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  1. Article ; Online: Rethinking Queer (Asian) Studies: Geopolitics, Covid-19, and Post-Covid Queer Theories and Mobilities.

    Wei, John

    Journal of homosexuality

    2023  Volume 71, Issue 6, Page(s) 1442–1464

    Abstract: This paper considers queer studies in the global geopolitical hotspot of Asia, as well as how we can reimagine queer theories through both the Covid-19 pandemic and the intensified regional and global superpower competition and geopolitical tensions. It ... ...

    Abstract This paper considers queer studies in the global geopolitical hotspot of Asia, as well as how we can reimagine queer theories through both the Covid-19 pandemic and the intensified regional and global superpower competition and geopolitical tensions. It argues for a rethinking of queer studies through today's international relations and geopolitical complications in a sociological political economy. The aim is to connect critical studies with analyses of economic and social class structures, an approach that has been substantiated by the current crises, and to present an expanded queer mobility theory with two brief case studies (mini-critiques) of the current socioeconomic conditions facing marginalized people under Covid-19 and the changing geopolitical landscape. In so doing, this paper actively explores what queer studies can do and can be through the current historical turning point of the pandemic and geopolitical rivalry toward potential post-Covid socioeconomic revival and recovery.
    MeSH term(s) Humans ; Sexual and Gender Minorities ; Pandemics ; COVID-19 ; Gender Identity ; Asia
    Language English
    Publishing date 2023-01-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193138-6
    ISSN 1540-3602 ; 0091-8369
    ISSN (online) 1540-3602
    ISSN 0091-8369
    DOI 10.1080/00918369.2023.2174471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1141: Show issues Location:
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  2. Article ; Online: Stretched Kinship: Parental Rejection and Acceptance of Queer Youth in Chinese Families.

    Wei, John

    Journal of homosexuality

    2022  Volume 70, Issue 9, Page(s) 1847–1866

    Abstract: Kinship has been the primary concern among young queer people in today's China and other parts of Asia under the strong and ongoing familism, who often find it challenging to come out and negotiate their sexuality with their parental family. This paper ... ...

    Abstract Kinship has been the primary concern among young queer people in today's China and other parts of Asia under the strong and ongoing familism, who often find it challenging to come out and negotiate their sexuality with their parental family. This paper adopts the concept of
    MeSH term(s) Adolescent ; Child ; Female ; Humans ; Male ; China ; East Asian People/psychology ; Parents/psychology ; Sexual and Gender Minorities/psychology ; Sexual Behavior/ethnology ; Sexual Behavior/psychology ; Rejection, Psychology ; Asia ; Parent-Child Relations/ethnology ; Family Support/psychology ; Social Status
    Language English
    Publishing date 2022-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193138-6
    ISSN 1540-3602 ; 0091-8369
    ISSN (online) 1540-3602
    ISSN 0091-8369
    DOI 10.1080/00918369.2022.2043130
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: Clinical Research Methods for Surgeons

    Penson, David F. / Wei, John T.

    2007  

    Author's details edited by David F. Penson, John T. Wei
    Keywords Surgery
    Language English
    Publisher Humana Press Inc
    Publishing place Totowa, NJ
    Document type Book ; Online
    HBZ-ID TT050387061
    ISBN 978-1-588-29326-8 ; 978-1-597-45230-4 ; 1-588-29326-2 ; 1-597-45230-0
    DOI 10.1007/978-1-59745-230-4
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Urinary biomarkers for prostate cancer.

    Wei, John T

    Current opinion in urology

    2015  Volume 25, Issue 1, Page(s) 77–82

    Abstract: Purpose of review: The field of urology has been beset by several major trends that have affected the early detection of prostate cancer. These stem primarily from a backlash against overdiagnosis due to prostate specific antigen-based screening efforts ...

    Abstract Purpose of review: The field of urology has been beset by several major trends that have affected the early detection of prostate cancer. These stem primarily from a backlash against overdiagnosis due to prostate specific antigen-based screening efforts and are epitomized by the US Preventive Services Task Force giving prostate specific antigen-based prostate cancer screening a 'D' recommendation. Consequently, the active surveillance strategy for low-risk prostate cancer has become commonplace, leading many to ask how best to follow these patients. More importantly, this public outcry has shifted the focus of early detection from an effort to diagnose any and all prostate cancers to an effort to diagnose only 'high-risk' cancer. Along with a trend for minimally invasive procedures, these forces have challenged the early detection field to more efficiently identify clinically significant prostate cancers at an early stage while limiting the number of biopsies.
    Recent findings: With US Food and Drug Administration approval, prostate cancer antigen 3 has emerged as the first bona-fide urinary biomarker for prostate cancer. Using the same platform, investigators have developed a second urinary test based on TMPRSS2:erg fusion. Recent literature supports the use of these biomarkers as a combined panel that improves risk evaluation in the setting of prostate cancer detection. Early works for applying urinary biomarkers for active surveillance are underway. Other biomarkers in the pipeline will require further prevalidation and validation work.
    Summary: Recent literature would support that urinary biomarkers have a clear role to supplement risk evaluation for men undergoing prostate biopsy and for prognostication.
    MeSH term(s) Antigens, Neoplasm/urine ; Biomarkers, Tumor/urine ; Humans ; Male ; Oncogene Fusion ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/urine ; Serine Endopeptidases/genetics ; Trans-Activators/genetics ; Transcriptional Regulator ERG
    Chemical Substances Antigens, Neoplasm ; Biomarkers, Tumor ; ERG protein, human ; Trans-Activators ; Transcriptional Regulator ERG ; prostate cancer antigen 3, human ; Serine Endopeptidases (EC 3.4.21.-) ; TMPRSS2 protein, human (EC 3.4.21.-)
    Language English
    Publishing date 2015-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1091792-5
    ISSN 1473-6586 ; 0963-0643
    ISSN (online) 1473-6586
    ISSN 0963-0643
    DOI 10.1097/MOU.0000000000000133
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: How much worse will my voiding symptoms get over time?

    Wei, John T

    The Journal of urology

    2014  Volume 191, Issue 1, Page(s) 15–16

    MeSH term(s) Female ; Humans ; Lower Urinary Tract Symptoms/epidemiology ; Male ; Sleep Wake Disorders/epidemiology
    Language English
    Publishing date 2014-01
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1016/j.juro.2013.10.047
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 331: Show issues

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  6. Book: Gratian the theologian

    Wei, John C

    (Studies in medieval and early modern canon law ; Volume 13)

    2016  

    Author's details John C. Wei
    Series title Studies in medieval and early modern canon law ; Volume 13
    Keywords Penance/History of doctrines ; Theology/History
    Language English
    Size pages cm
    Publisher Catholic University of America Press
    Publishing place Washington, D.C
    Document type Book
    Note Includes bibliographical references and index
    ISBN 9780813228037 ; 0813228034
    Database Former special subject collection: coastal and deep sea fishing

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  7. Article: Gratian's "Decretum" in France and Halberstadt

    Wei, John C

    Rechtshandschriften des deutschen Mittelalters : Produktionswege und Importwege , p. 363-383

    2015  , Page(s) 363–383

    Author's details John C. Wei
    Language English
    Publisher Harrassowitz
    Publishing place Wiesbaden
    Document type Article
    ISBN 978-3-447-10293-3 ; 3-447-10293-4
    Database Former special subject collection: coastal and deep sea fishing

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  8. Thesis ; Online: Immunomodulatory Effects of Soy Isoflavones Genistein and Daidzein

    Wei, John

    2011  

    Abstract: Soybeans are the most common source of isoflavones in human food, and have been shown to have anti-inflammatory and anti-oxidant properties. We hypothesize that isoflavones modulate both Th1 and Th2 immune responses by regulating dendritic cell (DC) ... ...

    Abstract Soybeans are the most common source of isoflavones in human food, and have been shown to have anti-inflammatory and anti-oxidant properties. We hypothesize that isoflavones modulate both Th1 and Th2 immune responses by regulating dendritic cell (DC) function. We have addressed this hypothesis with in vitro DC activation and coculture models, and in vivo models of lipopolysaccharide (LPS) and cholera toxin (CT)-induced sensitization to antigen. In vitro, we found significant suppressive effects of isoflavones on DC surface molecule expression and cytokine secretion, and subsequently, the ability of these DCs to induce T cell and natural killer (NK) cell activity. In vivo, we found that isoflavones cause significant suppression of LPS and CT-induced immunity, and that isoflavones may exert effects in their active forms at the site of sensitization, or as conjugates in blood. These results indicate that isoflavones may have a significant role in both Th1 and Th2-mediated sensitization.
    Keywords Immunology
    Subject code 610
    Language ENG
    Publishing date 2011-01-01 00:00:01.0
    Publisher Mount Sinai School of Medicine
    Publishing country us
    Document type Thesis ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Limitations of a contemporary prostate biopsy: the blind march forward.

    Wei, John T

    Urologic oncology

    2009  Volume 28, Issue 5, Page(s) 546–549

    Abstract: In an attempt to reduce morbidity, focal targeted therapies and active surveillance have become increasingly popular treatment choices for localized prostate cancer. However, these modalities rely heavily on accurate and reliable tumor localization ... ...

    Abstract In an attempt to reduce morbidity, focal targeted therapies and active surveillance have become increasingly popular treatment choices for localized prostate cancer. However, these modalities rely heavily on accurate and reliable tumor localization information provided by a prostate biopsy. Evidence that our contemporary biopsy techniques can do little more than detect some prostate cancers is notably lacking. What is meant by the accuracy and reliability of a prostate biopsy and why they are such important concepts to focal therapy and active surveillance are discussed.
    MeSH term(s) Biopsy ; Humans ; Male ; Prostate/pathology ; Prostatic Neoplasms/pathology ; Reproducibility of Results
    Language English
    Publishing date 2009-06-24
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1336505-8
    ISSN 1873-2496 ; 1078-1439
    ISSN (online) 1873-2496
    ISSN 1078-1439
    DOI 10.1016/j.urolonc.2009.12.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4817: Show issues Location:
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  10. Article ; Online: Similar Efficacy Observed for First-Line Immunotherapy in Racial/Ethnic Minority Patients With Metastatic NSCLC.

    Lee, Matthew / Liu, Jianyou / Miao, Emily / Wang, Shuai / Zhang, Frank / Wei, John / Chung, Julie / Xue, Xiaonan / Halmos, Balazs / Hosgood, H Dean / Cheng, Haiying

    Journal of the National Comprehensive Cancer Network : JNCCN

    2023  Volume 21, Issue 12, Page(s) 1269–1280.e5

    Abstract: Background: Limited data exist on the impact of immunotherapy use in ethnic minority patients with non-small cell lung cancer (NSCLC), because they have been underrepresented in immunotherapy trials. This study aims to evaluate race/ethnicity and other ... ...

    Abstract Background: Limited data exist on the impact of immunotherapy use in ethnic minority patients with non-small cell lung cancer (NSCLC), because they have been underrepresented in immunotherapy trials. This study aims to evaluate race/ethnicity and other demographic, socioeconomic, and clinical factors of patients with metastatic NSCLC treated with first-line immunotherapy.
    Methods: A retrospective cohort study of 5,920 patients diagnosed with lung cancer treated at Montefiore Einstein Cancer Center from January 1, 2013, to June 1, 2022, was used to identify patients with metastatic NSCLC without EGFR, ALK, or ROS1 alterations who underwent first-line immunotherapy (n=248). The primary endpoint was overall survival (OS), with secondary endpoints of progression-free survival (PFS) and time to discontinuation (TTD) from the start of immunotherapy.
    Results: Among the 248 patients, median follow-up time was 12.0 months, median age at start of treatment was 66 years, and 39.1% were non-Hispanic Black, 30.2% were Hispanic, and 30.7% were non-Hispanic White. OS (P=.39), PFS (P=.29), and TTD (P=.98) were similar among racial/ethnic groups. Patients with an ECOG performance status (PS) of <2 at the start of immunotherapy had longer OS compared with those with ECOG PS of ≥2 (P<.0001). PD-L1 expression (<50% vs ≥50%; P=.03) and body mass index (BMI) (P=.01) were also found to be associated with PFS, and ECOG PS (P<.0001) and BMI (P=.02) were associated with TTD. In a multivariate analysis of OS and PFS, ECOG PS was the only variable found to be significant.
    Conclusions: Our study observed similar benefits of immunotherapy in patients with metastatic NSCLC in different racial and ethnic groups. Furthermore, ECOG PS was associated with OS, and PD-L1 expression and BMI were associated with PFS and TTD. These findings help identify potential factors associated with outcomes and care while patients are undergoing immunotherapy.
    MeSH term(s) Humans ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Lung Neoplasms/drug therapy ; Ethnicity ; B7-H1 Antigen/therapeutic use ; Retrospective Studies ; Ethnic and Racial Minorities ; Protein-Tyrosine Kinases ; Minority Groups ; Proto-Oncogene Proteins ; Immunotherapy
    Chemical Substances B7-H1 Antigen ; Protein-Tyrosine Kinases (EC 2.7.10.1) ; Proto-Oncogene Proteins
    Language English
    Publishing date 2023-12-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2250759-0
    ISSN 1540-1413 ; 1540-1405
    ISSN (online) 1540-1413
    ISSN 1540-1405
    DOI 10.6004/jnccn.2023.7064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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