Article: Guanylyl cyclases: approaching year thirty.
Trends in endocrinology and metabolism: TEM
2008 Volume 9, Issue 6, Page(s) 213–219
Abstract: Since its discovery in 1963, cyclic GMP (cGMP) has been shown to be a ubiquitous second messenger. The enzymes that catalyze the formation of cGMP from GTP, guanylyl cyclases, exist in soluble and particulate isoforms. An explosion in the number of known ...
Abstract | Since its discovery in 1963, cyclic GMP (cGMP) has been shown to be a ubiquitous second messenger. The enzymes that catalyze the formation of cGMP from GTP, guanylyl cyclases, exist in soluble and particulate isoforms. An explosion in the number of known isoforms, gene disruption, identification of new inhibitors and activators and finally the resolution of the structure of adenylyl cyclases have all provided important clues about the structure and function of guanylyl cyclases. This article gives a brief review of the recent developments in the field of guanylyl cyclase research. |
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Language | English |
Publishing date | 2008-01-31 |
Publishing country | United States |
Document type | Journal Article |
ZDB-ID | 1042384-9 |
ISSN | 1879-3061 ; 1043-2760 |
ISSN (online) | 1879-3061 |
ISSN | 1043-2760 |
DOI | 10.1016/s1043-2760(98)00061-7 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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