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Article ; Online: Test-Retest Reliability and Minimal Detectable Change of Four Cognitive Tests in Community-Dwelling Older Adults.

Webb, Katherine L / Ryan, Joanne / Wolfe, Rory / Woods, Robyn L / Shah, Raj C / Murray, Anne M / Orchard, Suzanne G / Storey, Elsdon

Journal of Alzheimer's disease : JAD

2022 Volume 87, Issue 4, Page(s) 1683–1693

Abstract: Background: Cognitive test-retest reliability measures can be used to evaluate meaningful changes in scores.: Objective: This analysis aimed to develop a comprehensive set of test-retest reliability values and minimal detectable change (MDC) values ... ...

Abstract	Background: Cognitive test-retest reliability measures can be used to evaluate meaningful changes in scores. Objective: This analysis aimed to develop a comprehensive set of test-retest reliability values and minimal detectable change (MDC) values for a cognitive battery for community-dwelling older individuals in Australia and the U.S., for use in clinical practice. Methods: Cognitive scores collected at baseline and year 1, in the ASPirin in Reducing Events in the Elderly clinical trial were used to calculate intraclass correlation coefficients (ICC) for four tests: Modified Mini-Mental State examination (3MS), Hopkins Verbal Learning Test-Revised (HVLT-R), single-letter Controlled Oral Word Association Test (COWAT-F), and Symbol Digit Modalities Test (SDMT). 16,956 participants aged 70 years and over (65 years and over for U.S. minorities) were included. ICCs were used to calculate MDC values for eight education and ethno-racial subgroups. Results: All four cognitive tests had moderate (ICC > 0.5) to good (ICC > 0.7) test-retest reliability. ICCs ranged from 0.53 to 0.63 (3MS), 0.68 to 0.77 (SDMT), 0.56 to 0.64 (COWAT-F), 0.57 to 0.69 (HVLT-R total recall), and 0.57 to 0.70 (HVLT-R delayed recall) across the subgroups. MDC values ranged from 6.60 to 9.95 (3MS), 12.42 to 15.61 (SDMT), 6.34 to 8.34 (COWAT-F), 8.13 to 10.85 (HVLT-R total recall), and 4.00 to 5.62 (HVLT-R delayed recall). Conclusion: This large cohort of older individuals provides test-retest reliability and MDC values for four widely employed tests of cognitive function. These results can aid interpretation of cognitive scores and decline instead of relying on cross-sectional normative data alone.
MeSH term(s)	Aged ; Aged, 80 and over ; Cognition ; Cross-Sectional Studies ; Humans ; Independent Living ; Neuropsychological Tests ; Reproducibility of Results
Language	English
Publishing date	2022-04-25
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
ZDB-ID	1440127-7
ISSN	1875-8908 ; 1387-2877
ISSN (online)	1875-8908
ISSN	1387-2877
DOI	10.3233/JAD-215564
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Article ; Online: The effect of cannabis on prostate-specific antigen level among men in the United States: results from the National Health and Nutrition Examination Survey.

Weng, Chien-Hsiang / Wieland, Daniel R / Luo, Xun / Webb, Katherine L / Papandonatos, George D

World journal of urology

2020 Volume 39, Issue 12, Page(s) 4509–4510

MeSH term(s)	Aged ; Cannabinoids/pharmacology ; Cannabis ; Humans ; Male ; Nutrition Surveys ; Prostate-Specific Antigen/blood ; Prostate-Specific Antigen/drug effects ; Prostatic Neoplasms/blood ; United States
Chemical Substances	Cannabinoids ; Prostate-Specific Antigen (EC 3.4.21.77)
Language	English
Publishing date	2020-09-19
Publishing country	Germany
Document type	Letter
ZDB-ID	380333-8
ISSN	1433-8726 ; 0724-4983
ISSN (online)	1433-8726
ISSN	0724-4983
DOI	10.1007/s00345-020-03456-w
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Article ; Online: Arterial Wall Penetration Forces in Needles versus Cannulas.

Pavicic, Tatjana / Webb, Katherine L / Frank, Konstantin / Gotkin, Robert H / Tamura, Bhertha / Cotofana, Sebastian

Plastic and reconstructive surgery

2019 Volume 143, Issue 3, Page(s) 504e–512e

Abstract: Background: If safety is defined as the diminished ability to penetrate facial arteries, the goal of this study was to investigate whether different-sized cannulas are safer than correspondingly sized needles for the application of facial soft-tissue ... ...

Abstract	Background: If safety is defined as the diminished ability to penetrate facial arteries, the goal of this study was to investigate whether different-sized cannulas are safer than correspondingly sized needles for the application of facial soft-tissue fillers. Methods: Two hundred ninety-four penetration procedures of the facial and superficial temporal arteries were performed in four fresh frozen cephalic specimens using both needles (20-, 22-, 25-, and 27-gauge) and cannulas (22-, 25-, and 27-gauge). Continuously increasing force was applied and measured until intraarterial penetration occurred. Results: No statistically significant differences were detected when comparing forces required to penetrate the facial arterial vasculature between different sexes, arteries, or sides of the face (all p > 0.05). Forces needed to penetrate significantly (p < 0.001) decreased with smaller diameter needles (20-gauge, 1.12 ± 0.29 N; 22-gauge, 1.08 ± 0.25 N; 25-gauge, 0.69 ± 0.24 N; and 27-gauge, 0.70 ± 0.29 N) and in cannulas (22-gauge, 1.50 ± 0.31 N; 25-gauge, 1.04 ± 0.36 N; and 27-gauge, 0.78 ± 0.35 N). Comparing 27-gauge injectors, no statistically significant difference was detected between needles and cannulas; an artery could be penetrated with a similar force independent of whether the injector was a needle or a cannula (0.70 ± 0.29 N versus 0.78 ± 0.35 N; p = 0.558). Conclusions: Cannulas, in all measured sizes except 27-gauge, required greater forces for intraarterial penetration compared with correspondingly sized needles, confirming the safety of 22- and 25-gauge cannulas; 27-gauge cannulas, however, required similar forces as 27-gauge needles, indicating that 27-gauge cannulas are not safer than 27-gauge needles. Clinical question/level of evidence: Therapeutic, V.
MeSH term(s)	Aged ; Aged, 80 and over ; Cadaver ; Cannula/adverse effects ; Cosmetic Techniques/adverse effects ; Cosmetic Techniques/instrumentation ; Dermal Fillers/administration & dosage ; Equipment Design ; Face/blood supply ; Female ; Humans ; Injections, Subcutaneous/instrumentation ; Male ; Needles/adverse effects ; Temporal Arteries/injuries
Chemical Substances	Dermal Fillers
Language	English
Publishing date	2019-01-28
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Video-Audio Media
ZDB-ID	208012-6
ISSN	1529-4242 ; 0032-1052 ; 0096-8501
ISSN (online)	1529-4242
ISSN	0032-1052 ; 0096-8501
DOI	10.1097/PRS.0000000000005321
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Article ; Online: GFR Variability, Survival, and Cardiovascular Events in Older Adults.

Fravel, Michelle A / Ernst, Michael E / Webb, Katherine L / Wetmore, James B / Wolfe, Rory / Woods, Robyn L / Reid, Christopher M / Chowdhury, Enayet / Murray, Anne M / Polkinghorne, Kevan R

Kidney medicine

2022 Volume 5, Issue 2, Page(s) 100583

Abstract: Rationale & objective: Variability in estimated glomerular filtration rate (eGFR) over time is often observed, but it is unknown whether this variation is clinically important. We investigated the association between eGFR variability and survival free ... ...

Abstract	Rationale & objective: Variability in estimated glomerular filtration rate (eGFR) over time is often observed, but it is unknown whether this variation is clinically important. We investigated the association between eGFR variability and survival free of dementia or persistent physical disability (disability-free survival) and cardiovascular disease (CVD) events (myocardial infarction, stroke, hospitalization for heart failure, or CVD death). Study design: Post hoc analysis. Setting & participants: 12,549 participants of the ASPirin in Reducing Events in the Elderly trial. Participants were without documented dementia, major physical disability, previous CVD, and major life-limiting illness at enrollment. Predictors: eGFR variability. Outcomes: Disability-free survival and CVD events. Analytical approach: eGFR variability was estimated using the standard deviation of eGFR measurements obtained from participants' baseline, first, and second annual visits. Associations between tertiles of eGFR variability with disability-free survival and CVD events occurring after the eGFR variability estimation period were examined. Results: During median follow-up of 2.7 years after the second annual visit, 838 participants died, developed dementia, or acquired a persistent physical disability; 379 had a CVD event. The highest tertile of eGFR variability had an increased risk of death/dementia/disability (HR, 1.35; 95% CI, 1.14-1.59) and CVD events (HR, 1.37; 95% CI, 1.06-1.77) compared with the lowest tertile after covariate adjustment. These associations were present in patients with and without chronic kidney disease at baseline. Limitations: Limited representation of diverse demographics. Conclusions: In older, generally healthy adults, higher variability in eGFR over time predicts increased risk of future death/dementia/disability and CVD events.
Language	English
Publishing date	2022-12-12
Publishing country	United States
Document type	Journal Article
ISSN	2590-0595
ISSN (online)	2590-0595
DOI	10.1016/j.xkme.2022.100583
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Article ; Online: Treating the Lips and Its Anatomical Correlate in Respect to Vascular Compromise.

Ghannam, Sahar / Sattler, Sonja / Frank, Konstantin / Freytag, David L / Webb, Katherine L / Devineni, Aditya / Cotofana, Sebastian

Facial plastic surgery : FPS

2019 Volume 35, Issue 2, Page(s) 193–203

Abstract: Treating the lips to increase facial attractiveness and youthfulness is challenging when trying to consider ethnic differences in an increasingly more diverse society. Multiple injection techniques are currently available for treating lip contour and ... ...

Abstract	Treating the lips to increase facial attractiveness and youthfulness is challenging when trying to consider ethnic differences in an increasingly more diverse society. Multiple injection techniques are currently available for treating lip contour and volume, but a validation in the cadaveric model under the aspects of safety has not been performed yet. The injection techniques presented in this study are based on the experience and personal selection of the authors. The authors have assessed, treated, and evaluated for more than 20 years patients from the Middle East and Central Europe. Cadaveric verification was performed for each of the presented techniques to identify the positioning of the injected product inside the lips and its relation to the superior/inferior labial arteries. The results of the anatomic analyses revealed that in 58.3% of the performed injections, the product was placed close to the superior/inferior labial arteries. In 60.0% of the cases, applications using a needle placed the injected product in endangered locations, whereas 57.1% of the cases using cannulas placed the product in endangered locations (i.e., in the vicinity of the superior/inferior labial arteries). This anatomic study revealed that injected material into the lips is frequently placed in close proximity to labial arteries representing a high risk for intra-arterial applications, leading to tissue loss (necrosis) and potential end-arterial embolism (potential blindness). Nevertheless, treatment of the lips should be a multistep approach focusing first on the far (upper and middle face) and close (labiomandibular and labiomental) perioral regions.
MeSH term(s)	Cosmetic Techniques ; Europe ; Face ; Humans ; Lip ; Middle East
Language	English
Publishing date	2019-04-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	630090-x
ISSN	1098-8793 ; 0736-6825
ISSN (online)	1098-8793
ISSN	0736-6825
DOI	10.1055/s-0039-1683856
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Article ; Online: Patient-Reported Outcomes of Split-Thickness Skin Grafts for Floor of Mouth Cancer Reconstruction.

Larson, Andrew R / Han, Mary / Webb, Katherine L / Ochoa, Edgar / Stanford-Moore, Gaelen / El-Sayed, Ivan H / George, Jonathan R / Ha, Patrick K / Heaton, Chase M / Ryan, William R

ORL; journal for oto-rhino-laryngology and its related specialties

2021 Volume 83, Issue 3, Page(s) 151–158

Abstract: Introduction: Patient-reported outcome measures (PROM) on quality of life (QOL) for early-stage floor of mouth carcinoma (FOM-CA) undergoing surgical resection and split-thickness skin graft (STSG) reconstruction have not been established. We have ... ...

Abstract	Introduction: Patient-reported outcome measures (PROM) on quality of life (QOL) for early-stage floor of mouth carcinoma (FOM-CA) undergoing surgical resection and split-thickness skin graft (STSG) reconstruction have not been established. We have performed a cross-sectional QOL analysis of such patients to define functional postoperative outcomes. Methods: Patients with pathologic stage T1/T2 FOM-CA who underwent resection and STSG reconstruction at a tertiary academic cancer center reported outcomes with the University of Washington QOL (v4) questionnaire after at least 6 months since surgery. Results: Twenty-four out of 49 eligible patients completed questionnaires with a mean follow-up of 41 months (range: 6-88). Subsites of tumor involvement/resection included the following: (1) lateral FOM (L-FOM) (n = 17), (2) anterior FOM (A-FOM) (n = 4), and (3) alveolar ridge with FOM, all of whom underwent lateral marginal mandibulectomy (MM-FOM) (n = 3). All patients reported swallowing scores of 70 ("I cannot swallow certain solid foods") or better. Ninety-six percent (23/24) reported speech of 70 ("difficulty saying some words, but I can be understood over the phone") or better. A-FOM patients reported worse chewing than L-FOM patients (mean: 50.0 vs. 85.3; p = 0.01). All 4 A-FOM patients reported a low chewing score of 50 ("I can eat soft solids but cannot chew some foods"). Otherwise, there were no significant differences between subsite groups in swallowing, speech, or taste. Conclusion: STSG reconstructions for pathologic T1-T2 FOM-CA appear to result in acceptable PROM QOL outcomes with the exception of A-FOM tumors having worse chewing outcomes.
MeSH term(s)	Cross-Sectional Studies ; Humans ; Mouth Floor ; Mouth Neoplasms/surgery ; Patient Reported Outcome Measures ; Quality of Life
Language	English
Publishing date	2021-02-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	121482-2
ISSN	1423-0275 ; 0301-1569
ISSN (online)	1423-0275
ISSN	0301-1569
DOI	10.1159/000512085
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Ul II Zs.115: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Associations of body size with all-cause and cause-specific mortality in healthy older adults.

Carr, Prudence R / Webb, Katherine L / Neumann, Johannes T / Thao, Le T P / Beilin, Lawrence J / Ernst, Michael E / Fitzgibbon, Bernadette / Gasevic, Danijela / Nelson, Mark R / Newman, Anne B / Orchard, Suzanne G / Owen, Alice / Reid, Christopher M / Stocks, Nigel P / Tonkin, Andrew M / Woods, Robyn L / McNeil, John J

Scientific reports

2023 Volume 13, Issue 1, Page(s) 3799

Abstract: In the general population, body mass index (BMI) and waist circumference are recognized risk factors for several chronic diseases and all-cause mortality. However, whether these associations are the same for older adults is less clear. The association of ...

Abstract	In the general population, body mass index (BMI) and waist circumference are recognized risk factors for several chronic diseases and all-cause mortality. However, whether these associations are the same for older adults is less clear. The association of baseline BMI and waist circumference with all-cause and cause-specific mortality was investigated in 18,209 Australian and US participants (mean age: 75.1 ± 4.5 years) from the ASPirin in Reducing Events in the Elderly (ASPREE) study, followed up for a median of 6.9 years (IQR: 5.7, 8.0). There were substantially different relationships observed in men and women. In men, the lowest risk of all-cause and cardiovascular mortality was observed with a BMI in the range 25.0-29.9 kg/m
MeSH term(s)	Aged ; Female ; Humans ; Male ; Aspirin ; Australia/epidemiology ; Body Size ; Cause of Death ; Thinness ; Waist Circumference
Chemical Substances	Aspirin (R16CO5Y76E)
Language	English
Publishing date	2023-03-07
Publishing country	England
Document type	Clinical Trial ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-29586-w
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Article ; Online: Long-Term Blood Pressure Variability and Kidney Function in Participants of the ASPREE Trial.

Ernst, Michael E / Fravel, Michelle A / Webb, Katherine L / Wetmore, James B / Wolfe, Rory / Chowdhury, Enayet / Reid, Christopher M / Woods, Robyn L / Beilin, Lawrence / Margolis, Karen L / Murray, Anne M / Polkinghorne, Kevan R

American journal of hypertension

2021 Volume 35, Issue 2, Page(s) 173–181

Abstract: Background: Whether long-term blood pressure variability (BPV) predicts kidney function decline in generally healthy older adults is unknown. We investigated this association in ASPirin in Reducing Events in the Elderly (ASPREE) trial participants.: ... ...

Abstract	Background: Whether long-term blood pressure variability (BPV) predicts kidney function decline in generally healthy older adults is unknown. We investigated this association in ASPirin in Reducing Events in the Elderly (ASPREE) trial participants. Methods: Between 2010 and 2014, Australian and US individuals aged ≥70 years (≥65 if US minority) were recruited and followed with annual study visits for a median of 4.7 years. Time-to-event analyses and linear mixed effects models were used to examine associations between incident chronic kidney disease (CKD), and trajectories of estimated glomerular filtration rate (eGFR) and log albumin-creatinine ratio (log ACR) with systolic BPV as a continuous measure, and, by tertile of SD of systolic blood pressure (BP). BPV was estimated using systolic BP measures from baseline through the second annual visit, and kidney outcomes were assessed following this period. Results: Incident CKD occurred in 1,829 of 6,759 participants (27.2%), and more commonly in BPV tertiles 2 (27.4%) and 3 (28.3%) than tertile 1 (25.5%); however, the risk was not significantly increased after covariate adjustment (tertile 3 hazard ratio = 1.02; 95% confidence interval: 0.91-1.14). Analysis of eGFR (n = 16,193) and log ACR trajectories (n = 15,213) showed individuals in the highest BPV tertile having the lowest eGFR and highest log ACR, cross-sectionally. However, the trajectories of eGFR and log ACR did not differ across BPV tertiles. Conclusions: CKD and markers of reduced kidney function occur more commonly in individuals with higher BPV; however, BPV does not influence trajectory of decline in kidney function over time in older adults who are in generally good health. Clinical trials registration: Trial Number NCT01038583 and ISRCTN83772183.
MeSH term(s)	Aged ; Aspirin/therapeutic use ; Australia/epidemiology ; Blood Pressure/physiology ; Female ; Glomerular Filtration Rate/physiology ; Humans ; Hypertension/complications ; Hypertension/diagnosis ; Hypertension/epidemiology ; Kidney ; Male ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/epidemiology
Chemical Substances	Aspirin (R16CO5Y76E)
Language	English
Publishing date	2021-09-10
Publishing country	United States
Document type	Clinical Trial ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	639383-4
ISSN	1941-7225 ; 1879-1905 ; 0895-7061
ISSN (online)	1941-7225 ; 1879-1905
ISSN	0895-7061
DOI	10.1093/ajh/hpab143
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Article ; Online: Patient-Reported Quality of Life After Resection With Primary Closure for Oral Tongue Carcinoma.

Ochoa, Edgar / Larson, Andrew R / Han, Mary / Webb, Katherine L / Stanford-Moore, Gaelen B / El-Sayed, Ivan H / George, Jonathan R / Ha, Patrick K / Heaton, Chase M / Ryan, William R

The Laryngoscope

2020 Volume 131, Issue 2, Page(s) 312–318

Abstract: Objectives/hypothesis: For early-stage oral tongue carcinoma and carcinoma in situ (ESOTCCIS), we evaluated patient-reported quality-of-life (QOL) outcomes following resection with primary closure (R-PC).: Study design: Retrospective review at an ... ...

Abstract	Objectives/hypothesis: For early-stage oral tongue carcinoma and carcinoma in situ (ESOTCCIS), we evaluated patient-reported quality-of-life (QOL) outcomes following resection with primary closure (R-PC). Study design: Retrospective review at an academic cancer center. Methods: Thirty-nine ESOTCCIS patients (Tis, T1, T2) who underwent R-PC without radiation completed the University of Washington Quality of Life Questionnaire Version 4 (UW-QOL) at least 6 months since R-PC (mean = 2.39 years; range = 0.5-6.7 years). We compared UW-QOL scores for pain, swallowing, chewing, speech, and taste to established normative population scores. Multivariable regression analysis evaluated factors associated with QOL impairment. Results: ESOTCCIS patients who underwent R-PC in comparison to the normative population reported significantly worse mean speech (87.7 vs. 98, P < .001) and taste (85.6 vs. 95, P = .002) scores and no significant differences in mean pain (91.7 vs. 86, P = .96), swallowing (100 vs. 98, P = .98), chewing (97.4 vs. 94, P = .98) scores. For speech and taste, 59% (23/39) reported no postoperative change from baseline, whereas 41% (16/39) and 35.9% (14/39) reported mild impairment, respectively. Overall, postoperative QOL was reported as good, very good, or outstanding by 87.2% (34/39). Higher American Society of Anesthesiologists class, cT1 compared to CIS, and ventral tongue involvement were independently associated with worse speech. Age < 60 years was independently associated with worse taste. Conclusions: ESOTCCIS patients who undergo R-PC without radiation can expect long-term swallowing, chewing, and pain to be in the normative range. Although a majority of patients can expect to achieve normative speech and taste outcomes, R-PC carries the risks of mild speech and/or taste impairments. Level of evidence: 4 Laryngoscope, 131:312-318, 2021.
MeSH term(s)	Academic Medical Centers ; Adult ; Aged ; Carcinoma in Situ/physiopathology ; Carcinoma in Situ/psychology ; Carcinoma in Situ/surgery ; Carcinoma, Squamous Cell/physiopathology ; Carcinoma, Squamous Cell/psychology ; Carcinoma, Squamous Cell/surgery ; Deglutition ; Female ; Humans ; Male ; Mastication ; Middle Aged ; Oral Surgical Procedures/methods ; Oral Surgical Procedures/psychology ; Pain Measurement ; Patient Reported Outcome Measures ; Postoperative Period ; Quality of Life ; Regression Analysis ; Retrospective Studies ; Severity of Illness Index ; Speech ; Surveys and Questionnaires ; Taste ; Tongue Neoplasms/physiopathology ; Tongue Neoplasms/psychology ; Tongue Neoplasms/surgery ; Treatment Outcome
Language	English
Publishing date	2020-05-07
Publishing country	United States
Document type	Evaluation Study ; Journal Article
ZDB-ID	80180-x
ISSN	1531-4995 ; 0023-852X
ISSN (online)	1531-4995
ISSN	0023-852X
DOI	10.1002/lary.28723
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Article: Treating the Lips and Its Anatomical Correlate in Respect to Vascular Compromise

Ghannam, Sahar / Sattler, Sonja / Frank, Konstantin / Freytag, David L. / Webb, Katherine L. / Devineni, Aditya / Cotofana, Sebastian

Facial Plastic Surgery

(Aesthetic Treatment of the Jawline and Perioral Area)

2019 Volume 35, Issue 02, Page(s) 193–203

Series title	Aesthetic Treatment of the Jawline and Perioral Area
Abstract	Treating the lips to increase facial attractiveness and youthfulness is challenging when trying to consider ethnic differences in an increasingly more diverse society. Multiple injection techniques are currently available for treating lip contour and volume, but a validation in the cadaveric model under the aspects of safety has not been performed yet. The injection techniques presented in this study are based on the experience and personal selection of the authors. The authors have assessed, treated, and evaluated for more than 20 years patients from the Middle East and Central Europe. Cadaveric verification was performed for each of the presented techniques to identify the positioning of the injected product inside the lips and its relation to the superior/inferior labial arteries. The results of the anatomic analyses revealed that in 58.3% of the performed injections, the product was placed close to the superior/inferior labial arteries. In 60.0% of the cases, applications using a needle placed the injected product in endangered locations, whereas 57.1% of the cases using cannulas placed the product in endangered locations (i.e., in the vicinity of the superior/inferior labial arteries). This anatomic study revealed that injected material into the lips is frequently placed in close proximity to labial arteries representing a high risk for intra-arterial applications, leading to tissue loss (necrosis) and potential end-arterial embolism (potential blindness). Nevertheless, treatment of the lips should be a multistep approach focusing first on the far (upper and middle face) and close (labiomandibular and labiomental) perioral regions.
Keywords	lips ; contouring ; volumizing ; labial arteries ; danger zone
Language	English
Publishing date	2019-04-01
Publisher	Thieme Medical Publishers
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	630090-x
ISSN	1098-8793 ; 0736-6825
ISSN (online)	1098-8793
ISSN	0736-6825
DOI	10.1055/s-0039-1683856
Database	Thieme publisher's database

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In stock of ZB MED Cologne/Königswinter

Order via subito