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  1. Article: Purpura Hemorrhagica Treated with Antistreptococcus Serum; Recovery.

    Webber, L R

    The Journal of comparative medicine and veterinary archives

    2022  Volume 19, Issue 6, Page(s) 398–399

    Language English
    Publishing date 2022-10-24
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Clinician awareness of the risk of anaphylaxis in patients with cutaneous mastocytosis.

    Vincent, Rosie / Webber, Lucy / Dunnill, Michael Giles S

    Clinical and experimental dermatology

    2023  Volume 48, Issue 11, Page(s) 1271–1272

    MeSH term(s) Humans ; Anaphylaxis/etiology ; Mastocytosis, Cutaneous/complications ; Mastocytosis, Cutaneous/diagnosis ; Mastocytosis ; Mast Cells ; Mastocytosis, Systemic
    Language English
    Publishing date 2023-07-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 195504-4
    ISSN 1365-2230 ; 0307-6938
    ISSN (online) 1365-2230
    ISSN 0307-6938
    DOI 10.1093/ced/llad237
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A case of multiple self-healing squamous epitheliomas of Ferguson-Smith in a patient on systemic immunosuppression for rheumatoid arthritis.

    Prideaux, Amy / Davidson, Leonie / Webber, Lucy / Hitchens, Emma / Keith, Daniel

    Clinical and experimental dermatology

    2023  Volume 48, Issue 12, Page(s) 1388–1390

    MeSH term(s) Humans ; Carcinoma, Squamous Cell ; Keratoacanthoma ; Immunosuppression Therapy/adverse effects ; Arthritis, Rheumatoid/drug therapy ; Skin Neoplasms ; Carcinoma
    Language English
    Publishing date 2023-08-23
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 195504-4
    ISSN 1365-2230 ; 0307-6938
    ISSN (online) 1365-2230
    ISSN 0307-6938
    DOI 10.1093/ced/llad290
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The COVID-19 hangover: why we need to take harm caused by alcohol seriously as an indirect effect of the pandemic.

    Boniface, Sadie / Card-Gowers, Joshua / Webber, Laura

    British journal of hospital medicine (London, England : 2005)

    2022  Volume 83, Issue 10, Page(s) 1–3

    Abstract: In the UK, harm caused by alcohol has worsened since 2020. A recent report from the Institute of Alcohol Studies projecting future rates of major alcohol-related diseases highlights what this means for health and healthcare. The authors argue that this ... ...

    Abstract In the UK, harm caused by alcohol has worsened since 2020. A recent report from the Institute of Alcohol Studies projecting future rates of major alcohol-related diseases highlights what this means for health and healthcare. The authors argue that this additional burden is not inevitable if effective policies are introduced.
    MeSH term(s) Humans ; Pandemics/prevention & control ; COVID-19 ; Alcohol Drinking/adverse effects ; Alcohol Drinking/epidemiology ; Alcoholic Intoxication/epidemiology ; Ethanol
    Chemical Substances Ethanol (3K9958V90M)
    Language English
    Publishing date 2022-10-20
    Publishing country England
    Document type Editorial
    ISSN 1750-8460
    ISSN 1750-8460
    DOI 10.12968/hmed.2022.0384
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Projected incidence of overweight and obesity and related disease incidence across Poland.

    Webber, Laura

    Central European journal of public health

    2014  Volume 22, Issue 1, Page(s) 17–23

    Abstract: The first objective is to project obesity trends to 2030 based on the current data from Poland. The second objective is to test the effect of a 1% or 5% decrease in population BMI upon future incidence and prevalence of related non-communicable diseases. ...

    Abstract The first objective is to project obesity trends to 2030 based on the current data from Poland. The second objective is to test the effect of a 1% or 5% decrease in population BMI upon future incidence and prevalence of related non-communicable diseases. A two-stage modelling design projecting overweight and obesity trends and related diseases in a microsimulation model was developed. Epidemiological data for entry into a microsimulation model were gathered from Poland. This study used population level data from Poland creating a virtual population within a microsimulation model. Obesity and overweight in Poland was found to increase to very high levels in men while trends remained unchanged in women. In a country that currently has about 38 million inhabitants, it is anticipated that by 2030, there might be more than 9 million new cancer cases; 10 million CHD and stroke cases, and 7 million new cases of type 2 diabetes. These findings have policy implications highlighting the need for action to curb trends and to reduce increases in the rates of diet-related non-communicable disease.
    MeSH term(s) Adolescent ; Adult ; Aged ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; Comorbidity ; Computer Simulation ; Diabetes Mellitus/epidemiology ; Diabetes Mellitus/etiology ; Female ; Forecasting/methods ; Humans ; Incidence ; Male ; Middle Aged ; Neoplasms/epidemiology ; Neoplasms/etiology ; Obesity/complications ; Obesity/epidemiology ; Overweight/complications ; Overweight/epidemiology ; Poland/epidemiology ; Prevalence ; Sex Distribution ; Young Adult
    Language English
    Publishing date 2014-03
    Publishing country Czech Republic
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1176053-9
    ISSN 1803-1048 ; 1210-7778 ; 0022-1732
    ISSN (online) 1803-1048
    ISSN 1210-7778 ; 0022-1732
    DOI 10.21101/cejph.a3877
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Impact of COVID-19 vaccination on COVID-19 hospital admissions in England during 2021: an observational study.

    Cornforth, Felicity / Webber, Lucie / Kerr, Gabriele / Dinsdale, Hywell / Majeed, Azeem / Greengross, Peter

    Journal of the Royal Society of Medicine

    2023  Volume 116, Issue 5, Page(s) 167–176

    Abstract: Objectives: To examine the impact of COVID-19 vaccination on hospital admissions in England in 2021.: Design: Observational study of emergency admissions for COVID-19 by vaccination status in people 16 years and over in England.: Setting: ... ...

    Abstract Objectives: To examine the impact of COVID-19 vaccination on hospital admissions in England in 2021.
    Design: Observational study of emergency admissions for COVID-19 by vaccination status in people 16 years and over in England.
    Setting: Hospitals in England.
    Participants: A total of 48.1 million people registered with an English GP, aged ≥16 years with a recent NHS contact.
    Main outcome measures: Emergency hospital admissions with a primary diagnosis of COVID-19 between 1 January and 31 December 2021. Monthly admission rates were directly standardised for age, sex, risk category and vaccination dose to estimate vaccine effectiveness (VE) over time, between vaccine doses, age groups and risk groups.
    Results: A total of 192,047 hospital admissions were included. The unvaccinated admission rate was higher in December 2021 (6.1 admissions per 100,000 person-days; 95% CI: 5.9 to 6.3) than January 2021 (4.9; 95% CI: 4.9 to 5.0). Vaccinated admission rates were ≤1 per 100,000 from February to December. Doses 1 and 2 VE waned over time, particularly in older and clinically vulnerable groups (although this may reflect that they were vaccinated earlier). Dose 3 VE remained above 93%.
    Conclusions: COVID-19 hospitalisations were consistently highest in the unvaccinated. Despite high case rates at the end of 2021, overall admission rates remained stable, driven by low admission rates among vaccinated people. There is population-level waning in VE, recovering after subsequent doses, potentially more marked in older and at-risk groups. The findings support JCVI (Joint Committee on Vaccination and Immunisation) guidance for an ongoing booster programme, especially in older people and higher clinical risk groups.
    MeSH term(s) Humans ; Aged ; COVID-19 Vaccines ; COVID-19/epidemiology ; COVID-19/prevention & control ; Hospitalization ; England/epidemiology ; Vaccination ; Hospitals
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-02-24
    Publishing country England
    Document type Observational Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 6731-3
    ISSN 1758-1095 ; 0141-0768 ; 0035-9157
    ISSN (online) 1758-1095
    ISSN 0141-0768 ; 0035-9157
    DOI 10.1177/01410768231157017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Characterization of dorsal recumbency syndrome associated with woody breast in broiler flocks from Ontario, Canada

    Che, Sunoh / Webber, L. / Novy, Anastasia / Barbut, Shai / Susta, Leonardo

    Poultry Science. 2023 Feb., v. 102, no. 2, p. 102307

    2022  , Page(s) 102307

    Abstract: A dorsal recumbency syndrome (DRS) has been recently described in market-age broiler chickens. Affected broilers fall onto their backs, and are unable to right themselves, and eventually die of cardiopulmonary insufficiency. These broilers are referred ... ...

    Abstract A dorsal recumbency syndrome (DRS) has been recently described in market-age broiler chickens. Affected broilers fall onto their backs, and are unable to right themselves, and eventually die of cardiopulmonary insufficiency. These broilers are referred to as turtle chickens. A previous report and anecdotal evidence suggest that breast myopathies, such as woody breast (WB), may be associated with DRS due to impaired contractility of the pectoral muscles. In this study, we aimed to provide additional evidence to document DRS in broilers, and its possible association with breast myopathies. A total of 64 broilers (Ross 708), 33 DRS-affected and 31 controls, were culled between 42 and 48 d of age from 3 different commercial farms over 4 visits. All broilers underwent postmortem analysis; breast muscles were scored grossly and/or histologically to determine the presence and severity of myopathies, and sera were used to determine the level of aspartate aminotransferase (AST) and creatine kinase (CK). A gross diagnosis of WB was moderately associated with DRS broilers, and DRS broilers displayed a greater microscopic severity of lesions (P < 0.001) in the Pectoralis major, as typically observed with WB. Levels of AST and CK were greater (P < 0.001) in the sera of DRS-affected compared to control broilers, consistent with muscular damage. The frequency of cardiac changes, such as mild hydropericardium and right ventricular dilation, or severity of microscopic pulmonary lesions, such as edema, were not significantly different between the 2 groups. The odds of DRS increased with the histology score of the P. major (OR = 1.37, 95% CI 1.02-1.85). The data presented in this study support an association between DRS and muscular damage of the P. major, suggesting that WB may predispose broilers to DRS. DRS might be a cause of broiler death, and this syndrome could be responsible for significant financial loss to the farmers and to the whole poultry industry.
    Keywords aspartate transaminase ; breasts ; creatine kinase ; death ; edema ; financial economics ; histology ; pectoralis muscle ; poultry industry ; turtles ; wooden breast ; Ontario ; broiler chicken ; meat quality ; myopathy ; serum chemistry ; turtle bird
    Language English
    Dates of publication 2022-1030
    Size p. 102307
    Publishing place Elsevier Inc.
    Document type Article ; Online
    Note Pre-press version ; Use and reproduction
    ZDB-ID 242586-5
    ISSN 1525-3171 ; 0032-5791
    ISSN (online) 1525-3171
    ISSN 0032-5791
    DOI 10.1016/j.psj.2022.102307
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Fragrance exposure in the U.K.: has there been a change in the last decade?

    Webber, L / Keith, D / Walker-Smith, P / Buckley, D A

    The British journal of dermatology

    2018  Volume 179, Issue 5, Page(s) 1199–1200

    MeSH term(s) Allergens/adverse effects ; Dermatitis, Allergic Contact/diagnosis ; Dermatitis, Allergic Contact/etiology ; Dermatitis, Allergic Contact/prevention & control ; Humans ; Odorants ; Patch Tests ; Perfume/adverse effects ; Product Labeling/standards ; Product Labeling/statistics & numerical data ; United Kingdom
    Chemical Substances Allergens ; Perfume
    Language English
    Publishing date 2018-09-05
    Publishing country England
    Document type Letter
    ZDB-ID 80076-4
    ISSN 1365-2133 ; 0007-0963
    ISSN (online) 1365-2133
    ISSN 0007-0963
    DOI 10.1111/bjd.16914
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book: The cinema of urban crisis

    Webber, Lawrence

    seventies film and the reinvention of the city

    (Cities and Cultures)

    2014  

    Author's details Lawrence Webb
    Series title Cities and Cultures
    Keywords Cities and towns in motion pictures ; City and town life in motion pictures ; Motion pictures/History ; Motion pictures/Social aspects
    Language English
    Size 423 pages, illustrations, 24 cm
    Publisher Amsterdam University Press
    Publishing place Amsterdam
    Document type Book
    ISBN 908964637X ; 9789048522996 ; 9789089646378 ; 9048522994
    Database Former special subject collection: coastal and deep sea fishing

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  10. Article ; Online: DICE: Dual mTorc Inhibition in advanCed/recurrent Epithelial ovarian cancer resistant to standard treatment-a study protocol for a randomised trial investigating a novel therapy called TAK228.

    Fiorentino, Francesca / Krell, Jonathan / de la Rosa, Consuelo Nohpal / Webber, Lee

    Trials

    2022  Volume 23, Issue 1, Page(s) 261

    Abstract: Background: The standard initial treatment for ovarian cancer is surgery and platinum-based chemotherapy and potentially maintenance therapy with avastin or inhibitors of poly-ADP ribose polymerase (PARP). While a proportion of women are cured by this ... ...

    Abstract Background: The standard initial treatment for ovarian cancer is surgery and platinum-based chemotherapy and potentially maintenance therapy with avastin or inhibitors of poly-ADP ribose polymerase (PARP). While a proportion of women are cured by this approach, the vast majority will relapse and become resistant to platinum chemotherapy either initially or on subsequent treatment. There is an unmet need to improve response to treatment and quality of life in these women. TAK228 is a novel therapy that can be added to standard treatment in the participant population and the aim of the DICE trial is to assess its effectiveness. Laboratory and clinical research has shown that these ovarian cancers may respond to the molecular target of a drug such as TAK228, and there have been studies using it in other advanced solid tumours including endometrial cancer.
    Methods: One hundred twenty-four eligible women will be recruited from participating research sites in the United Kingdom (UK) and Germany. Randomised participants will receive either weekly paclitaxel alone (standard treatment, n = 62) or TAK228 plus weekly paclitaxel (n = 62) until the cancer significantly worsens; there are significant adverse events or any other protocol-defined stopping criteria. Participants will be monitored for response to treatment (using radiological imaging), adverse events and quality of life during both randomised treatment and subsequent follow-up.
    Discussion: The primary objective/endpoint of the study is to compare the two treatments in terms of progression-free survival, or the length of time that each participant is alive without the cancer significantly worsening according to defined assessment criteria. If the addition of TAK228 to weekly paclitaxel chemotherapy is shown to significantly improve this statistically, and adverse events and quality of life are not significantly worse than standard treatment, then TAK228 plus weekly paclitaxel could potentially be taken forward within the context of a larger phase III trial.
    Trial registration: ClinicalTrials.gov NCT03648489 . Registered on 27 August 2018.
    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Carcinoma, Ovarian Epithelial/drug therapy ; Female ; Humans ; Neoplasm Recurrence, Local/drug therapy ; Ovarian Neoplasms/drug therapy ; Paclitaxel/adverse effects ; Quality of Life
    Chemical Substances Paclitaxel (P88XT4IS4D)
    Language English
    Publishing date 2022-04-05
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1745-6215
    ISSN (online) 1745-6215
    ISSN 1468-6694 ; 1745-6215
    DOI 10.1186/s13063-022-06201-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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