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  1. Article: Shifted levels of sleep and activity under darkness as mechanisms underlying ectoparasite resistance.

    Benoit, Joshua B / Ajayi, Oluwaseun M / Webster, Ashley / Grieshop, Karl / Lewis, David / Talbott, Hailie / Bose, Joy / Polak, Michal

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Parasites harm host fitness and are pervasive agents of natural selection. Host defensive traits in natural populations typically show genetic variation, which may be maintained when parasite resistance imposes fitness costs on the host coupled with ... ...

    Abstract Parasites harm host fitness and are pervasive agents of natural selection. Host defensive traits in natural populations typically show genetic variation, which may be maintained when parasite resistance imposes fitness costs on the host coupled with variability in parasite prevalence in space and/or time. Previously we demonstrated significant evolutionary responses to artificial selection for increasing behavioral immunity to
    Language English
    Publishing date 2023-11-02
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.10.30.564749
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ovary abortion is prevalent in diverse maize inbred lines and is under genetic control.

    Gustin, Jeffery L / Boehlein, Susan K / Shaw, Janine R / Junior, Weschester / Settles, A Mark / Webster, Ashley / Tracy, William F / Hannah, L Curtis

    Scientific reports

    2018  Volume 8, Issue 1, Page(s) 13032

    Abstract: Crop improvement programs focus on characteristics that are important for plant productivity. Typically genes underlying these traits are identified and stacked to create improved cultivars. Hence, identification of valuable traits for plant productivity ...

    Abstract Crop improvement programs focus on characteristics that are important for plant productivity. Typically genes underlying these traits are identified and stacked to create improved cultivars. Hence, identification of valuable traits for plant productivity is critical for plant improvement. Here we describe an important characteristic for maize productivity. Despite the fact mature maize ears are typically covered with kernels, we find that only a fraction of ovaries give rise to mature kernels. Non-developed ovaries degenerate while neighboring fertilized ovaries produce kernels that fill the ear. Abortion occurs throughout the ear, not just at the tip. We show that the fraction of aborted ovaries/kernels is genetically controlled and varies widely among maize lines, and low abortion genotypes are rare. Reducing or eliminating ovary abortion could substantially increase yield, making this characteristic a new target for selection in maize improvement programs.
    MeSH term(s) Flowers/physiology ; Gene Expression Regulation, Plant ; Inbreeding ; Reproduction ; Zea mays/genetics ; Zea mays/physiology
    Language English
    Publishing date 2018-08-29
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-018-31216-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effects of long-term exposure to elevated temperature on Zea mays endosperm development during grain fill.

    Boehlein, Susan K / Liu, Peng / Webster, Ashley / Ribeiro, Camila / Suzuki, Masaharu / Wu, Shan / Guan, Jiahn-Chou / Stewart, Jon D / Tracy, William F / Settles, A Mark / McCarty, Donald R / Koch, Karen E / Hannah, Larkin C / Hennen-Bierwagen, Tracie A / Myers, Alan M

    The Plant journal : for cell and molecular biology

    2019  Volume 99, Issue 1, Page(s) 23–40

    Abstract: Cereal yields decrease when grain fill proceeds under conditions of prolonged, moderately elevated temperatures. Endosperm-endogenous processes alter both rate and duration of dry weight gain, but underlying mechanisms remain unclear. Heat effects could ... ...

    Abstract Cereal yields decrease when grain fill proceeds under conditions of prolonged, moderately elevated temperatures. Endosperm-endogenous processes alter both rate and duration of dry weight gain, but underlying mechanisms remain unclear. Heat effects could be mediated by either abnormal, premature cessation of storage compound deposition or accelerated implementation of normal development. This study used controlled environments to isolate temperature as the sole environmental variable during Zea mays kernel-fill, from 12 days after pollination to maturity. Plants subjected to elevated day, elevated night temperatures (38°C day, 28°C night (38/28°C])) or elevated day, normal night (38/17°C), were compared with those from controls grown under normal day and night conditions (28/17°C). Progression of change over time in endosperm tissue was followed to dissect contributions at multiple levels, including transcriptome, metabolome, enzyme activities, product accumulation, and tissue ultrastructure. Integrated analyses indicated that the normal developmental program of endosperm is fully executed under prolonged high-temperature conditions, but at a faster rate. Accelerated development was observed when both day and night temperatures were elevated, but not when daytime temperature alone was increased. Although transcripts for most components of glycolysis and respiration were either upregulated or minimally affected, elevated temperatures decreased abundance of mRNAs related to biosynthesis of starch and storage proteins. Further analysis of 20 central-metabolic enzymes revealed six activities that were reduced under high-temperature conditions, indicating candidate roles in the observed reduction of grain dry weight. Nonetheless, a striking overall resilience of grain filling in the face of elevated temperatures can be attributed to acceleration of normal endosperm development.
    MeSH term(s) Edible Grain/genetics ; Edible Grain/metabolism ; Edible Grain/physiology ; Endosperm/genetics ; Endosperm/metabolism ; Endosperm/physiology ; RNA, Messenger/metabolism ; RNA, Plant/metabolism ; Temperature ; Zea mays/genetics ; Zea mays/metabolism ; Zea mays/physiology
    Chemical Substances RNA, Messenger ; RNA, Plant
    Language English
    Publishing date 2019-03-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1088037-9
    ISSN 1365-313X ; 0960-7412
    ISSN (online) 1365-313X
    ISSN 0960-7412
    DOI 10.1111/tpj.14283
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 6071: Show issues

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  4. Article: Effects of long‐term exposure to elevated temperature on Zea mays endosperm development during grain fill

    Boehlein, Susan K / Guan, Jiahn‐Chou / Hannah, Larkin C / Hennen‐Bierwagen, Tracie A / Koch, Karen E / Liu, Peng / McCarty, Donald R / Myers, Alan M / Ribeiro, Camila / Settles, A. Mark / Stewart, Jon D / Suzuki, Masaharu / Tracy, William F / Webster, Ashley / Wu, Shan

    plant journal. 2019 July, v. 99, no. 1

    2019  

    Abstract: Cereal yields decrease when grain fill proceeds under conditions of prolonged, moderately elevated temperatures. Endosperm‐endogenous processes alter both rate and duration of dry weight gain, but underlying mechanisms remain unclear. Heat effects could ... ...

    Abstract Cereal yields decrease when grain fill proceeds under conditions of prolonged, moderately elevated temperatures. Endosperm‐endogenous processes alter both rate and duration of dry weight gain, but underlying mechanisms remain unclear. Heat effects could be mediated by either abnormal, premature cessation of storage compound deposition or accelerated implementation of normal development. This study used controlled environments to isolate temperature as the sole environmental variable during Zea mays kernel‐fill, from 12 days after pollination to maturity. Plants subjected to elevated day, elevated night temperatures (38°C day, 28°C night (38/28°C])) or elevated day, normal night (38/17°C), were compared with those from controls grown under normal day and night conditions (28/17°C). Progression of change over time in endosperm tissue was followed to dissect contributions at multiple levels, including transcriptome, metabolome, enzyme activities, product accumulation, and tissue ultrastructure. Integrated analyses indicated that the normal developmental program of endosperm is fully executed under prolonged high‐temperature conditions, but at a faster rate. Accelerated development was observed when both day and night temperatures were elevated, but not when daytime temperature alone was increased. Although transcripts for most components of glycolysis and respiration were either upregulated or minimally affected, elevated temperatures decreased abundance of mRNAs related to biosynthesis of starch and storage proteins. Further analysis of 20 central‐metabolic enzymes revealed six activities that were reduced under high‐temperature conditions, indicating candidate roles in the observed reduction of grain dry weight. Nonetheless, a striking overall resilience of grain filling in the face of elevated temperatures can be attributed to acceleration of normal endosperm development.
    Keywords biosynthesis ; chronic exposure ; endosperm ; enzyme activity ; enzymes ; filling period ; gene expression regulation ; glycolysis ; heat ; messenger RNA ; metabolome ; night temperature ; pollination ; starch ; storage proteins ; transcriptome ; ultrastructure ; weight gain ; Zea mays
    Language English
    Dates of publication 2019-07
    Size p. 23-40.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 1088037-9
    ISSN 1365-313X ; 0960-7412
    ISSN (online) 1365-313X
    ISSN 0960-7412
    DOI 10.1111/tpj.14283
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 6071: Show issues

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  5. Article ; Online: Risk of Surgical Site Infection (SSI) following Colorectal Resection Is Higher in Patients With Disseminated Cancer: An NCCN Member Cohort Study.

    Kamboj, Mini / Childers, Teresa / Sugalski, Jessica / Antonelli, Donna / Bingener-Casey, Juliane / Cannon, Jamie / Cluff, Karie / Davis, Kimberly A / Dellinger, E Patchen / Dowdy, Sean C / Duncan, Kim / Fedderson, Julie / Glasgow, Robert / Hall, Bruce / Hirsch, Marilyn / Hutter, Matthew / Kimbro, Lisa / Kuvshinoff, Boris / Makary, Martin /
    Morris, Melanie / Nehring, Sharon / Ramamoorthy, Sonia / Scott, Rebekah / Sovel, Mindy / Strong, Vivian / Webster, Ashley / Wick, Elizabeth / Aguilar, Julio Garcia / Carlson, Robert / Sepkowitz, Kent

    Infection control and hospital epidemiology

    2018  Volume 39, Issue 5, Page(s) 555–562

    Abstract: BACKGROUNDSurgical site infections (SSIs) following colorectal surgery (CRS) are among the most common healthcare-associated infections (HAIs). Reduction in colorectal SSI rates is an important goal for surgical quality improvement.OBJECTIVETo examine ... ...

    Abstract BACKGROUNDSurgical site infections (SSIs) following colorectal surgery (CRS) are among the most common healthcare-associated infections (HAIs). Reduction in colorectal SSI rates is an important goal for surgical quality improvement.OBJECTIVETo examine rates of SSI in patients with and without cancer and to identify potential predictors of SSI risk following CRSDESIGNAmerican College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) data files for 2011-2013 from a sample of 12 National Comprehensive Cancer Network (NCCN) member institutions were combined. Pooled SSI rates for colorectal procedures were calculated and risk was evaluated. The independent importance of potential risk factors was assessed using logistic regression.SETTINGMulticenter studyPARTICIPANTSOf 22 invited NCCN centers, 11 participated (50%). Colorectal procedures were selected by principal procedure current procedural technology (CPT) code. Cancer was defined by International Classification of Disease, Ninth Revision, Clinical Modification (ICD-9-CM) codes.MAIN OUTCOMEThe primary outcome of interest was 30-day SSI rate.RESULTSA total of 652 SSIs (11.06%) were reported among 5,893 CRSs. Risk of SSI was similar for patients with and without cancer. Among CRS patients with underlying cancer, disseminated cancer (SSI rate, 17.5%; odds ratio [OR], 1.66; 95% confidence interval [CI], 1.23-2.26; P=.001), ASA score ≥3 (OR, 1.41; 95% CI, 1.09-1.83; P=.001), chronic obstructive pulmonary disease (COPD; OR, 1.6; 95% CI, 1.06-2.53; P=.02), and longer duration of procedure were associated with development of SSI.CONCLUSIONSPatients with disseminated cancer are at a higher risk for developing SSI. ASA score >3, COPD, and longer duration of surgery predict SSI risk. Disseminated cancer should be further evaluated by the Centers for Disease Control and Prevention (CDC) in generating risk-adjusted outcomes.Infect Control Hosp Epidemiol 2018;39:555-562.
    MeSH term(s) Adult ; Aged ; Cohort Studies ; Colorectal Neoplasms/epidemiology ; Colorectal Neoplasms/surgery ; Databases, Factual ; Digestive System Surgical Procedures/adverse effects ; Female ; Humans ; Logistic Models ; Male ; Middle Aged ; Rectum/surgery ; Risk Factors ; Surgical Wound Infection/epidemiology ; Surgical Wound Infection/etiology ; United States/epidemiology
    Language English
    Publishing date 2018-03-19
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2018.40
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1714: Show issues Location:
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