary Artery Bypass/adverse effects ; Eicosanoids/metabolism ; Enzyme Inhibitors/therapeutic use ; Humans ; Multienzyme Complexes/antagonists & inhibitors ; Multienzyme Complexes/metabolism ; NADH, NADPH Oxidoreductases/antagonists & inhibitors ; NADH, NADPH Oxidoreductases/metabolism ; Neointima/metabolism ; Neointima/prevention & control ; Nitric Oxide/metabolism ; Oxidative Stress ; Thrombosis/metabolism ; Thrombosis/prevention & control
    Chemical Substances Eicosanoids ; Enzyme Inhibitors ; Multienzyme Complexes ; Nitric Oxide (31C4KY9ESH) ; NADH oxidase (EC 1.6.-) ; NADH, NADPH Oxidoreductases (EC 1.6.-)
    Language English
    Publishing date 2012-04
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2037057-X
    ISSN 1471-4973 ; 1471-4892
    ISSN (online) 1471-4973
    ISSN 1471-4892
    DOI 10.1016/j.coph.2012.01.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Occupational therapy for epidermolysis bullosa: clinical practice guidelines.

    Chan, Jennifer M / Weisman, Amy / King, Alex / Maksomski, Susan / Shotwell, Carrissa / Bailie, Claire / Weaver, Helen / Bodan, Rebecca / Guerrero, Estrella / Zmazek, Matija / Khuu, Phuong

    Orphanet journal of rare diseases

    2019  Volume 14, Issue 1, Page(s) 129

    Abstract: The purpose of this article is to summarize the Dystrophic Epidermolysis Bullosa Research Association (DEBRA) International evidence-based Clinical Practice Guidelines (CPGs) for the provision of occupational therapy (OT) for children and adults living ... ...

    Abstract The purpose of this article is to summarize the Dystrophic Epidermolysis Bullosa Research Association (DEBRA) International evidence-based Clinical Practice Guidelines (CPGs) for the provision of occupational therapy (OT) for children and adults living with inherited epidermolysis bullosa (EB). This is a rare genetic disorder characterized by skin fragility leading to blister formation occurring spontaneously or following minor trauma. Current OT practice for persons with EB is based on anecdotal care, clinical expertise and trial and error with collaboration between caregiver and patient. Intervention based on research is needed to establish a foundation of knowledge to guide international practitioners to create and improve standards of care and to be able to work effectively with those living with the rare diagnosis of this condition.This CPG was created by an international panel with expertise working with persons with EB. The panel was made up of 11 members including OT's, a physiotherapist, a medical doctor, social worker, person with EB and a carer of a person with EB. It describes the development of recommendations for 5 outcomes determined by survey of persons with EB, caregivers, and experienced healthcare professionals. The outcomes include independence in activities of daily living (ADL), independence in instrumental ADL, maximization of hand function (non-surgical), fine motor development and retention, and oral feeding skills. The recommendations are supplemented with additional files that include photos and specific examples to further guide occupational therapists or, in situations where an OT is not available, other members of the healthcare team.As the disorder of EB is rare, evidence-based CPGs are needed to provide a base of knowledge and practice for OTs throughout the world with the goal of providing quality care to patients, while improving their functional independence and quality of life. In addition, this information is valuable as a basis for further research.
    MeSH term(s) Activities of Daily Living ; Adolescent ; Child ; Child, Preschool ; Epidermolysis Bullosa/therapy ; Female ; Humans ; Male ; Occupational Therapy/methods ; Quality of Life
    Language English
    Publishing date 2019-06-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ISSN 1750-1172
    ISSN (online) 1750-1172
    DOI 10.1186/s13023-019-1059-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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