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  1. Article: Sub-MIC Antibiotics Modulate Productions of Outer Membrane Vesicles in Tigecycline-Resistant

    Li, Qianru / Li, Jun / He, Tao / Ji, Xing / Wei, Ruicheng / Yu, Meiling / Wang, Ran

    Antibiotics (Basel, Switzerland)

    2024  Volume 13, Issue 3

    Abstract: Antimicrobial resistance (AMR) has been recognized as one of the most important crises affecting global human health in the 21st century. Tigecycline is one of the last resort antibiotics for treating severe infections caused by multi-drug ... ...

    Abstract Antimicrobial resistance (AMR) has been recognized as one of the most important crises affecting global human health in the 21st century. Tigecycline is one of the last resort antibiotics for treating severe infections caused by multi-drug resistant
    Language English
    Publishing date 2024-03-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics13030276
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: RW-BP100-4D, a Promising Antimicrobial Candidate With Broad-Spectrum Bactericidal Activity.

    Tong, Xingqi / Li, Jun / Wei, Ruicheng / Gong, Lan / Ji, Xing / He, Tao / Wang, Ran

    Frontiers in microbiology

    2022  Volume 12, Page(s) 815980

    Abstract: With the rapid emergence and dissemination of antimicrobial resistance (AMR) genes in bacteria from animal, animal-derived food and human clinic, it is of great significance to develop new approaches to combat the multidrug-resistant bacteria. This study ...

    Abstract With the rapid emergence and dissemination of antimicrobial resistance (AMR) genes in bacteria from animal, animal-derived food and human clinic, it is of great significance to develop new approaches to combat the multidrug-resistant bacteria. This study presented a short linear antimicrobial peptide RW-BP100-4D, which was derived from RW-BP100 (RRLFRRILRWL-NH2) by transforming the N-terminal 4th amino acid from L- to D-enantiomer. This modification remarkably reduced the peptide cytotoxicity to mammalian cells, as indicated by hemolytic and cytotoxicity assays. Meanwhile, the antimicrobial activity of RW-BP100-4D was improved against a more variety of Gram-positive and Gram-negative bacteria (sensitive and resistant) as well as fungi. Also, RW-BP100-4D showed strong
    Language English
    Publishing date 2022-01-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2021.815980
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Facile synthesis of Au@Ag core–shell nanorod with bimetallic synergistic effect for SERS detection of thiabendazole in fruit juice

    Chen, Zhiyang / Sun, Yue / Shi, Jiyong / Zhang, Wen / Zhang, Xinai / Huang, Xiaowei / Zou, Xiaobo / Li, Zhihua / Wei, Ruicheng

    Food chemistry. 2022 Feb. 15, v. 370

    2022  

    Abstract: This study presented an effective and sensitive SERS substrate for rapid detection of thiabendazole (TBZ) in fruit samples. A core–shell gold/silver nanorod (Au@Ag NRs) has been synthesized as a bimetallic SERS-active substrate. The obtained substrate ... ...

    Abstract This study presented an effective and sensitive SERS substrate for rapid detection of thiabendazole (TBZ) in fruit samples. A core–shell gold/silver nanorod (Au@Ag NRs) has been synthesized as a bimetallic SERS-active substrate. The obtained substrate showed an excellent SERS effect because of the tunable plasmon resonance of Au NRs, the significantly enhanced effect of silver, and the bimetallic synergistic effect of Au@Ag NRs. Under optimal conditions, the substrate was used to detect TBZ in fresh apple juice and peach juice with limits of detection of 0.032 and 0.034 ppm respectively. In addition, the recovery rate was within a satisfactory range of 95–101%, indicating that the Au@Ag NRs substrate could be a SERS detection platform for fruit pesticides residues with great development potential.
    Keywords apple juice ; food chemistry ; fruits ; gold ; nanorods ; peach juice ; rapid methods ; silver ; synergism ; thiabendazole
    Language English
    Dates of publication 2022-0215
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2021.131276
    Database NAL-Catalogue (AGRICOLA)

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  4. Article: Solid-state fermentation with

    Zhang, Yongzhu / Wei, Ruicheng / Azi, Fidelis / Jiao, Linshu / Wang, Heye / He, Tao / Liu, Xianjin / Wang, Ran / Lu, Baiyi

    Frontiers in nutrition

    2022  Volume 9, Page(s) 972860

    Abstract: Fermented soybean products are favorite foods worldwide because of their nutritional value and health effects. In this study, solid-state fermentation (SSF) of soybeans ... ...

    Abstract Fermented soybean products are favorite foods worldwide because of their nutritional value and health effects. In this study, solid-state fermentation (SSF) of soybeans with
    Language English
    Publishing date 2022-09-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2022.972860
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Comprehensive Analysis of Antimicrobial, Heavy Metal, and Pesticide Residues in Commercial Organic Fertilizers and Their Correlation with Tigecycline-Resistant

    He, Tao / Li, Jun / Gong, Lan / Wang, Yang / Li, Ruichao / Ji, Xing / Luan, Fengting / Tang, Minmin / Zhu, Lei / Wei, Ruicheng / Wang, Ran

    Microbiology spectrum

    2023  , Page(s) e0425122

    Abstract: With the issue of the antimicrobial additive ban in feed in Chinese animal husbandry, it is important to determine the potential drivers of the spread of the newly discovered tigecycline- ... ...

    Abstract With the issue of the antimicrobial additive ban in feed in Chinese animal husbandry, it is important to determine the potential drivers of the spread of the newly discovered tigecycline-resistant
    Language English
    Publishing date 2023-03-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.04251-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Occurrence of seventeen veterinary antibiotics and resistant bacterias in manure-fertilized vegetable farm soil in four provinces of China

    Wei, Ruicheng / Tao He / Shengxin Zhang / Lei Zhu / Bin Shang / Zhaojun Li / Ran Wang

    Chemosphere. 2019 Jan., v. 215

    2019  

    Abstract: This study focused on the occurrence of seventeen veterinary antibiotics and six resistant bacterias in soils from the vegetable farms fertilized with animal manure in China. Seventeen veterinary antibiotics, including sulfonamides, quinolones, ... ...

    Abstract This study focused on the occurrence of seventeen veterinary antibiotics and six resistant bacterias in soils from the vegetable farms fertilized with animal manure in China. Seventeen veterinary antibiotics, including sulfonamides, quinolones, tetracyclines, macrolides and amphenicols, were detected by high performance liquid chromatography/tandem mass spectrometer in all the 53 soil samples collected in four provinces during August 2016. The concentrations of target antibiotics in the soil samples ranged from not detectable to 415.00 μg/kg dry weight with the mean residual levels of the five classes followed order: tetracyclines (82.75 μg/kg) > quinolones (12.78 μg/kg) > macrolides (12.24 μg/kg) > sulfonamides (2.61 μg/kg) > amphenicols (0.06 μg/kg). Moreover, the highest antibiotic levels were found mainly in soil from organic vegetable farms. Risk assessment by using the methods of risk quotient, suggested that oxytetracycline, chlortetracycline, enrofloxacin and ciprofloxacin could pose severe ecological risk in sampled soils. Resistant strains were isolated in 30 samples, with Escherichia coli and Klebsiella pneumonia found the dominant bacterial hosts with resistance genes. Antibiotic resistance genes, including tetA, tetB, qnrS, oqxA, sul1, sul2, ermA and floR, were detected in the strains resistant to: tetracyclines, quinolones, sulfonamides, macrolides and amphenicols resistance, respectively. Overall, there was a correlation between the results of antibiotic risk assessment with the detection of resistance genes from isolated strains in the soils.
    Keywords Escherichia coli ; Klebsiella pneumoniae ; agricultural soils ; animal manures ; antibiotic resistance genes ; chlortetracycline ; ciprofloxacin ; enrofloxacin ; farms ; high performance liquid chromatography ; hosts ; macrolides ; organic foods ; oxytetracycline ; risk ; risk assessment ; soil sampling ; spectrometers ; sulfonamides ; vegetables ; veterinary drugs ; China
    Language English
    Dates of publication 2019-01
    Size p. 234-240.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2018.09.152
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Facile synthesis of Au@Ag core-shell nanorod with bimetallic synergistic effect for SERS detection of thiabendazole in fruit juice.

    Chen, Zhiyang / Sun, Yue / Shi, Jiyong / Zhang, Wen / Zhang, Xinai / Huang, Xiaowei / Zou, Xiaobo / Li, Zhihua / Wei, Ruicheng

    Food chemistry

    2021  Volume 370, Page(s) 131276

    Abstract: This study presented an effective and sensitive SERS substrate for rapid detection of thiabendazole (TBZ) in fruit samples. A core-shell gold/silver nanorod (Au@Ag NRs) has been synthesized as a bimetallic SERS-active substrate. The obtained substrate ... ...

    Abstract This study presented an effective and sensitive SERS substrate for rapid detection of thiabendazole (TBZ) in fruit samples. A core-shell gold/silver nanorod (Au@Ag NRs) has been synthesized as a bimetallic SERS-active substrate. The obtained substrate showed an excellent SERS effect because of the tunable plasmon resonance of Au NRs, the significantly enhanced effect of silver, and the bimetallic synergistic effect of Au@Ag NRs. Under optimal conditions, the substrate was used to detect TBZ in fresh apple juice and peach juice with limits of detection of 0.032 and 0.034 ppm respectively. In addition, the recovery rate was within a satisfactory range of 95-101%, indicating that the Au@Ag NRs substrate could be a SERS detection platform for fruit pesticides residues with great development potential.
    MeSH term(s) Fruit and Vegetable Juices ; Gold ; Metal Nanoparticles ; Nanotubes ; Spectrum Analysis, Raman ; Thiabendazole/analysis
    Chemical Substances Gold (7440-57-5) ; Thiabendazole (N1Q45E87DT)
    Language English
    Publishing date 2021-09-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2021.131276
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: New matrix certified reference material for accurate measurement of ciprofloxacin residue in egg

    Yang, Mengrui / Liu, Fang / Wang, Min / Zhou, Jian / Wei, Ruicheng / Wang, Ran / Zhang, Liyuan / Jian, Lingbo / Wang, Tongtong

    Analytical and bioanalytical chemistry. 2020 Jan., v. 412, no. 3

    2020  

    Abstract: Matrix certified reference materials (CRMs) are an indispensable part of method validation and have played an important role in ensuring reliable analytical results. To retain similarity to real samples, a new matrix CRM for the mass fraction of ... ...

    Abstract Matrix certified reference materials (CRMs) are an indispensable part of method validation and have played an important role in ensuring reliable analytical results. To retain similarity to real samples, a new matrix CRM for the mass fraction of ciprofloxacin in whole liquid egg was developed by use of incurred materials with a target value corresponding to residue levels in real sample. The source materials were collected from laying hens following oral administration of ciprofloxacin. An optimized homogenization method and a strict bottling process were applied to bulk whole egg materials to prepare the CRM candidate. The mass fraction of ciprofloxacin in whole liquid egg was certified by a collaborative characterization program with eight accredited participating laboratories. Liquid chromatography coupled with isotope dilution mass spectrometry was studied as a reliable reference method for value assignment and was used by all participating laboratories. The certified value and expanded uncertainty (k = 2, at a confidence level of 95%) was 39.7 ± 5.2 μg/kg for ciprofloxacin in whole liquid egg. Homogeneity, long-term stability at -70 °C for 12 months, and short-term stability at -18 °C, 4 °C, and room temperature were assessed for 9 days. Additionally, uncertainties arising from inhomogeneity, instability, and characterization were analyzed in detail and fully estimated. This CRM would be a useful tool for validation of analytical methods and proficiency testing in ciprofloxacin residue analysis of egg. Graphical Abstract
    Keywords ambient temperature ; bottling ; ciprofloxacin ; eggs ; homogenization ; isotope dilution technique ; laying hens ; liquid chromatography ; liquid egg products ; mass spectrometry ; oral administration ; reference standards ; uncertainty
    Language English
    Dates of publication 2020-01
    Size p. 635-645.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    ISSN 1618-2642
    DOI 10.1007/s00216-019-02264-5
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Characterization of Acinetobacter indicus co-harbouring tet(X3) and blaNDM-1 of dairy cow origin.

    He, Tao / Li, Ruichao / Wei, Ruicheng / Liu, Dejun / Bai, Li / Zhang, Lili / Gu, Jili / Wang, Ran / Wang, Yang

    The Journal of antimicrobial chemotherapy

    2020  Volume 75, Issue 9, Page(s) 2693–2696

    MeSH term(s) Acinetobacter/genetics ; Acinetobacter Infections/veterinary ; Acinetobacter baumannii ; Animals ; Anti-Bacterial Agents ; Cattle ; Female ; Microbial Sensitivity Tests ; beta-Lactamases/genetics
    Chemical Substances Anti-Bacterial Agents ; beta-Lactamases (EC 3.5.2.6)
    Language English
    Publishing date 2020-04-11
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkaa182
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: New matrix certified reference material for accurate measurement of ciprofloxacin residue in egg.

    Yang, Mengrui / Liu, Fang / Wang, Min / Zhou, Jian / Wei, Ruicheng / Wang, Ran / Zhang, Liyuan / Jian, Lingbo / Wang, Tongtong

    Analytical and bioanalytical chemistry

    2020  Volume 412, Issue 3, Page(s) 635–645

    Abstract: Matrix certified reference materials (CRMs) are an indispensable part of method validation and have played an important role in ensuring reliable analytical results. To retain similarity to real samples, a new matrix CRM for the mass fraction of ... ...

    Abstract Matrix certified reference materials (CRMs) are an indispensable part of method validation and have played an important role in ensuring reliable analytical results. To retain similarity to real samples, a new matrix CRM for the mass fraction of ciprofloxacin in whole liquid egg was developed by use of incurred materials with a target value corresponding to residue levels in real sample. The source materials were collected from laying hens following oral administration of ciprofloxacin. An optimized homogenization method and a strict bottling process were applied to bulk whole egg materials to prepare the CRM candidate. The mass fraction of ciprofloxacin in whole liquid egg was certified by a collaborative characterization program with eight accredited participating laboratories. Liquid chromatography coupled with isotope dilution mass spectrometry was studied as a reliable reference method for value assignment and was used by all participating laboratories. The certified value and expanded uncertainty (k = 2, at a confidence level of 95%) was 39.7 ± 5.2 μg/kg for ciprofloxacin in whole liquid egg. Homogeneity, long-term stability at -70 °C for 12 months, and short-term stability at -18 °C, 4 °C, and room temperature were assessed for 9 days. Additionally, uncertainties arising from inhomogeneity, instability, and characterization were analyzed in detail and fully estimated. This CRM would be a useful tool for validation of analytical methods and proficiency testing in ciprofloxacin residue analysis of egg. Graphical Abstract.
    MeSH term(s) Animals ; Anti-Bacterial Agents/analysis ; Chickens ; Chromatography, High Pressure Liquid/methods ; Chromatography, High Pressure Liquid/standards ; Ciprofloxacin/analysis ; Drug Residues/analysis ; Eggs/analysis ; Food Analysis/methods ; Food Analysis/standards ; Limit of Detection ; Reference Standards ; Tandem Mass Spectrometry/methods ; Tandem Mass Spectrometry/standards
    Chemical Substances Anti-Bacterial Agents ; Ciprofloxacin (5E8K9I0O4U)
    Language English
    Publishing date 2020-01-02
    Publishing country Germany
    Document type Journal Article ; Validation Study
    ZDB-ID 201093-8
    ISSN 1618-2650 ; 0016-1152 ; 0372-7920
    ISSN (online) 1618-2650
    ISSN 0016-1152 ; 0372-7920
    DOI 10.1007/s00216-019-02264-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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