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Article ; Online: Spatiotemporal evolution characteristics and driving forces of vegetation cover variations in the Chengdu-Chongqing region of China under the background of rapid urbanization.

Zhang, Luoqi / Zhang, Yan / Wang, Junyi / Liang, Xinyu / Wei, Yali

Environmental science and pollution research international

2024 Volume 31, Issue 15, Page(s) 22976–22993

Abstract: The research on the spatiotemporal changes and driving factors of ecosystems in rapidly urbanizing regions has always been a topic of widespread concern. As the fourth pole of China's economic development, the research on the Chengdu-Chongqing region has ...

Abstract	The research on the spatiotemporal changes and driving factors of ecosystems in rapidly urbanizing regions has always been a topic of widespread concern. As the fourth pole of China's economic development, the research on the Chengdu-Chongqing region has reference significance for the urbanization process of developing countries such as India, Brazil, and South Africa.The normalized difference vegetation index (NDVI) has been widely applied in studies of plant and ecosystem changes. Based on MODIS NDVI data from 2001 to 2020 and meteorological data of the same period, this study reveals the evolution of NDVI in the Chengdu-Chongqing region from three aspects: the spatiotemporal variation characteristics of NDVI, the prediction of future trends in vegetation coverage, and the response of vegetation to climate change and human activities. During the period of plant growth, the mean NDVI achieved a value of 0.78, and the vegetation coverage rate is increasing year by year. According to the Hurst index, the future NDVI in Chengdu-Chongqing region will tend to decrease, and its trend is opposite to that of the past period of time. The Chengdu-Chongqing region vegetation positively affected by human activities is greater than those negatively affected, and in terms of vegetation degradation, the impact of human activities is greater than climate change.
MeSH term(s)	Humans ; Ecosystem ; Urbanization ; Plant Development ; China ; Climate Change ; Temperature
Language	English
Publishing date	2024-02-28
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-024-32645-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Molecular Mechanisms Behind Vascular Mimicry as the Target for Improved Breast Cancer Management.

Wei, Yali / Jiao, Zheng / Sun, Tianpei / Lai, Zhiwei / Wang, Xiaochun

International journal of women's health

2023 Volume 15, Page(s) 1027–1038

Abstract: Introduction: Breast cancer has a high incidence and mortality rate in women due to metastasis and drug resistance which is associated with vasculogenic mimicry (VM). We purposed to explore VM formulation in breast cancer and mechanism of which is ... ...

Abstract	Introduction: Breast cancer has a high incidence and mortality rate in women due to metastasis and drug resistance which is associated with vasculogenic mimicry (VM). We purposed to explore VM formulation in breast cancer and mechanism of which is involved in EphA2/PIK3R1/CTNNB1 in the present study. Methods: The expression of EphA2/PIK3R1/CTNNB1 and breast cancer patient prognosis was analyzed from TCGA data, both gene and protein expression as well as VM were measured in human breast cancer tissue samples collected in our study. The relationship between EphA2/PIK3R1/CTNNB1 and the formation of VM in breast cancer and its possible regulatory mechanism was explored. Results: The results of the bioinformatics analysis based on TCGA showed that the expression of PIK3R1/ CTNNB1/ PECAM1 (CD31) in tumor tissues was significantly lower than that in normal tissues. EphA2 was positively correlated with PIK3R1, PIK3R1 with CTNNB1, and CTNNB1 with PECAM1 expression in breast cancer tissues. The results of detection in breast cancer and adjacent tissues indicated that the expression of EphA2/PIK3R1/CTNNB1 in cancer tissues was significantly lower than that in adjacent tissues. The expression of PIK3R1 was positively correlated with EphA2 and CTNNB1 expression, respectively, as well as EphA2 expression correlated with CTNNB1 expression positively. VM formation was significantly increased in breast cancer tissues compared with adjacent tissues. Conclusion: Our results suggested that the formation of VM in breast cancer may be related to the EphA2/PIK3R1/CTNNB1 molecular signaling pathway.
Language	English
Publishing date	2023-07-12
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2508161-5
ISSN	1179-1411
ISSN	1179-1411
DOI	10.2147/IJWH.S406327
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Article ; Online: Microbial community and functional prediction during the processing of salt production in a 1000-year-old marine solar saltern of South China.

Wei, Ya-Li / Long, Zi-Jie / Ren, Ming-Xun

The Science of the total environment

2021 Volume 819, Page(s) 152014

Abstract: In Hainan Island, South China, a 1000-year-old marine saltern has been identified as an intangible cultural heritage due to its historical complicated salt-making techniques, whereas the knowledge about this saltern is extremely limited. Herein, DNA ... ...

Abstract	In Hainan Island, South China, a 1000-year-old marine saltern has been identified as an intangible cultural heritage due to its historical complicated salt-making techniques, whereas the knowledge about this saltern is extremely limited. Herein, DNA sequencing and biochemical technologies were applied to determine bacterial and fungal communities of this saltern and their possible functions during four stages of salt-making, i.e. seawater storage, mud solarization, brine concentrating, and solar crystallization. The results showed that both of bacterial and fungal communities were suffered from significant changes during processing of salt-making in Danzhou Ancient Saltern, whereas the richness and diversity of bacterial community dominated by Proteobacteria, Bacteroidota and Cyanobacteria was considerably greater than that of fungal community dominated by Ascomycota, Basidiomycota and Mortierellomycota. Additionally, the succession of bacterial community was closely associated with both of salt physicochemical properties (Na
MeSH term(s)	Ascomycota ; Bacteria ; China ; Fungi/genetics ; Microbiota ; Mycobiome ; Seawater/microbiology
Language	English
Publishing date	2021-11-28
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2021.152014
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Article: Wheat powdery mildew resistance: from gene identification to immunity deployment.

Zou, Shenghao / Xu, Yang / Li, Qianqian / Wei, Yali / Zhang, Youlian / Tang, Dingzhong

Frontiers in plant science

2023 Volume 14, Page(s) 1269498

Abstract: Powdery mildew is one of the most devastating diseases on wheat and is caused by the obligate biotrophic ... ...

Abstract	Powdery mildew is one of the most devastating diseases on wheat and is caused by the obligate biotrophic phytopathogen
Language	English
Publishing date	2023-09-18
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2613694-6
ISSN	1664-462X
ISSN	1664-462X
DOI	10.3389/fpls.2023.1269498
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Article: Evaluation of Atlas-Based Mobile Application in Undergraduate Teaching in Oral Histopathology.

Deng, Shuangshan / Li, Zucen / Ma, Xinyu / Wei, Yali / Lyu, Ping / Fan, Yi

Healthcare (Basel, Switzerland)

2023 Volume 11, Issue 14

Abstract: The utilization of mobile devices in education is a growing trend in various subjects. We developed the Dental and Maxillofacial Development Teaching Atlas App, and applied it to the learning process of oral histopathology. The aim of the current study ... ...

Abstract	The utilization of mobile devices in education is a growing trend in various subjects. We developed the Dental and Maxillofacial Development Teaching Atlas App, and applied it to the learning process of oral histopathology. The aim of the current study was to investigate the educational effects of atlas-based mobile-assisted teaching in the field of dental medicine, and to suggest relevant improvements. The Dental and Maxillofacial Development Teaching Atlas App encompasses a wide range of atlases. It harbors various features, such as terminology definitions, student communications, and teacher-student interactions. By conducting questionnaires (70 students) and a quiz (68 students), we obtained students' feedback, to evaluate the effects and application prospects of the WeChat applet. The questionnaire results indicate that students experienced a high level of satisfaction and support. Additionally, students participated in the quiz, with the experimental group exhibiting significantly higher average scores than the control group. The fill-in-the-blank questions, image recognition questions, and the total score all demonstrated statistically significant differences, while the terminology definition questions did not. The Dental and Maxillofacial Development Teaching Atlas App facilitates students' utilization of fragmented time for learning, and demonstrates positive effects in enhancing students' learning interests and proactiveness. It also holds promising potential for applications in other disciplines in the field of dental education.
Language	English
Publishing date	2023-07-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2721009-1
ISSN	2227-9032
ISSN	2227-9032
DOI	10.3390/healthcare11142087
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Article ; Online: GmFLS2 contributes to soybean resistance to Ralstonia solanacearum.

Chen, Yujiao / Zhao, Achen / Wei, Yali / Mao, Yanfei / Zhu, Jian-Kang / Macho, Alberto P

The New phytologist

2023 Volume 240, Issue 1, Page(s) 17–22

MeSH term(s)	Ralstonia solanacearum ; Glycine max ; Virulence ; Plant Diseases
Language	English
Publishing date	2023-06-30
Publishing country	England
Document type	Letter ; Research Support, Non-U.S. Gov't
ZDB-ID	208885-x
ISSN	1469-8137 ; 0028-646X
ISSN (online)	1469-8137
ISSN	0028-646X
DOI	10.1111/nph.19111
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Bioequivalence and Safety Assessment of 2 Formulations of Low-Dose Metformin Hydrochloride under Fasting Conditions in Healthy Chinese Participants: A Randomized Phase 1 Clinical Trial.

Sun, Ming-Li / Xu, Xin-Wen / Liu, Chen / Tong, Yuan-Xu / Wei, Ya-Li / Liu, Hui-Juan / Zhang, Wei / Wang, Xing-He

Clinical pharmacology in drug development

2024 Volume 13, Issue 3, Page(s) 307–314

Abstract: The incidence of type 2 diabetes is high, and the existing metformin hydrochloride (MH) tablets of 250 mg cannot meet the demands of the Chinese drug market. This study aimed to evaluate the bioequivalence and safety of generic formulations of MH tablets ...

Abstract	The incidence of type 2 diabetes is high, and the existing metformin hydrochloride (MH) tablets of 250 mg cannot meet the demands of the Chinese drug market. This study aimed to evaluate the bioequivalence and safety of generic formulations of MH tablets (test formulation [T], 250 mg/tablet) and innovative products (reference formulation [R], 250 mg/tablet) under fasting conditions. This was an open-label, single-dose, 2-period, 2-sequence crossover, single-center, randomized phase I clinical trial. T and R were considered bioequivalent if the adjusted geometric mean ratios (GMRs) and 90% confidence intervals of the area under the curve (AUC) and maximum concentration (C
MeSH term(s)	Humans ; Therapeutic Equivalency ; Metformin/adverse effects ; Diabetes Mellitus, Type 2/drug therapy ; Fasting ; Tablets ; China
Chemical Substances	Metformin (9100L32L2N) ; Tablets
Language	English
Publishing date	2024-01-08
Publishing country	United States
Document type	Randomized Controlled Trial ; Clinical Trial, Phase I ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2649010-9
ISSN	2160-7648 ; 2160-763X
ISSN (online)	2160-7648
ISSN	2160-763X
DOI	10.1002/cpdd.1369
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Article: Spatial-Temporal Evolution Characteristics and Driving Force Analysis of NDVI in the Minjiang River Basin, China, from 2001 to 2020

Wang, Junyi / Fan, Yifei / Yang, Yu / Zhang, Luoqi / Zhang, Yan / Li, Shixiang / Wei, Yali

Water. 2022 Sept. 18, v. 14, no. 18

2022

Abstract: Monitoring vegetation growth and exploring the driving force behind it is very important for the study of global climate change and ecological environmental protection. Based on Normalized Difference Vegetation Index (NDVI) data from Moderate-Resolution ... ...

Abstract	Monitoring vegetation growth and exploring the driving force behind it is very important for the study of global climate change and ecological environmental protection. Based on Normalized Difference Vegetation Index (NDVI) data from Moderate-Resolution Imaging Spectroradiometer (MODIS), meteorological and nighttime lights data from 2001 to 2020, this study uses the Theil–Sen slope test, Mann–Kendall significance test, Rescaled Range Analysis and partial correlation analysis to investigate the evolution of NDVI in the Minjiang River Basin, China, from three aspects: the spatial-temporal variation characteristics and future trend prediction of NDVI, the variation of climate and human activities in the basin, and the influences of different driving forces on NDVI. The results show that the average NDVI in the growing season was 0.60 in the Minjiang River Basin in the past twenty years, with a growth rate of 0.002/a. The area with high NDVI growth accounts for 66.02%, mainly distributed in the southeast, the central and the northern low-altitude areas of the basin. Combined with the Hurst index, the NDVI in the Minjiang River Basin exhibits an anti-sustainable tendency, with 63.22% of the area changing from improvement to degradation in the future. Meanwhile, the spatial differentiation of NDVI in the Minjiang River Basin is mainly affected by topography and climate factors, followed by human activities. This study not only provides scientific guidelines for the vegetation restoration, soil and water conservation and sustainable development of the Minjiang River Basin, but also provides a scientific basis for making informed decisions on ecological protection under the impacts of climate change and human activities.
Keywords	altitude ; basins ; climate ; climate change ; ecological restoration ; evolution ; humans ; normalized difference vegetation index ; prediction ; soil ; spatial variation ; spectroradiometers ; sustainable development ; vegetation ; water ; water conservation ; watersheds ; China
Language	English
Dates of publication	2022-0918
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2521238-2
ISSN	2073-4441
ISSN	2073-4441
DOI	10.3390/w14182923
Database	NAL-Catalogue (AGRICOLA)

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Article: The Effects of Resistant Starch on Biomarkers of Inflammation and Oxidative Stress: A Systematic Review and Meta-Analysis

Wei, Yali / Zhang, Xiyu / Meng, Yan / Wang, Qian / Xu, Hongzhao / Chen, Liyong

Nutrition and cancer. 2022 June 30, v. 74, no. 7

2022

Abstract: The aim of this systematic review and meta-analysis was to investigate the effects of resistant starch (RS) on inflammation and oxidative stress related indicators. PubMed, Embase and The Cochrane library were systematically searched to find randomized ... ...

Abstract	The aim of this systematic review and meta-analysis was to investigate the effects of resistant starch (RS) on inflammation and oxidative stress related indicators. PubMed, Embase and The Cochrane library were systematically searched to find randomized controlled trials (RCTs) of RS intervention up to February 2020. We used from the effect size, as estimated by the standardized mean difference (SMD) with 95% confidence intervals (95%CI) to perform the random method meta-analysis, with P value ≦0.05 as statistically significant. The 16 included trials with 17 effect sizes included a total of 739 participants in this paper. The intervention duration was from 2 weeks to 3 months. The analysis indicated that RS decreases the levels of tumor necrosis factor-α (TNF‐α) (SMD = −0.711; 95%CI: −1.227, −0.194; P = 0.007) and interleukin 6 (IL‐6) (SMD = −0.609; 95%CI: −0.924, −0.294; P < 0.001), increases total antioxidant capacity (TAC) (SMD = 2.543, 95% CI: 0.069: 5.017, P = 0.044). No significant effects on C‐reactive protein (CRP) (SMD = −0.583; 95%CI: −1.270, 0.104; P = 0.096), superoxide dismutase (SOD) (SMD = 0.091; 95%CI: −0.156, 0.338; P = 0.471), and malondialdehyde (MDA) (SMD = −0.320; 95%CI: −0.907, 0.266; P = 0.285). Subgroup analysis shown that CRP level significant reduced in subjects from the east (SMD = −1.501; 95%CI: −2.662, −0.340; P = 0.011) or suffering from diseases (SMD: −1.057; 95%CI: −1.999, −0.115; P = 0.028). Supplemental data for this article is available online at https://doi.org/10.1080/01635581.2021.2019284
Keywords	C-reactive protein ; antioxidant activity ; biomarkers ; inflammation ; interleukin-6 ; malondialdehyde ; meta-analysis ; necrosis ; neoplasms ; nutrition ; oxidative stress ; resistant starch ; superoxide dismutase ; systematic review
Language	English
Dates of publication	2022-0630
Size	p. 2337-2350.
Publishing place	Taylor & Francis
Document type	Article
ZDB-ID	424433-3
ISSN	1532-7914 ; 0163-5581
ISSN (online)	1532-7914
ISSN	0163-5581
DOI	10.1080/01635581.2021.2019284
Database	NAL-Catalogue (AGRICOLA)

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Zs.A 1496: Show issues

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ab Jg. 2022: Lesesaal (EG)

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Article: Diversity and importance of culturable endophytic fungi of tobacco (Nicotinana tabacum) cultivated in southwestern China

Wang, Maosheng / Sun, Jialong / Wei, Yali / Jia, Yanlong / Zou, Xiao

Phytopathologische Zeitschrift. 2022 Sept., v. 170, no. 9

2022

Abstract: Tobacco (Nicotiana tabacum) is one of the most important economic crops in China; however, black shank caused by Phytophthora parasitica is major threat to its cultivation. So far, little is known regarding potential antagonistic effects of endophytes on ...

Abstract	Tobacco (Nicotiana tabacum) is one of the most important economic crops in China; however, black shank caused by Phytophthora parasitica is major threat to its cultivation. So far, little is known regarding potential antagonistic effects of endophytes on plant pathogens. A total of 109 culturable endophytic fungal strains were recovered from various tissues of six tobacco cultivars that are commonly cultivated in southwestern China. Morphological and molecular identification showed that these isolates belonged to 18 different genera, including Aspergillus, Chaetomium, Gibellulopsis and Penicillium as predominant genera, which were frequently observed in stem, leaf and root tissues. Among them, only 17 endophytic fungal strains exerted antagonistic effects on P. parasitica in the dual‐culture test, and the highest inhibition rate of 73% was produced by a Penicillium janthinellum strain isolated from stem tissue of a cultivar HD. Nevertheless, a field trial revealed that Shannon–Wiener indices were negatively correlated with the disease index and with the incidence of tobacco blank shank in cultivars K326, YUN85, D101 and GUI1, which was further supported by the evaluation of endophytic community similarity. Our results contribute to the understanding of functions and diversity of endophytic fungi, and culturable endophytic fungal strains may be considered potential libraries for screening novel bioactive and effective metabolites to control P. parasitica in crops which requires further research.
Keywords	Aspergillus ; Chaetomium ; Gibellulopsis ; Nicotiana tabacum ; Penicillium janthinellum ; Phytophthora nicotianae var. parasitica ; cultivars ; endophytes ; field experimentation ; fungi ; leaves ; metabolites ; tobacco ; China
Language	English
Dates of publication	2022-09
Size	p. 614-625.
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	633487-8
ISSN	0931-1785
ISSN	0931-1785
DOI	10.1111/jph.13126
Database	NAL-Catalogue (AGRICOLA)

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