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  1. Article ; Online: Differences in presentation of cutaneous melanoma among Asian American and Pacific Islander patients.

    Wei, Angela H / Fane, Lauren S / Tripathi, Raghav / Bordeaux, Jeremy S

    Journal of the American Academy of Dermatology

    2023  Volume 90, Issue 2, Page(s) 380–382

    MeSH term(s) Humans ; Melanoma ; Skin Neoplasms ; Asian ; Melanoma, Cutaneous Malignant ; Pacific Island People
    Language English
    Publishing date 2023-09-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2023.09.051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Disparities between Asian groups in time to melanoma treatment: A cross-sectional study.

    Fane, Lauren S / Wei, Angela H / Tripathi, Raghav / Bordeaux, Jeremy S

    Journal of the American Academy of Dermatology

    2023  Volume 89, Issue 2, Page(s) 392–394

    MeSH term(s) Humans ; Cross-Sectional Studies ; Ethnicity ; Healthcare Disparities/ethnology ; Hispanic or Latino ; Melanoma/ethnology ; Melanoma/therapy ; United States ; Asian/ethnology ; Time-to-Treatment
    Language English
    Publishing date 2023-04-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2023.03.053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Asian American and Pacific Islander patients with melanoma have increased odds of treatment delays: A cross-sectional study.

    Fane, Lauren S / Wei, Angela H / Tripathi, Raghav / Bordeaux, Jeremy S

    Journal of the American Academy of Dermatology

    2023  Volume 89, Issue 3, Page(s) 529–536

    Abstract: Background: Asian American and Pacific Islander (AAPI) melanoma patients have higher mortality than non-Hispanic White (NHW) patients. Treatment delays may contribute, but whether AAPI patients have longer time from diagnosis to definitive surgery (TTDS) ...

    Abstract Background: Asian American and Pacific Islander (AAPI) melanoma patients have higher mortality than non-Hispanic White (NHW) patients. Treatment delays may contribute, but whether AAPI patients have longer time from diagnosis to definitive surgery (TTDS) is unknown.
    Objectives: Investigate TTDS differences between AAPI and NHW melanoma patients.
    Methods: Retrospective review of AAPI and NHW melanoma patients in the National Cancer Database (NCD) (2004-2020). The association of race with TTDS was evaluated by multivariable logistic regression, controlling for sociodemographic characteristics.
    Results: Of 354,943 AAPI and NHW melanoma patients identified, 1155 (0.33%) were AAPI. AAPI patients had longer TTDS for stage I, II, and III melanoma (P < .05 for all). Adjusting for sociodemographic factors, AAPI patients had 1.5 times the odds of a TTDS between 61 and 90 days and twice the odds of a TTDS >90 days. Racial differences in TTDS persisted in Medicare and private insurance types. Uninsured AAPI patients had the longest TTDS (mean, 53.26 days), while those with private insurance had the shortest TTDS (mean, 34.92 days; P < .001 for both).
    Limitation: AAPI patients comprised 0.33% of the sample.
    Conclusions: AAPI melanoma patients have increased odds of treatment delays. Associated socioeconomic differences should inform efforts to reduce disparities in treatment and survival.
    MeSH term(s) Aged ; Humans ; Asian/statistics & numerical data ; Cross-Sectional Studies ; Medicare/statistics & numerical data ; Melanoma/epidemiology ; Melanoma/ethnology ; Melanoma/therapy ; Pacific Island People ; Time-to-Treatment ; United States/epidemiology ; Skin Neoplasms/epidemiology ; Skin Neoplasms/ethnology ; Skin Neoplasms/therapy ; Health Services Accessibility/statistics & numerical data
    Language English
    Publishing date 2023-05-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2023.05.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Incidence and characteristics of acral lentiginous melanoma in Asian Americans and Pacific Islanders.

    Wei, Angela H / Zheng, David X / Cullison, Christopher R / Scott, Jeffrey F / Carroll, Bryan T

    Journal of the American Academy of Dermatology

    2023  Volume 90, Issue 2, Page(s) 374–376

    MeSH term(s) Humans ; Incidence ; Melanoma/epidemiology ; Melanoma/ethnology ; Melanoma, Cutaneous Malignant ; Skin Neoplasms/epidemiology ; Asian American Native Hawaiian and Pacific Islander/statistics & numerical data ; United States/epidemiology
    Language English
    Publishing date 2023-09-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2023.09.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Abnormal thrombosis and neutrophil activation increase hospital-acquired sacral pressure injuries and morbidity in COVID-19 patients.

    Narang, Jatin / Jatana, Samreen / Ponti, András K / Musich, Ryan / Gallop, Joshua / Wei, Angela H / Seck, Sokhna / Johnson, Jessica / Kokoczka, Lynne / Nowacki, Amy S / McBride, Jeffrey D / Mireles-Cabodevila, Eduardo / Gordon, Steven / Cooper, Kevin / Fernandez, Anthony P / McDonald, Christine

    Frontiers in immunology

    2023  Volume 14, Page(s) 1031336

    Abstract: Hospitalized patients have an increased risk of developing hospital-acquired sacral pressure injury (HASPI). However, it is unknown whether SARS-CoV-2 infection affects HASPI development. To explore the role of SARS-CoV-2 infection in HASPI development, ... ...

    Abstract Hospitalized patients have an increased risk of developing hospital-acquired sacral pressure injury (HASPI). However, it is unknown whether SARS-CoV-2 infection affects HASPI development. To explore the role of SARS-CoV-2 infection in HASPI development, we conducted a single institution, multi-hospital, retrospective study of all patients hospitalized for ≥5 days from March 1, 2020 to December 31, 2020. Patient demographics, hospitalization information, ulcer characteristics, and 30-day-related morbidity were collected for all patients with HASPIs, and intact skin was collected from HASPI borders in a patient subset. We determined the incidence, disease course, and short-term morbidity of HASPIs in COVID-19(+) patients, and characterized the skin histopathology and tissue gene signatures associated with HASPIs in COVID-19 disease. COVID-19(+) patients had a 63% increased HASPI incidence rate, HASPIs of more severe ulcer stage (OR 2.0, p<0.001), and HASPIs more likely to require debridement (OR 3.1, p=0.04) compared to COVID-19(-) patients. Furthermore, COVID-19(+) patients with HASPIs had 2.2x increased odds of a more severe hospitalization course compared to COVID-19(+) patients without HASPIs. HASPI skin histology from COVID-19(+) patients predominantly showed thrombotic vasculopathy, with the number of thrombosed vessels being significantly greater than HASPIs from COVID-19(-) patients. Transcriptional signatures of a COVID-19(+) sample subset were enriched for innate immune responses, thrombosis, and neutrophil activation genes. Overall, our results suggest that immunologic dysregulation secondary to SARS-CoV-2 infection, including neutrophil dysfunction and abnormal thrombosis, may play a pathogenic role in development of HASPIs in patients with severe COVID-19.
    MeSH term(s) Humans ; COVID-19/epidemiology ; Pressure Ulcer/epidemiology ; SARS-CoV-2 ; Retrospective Studies ; Ulcer ; Neutrophil Activation ; Incidence ; Thrombosis/epidemiology ; Thrombosis/etiology ; Hospitals
    Language English
    Publishing date 2023-03-21
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1031336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Trends of Research Output of Allopathic Medical Students Matching Into Dermatology, 2007-2018.

    Narang, Jatin / Eversman, Anna / Kalra, Mehak / Morgan, Frederick / Obi, Elizabeth / Russell, Emma R / Wei, Angela H / Zheng, David X / Osei-Koomson, Wilhemina / Nowacki, Amy S / Carroll, Bryan T / Sharma, Timmie R

    JAMA dermatology

    2021  

    Abstract: Importance: According to the National Residency Matching Program's biennial Charting Outcomes in the Match (NRMP ChOM) reports, the mean number of research items of matched allopathic dermatology applicants has nearly tripled since 2007, rising from 5.7 ...

    Abstract Importance: According to the National Residency Matching Program's biennial Charting Outcomes in the Match (NRMP ChOM) reports, the mean number of research items of matched allopathic dermatology applicants has nearly tripled since 2007, rising from 5.7 to 14.7. Research items are self-reported by applicants and serve as an approximation of research output. Because the NRMP research items field is unverified and reported as an aggregate of several different research pursuits, it may not be an accurate representation of applicant research output.
    Objective: To determine if the rise in NRMP-reported data is associated with a rise in verifiable, indexed publications from matched allopathic dermatology applicants from 2007 to 2018.
    Design, setting, and participants: Cross-sectional study including a bibliometric analysis on accepted applicant research output among 2234 matched allopathic dermatology applicants, with a total of 6229 publications, in dermatology residency programs for the years 2007, 2009, 2011, 2014, 2016, and 2018.
    Main outcome and measures: The primary outcomes were the mean number of peer-reviewed indexed publications and mean number of NRMP ChOM research items. Secondary outcomes assessed the quality of indexed publications by analyzing article type and journal of publication.
    Results: From 2007 to 2018, the mean number of indexed publications per matched dermatology applicant increased from 1.6 to 4.7 (203% increase). Indexed publications consistently compose a minority of NRMP ChOM research items (28.8% across the 6 years of the study). Nonindexed research items increased at more than double the rate of indexed publications. Bibliometric analysis showed that all other types of publications are increasing at a rate of 6 to 9 times that of basic science publications, dermatology-related publications increased at 5 times the rate of non-dermatology publications, and publications in lower-impact factor dermatology journals increased at 4 times the rate of publications in higher-impact factor dermatology journals.
    Conclusions and relevance: This cross-sectional study provides data on the research output of matched dermatology applicants. Indexed publications compose a minority of NRMP research items. Medical student self-reports of research output may emphasize research quantity over quality.
    Language English
    Publishing date 2021-06-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701761-8
    ISSN 2168-6084 ; 2168-6068
    ISSN (online) 2168-6084
    ISSN 2168-6068
    DOI 10.1001/jamadermatol.2021.2000
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Factors associated with matching into research-focused dermatology residency programs.

    Eversman, Anna / Narang, Jatin / Zheng, David X / Wei, Angela H / Russell, Emma R / Osei-Koomson, Wilhemina / Obi, Elizabeth / Morgan, Frederick / Kalra, Mehak / Nowacki, Amy S / Carroll, Bryan T / Sharma, Timmie R

    Archives of dermatological research

    2021  Volume 314, Issue 10, Page(s) 991–994

    Abstract: Although dermatology is one of the most competitive specialties to match into, there is limited transparency in the residency match process. In this retrospective cohort study of 2234 allopathic medical graduates, we identify applicant characteristics ... ...

    Abstract Although dermatology is one of the most competitive specialties to match into, there is limited transparency in the residency match process. In this retrospective cohort study of 2234 allopathic medical graduates, we identify applicant characteristics associated with matching into research oriented dermatology programs. Many of the statistically significant variables in our study, including PhD/MD status, graduating from a Top-25 NIH funded medical school, increasing total number of pre-residency publications (PRPs), and increasing number of high-impact PRPs, correlate with future academic employment. Although literature shows an association between an increasing number of first author PRPs and future academic employment, we did not find number of first or last author PRPs to be predictive of matching into a research oriented residency program. A more comprehensive evaluation of an applicant's research output, considering both the final products of an applicant's research endeavors and an applicant's role in various projects, may better approximate an applicant's commitment to academics.
    MeSH term(s) Dermatology ; Humans ; Internship and Residency ; Retrospective Studies ; United States
    Language English
    Publishing date 2021-08-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 130131-7
    ISSN 1432-069X ; 0340-3696
    ISSN (online) 1432-069X
    ISSN 0340-3696
    DOI 10.1007/s00403-021-02271-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Gender trends in research output among matched dermatology residency applicants.

    Zheng, David X / Kalra, Mehak K / Narang, Jatin / Eversman, Anna / Morgan, Frederick C / Obi, Elizabeth E / Osei-Koomson, Wilhemina / Russell, Emma R / Wei, Angela H / Levoska, Melissa A / Scott, Jeffrey F / Wong, Christina

    Journal of the American Academy of Dermatology

    2021  Volume 86, Issue 5, Page(s) e213–e214

    MeSH term(s) Dermatology/education ; Humans ; Internship and Residency
    Language English
    Publishing date 2021-12-11
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2021.09.073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Trends in geographic and home program preferences in the dermatology residency match: A retrospective cohort analysis.

    Narang, Jatin / Morgan, Frederick / Eversman, Anna / Kalra, Mehak / Osei-Koomson, Wilhemina / Obi, Elizabeth / Russell, Emma R / Wei, Angela H / Zheng, David X / Carroll, Bryan T / Sharma, Timmie R

    Journal of the American Academy of Dermatology

    2021  Volume 86, Issue 3, Page(s) 645–647

    MeSH term(s) Cohort Studies ; Dermatology/education ; Humans ; Internship and Residency ; Personnel Selection ; Retrospective Studies ; United States
    Language English
    Publishing date 2021-02-11
    Publishing country United States
    Document type Letter
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2021.02.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Identifying Key Genetic Regions for Cell Sheet Morphogenesis on Chromosome 2L Using a

    Fogerson, Stephanie M / Mortensen, Richard D / Moore, Regan P / Chiou, Hellen Y / Prabhu, Neel K / Wei, Angela H / Tsai, Daniel / Jadi, Othmane / Andoh-Baidoo, Kwabena / Crawford, Janice / Mudziviri, Murotiwamambo / Kiehart, Daniel P

    G3 (Bethesda, Md.)

    2020  Volume 10, Issue 11, Page(s) 4249–4269

    Abstract: Cell sheet morphogenesis is essential for metazoan development and homeostasis of animal form - it contributes to developmental milestones including gastrulation, neural tube closure, heart and palate formation and to tissue maintenance during wound ... ...

    Abstract Cell sheet morphogenesis is essential for metazoan development and homeostasis of animal form - it contributes to developmental milestones including gastrulation, neural tube closure, heart and palate formation and to tissue maintenance during wound healing. Dorsal closure, a well-characterized stage in
    MeSH term(s) Animals ; Chromosomes ; Drosophila/genetics ; Drosophila Proteins/genetics ; Drosophila melanogaster/genetics ; Embryo, Nonmammalian ; Embryonic Development ; Epidermis ; Morphogenesis/genetics
    Chemical Substances Drosophila Proteins
    Language English
    Publishing date 2020-11-05
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2629978-1
    ISSN 2160-1836 ; 2160-1836
    ISSN (online) 2160-1836
    ISSN 2160-1836
    DOI 10.1534/g3.120.401386
    Database MEDical Literature Analysis and Retrieval System OnLINE

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