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  1. AU="Wei, Xiang"
  2. AU="Daniell, Esther"
  3. AU="Chou, Chau-Wen"
  4. AU=Kaur Supreet
  5. AU="Yun, Joho"
  6. AU="Tran, Bao G"
  7. AU="Ou Li"
  8. AU="Ting Chen" AU="Ting Chen"
  9. AU="Wilson, Jaymi"
  10. AU="Vane, Christopher H"
  11. AU="Mabbott, Donald"
  12. AU="Martín-Trejo, Jorge Alfonso"
  13. AU=Rieder Hans L

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  1. Buch ; Online ; E-Book: Atlas of thoracoscopic-lapacoscopic esophagectomy

    Zhang, Yi / Pan, Tiecheng / Wei, Xiang

    2018  

    Verfasserangabe Yi Zhang, Tiecheng Pan, Xiang Wei editors
    Schlagwörter Esophageal Neoplasms / surgery ; Esophagectomy / methods ; Thoracoscopy / methods ; Laparoscopy / methods ; Minimally Invasive Surgical Procedures / methods
    Thema/Rubrik (Code) 617.548
    Sprache Englisch
    Umfang 1 Online-Ressource (ix, 194 Seiten), Illustrationen
    Verlag Springer
    Erscheinungsort Singapore
    Erscheinungsland Singapur
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020082872
    ISBN 978-981-10-7569-8 ; 9789811075681 ; 981-10-7569-7 ; 9811075689
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  2. Artikel ; Online: Highly homogeneous zero-index metamaterials make devices more compact and perform better.

    Jiang, Wei-Xiang

    Light, science & applications

    2024  Band 13, Heft 1, Seite(n) 104

    Abstract: A highly homogeneous microwave zero-index metamaterial based on high-permittivity ... ...

    Abstract A highly homogeneous microwave zero-index metamaterial based on high-permittivity SrTiO
    Sprache Englisch
    Erscheinungsdatum 2024-05-06
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2662628-7
    ISSN 2047-7538 ; 2047-7538
    ISSN (online) 2047-7538
    ISSN 2047-7538
    DOI 10.1038/s41377-024-01458-6
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Enhancing deep learning pre-trained networks on diabetic retinopathy fundus photographs with SLIC-G.

    Lim, Wei Xiang / Chen, Zhiyuan

    Medical & biological engineering & computing

    2024  

    Abstract: Diabetic retinopathy disease contains lesions (e.g., exudates, hemorrhages, and microaneurysms) that are minute to the naked eye. Determining the lesions at pixel level poses a challenge as each pixel does not reflect any semantic entities. Furthermore, ... ...

    Abstract Diabetic retinopathy disease contains lesions (e.g., exudates, hemorrhages, and microaneurysms) that are minute to the naked eye. Determining the lesions at pixel level poses a challenge as each pixel does not reflect any semantic entities. Furthermore, the computational cost of inspecting each pixel is expensive because the number of pixels is high even at low resolution. In this work, we propose a hybrid image processing method. Simple Linear Iterative Clustering with Gaussian Filter (SLIC-G) for the purpose of overcoming pixel constraints. The SLIC-G image processing method is divided into two stages: (1) simple linear iterative clustering superpixel segmentation and (2) Gaussian smoothing operation. In such a way, a large number of new transformed datasets are generated and then used for model training. Finally, two performance evaluation metrics that are suitable for imbalanced diabetic retinopathy datasets were used to validate the effectiveness of the proposed SLIC-G. The results indicate that, in comparison to prior published works' results, the proposed SLIC-G shows better performance on image classification of class imbalanced diabetic retinopathy datasets. This research reveals the importance of image processing and how it influences the performance of deep learning networks. The proposed SLIC-G enhances pre-trained network performance by eliminating the local redundancy of an image, which preserves local structures, but avoids over-segmented, noisy clips. It closes the research gap by introducing the use of superpixel segmentation and Gaussian smoothing operation as image processing methods in diabetic retinopathy-related tasks.
    Sprache Englisch
    Erscheinungsdatum 2024-04-23
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 282327-5
    ISSN 1741-0444 ; 0025-696X ; 0140-0118
    ISSN (online) 1741-0444
    ISSN 0025-696X ; 0140-0118
    DOI 10.1007/s11517-024-03093-0
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Transapical beating-heart septal myectomy for hypertrophic cardiomyopathy patients with midventricular obstruction.

    Li, Jiangtao / Wei, Xiang

    Heliyon

    2024  Band 10, Heft 10, Seite(n) e31492

    Abstract: Background: We developed a novel minimally invasive transapical beating-heart septal myectomy (TA-BSM) procedure for patients with midventricular obstruction (MVO), without the aid of cardiopulmonary bypass. This study aims to describe the TA-BSM ... ...

    Abstract Background: We developed a novel minimally invasive transapical beating-heart septal myectomy (TA-BSM) procedure for patients with midventricular obstruction (MVO), without the aid of cardiopulmonary bypass. This study aims to describe the TA-BSM procedure for the relief of MVO and to detail the clinical outcomes in these patients.
    Methods: Sixty-one patients receiving TA-BSM for MVO were included: isolated MVO (n = 12) and combined MVO and subaortic obstruction (n = 49). We reviewed the electronic medical record to collect information on preoperative, intraoperative, and postoperative parameters.
    Results: The intraventricular pressure gradient after the resection was largely attenuated. On the catheter measurement, the median resting and provoked gradient decreased by 29.0 and 71.0 mm Hg, respectively. Likewise, the resting intraventricular gradient was successfully reduced from 58.0 to 11.0 mm Hg, and the maximal intraventricular gradient was reduced from 88.0 to 20.0 mm Hg at 6 months follow-up. In addition, all patients showed significantly improved MR and 37 of 42 patients with preoperative MR grade ≥2+ showed MR grade ≤1+ after TA-BSM. During the follow-up, no death was observed and no one had HCM-related rehospitalization. All patients reported improvement in symptoms and the mean New York Heart Association class improved from 3.0 (IQR, 3.0-3.0) preoperatively to 1.0 (IQR, 1.0-1.0) at 6 months follow-up.
    Conclusions: The TA-BSM procedure is a valuable therapy to relieve MVO, improving hemodynamics and providing satisfactory clinical outcomes. The procedure can also preserve favorable outcomes for patients with MVO and concomitant subaortic obstruction.
    Sprache Englisch
    Erscheinungsdatum 2024-05-17
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e31492
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: Efficacy of Omega-3 Intake in Managing Dry Eye Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    Wang, Wei-Xiang / Ko, Mei-Lan

    Journal of clinical medicine

    2023  Band 12, Heft 22

    Abstract: To explore the efficacy of omega-3 fatty acids (FAs) on patients suffering from dry eye disease (DED), a complex inflammatory condition, we reviewed data from PubMed, Embase, ClinicalTrials.gov, Web of Science, and Cochrane CENTRAL in the past 10 years ( ... ...

    Abstract To explore the efficacy of omega-3 fatty acids (FAs) on patients suffering from dry eye disease (DED), a complex inflammatory condition, we reviewed data from PubMed, Embase, ClinicalTrials.gov, Web of Science, and Cochrane CENTRAL in the past 10 years (2013 to 2023). These sources provided randomized clinical trials (RCTs) that examined the efficacy of omega-3 FAs on DED patients with accessible pre- and post-intervention data, excluding trials with overlapping participants, without omega-3 supplementation, or those lacking placebo control or quantitative assessments. Two independent reviewers extracted data related to dry eye symptom scores, tear break-up time (TBUT), Schirmer's tests, osmolarity, and corneal fluorescein staining (CFS), and the results were analyzed by Comprehensive Meta-Analysis software version 4. We incorporated 19 related RCTs assessed by the Cochrane Risk of Bias tool, encompassing 4246 DED patients with various etiologies. Patients given omega-3 treatment demonstrated more significant improvements in dry eye symptoms (Hedges' g = -1.047;
    Sprache Englisch
    Erscheinungsdatum 2023-11-10
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12227026
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  6. Artikel ; Online: Transapical beating-heart septal myectomy for hypertrophic cardiomyopathy with latent obstruction.

    Li, Jiangtao / Wei, Xiang

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2023  Band 65, Heft 1

    Abstract: Objectives: A novel transapical beating-heart septal myectomy (TA-BSM) procedure was performed for patients with latent obstruction through the left intercostal incision and without cardiopulmonary bypass. This study aims to demonstrate the experience ... ...

    Abstract Objectives: A novel transapical beating-heart septal myectomy (TA-BSM) procedure was performed for patients with latent obstruction through the left intercostal incision and without cardiopulmonary bypass. This study aims to demonstrate the experience of the TA-BSM procedure for patients with latent obstruction and compare outcomes to patients with resting obstruction.
    Methods: We studied 120 symptomatic hypertrophic obstructive cardiomyopathy patients (33 with latent obstruction and 87 with resting obstruction) who underwent TA-BSM. Demographic profiles, echocardiogram-derived ventricular morphology and haemodynamics and clinical outcomes were analysed.
    Results: There were no important differences in baseline clinical characteristics between patients with latent obstruction and resting obstruction, including age, symptoms, comorbidities and medical history. Patients with latent obstruction had lower basal septum thickness, higher midventricular wall thickness, smaller left atrial chamber size and more frequency of mitral subvalvular anomalies. There was no difference in early (<30 days) deaths (0/33 vs 1/87, P > 0.999) and mid-term survival between patients with latent obstruction and resting obstruction. At 6 months after surgery, 31 (93.9%) patients with latent obstruction and 80 (92.0%) with resting obstruction achieved optimal procedural success, which was defined as a maximal gradient (after provocation) <30 mmHg and mitral regurgitation ≤ grade 1+ without mortality. Maximal left ventricular outflow tract gradient, basal septum thickness, midventricular wall thickness, mitral regurgitation grade and left atrial chamber size were significantly decreased after TA-BSM. In the follow-up, the New York Heart Association class was significantly improved following surgery.
    Conclusions: TA-BSM preserved favourable gold-standard guideline desired outcomes through real-time echocardiographic-guided resection. Equipoise of outcomes for this procedure regardless of degree of resting left ventricular outflow tract gradients supports operative management with this approach in symptomatic patients with latent obstruction.
    Mesh-Begriff(e) Humans ; Mitral Valve Insufficiency/surgery ; Cardiac Surgical Procedures/methods ; Heart Septum/diagnostic imaging ; Heart Septum/surgery ; Treatment Outcome ; Ventricular Outflow Obstruction/diagnostic imaging ; Ventricular Outflow Obstruction/surgery ; Ventricular Outflow Obstruction/etiology ; Cardiomyopathy, Hypertrophic/complications ; Cardiomyopathy, Hypertrophic/diagnostic imaging ; Cardiomyopathy, Hypertrophic/surgery ; Heart Valve Diseases
    Sprache Englisch
    Erscheinungsdatum 2023-12-19
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezad425
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 2303: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Artikel ; Online: Outcomes and predictors of patients with moderate or severe functional mitral regurgitation and nonischemic dilated cardiomyopathy.

    Li, Jiangtao / Wei, Xiang

    Clinical cardiology

    2023  Band 46, Heft 8, Seite(n) 922–929

    Abstract: Background: Patients with functional mitral regurgitation (FMR) and nonischemic dilated cardiomyopathy (DCM) are associated with high mortality.: Objectives: Our study aimed to compare the clinical outcomes between different treatment strategies and ... ...

    Abstract Background: Patients with functional mitral regurgitation (FMR) and nonischemic dilated cardiomyopathy (DCM) are associated with high mortality.
    Objectives: Our study aimed to compare the clinical outcomes between different treatment strategies and identify predictors associated with the adverse outcomes.
    Methods: A total of 112 patients with moderate or severe FMR and nonischaemic DCM were included in our study. The primary composite outcome was all-cause death or unplanned hospitalization for heart failure. The secondary outcomes were individual components of the primary outcome and the cardiovascular death.
    Results: In this study, the primary composite outcome occurred in 26 patients (44.8%) in mitral valve repair (MVr) group and 37 patients (68.5%) in medical group (hazard ratio [HR], 0.28; 95% confidence interval [CI], 0.14-0.55; p < .001). The 1-, 3-, and 5-year survival rates for patients with MVr were 96.6%, 91.8%, and 77.4%, respectively, which were significantly higher than that of medical group: 81.2%, 71.9%, and 65.1%, respectively (HR, 0.32; 95% CI, 0.12-0.87; p = .03). Left ventricular ejection fraction (LVEF) < 41.5% (p < .001) and atrial fibrillation (p = .02) were independently associated with the primary outcome. LVEF < 41.5% (p = .007), renal insufficiency (p = .003), and left ventricular end-diastolic diameter > 66.5 mm (p < .001) were independently associated with heightened risk for all-cause death.
    Conclusion: Compared with medical therapy, MVr was associated with a better prognosis in patients with moderate or severe FMR and nonischemic DCM. We observed that LVEF < 41.5% was the only independent predictor of the primary outcome and all individual components of secondary outcomes.
    Mesh-Begriff(e) Humans ; Mitral Valve Insufficiency/diagnosis ; Mitral Valve Insufficiency/surgery ; Stroke Volume ; Ventricular Function, Left ; Cardiomyopathy, Dilated/complications ; Cardiomyopathy, Dilated/diagnosis ; Prognosis ; Treatment Outcome
    Sprache Englisch
    Erscheinungsdatum 2023-06-15
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 391935-3
    ISSN 1932-8737 ; 0160-9289
    ISSN (online) 1932-8737
    ISSN 0160-9289
    DOI 10.1002/clc.24067
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    Zs.A 1423: Hefte anzeigen Standort:
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  8. Artikel ; Online: Contemporary Surgical Management of Hypertrophic Cardiomyopathy.

    Schaff, Hartzell V / Wei, Xiang

    The Annals of thoracic surgery

    2023  Band 117, Heft 2, Seite(n) 271–281

    Abstract: More than half of symptomatic patients with hypertrophic cardiomyopathy (HCM) have left ventricular outflow tract (LVOT) obstruction. Septal reduction therapy by septal myectomy can dramatically relieve exertional dyspnea, chest pain, and presyncope in ... ...

    Abstract More than half of symptomatic patients with hypertrophic cardiomyopathy (HCM) have left ventricular outflow tract (LVOT) obstruction. Septal reduction therapy by septal myectomy can dramatically relieve exertional dyspnea, chest pain, and presyncope in properly selected patients and is an important management pathway for many patients. The distribution and degree of hypertrophy in patients with obstructive HCM are variable and, as discussed in this review, can influence clinical manifestations of the disease and surgical management. Subaortic septal hypertrophy is the most common phenotype of obstructive HCM associated with LVOT obstruction, but midventricular obstruction and apical hypertrophy may occur in isolation or in conjunction with subaortic septal hypertrophy. In many comprehensive HCM centers, transaortic septal myectomy is the preferred method of septal reduction therapy for symptomatic patients with obstructive HCM. Early surgical approaches aimed at alleviating left LVOT obstruction were hampered by a lack of understanding of the anatomy and pathophysiology of obstructive HCM. With the advent of Doppler echocardiography and, more recently, cardiac magnetic resonance imaging, surgeons can precisely assess the location and degree of obstruction, left ventricular size and function, and morphology and function of the mitral valve. This review discusses the current understanding of the role of septal myectomy in the management of patients with HCM and details contemporary operative methods.
    Mesh-Begriff(e) Humans ; Cardiac Surgical Procedures/methods ; Ventricular Outflow Obstruction, Left ; Cardiomyopathy, Hypertrophic/surgery ; Cardiomyopathy, Hypertrophic/complications ; Mitral Valve/surgery ; Hypertrophy/complications ; Ventricular Outflow Obstruction/surgery ; Ventricular Outflow Obstruction/complications ; Treatment Outcome
    Sprache Englisch
    Erscheinungsdatum 2023-10-31
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Review
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2023.10.026
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Intermittent horizontal mattress suture technique in aortic root anastomosis for acute type-A aortic dissection surgery.

    Hu, Min / Wang, Jing / Zhou, Yongzhi / Wei, Xiang

    Asian journal of surgery

    2024  Band 47, Heft 5, Seite(n) 2281–2283

    Mesh-Begriff(e) Humans ; Aortic Dissection/surgery ; Suture Techniques ; Anastomosis, Surgical/methods ; Aorta/surgery ; Male ; Acute Disease ; Vascular Surgical Procedures/methods ; Treatment Outcome ; Middle Aged ; Female ; Aortic Aneurysm/surgery
    Sprache Englisch
    Erscheinungsdatum 2024-02-19
    Erscheinungsland Netherlands
    Dokumenttyp Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2024.01.153
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  10. Artikel ; Online: PARP1-DNA co-condensation: the driver of broken DNA repair.

    Wei, Xiang / Zhou, Fangfang / Zhang, Long

    Signal transduction and targeted therapy

    2024  Band 9, Heft 1, Seite(n) 135

    Abstract: DNA double-strand break (DSB) sites that prevent the disjunction of broken DNA ends are formed through poly (ADP-ribose) (PAR) polymerase 1 (PARP1)-DNA co-condensation. The co-condensates apply mechanical forces to hold the DNA ends together and generate ...

    Abstract DNA double-strand break (DSB) sites that prevent the disjunction of broken DNA ends are formed through poly (ADP-ribose) (PAR) polymerase 1 (PARP1)-DNA co-condensation. The co-condensates apply mechanical forces to hold the DNA ends together and generate enzymatic activity for the synthesis of PAR. PARylation can promote the release of PARP1 from DNA ends and recruit various proteins, such as Fused in sarcoma (FUS) proteins, thereby stabilizing broken DNA ends and preventing their separation.
    Mesh-Begriff(e) Humans ; Poly (ADP-Ribose) Polymerase-1/genetics ; Poly (ADP-Ribose) Polymerase-1/metabolism ; DNA Repair/genetics ; DNA Breaks, Double-Stranded ; DNA/genetics ; DNA/metabolism
    Chemische Substanzen PARP1 protein, human
    Sprache Englisch
    Erscheinungsdatum 2024-05-17
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2886872-9
    ISSN 2059-3635 ; 2095-9907
    ISSN (online) 2059-3635
    ISSN 2095-9907
    DOI 10.1038/s41392-024-01832-1
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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