Article: Imbruvica
British journal of nursing (Mark Allen Publishing)
2017 Volume 26, Issue 10, Page(s) S20–S25
Abstract: Single-agent ibrutinib is an effective therapy for three types of non-Hodgkin lymphoma: chronic lymphocytic leukaemia (CLL) and small lymphocytic lymphoma, both in relapsed and refractory cases and as a frontline treatment; relapsed and refractory mantle ...
| Abstract | Single-agent ibrutinib is an effective therapy for three types of non-Hodgkin lymphoma: chronic lymphocytic leukaemia (CLL) and small lymphocytic lymphoma, both in relapsed and refractory cases and as a frontline treatment; relapsed and refractory mantle cell lymphoma; and Waldenstrom's macroglobulinaemia in patients who have been treated previously with a different medication. This novel agent has changed the landscape for the aforementioned three subtypes of lymphoma therapies as an oral alternative to traditional chemoimmunotherapy. You&i™ is a no-cost support programme, funded by Janssen, that connects patients taking Imbruvica with a nurse who can answer their questions and help address treatment challenges. This programme offers patients information about their disease, their treatment regimen and side effects management by telephone. The You&i programme was tested at an NHS hospital. Case studies of patients and feedback from health professionals who have used this service show its potential benefits to the patient experience and service delivery. |
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| MeSH term(s) | Agammaglobulinaemia Tyrosine Kinase ; Aged ; Antineoplastic Agents/therapeutic use ; Drug Industry ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy ; Leukemia, Lymphocytic, Chronic, B-Cell/nursing ; Lymphoma, Mantle-Cell/drug therapy ; Lymphoma, Mantle-Cell/nursing ; Lymphoma, Non-Hodgkin/drug therapy ; Lymphoma, Non-Hodgkin/nursing ; Male ; Nurses ; Patient Education as Topic ; Protein-Tyrosine Kinases/antagonists & inhibitors ; Pyrazoles/therapeutic use ; Pyrimidines/therapeutic use ; State Medicine ; Telephone ; United Kingdom | |||||
| Chemical Substances | Antineoplastic Agents ; Pyrazoles ; Pyrimidines ; ibrutinib (1X70OSD4VX) ; Protein-Tyrosine Kinases (EC 2.7.10.1) ; Agammaglobulinaemia Tyrosine Kinase (EC 2.7.10.2) | |||||
| Language | English | |||||
| Publishing date | 2017-05-23 | |||||
| Publishing country | England | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 1119191-0 | |||||
| ISSN | 0966-0461 | |||||
| ISSN | 0966-0461 | |||||
| DOI | 10.12968/bjon.2017.26.10.S20 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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