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Article ; Online: Mapping the Landscape of Obesity Effects on Male Reproductive Function: A Bibliometric Study.

Wei, Yanhong / Liao, Meihua / Lu, Yiming / Lei, Xiaocan / Wang, Junli / Hu, Linlin / Luo, Xiaoqiong

Endocrine, metabolic & immune disorders drug targets

2024

Abstract: Background: Due to changes in lifestyle and dietary habits, the global population with obesity is increasing gradually, resulting in a significant rise in the number of individuals having obesity. Obesity is caused by an imbalance between energy intake ... ...

Abstract	Background: Due to changes in lifestyle and dietary habits, the global population with obesity is increasing gradually, resulting in a significant rise in the number of individuals having obesity. Obesity is caused by an imbalance between energy intake and consumption, leading to excessive fat accumulation, which interferes with normal human metabolism. It is also associated with cardiovascular disease, metabolic syndrome, male reproductive endocrine regulation disorders, systemic and local inflammatory reactions, excessive oxidative stress, and apoptosis. All these factors can damage the internal environment for sperm generation and maturation, resulting in male sexual dysfunction, a decline in sperm quality, and lower fertility. This study analyzes the trends and priorities of the effects of obesity on male reproductive disorders from a bibliometric perspective. Methods: This study uses the Web of Science as the statistical source, covering all time spans. Tools like Web of Science, VOSviewer, and CiteSpace are used to analyze countries, institutions, authors, journals, and keywords in the field. Total publications, total citations, and average number of citations are selected for statistics. Results: The results show that the research on the impact of obesity on male reproductive function can be roughly divided into three stages: the initial stage, the slow development stage, and the rapid development stage. Our statistical scope includes 463 highly relevant articles that we have screened. We found that the journal with the most publications in this field is Andrologia, and the institution with the highest total citations is the University of Utah. The most influential countries, institutions, and authors in this field are the United States, the University of Utah, and Carrell, Douglas. Currently, research related to the impact of obesity on male reproduction focuses mainly on three aspects: biochemistry, molecular biology, and reproductive biology. The keyword explosion results indicate that sperm, obesity, and male reproduction are at the forefront and trends of future research in this field. There has been a shift from basic biochemical and molecular research to research on molecular mechanisms relying on omics technologies. However, we have observed that the number of papers published in 2022 is lower than in 2021, indicating a growth interruption during this period. Considering that this deviation may be due to the impact of the COVID-19 pandemic, it may hinder the progress of certain experiments in 2022. In recent years, China has rapidly developed research in this field. However, the average citation rate is relatively low, indicating the need for Chinese scholars to improve the quality of their articles further. Based on our research and in the context of global obesity, men are at risk of increased infertility. Addressing this issue relies on our continued research into the mechanisms of obesity-related male reproductive disorders. Over the past forty-three years, with the contributions of scientists worldwide, research in this field has flourished. Conclusion: The impact of obesity on male reproductive disorders has been extensively studied. Currently, research in this field primarily focuses on male sperm function, sperm quality, and the effects or mechanisms of cells on male reproduction. Future trends in this field should concentrate on the relationship between male fertility and energy metabolism, as well as the endocrine function of adipose tissue. This study comprehensively analyzes the current research status and global trends in obesity and male reproductive disorders. We also discuss the future developments in this field, making it easier for researchers to understand its developmental history, current status, and trends, providing valuable reference for effective exploration in this area.
Language	English
Publishing date	2024-01-30
Publishing country	United Arab Emirates
Document type	Journal Article
ZDB-ID	2228325-0
ISSN	2212-3873 ; 1871-5303
ISSN (online)	2212-3873
ISSN	1871-5303
DOI	10.2174/0118715303271117231220072051
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Article ; Online: High Dose of Estrogen Protects the Lungs from Ischemia-Reperfusion Injury by Downregulating the Angiotensin II Signaling Pathway.

Dai, Peng / He, Jutong / Wei, Yanhong / Xu, Ming / Zhao, Jinping / Zhou, Xuefeng / Tang, Hexiao

Inflammation

2024

Abstract: We explored the sex difference in lung ischemia-reperfusion injury (LIRI) and the role and mechanism of estrogen (E2) and angiotensin II (Ang II) in LIRI. We established a model of LIRI in mice. E2, Ang II, E2 inhibitor (fulvestrant), and angiotensin II ... ...

Abstract	We explored the sex difference in lung ischemia-reperfusion injury (LIRI) and the role and mechanism of estrogen (E2) and angiotensin II (Ang II) in LIRI. We established a model of LIRI in mice. E2, Ang II, E2 inhibitor (fulvestrant), and angiotensin II receptor blocker (losartan) were grouped for treatment. The lung wet/dry weight ratio, natural killer (NK) cells (by flow cytometry), neutrophils (by flow cytometry), expression of key proteins (by Western blot, immunohistochemistry, ELISA, and immunofluorescence), and expression of related protein mRNA (by qPCR) were detected. The ultrastructure of the alveolar epithelial cells was observed by transmission electron microscopy. We found that E2 and Ang II played an important role in the progression of LIRI. The two signaling pathways showed obvious antagonism, and E2 regulates LIRI in the different sexes by downregulating Ang II, leading to a better prognosis. E2 and losartan reduced the inflammatory cell infiltration in lung tissue and key inflammatory factors in serum while fulvestrant and Ang II had the opposite effect. The protective effect of E2 was related with AKT, p38, COX2, and HIF-1α.
Language	English
Publishing date	2024-02-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	434408-x
ISSN	1573-2576 ; 0360-3997
ISSN (online)	1573-2576
ISSN	0360-3997
DOI	10.1007/s10753-024-01973-z
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Article: Evolution of historical sediment yield using check-dam systems as carriers: A case study in a restored agricultural catchment on the Loess Plateau, China

Wei, Yanhong / Jiao, Juying / Li, Yujin

Catena. 2022 Mar., v. 210

2022

Abstract: It is critical to determine soil erosion rates and sediment yields under ecological restoration conditions on the Loess Plateau. Sediments retained in check-dams document the soil erosion history in a small watershed. We selected the check-dam systems to ...

Abstract	It is critical to determine soil erosion rates and sediment yields under ecological restoration conditions on the Loess Plateau. Sediments retained in check-dams document the soil erosion history in a small watershed. We selected the check-dam systems to reconstruct the long-term sediment yield in a restored agricultural catchment on the Loess Plateau. The storage capacity curve method was applied to estimate the total sediment deposition of check-dam systems, and 725.82 thousand tons of sediment was trapped in the check-dams systems from 1975 to 2013. Two abrupt change points were detected in 1987 and 2003 using the double mass curve method; the average catchment sediment yields were 5,273.63 t/(km²·a) in Stage-1 (1975–1987), 1,734.09 t/(km²·a) in Stage-2 (1988–2003), and 2,653.10 t/(km²·a) in Stage-3 (2004–2013), represented intense erosion, mild erosion, and moderate erosion, respectively. In Stage-2, the sediment yield variation in the Fangta catchment was mainly affected by human activities, and its contribution reached 97%. According to the hierarchical cluster analysis, the soil erosion intensity changed gradually from mild to moderate and then to intense when the average annual erosive rainfall reached approximately 300, 350, and 400 mm in the Fangta catchment of the loess hilly-gully region. Approximately 6.1–42.6 % of the sediment was deposited along the way since 2003 when the sediments generated by erosion in small watersheds were gradually transported to the downstream river network. Therefore, check-dam systems are important carriers for reconstructing the historical sediment yield in small and ungauged watersheds. The results of this study not only serve as a basis for obtaining reliable information on erosion and sediment yield in small dam-controlled catchments, but also provide a useful reference for implementing sustainable ecological restoration in the future.
Keywords	agricultural watersheds ; case studies ; catenas ; cluster analysis ; ecological restoration ; evolution ; humans ; loess ; rain ; rivers ; sediment deposition ; sediment yield ; soil erosion ; China
Language	English
Dates of publication	2022-03
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	519608-5
ISSN	1872-6887 ; 0008-7769 ; 0341-8162
ISSN (online)	1872-6887 ; 0008-7769
ISSN	0341-8162
DOI	10.1016/j.catena.2021.105877
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Inflammasomes during SARS-CoV-2 infection and development of their corresponding inhibitors.

Diarimalala, Rominah Onintsoa / Wei, Yanhong / Hu, Da / Hu, Kanghong

Frontiers in cellular and infection microbiology

2023 Volume 13, Page(s) 1218039

Abstract: Corona Virus Disease 2019 (COVID-19) continues to be a burden for human health since its outbreak in Wuhan, China in December 2019. Recently, the emergence of new variants of concerns (VOCs) is challenging for vaccines and drugs efficiency. In severe ... ...

Abstract	Corona Virus Disease 2019 (COVID-19) continues to be a burden for human health since its outbreak in Wuhan, China in December 2019. Recently, the emergence of new variants of concerns (VOCs) is challenging for vaccines and drugs efficiency. In severe cases, SARS-CoV-2 provokes inappropriate hyperinflammatory immune responses leading to acute respiratory distress syndrome (ARDS) and even death. This process is regulated by inflammasomes which are activated after binding of the viral spike (S) protein to cellular angiotensin-converting enzyme 2 (ACE2) receptor and triggers innate immune responses. Therefore, the formation of "cytokines storm" leads to tissue damage and organ failure. NOD-like receptor family pyrin domain containing 3 (NLRP3) is the best studied inflammasome known to be activated during SARS-CoV-2 infection. However, some studies suggest that SARS-CoV-2 infection is associated with other inflammasomes as well; such as NLRP1, absent in melanoma-2 (AIM-2), caspase-4 and -8 which were mostly found during dsRNA virus or bacteria infection. Multiple inflammasome inhibitors that exist for other non-infectious diseases have the potential to be used to treat severe SARS-CoV-2 complications. Some of them have showed quite encouraging results during pre- and clinical trials. Nevertheless, further studies are in need for the understanding and targeting of SARS-Cov-2-induced inflammasomes; mostly an update of its role during the new VOCs infection is necessary. Hence, this review highlights all reported inflammasomes involved in SARS-CoV-2 infection and their potential inhibitors including NLRP3- and Gasdermin D (GSDMD)-inhibitors. Further strategies such as immunomodulators and siRNA are also discussed. As highly related to COVID-19 severe cases, developing inflammasome inhibitors holds a promise to treat severe COVID-19 syndrome effectively and reduce mortality.
MeSH term(s)	Humans ; Inflammasomes/metabolism ; COVID-19 ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; SARS-CoV-2/physiology ; Cytokines/metabolism
Chemical Substances	Inflammasomes ; NLR Family, Pyrin Domain-Containing 3 Protein ; Cytokines
Language	English
Publishing date	2023-06-09
Publishing country	Switzerland
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2619676-1
ISSN	2235-2988 ; 2235-2988
ISSN (online)	2235-2988
ISSN	2235-2988
DOI	10.3389/fcimb.2023.1218039
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Article ; Online: Legume-Derived Bioactive Peptides in Type 2 Diabetes: Opportunities and Challenges.

Hu, Kanghong / Huang, Huizhong / Li, Hanluo / Wei, Yanhong / Yao, Chenguang

Nutrients

2023 Volume 15, Issue 5

Abstract: Diabetes mellitus is a complex disorder characterized by insufficient insulin production or insulin resistance, which results in a lifelong dependence on glucose-lowering drugs for almost all patients. During the fight with diabetes, researchers are ... ...

Abstract	Diabetes mellitus is a complex disorder characterized by insufficient insulin production or insulin resistance, which results in a lifelong dependence on glucose-lowering drugs for almost all patients. During the fight with diabetes, researchers are always thinking about what characteristics the ideal hypoglycemic drugs should have. From the point of view of the drugs, they should maintain effective control of blood sugar, have a very low risk of hypoglycemia, not increase or decrease body weight, improve β-cell function, and delay disease progression. Recently, the advent of oral peptide drugs, such as semaglutide, brings exciting hope to patients with chronic diabetes. Legumes, as an excellent source of protein, peptides, and phytochemicals, have played significant roles in human health throughout human history. Some legume-derived peptides with encouraging anti-diabetic potential have been gradually reported over the last two decades. Their hypoglycemic mechanisms have also been clarified at some classic diabetes treatment targets, such as the insulin receptor signaling pathway or other related pathways involved in the progress of diabetes, and key enzymes including α-amylase, α-glucosidase, and dipeptidyl peptidase-IV (DPP-4). This review summarizes the anti-diabetic activities and mechanisms of peptides from legumes and discusses the prospects of these peptide-based drugs in type 2 diabetes (T2D) management.
MeSH term(s)	Humans ; Diabetes Mellitus, Type 2 ; Fabaceae ; Dipeptidyl-Peptidase IV Inhibitors/chemistry ; Hypoglycemic Agents/therapeutic use ; Peptides/chemistry
Chemical Substances	Dipeptidyl-Peptidase IV Inhibitors ; Hypoglycemic Agents ; Peptides
Language	English
Publishing date	2023-02-22
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15051096
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Article ; Online: Bacterial diversity in primary infected root canals of a Chinese cohort: analysis of 16 S rDNA sequencing.

Hu, Ziqiu / Xiang, Yonggang / Wei, Yanhong / Gu, Xinsheng / Leng, Weidong / Xia, Lingyun

BMC oral health

2023 Volume 23, Issue 1, Page(s) 932

Abstract: Purpose: To characterize the bacterial community in the primarily infected root canals.: Methods: A total of 13 samples were collected from the primarily infected root canals. 16 S rDNA sequencing was performed to define bacterial community. ... ...

Abstract	Purpose: To characterize the bacterial community in the primarily infected root canals. Methods: A total of 13 samples were collected from the primarily infected root canals. 16 S rDNA sequencing was performed to define bacterial community. Taxonomic annotation, bacterial hierarchical structures, community richness and diversity, and inter-subject variability of the bacterial community in the root canal samples were analyzed. Gender, age, and duration of the toothache-specific bacterial community associated with the patient groups were analyzed. Results: A total of 359 Species were annotated and identified in the whole study cohort. The Alpha diversity analysis showed that the species diversity and detection rate of the 13 samples were high, which reflected the authenticity of sequencing results. The Beta diversity analysis was used to compare the degree of difference between different root canal samples. The 13 samples were divided into two groups according to the results, group A was samples I1-I12, and group B was samples I13. The bacterial species of group A samples were analyzed with the clinical characteristics of patients, and it was found that gender, and duration specific differences in bacterial species, and there was no significant difference in species types among different ages of patients. Conclusion: There were a wide diversity and inter-subject variability in the bacterial community in the primary infected root canals. While Porphyromonas gingivalis was the most abundant species, Fusobacterium nucleatum was the most variable species in the bacterial community of the root canal. The bacterial community at different taxonomic levels varied from sample to sample, despite consistent disease diagnoses. There was gender, duration-specific differences in the bacterial species in the primary infected root canals.
MeSH term(s)	Humans ; Dental Pulp Cavity/microbiology ; East Asian People ; Fusobacterium nucleatum/genetics ; Fusobacterium nucleatum/isolation & purification ; Periapical Periodontitis/microbiology ; Porphyromonas gingivalis/genetics ; Porphyromonas gingivalis/isolation & purification ; Root Canal Therapy ; DNA, Ribosomal
Chemical Substances	DNA, Ribosomal
Language	English
Publishing date	2023-11-27
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2091511-1
ISSN	1472-6831 ; 1472-6831
ISSN (online)	1472-6831
ISSN	1472-6831
DOI	10.1186/s12903-023-03618-3
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Article ; Online: EV-A71 Mechanism of Entry: Receptors/Co-Receptors, Related Pathways and Inhibitors.

Hu, Kanghong / Onintsoa Diarimalala, Rominah / Yao, Chenguang / Li, Hanluo / Wei, Yanhong

Viruses

2023 Volume 15, Issue 3

Abstract: Enterovirus A71, a non-enveloped single-stranded (+) RNA virus, enters host cells through three stages: attachment, endocytosis and uncoating. In recent years, receptors/co-receptors anchored on the host cell membrane and involved in this process have ... ...

Abstract	Enterovirus A71, a non-enveloped single-stranded (+) RNA virus, enters host cells through three stages: attachment, endocytosis and uncoating. In recent years, receptors/co-receptors anchored on the host cell membrane and involved in this process have been continuously identified. Among these, hSCARB-2 was the first receptor revealed to specifically bind to a definite site of the EV-A71 viral capsid and plays an indispensable role during viral entry. It actually acts as the main receptor due to its ability to recognize all EV-A71 strains. In addition, PSGL-1 is the second EV-A71 receptor discovered. Unlike hSCARB-2, PSGL-1 binding is strain-specific; only 20% of EV-A71 strains isolated to date are able to recognize and bind it. Some other receptors, such as sialylated glycan, Anx 2, HS, HSP90, vimentin, nucleolin and fibronectin, were discovered successively and considered as "co-receptors" because, without hSCARB-2 or PSGL-1, they are not able to mediate entry. For cypA, prohibitin and hWARS, whether they belong to the category of receptors or of co-receptors still needs further investigation. In fact, they have shown to exhibit an hSCARB-2-independent entry. All this information has gradually enriched our knowledge of EV-A71's early stages of infection. In addition to the availability of receptors/co-receptors for EV-A71 on host cells, the complex interaction between the virus and host proteins and various intracellular signaling pathways that are intricately connected to each other is critical for a successful EV-A71 invasion and for escaping the attack of the immune system. However, a lot remains unknown about the EV-A71 entry process. Nevertheless, researchers have been continuously interested in developing EV-A71 entry inhibitors, as this study area offers a large number of targets. To date, important progress has been made toward the development of several inhibitors targeting: receptors/co-receptors, including their soluble forms and chemically designed compounds; virus capsids, such as capsid inhibitors designed on the VP1 capsid; compounds potentially interfering with related signaling pathways, such as MAPK-, IFN- and ATR-inhibitors; and other strategies, such as siRNA and monoclonal antibodies targeting entry. The present review summarizes these latest studies, which are undoubtedly of great significance in developing a novel therapeutic approach against EV-A71.
MeSH term(s)	Humans ; Enterovirus A, Human/genetics ; Enterovirus/metabolism ; Enterovirus Infections ; Capsid Proteins/genetics ; Capsid/metabolism
Chemical Substances	Capsid Proteins
Language	English
Publishing date	2023-03-18
Publishing country	Switzerland
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2516098-9
ISSN	1999-4915 ; 1999-4915
ISSN (online)	1999-4915
ISSN	1999-4915
DOI	10.3390/v15030785
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Article ; Online: Efficacy of antioxidant supplementation in improving endocrine, hormonal, inflammatory, and metabolic statuses of PCOS: a meta-analysis and systematic review.

He, Junhui / Deng, Renhe / Wei, Yanhong / Zhang, Shun / Su, Mingxuan / Tang, Masong / Wang, Jinyuan / Nong, Weihua / Lei, Xiaocan

Food & function

2024 Volume 15, Issue 4, Page(s) 1779–1802

Abstract: Background and ... ...

Abstract	Background and aim
MeSH term(s)	Female ; Humans ; Antioxidants/therapeutic use ; Polycystic Ovary Syndrome/drug therapy ; Polycystic Ovary Syndrome/metabolism ; Dietary Supplements ; Lipoproteins, LDL ; Cholesterol
Chemical Substances	Antioxidants ; Lipoproteins, LDL ; Cholesterol (97C5T2UQ7J)
Language	English
Publishing date	2024-02-19
Publishing country	England
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	2612033-1
ISSN	2042-650X ; 2042-6496
ISSN (online)	2042-650X
ISSN	2042-6496
DOI	10.1039/d3fo02824k
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Article ; Online: A pancancer analysis of the oncogenic role of cyclin B1 (CCNB1) in human tumors.

Dai, Peng / Xiong, Lecai / Wei, Yanhong / Wei, Xiaoyan / Zhou, Xuefeng / Zhao, Jinping / Tang, Hexiao

Scientific reports

2023 Volume 13, Issue 1, Page(s) 16226

Abstract: Aberrant levels of the G2/M cyclin cyclin B1 (gene CCNB1) have been associated with multiple cancers; however, the literature lacks a focused and comprehensive analysis of the regulation of this important regulator of cell proliferation in cancer. ... ...

Abstract	Aberrant levels of the G2/M cyclin cyclin B1 (gene CCNB1) have been associated with multiple cancers; however, the literature lacks a focused and comprehensive analysis of the regulation of this important regulator of cell proliferation in cancer. Through this work, we performed a pancancer analysis of the levels of CCNB1 and dissected aspects of regulation and how this correlates with cancer prognosis. We comprehensively evaluated the expression and promoter methylation of CCNB1 across 38 cancers based on RNA sequencing data obtained from the Cancer Genome Atlas (TCGA). The correlation of CCNB1 with prognosis and the tumor microenvironment was explored. Using lung adenocarcinoma data, we studied the potential upstream noncoding RNAs involved in the regulation of CCNB1 and validated the protein levels and prognostic value of CCNB1 for this disease site. CCNB1 was highly expressed, and promoter methylation was reduced in most cancers. Gene expression of CCNB1 correlated positively with poor prognosis of tumor patients, and these results were confirmed at the protein level using lung adenocarcinoma. CCNB1 expression was associated with the infiltration of T helper cells, and this further correlated with poor prognosis for certain cancers, including renal clear cell carcinoma and lung adenocarcinoma. Subsequently, we identified a specific upstream noncoding RNA contributing to CCNB1 overexpression in lung adenocarcinoma through correlation analysis, expression analysis and survival analysis. This study provides a comprehensive analysis of the expression and methylation status of CCNB1 across several forms of cancer and provides further insight into the mechanistic pathways regulating Cyclin B1 in the tumorigenesis process.
MeSH term(s)	Humans ; Adenocarcinoma of Lung/genetics ; Cell Line, Tumor ; Cell Transformation, Neoplastic/genetics ; Cyclin B1/genetics ; Cyclin B1/metabolism ; Gene Expression Regulation, Neoplastic ; Prognosis ; Survival Analysis ; Tumor Microenvironment
Chemical Substances	CCNB1 protein, human ; Cyclin B1
Language	English
Publishing date	2023-09-27
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-42801-y
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Article ; Online: Investigating the Nexus of NLRP3 Inflammasomes and COVID-19 Pathogenesis: Unraveling Molecular Triggers and Therapeutic Strategies.

He, Qun / Hu, Da / Zheng, Fuqiang / Chen, Wenxuan / Hu, Kanghong / Liu, Jinbiao / Yao, Chenguang / Li, Hanluo / Wei, Yanhong

Viruses

2024 Volume 16, Issue 2

Abstract: The coronavirus disease 2019 (COVID-19) global pandemic, caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), has been marked by severe cases demonstrating a "cytokine storm", an upsurge of pro-inflammatory cytokines in the ... ...

Abstract	The coronavirus disease 2019 (COVID-19) global pandemic, caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), has been marked by severe cases demonstrating a "cytokine storm", an upsurge of pro-inflammatory cytokines in the bloodstream. NLRP3 inflammasomes, integral to the innate immune system, are speculated to be activated by SARS-CoV-2 within host cells. This review investigates the potential correlation between NLRP3 inflammasomes and COVID-19, exploring the cellular and molecular mechanisms through which SARS-CoV-2 triggers their activation. Furthermore, promising strategies targeting NLRP3 inflammasomes are proposed to mitigate the excessive inflammatory response provoked by SARS-CoV-2 infection. By synthesizing existing studies, this paper offers insights into NLRP3 as a therapeutic target, elucidating the interplay between COVID-19 and its pathophysiology. It serves as a valuable reference for future clinical approaches in addressing COVID-19 by targeting NLRP3, thus providing potential avenues for therapeutic intervention.
MeSH term(s)	Humans ; COVID-19 ; Cytokines ; Inflammasomes ; NLR Family, Pyrin Domain-Containing 3 Protein ; SARS-CoV-2/physiology
Chemical Substances	Cytokines ; Inflammasomes ; NLR Family, Pyrin Domain-Containing 3 Protein ; NLRP3 protein, human
Language	English
Publishing date	2024-01-31
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2516098-9
ISSN	1999-4915 ; 1999-4915
ISSN (online)	1999-4915
ISSN	1999-4915
DOI	10.3390/v16020213
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