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Article ; Online: Research on Cancer Molecular Typing Based on High-Throughput Sequencing Technology.

Wei, Dan

Computational and mathematical methods in medicine

2021 Volume 2021, Page(s) 9941475

Abstract: This paper studies the role of high-throughput measurement technology in cancer molecular typing. Based on the Dendrix algorithm, the model proposed in this paper selects the gene replication time as an inherent attribute that affects the frequency of ... ...

Abstract	This paper studies the role of high-throughput measurement technology in cancer molecular typing. Based on the Dendrix algorithm, the model proposed in this paper selects the gene replication time as an inherent attribute that affects the frequency of gene mutations and adds it to the model. After setting the size of the gene set, compared with the Dendrix algorithm, the model does not need to delete the gene set that has been found in the process of searching the pathway, and it can find more driving pathway gene sets. Based on the high coverage and high exclusivity of the driving gene set in the pathway and the influence of gene covariates, this paper constructs an adaptive multiobjective optimization model. In order to overcome the problem of gene mutation heterogeneity, this model introduces gene covariates as the weight of gene mutation frequency so that the model is adaptive to each gene. The analysis of the research results shows the reliability of high-throughput sequencing technology.
MeSH term(s)	Algorithms ; High-Throughput Nucleotide Sequencing ; Humans ; Molecular Typing ; Neoplasms/genetics ; Reproducibility of Results ; Technology
Language	English
Publishing date	2021-12-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	2252430-7
ISSN	1748-6718 ; 1748-670X ; 1027-3662
ISSN (online)	1748-6718
ISSN	1748-670X ; 1027-3662
DOI	10.1155/2021/9941475
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Article: Bayesian estimation for the random moderation model: effect size, coverage, power of test, and type І error.

Wei, Dan / Zhan, Peida

Frontiers in psychology

2023 Volume 14, Page(s) 1048842

Abstract: The random moderation model (RMM) was developed based on a two-level regression model to cope with heteroscedasticity in moderation analysis, and normal-distributed-based maximum likelihood (NML) estimation was developed to estimate the RMM. To present ... ...

Abstract	The random moderation model (RMM) was developed based on a two-level regression model to cope with heteroscedasticity in moderation analysis, and normal-distributed-based maximum likelihood (NML) estimation was developed to estimate the RMM. To present an alternative to the NML, this article discusses the effectiveness of Bayesian estimation for the RMM, aiming to explore a more practical method using the popular software Mplus. Through a simulation study, the RMM based on Bayesian estimation was investigated and compared to maximum likelihood (ML) estimations, including the NML and the default ML estimation in Mplus. The results indicated that the Bayesian approach outperformed the two ML estimations. It showed (a) higher accuracy for estimation of the effect size of the moderation effect; (b) higher 95% credibility interval coverage of the true value of the moderation effect; and (c) well-controlled and more stable type I error rates, while powers comparable to the ML estimations were provided.
Language	English
Publishing date	2023-07-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2023.1048842
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Impacts of the Property Assessed Clean Energy (PACE) program on the economy of California.

Rose, Adam / Wei, Dan

Energy policy

2023 Volume 137, Page(s) None

Abstract: The Property Assessed Clean Energy (PACE) Program is an innovative financing approach to meeting environmental goals. PACE financing is structured as an assessment to the property and paid along with the property tax bill. In addition to the direct ... ...

Abstract	The Property Assessed Clean Energy (PACE) Program is an innovative financing approach to meeting environmental goals. PACE financing is structured as an assessment to the property and paid along with the property tax bill. In addition to the direct environmental benefits, it also yields co-benefits of enhanced economic output and employment. This paper estimates the economic impacts of PACE in California by one of its major financing companies. These impacts include direct spending on structural improvements, reduction in spending on centralized power and water services, reallocation of spending from energy and water bills savings, and solar investment tax credits, among others. It also includes general equilibrium effects of these various factors. Our results indicate PACE financing yields sizable economic benefits. At the same time, the increased economic activity results in increased energy and water use that partially offsets some of the direct environmental gains. Furthermore, PACE has been subject to criticism because it gives financing companies the first lien on mortgages and because of anecdotal examples of some customers being lured by unscrupulous contractors. The direct environmental benefits and economic co-benefits of PACE should be factored into the policy debate over whether the Program should be further expanded or regulated.
Language	English
Publishing date	2023-10-20
Publishing country	England
Document type	Journal Article
ISSN	0301-4215
ISSN	0301-4215
DOI	10.1016/j.enpol.2019.111087
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Article: [Simultaneous determination of 76 pesticide residues in the traditional Chinese medicine by magnetic hydrophilic-lipophilic-balanced materials assisted matrix solid phase dispersion extraction-high performance liquid chromatography-tandem mass spectrometry].

Wei, Dan / Guo, Ming

Se pu = Chinese journal of chromatography

2022 Volume 40, Issue 4, Page(s) 313–322

Abstract: Traditional Chinese medicine (TCM) is gaining popularity worldwide, but its quality is often affected by excessive pesticide residues during cultivation and production. A sensitive and reliable method for the simultaneous determination of multi-residue ... ...

Abstract	Traditional Chinese medicine (TCM) is gaining popularity worldwide, but its quality is often affected by excessive pesticide residues during cultivation and production. A sensitive and reliable method for the simultaneous determination of multi-residue pesticides in TCMs is the key to guarantee the quality and safety of TCMs. In this study, broad-spectrum hydrophilic-lipophilic balanced magnetic adsorbents were prepared for the magnetic matrix solid phase dispersion (MMSPD) extraction of 76 pesticides from three different TCMs before their detection by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). Unlike the traditional matrix solid phase dispersion (MSPD), which required tedious SPE column packing, an external magnetic field was employed in our method for magnetic isolation and extraction from TCM samples, followed by grounding adsorption. First, broad-spectrum hydrophilic-lipophilic balanced magnetic adsorbents, Fe
MeSH term(s)	Chromatography, High Pressure Liquid ; Magnetic Phenomena ; Medicine, Chinese Traditional ; Pesticide Residues/analysis ; Spectroscopy, Fourier Transform Infrared ; Tandem Mass Spectrometry
Chemical Substances	Pesticide Residues
Language	Chinese
Publishing date	2022-04-12
Publishing country	China
Document type	Journal Article
ISSN	1000-8713
ISSN	1000-8713
DOI	10.3724/SP.J.1123.2021.08014
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Article ; Online: Key issues to consider toward an efficient constructed wetland-microbial fuel cell: the idea and the reality.

Li, Diaodiao / Zhao, Yaqian / Wei, Dan / Tang, Cheng / Wei, Ting

Environmental science and pollution research international

2024 Volume 31, Issue 8, Page(s) 11559–11575

Abstract: The research on constructed wetland (CW) and microbial fuel cell (MFC) has been separate studies worldwide with crucial achievements being made in both fields. Due to environmentally friendly feature (of CW) and rich microbial population and excellent ... ...

Abstract	The research on constructed wetland (CW) and microbial fuel cell (MFC) has been separate studies worldwide with crucial achievements being made in both fields. Due to environmentally friendly feature (of CW) and rich microbial population and excellent electrode catalytic activity (of MFC), CW and MFC have their own anticipated application prospect in wastewater purification and biological electricity generation. More significantly, the idea of embedding MFC into CW to form CW-MFC expands the scope for both of them and this has received much interest in recent years due to its striking features of sewage treatment efficiency, electricity generation, sustainability, and environmental friendliness. The increasing interest and the lack of soul of CW-MFC emerging to the new researchers reflect the need to recall the idea and summarize its development with regard to achieving its reality via some key issues This forms the basis of the paper. The paper also includes how to enhance the efficiency of electricity generation and supplement energy consumption, the degradation of emerging pollutants, and the degradation mechanism as well as the potential joint application of CW-MFC with other treatment technique. A mass of CW-MFC design parameters has been synthesized from the literature. Challenges and potential directions of CW-MFC in the future are prospected. It is expected that the paper can serve as a linkage for bridging knowledge gaps for further studies of CW-MFC.
MeSH term(s)	Bioelectric Energy Sources ; Wetlands ; Wastewater ; Electricity ; Electrodes
Chemical Substances	Wastewater
Language	English
Publishing date	2024-01-16
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-024-31984-0
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Article ; Online: A Calcination-Free Sol-Gel Method to Prepare TiO

Yang, Kang / Wei, Dan / Jia, Chunman / Li, Jianwei

ChemPlusChem

2023 Volume 88, Issue 11, Page(s) e202300172

Abstract: In recent years, the sol-gel method has been extensively utilized to develop efficient and stable organic semiconductor composite titanium dioxide ( ... ...

Abstract	In recent years, the sol-gel method has been extensively utilized to develop efficient and stable organic semiconductor composite titanium dioxide (TiO
Language	English
Publishing date	2023-06-12
Publishing country	Germany
Document type	Journal Article
ISSN	2192-6506
ISSN (online)	2192-6506
DOI	10.1002/cplu.202300172
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Article ; Online: Visible light-driven highly-efficient hydrogen production by a naphthalene imide derivative-sensitized TiO

Wei, Dan / Yang, Kang / Jia, Chunman / Li, Jianwei

Chemical communications (Cambridge, England)

2023 Volume 59, Issue 56, Page(s) 8676–8679

Abstract: Sensitizing titanium dioxide ( ... ...

Abstract	Sensitizing titanium dioxide (TiO
Language	English
Publishing date	2023-07-11
Publishing country	England
Document type	Journal Article
ZDB-ID	1472881-3
ISSN	1364-548X ; 1359-7345 ; 0009-241X
ISSN (online)	1364-548X
ISSN	1359-7345 ; 0009-241X
DOI	10.1039/d3cc01696j
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Article: Comprehensive nursing intervention improves quality of life and reduces hospitalization time and expense in elderly patients with severe heart failure undergoing rh-BNP treatment.

Yu, Sujun / Wei, Dan / Shi, Nian

American journal of translational research

2023 Volume 15, Issue 8, Page(s) 5239–5248

Abstract: Objective: This study was designed to explore the efficacy of comprehensive nursing intervention in elderly patients with severe heart failure (SHF) treated by recombinant human brain natriuretic peptide (rh-BNP).: Methods: A retrospective analysis ... ...

Abstract	Objective: This study was designed to explore the efficacy of comprehensive nursing intervention in elderly patients with severe heart failure (SHF) treated by recombinant human brain natriuretic peptide (rh-BNP). Methods: A retrospective analysis was made on 131 patients with SHF treated with rh-BNP in Wuhan Asia Cardiology Hospital from May 2019 to May 2022. Of them, 71 patients who received routine nursing care between May 2019 and December 2021 were assigned to the control group, and 60 patients who received comprehensive nursing between January 2022 and May 2022 were assigned to the observation group. The changes in quality of life (QoL) before and after nursing and the occurrence of adverse events after nursing were counted and compared between the two groups. The two groups were compared reagarding changes in anxiety and depression scores before and after nursing, as well as hospitalization expenses and hospitalization time. The left ventricular end-diastolic volume (LVEDV) and left ventricular ejection fraction (LVEF) of patients were determined. The nursing satisfaction of the two groups was evaluated. Additionally, logistic regression was carried out to analyze the risk factors for adverse events. Results: The control group had lower QoL scores than the observation group after nursing (P < 0.0001). The control group got significantly higher self-rating anxiety scale (SAS) and self-rating depression scale (SDS) scores than the observation group (P < 0.0001). The control group showed lower levels of LVEDV and LVEF than the observation group (P < 0.0001). The control group experienced greatly longer hospitalization time than the observation group, and also had a higher hospitalization expense than the observation group (P < 0.001). The observation group expressed much higher nursing satisfaction than the control group (P=0.007). Additionally, according to multivariate logistic regression analysis, age, hypertension, and diabetes mellitus were independent risk factors for adverse events (P < 0.05). Conclusion: For elderly SHF patients treated by rh-BNP, comprehensive nursing intervention can contribute to higher QoL, shorter hospitalization time, lower hospitalization expense, and milder negative emotions, but did not correlate with short-term adverse cardiovascular events.
Language	English
Publishing date	2023-08-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2471058-1
ISSN	1943-8141
ISSN	1943-8141
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Prevention and Treatment of Anastomotic Strictures After Procedure for Prolapse and Hemorrhoids.

Wei, Dan / Jiang, Peng / Gao, Ran / Zhao, Yan

Risk management and healthcare policy

2023 Volume 16, Page(s) 1351–1357

Abstract: Procedure for Prolapse and Hemorrhoids (PPH), also known as circular stapled hemorrhoidectomy, is a common method of treating hemorrhoids due to its low risk of complications and minimal postoperative pain. Several complications have appeared alongside ... ...

Abstract	Procedure for Prolapse and Hemorrhoids (PPH), also known as circular stapled hemorrhoidectomy, is a common method of treating hemorrhoids due to its low risk of complications and minimal postoperative pain. Several complications have appeared alongside the rise of treated cases, however, and this has led to a progressive slowing of the clinical use of PPH in recent years. Anastomotic stenosis is one of the most common complications of PPH, but the greater amount of tissue removed and the speed with which it can heal make it the best choice for patients with severe prolapsed annular hemorrhoids or rectal mucosal prolapse. Therefore, academics continue to comprehensively study PPH to take advantage of annular resection and reduce complications. In this paper, we analyzed the causes, intraoperative warnings, and postoperative therapy of anastomotic stenosis induced by PPH, with an eye toward scientific application in the anorectal field, based on the experience of clinical applications.
Language	English
Publishing date	2023-07-26
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2495128-6
ISSN	1179-1594
ISSN	1179-1594
DOI	10.2147/RMHP.S407021
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Article ; Online: Blood flow characterization in nailfold capillary using optical flow-assisted two-stream network and spatial-temporal image.

Chen, Shupin / Wei, Dan / Gu, Shenming / Yang, Zhangru

Biomedical physics & engineering express

2023 Volume 9, Issue 4

Abstract: The blood flow velocity in the nailfold capillary is an important indicator of the status of microcirculation. The conventional manual processing method is both laborious and prone to human artifacts. A feasible way to solve this problem is to use ... ...

Abstract	The blood flow velocity in the nailfold capillary is an important indicator of the status of microcirculation. The conventional manual processing method is both laborious and prone to human artifacts. A feasible way to solve this problem is to use machine learning to assist in image processing and diagnosis. Inspired by the Two-Stream Convolutional Networks, this study proposes an optical flow-assisted two-stream network to segment nailfold blood vessels. Firstly, we use U-Net as the spatial flow network and the dense optical flow as the temporal stream. The results show that the optical flow information can effectively improve the integrity of the segmentation of blood vessels. The overall accuracy is 94.01 %, the Dice score is 0.8099, the IoU score is 0.6806, and the VOE score is 0.3194. Secondly, The flow velocity of the segmented blood vessel is determined by constructing the spatial-temporal (ST) image. The blood flow velocity evaluated is consistent with the typical blood flow speed reported. This study proposes a novel two-stream network for blood vessel segmentation of nailfold capillary images. Combined with ST image and line detection method, it provides an effective workflow for measuring the blood flow velocity of nailfold capillaries.
MeSH term(s)	Humans ; Capillaries/physiology ; Optic Flow ; Rivers ; Microcirculation ; Image Processing, Computer-Assisted/methods
Language	English
Publishing date	2023-06-13
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2057-1976
ISSN (online)	2057-1976
DOI	10.1088/2057-1976/acdb7c
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