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  1. Article ; Online: The Use of R and R Packages in Biodiversity Conservation Research

    Jiangshan Lai / Dongfang Cui / Weijie Zhu / Lingfeng Mao

    Diversity, Vol 15, Iss 12, p

    2023  Volume 1202

    Abstract: R is one of the most powerful programming languages for conducting data analysis, modeling, and visualization. Although it is widely utilized in biodiversity conservation research, the comprehensive trends in R and R package usage and patterns in the ... ...

    Abstract R is one of the most powerful programming languages for conducting data analysis, modeling, and visualization. Although it is widely utilized in biodiversity conservation research, the comprehensive trends in R and R package usage and patterns in the field still remain unexplored. We conducted a comprehensive analysis of R and R package usage frequencies spanning fifteen years, from 2008 to 2022, encompassing over 24,100 research articles published in eight top biodiversity conservation journals. Within this extensive dataset, 10,220 articles (42.3% of the total) explicitly utilized R for data analysis. The use ratio of R demonstrated a consistent linear growth, escalating from 11.1% in 2008 to an impressive 70.6% in 2022. The ten top utilized R packages were vegan , lme4 , MuMIn , nlme , mgcv , raster , MASS , ggplot2 , car , and dismo . The frequency of R package utilization varied among journals, underscoring the distinct emphases each journal places on specific focuses of biodiversity conservation research. This analysis highlights the pivotal role of R, with its powerful statistical and data visualization capabilities, in empowering researchers to conduct in-depth analyses and gain comprehensive insights into various dimensions of biodiversity conservation science.
    Keywords biological conservation ; data analysis ; open-source ; popularity ; R language ; R packages ; Biology (General) ; QH301-705.5
    Subject code 333
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Using a 5G network in hospitals to reduce nosocomial infection during the COVID-19 pandemic

    Li Wen / Zhiwen Ou / Wenzhou Duan / Weijie Zhu / Xiongzhi Xiao / Ying Zhang / Huanquan Luo / Weibin Cheng / Wanmin Lian

    Communications Medicine, Vol 2, Iss 1, Pp 1-

    2022  Volume 4

    Abstract: Wen et al. discuss how implementing a 5G network in hospitals can be used to reduce nosocomial infections. Such systems can reduce the spread of COVID-19. ...

    Abstract Wen et al. discuss how implementing a 5G network in hospitals can be used to reduce nosocomial infections. Such systems can reduce the spread of COVID-19.
    Keywords Medicine ; R
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Ligustrazine alleviates pulmonary arterial hypertension in rats by promoting the formation of myocardin transcription complex in the nucleus of pulmonary artery smooth muscle cells

    Xichao Yu / Mingjie Wu / Qinhai Meng / Weijie Zhu / Chenyan Zhang / Bowen Liu / Yuewen Qi / Shuqun Gu / Xinyu Wang / Jingli Wen / Yu Li / Xu Qi

    Clinical and Translational Science, Vol 16, Iss 8, Pp 1369-

    2023  Volume 1380

    Abstract: Abstract Pulmonary arterial hypertension (PAH) is a pathophysiological state of abnormally elevated pulmonary arterial pressure caused by drugs, inflammation, toxins, viruses, hypoxia, and other risk factors. We studied the therapeutic effect and target ... ...

    Abstract Abstract Pulmonary arterial hypertension (PAH) is a pathophysiological state of abnormally elevated pulmonary arterial pressure caused by drugs, inflammation, toxins, viruses, hypoxia, and other risk factors. We studied the therapeutic effect and target of tetramethylpyrazine (tetramethylpyrazine [TMP]; ligustrazine) in the treatment of PAH and we speculated that dramatic changes in myocardin levels can significantly affect the progression of PAH. In vivo, the results showed that administration of TMP significantly prolonged the survival of PAH rats by reducing the proliferative lesions, right ventricular systolic pressure (RVSP), mean pulmonary arterial pressure (mPAP), and the Fulton index in the heart and lung of PAH rats. In vitro, TMP can regulate the levels of smooth muscle protein 22‐alpha (SM22‐α), and myocardin as well as intracellular cytokines such as NO, transforming growth factor beta (TGF‐β), and connective tissue growth factor (CTGF) in a dose‐dependent manner (25, 50, or 100 μM). Transfection of myocardin small interfering RNA (siRNA) aggravated the proliferation of pulmonary artery smooth muscle cells (PSMCs), and the regulatory effect of TMP on α‐smooth muscle actin (α‐SMA) and osteopontin (OPN) disappeared. The application of 10 nM estrogen receptor alpha (ERα) inhibitor MPP promoted the proliferation of PSMCs, but it does not affect the inhibition of TMP on PSMCs proliferation. Finally, we found that TMP promoted the nucleation of myocardin‐related transcription factor‐A (MRTF‐A) and combined it with myocardin. In conclusion, TMP can inhibit the transformation of PSMCs from the contractile phenotype to the proliferative phenotype by promoting the formation of the nuclear (MRTF‐A/myocardin) transcription complex to treat PAH.
    Keywords Therapeutics. Pharmacology ; RM1-950 ; Public aspects of medicine ; RA1-1270
    Subject code 610
    Language English
    Publishing date 2023-08-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Synthesis of micron-sized LiNi0.5Mn1.5O4 single crystals through in situ microemulsion/coprecipitation and characterization of their electrochemical capabilities

    Lu, Xiaojun / Cong Liu / Gang Yang / Weijie Zhu / Weili Li / Yang Yang / Zhongpei Lu

    Powder technology. 2019 Feb. 01, v. 343

    2019  

    Abstract: LiNi0.5Mn1.5O4 single crystals are synthesized using a two-step method consisting of emulsion/in situ co-precipitation and sintering reaction. In this process, Oil-in-water (Span80-Tween80-kerosene-H2O) emulsion is used as the in situ co-precipitation ... ...

    Abstract LiNi0.5Mn1.5O4 single crystals are synthesized using a two-step method consisting of emulsion/in situ co-precipitation and sintering reaction. In this process, Oil-in-water (Span80-Tween80-kerosene-H2O) emulsion is used as the in situ co-precipitation site. The co-precipitation is occurred within each emulsion droplet to produce the precursor when the aqueous precipitant is dropped into the emulsion. For the starting concentration of the nickel and manganese solution determines the composition of each emulsion droplet, micrometer-sized single crystals of LiNi0.5Mn1.5O4 are finally produced based on the size and concentration of the emulsion droplet. Bigger crystals are helpful on the cyclic performance, whereas smaller crystals are effective on the specific capacity but negative on the cyclic performance. LNM-0.5 μm sized crystals deliver specific capacity of 136 mA g−1 at the 1st cycle and retain 129 mAh g−1 after 200 cycles, maintaining 95% of its initial capacity. However, LNM-0.25 nanoparticles deliver capacity of 119 mAh g−1 after 200 cycles and only maintain 89% of its initial capacity. At 20C rate, LNM-0.5 sample retains specific capacity of 111 mAh g−1 after 200 cycles, which is higher than that of LNM-0.25 sample with retention of only 90 mAh g−1. Based on the characterization and electrochemical measurement, it is observed that the LNM-0.5 sample with preferential crystal size presents excellent cyclic performance and rate performance.
    Keywords coprecipitation ; crystals ; droplets ; electrochemistry ; emulsions ; manganese ; nanoparticles ; nickel ; powders
    Language English
    Dates of publication 2019-0201
    Size p. 445-453.
    Publishing place Elsevier B.V.
    Document type Article
    ISSN 0032-5910
    DOI 10.1016/j.powtec.2018.11.038
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Onlay Repair Technique for the Management of Ureteral Strictures

    Shengwei Xiong / Jie Wang / Weijie Zhu / Kunlin Yang / Guangpu Ding / Xuesong Li / Daniel D. Eun

    BioMed Research International, Vol

    A Comprehensive Review

    2020  Volume 2020

    Abstract: Ureteroplasty using onlay grafts or flaps emerged as an innovative procedure for the management of proximal and midureteral strictures. Autologous grafts or flaps used commonly in ureteroplasty include the oral mucosae, bladder mucosae, ileal mucosae, ... ...

    Abstract Ureteroplasty using onlay grafts or flaps emerged as an innovative procedure for the management of proximal and midureteral strictures. Autologous grafts or flaps used commonly in ureteroplasty include the oral mucosae, bladder mucosae, ileal mucosae, and appendiceal mucosae. Oral mucosa grafts, especially buccal mucosa grafts (BMGs), have gained wide acceptance as a graft choice for ureteroplasty. The reported length of BMG ureteroplasty ranged from 1.5 to 11 cm with success rates of 71.4%-100%. However, several studies have demonstrated that ureteroplasty using lingual mucosa grafts yields better recipient site outcomes and fewer donor site complications than that using BMGs. In addition, there is no essential difference in the efficacy and complication rates of BMG ureteroplasty using an anterior approach or a posterior approach. Intestinal graft or flap ureteroplasty was also reported. And the reported length of ileal or appendiceal flap ureteroplasty ranged from 1 to 8 cm with success rates of 75%-100%. Moreover, the bladder mucosa, renal pelvis wall, and penile/preputial skin have also been reported to be used for ureteroplasty and have achieved satisfactory outcomes, but each graft or flap has unique advantages and potential problems. Tissue engineering-based ureteroplasty through the implantation of patched scaffolds, such as the small intestine submucosa, with or without cell seeding, has induced successful ureteral regeneration structurally close to that of the native ureter and has resulted in good functional outcomes in animal models.
    Keywords Medicine ; R
    Subject code 333
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Dairy goat detection based on Faster R-CNN from surveillance video

    Wang, Dong / Dongjian He / Huan Li / Jing Xin / JingLei Tang / Weijie Zhu

    Computers and electronics in agriculture. 2018 Nov., v. 154

    2018  

    Abstract: As one of the most famous algorithms, Faster R-CNN has been applied to many fields. However, it is unlikely to be used to surveillance videos directly because of its low efficiency and precision. To deal with these problems, this paper puts forward an ... ...

    Abstract As one of the most famous algorithms, Faster R-CNN has been applied to many fields. However, it is unlikely to be used to surveillance videos directly because of its low efficiency and precision. To deal with these problems, this paper puts forward an object detection method which is based on Faster CNN to detect dairy goats in the surveillance video. It includes key frames extraction, foreground segmentation, region proposal and Fast R-CNN. The experimental results show that our method is more than twice as fast as Faster R-CNN and obtains 92.49% average precision. Our results suggest that our key frame extraction and region proposal method are helpful for detecting dairy goats.
    Keywords algorithms ; dairy goats ; monitoring
    Language English
    Dates of publication 2018-11
    Size p. 443-449.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 395514-x
    ISSN 0168-1699
    ISSN 0168-1699
    DOI 10.1016/j.compag.2018.09.030
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Single‐Cell RNA‐seq Reveals a Developmental Hierarchy Super‐Imposed Over Subclonal Evolution in the Cellular Ecosystem of Prostate Cancer

    Guangzhe Ge / Yang Han / Jianye Zhang / Xinxin Li / Xiaodan Liu / Yanqing Gong / Zhentao Lei / Jie Wang / Weijie Zhu / Yangyang Xu / Yiji Peng / Jianhua Deng / Bao Zhang / Xuesong Li / Liqun Zhou / Huiying He / Weimin Ci

    Advanced Science, Vol 9, Iss 15, Pp n/a-n/a (2022)

    2022  

    Abstract: Abstract Prostate cancer (PCa) is a complex disease. An ongoing accumulation of mutations results in increased genetic diversity, with the tumor acquiring distinct subclones. However, non‐genetic intra‐tumoral heterogeneity, the cellular differentiation ... ...

    Abstract Abstract Prostate cancer (PCa) is a complex disease. An ongoing accumulation of mutations results in increased genetic diversity, with the tumor acquiring distinct subclones. However, non‐genetic intra‐tumoral heterogeneity, the cellular differentiation state and the interplay between subclonal evolution and transcriptional heterogeneity are poorly understood. Here, the authors perform single‐cell RNA sequencing from 14 untreated PCa patients. They create an extensive cell atlas of the PCa patients and mapped developmental states onto tumor subclonal evolution. They identify distinct subclones across PCa patients and then stratify tumor cells into four transcriptional subtypes, EMT‐like (subtype 0), luminal A‐like (subtype 1), luminal B/C‐like (subtype 2), and basal‐like (subtype 3). These subtypes are hierarchically organized into stem cell‐like and differentiated status. Strikingly, multiple subclones within a single primary tumor present with distinct combinations of preferential subtypes. In addition, subclones show different communication strengths with other cell types within the tumor ecosystem, which may modulate the distinct transcriptional subtypes of the subclones. Notably, by integrating TCGA data, they discover that both tumor cell transcriptional heterogeneity and cellular ecosystem diversity correlate with features of a poor prognosis. Collectively, their study provides the analysis of subclonal and transcriptional heterogeneity and its implication for patient prognosis.
    Keywords cellular ecosystem ; epithelial‐to‐mesenchymal transition ; prostate cancer ; subtype ; transcriptional heterogeneity ; tumor subclone ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Experimental investigation on thermal OS/ORC (Oil Storage/Organic Rankine Cycle) system for waste heat recovery from diesel engine

    Shu, Gequn / Haiqiao Wei / Hua Tian / Mingru Zhao / Weijie Zhu / Xingyu Liang / Yongzhan Huo

    Energy. 2016 July 15, v. 107

    2016  

    Abstract: With urging needs to decrease the fuel consumption and environment pollution, energy saving and emission reduction technologies in the ICE (internal combustion engine) industry are developed. A thermal OS/ORC (Oil Storage/Organic Rankine Cycle) system ... ...

    Abstract With urging needs to decrease the fuel consumption and environment pollution, energy saving and emission reduction technologies in the ICE (internal combustion engine) industry are developed. A thermal OS/ORC (Oil Storage/Organic Rankine Cycle) system was constructed and preliminarily tested for WHR (Waste Heat Recovery) from exhaust gas of a 240 kW diesel engine. The heat balance test of diesel engine without OS/ORC was conducted first to investigate the varying property of exhaust gas, then the OS/ORC system was tested to show its ability against high temperature and variation of exhaust gas. The results show that thermal oil effectively dropped the working temperature of organic fluid to less than 210 °C, which is much lower than the decomposition temperature of many organic fluids. Also, thermal oil brought a significant inertia to the response of system which could be positive against the variation of engine condition. In order to learn more about the operating characteristics of OS/ORC system, the impact of important parameters on each other was investigated quantitatively as well as on the performance of OS/ORC system. The results show that within the given range, higher evaporating pressure can obviously improve the performance of OS/ORC while the impact of superheat is nearly negligible.
    Keywords diesel engines ; energy conservation ; energy use and consumption ; evaporation ; heat recovery ; industry ; oils ; pollution ; temperature ; wastes
    Language English
    Dates of publication 2016-0715
    Size p. 693-706.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 2019804-8
    ISSN 0360-5442 ; 0360-5442
    ISSN (online) 0360-5442
    ISSN 0360-5442
    DOI 10.1016/j.energy.2016.04.062
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: Experimental comparison of R123 and R245fa as working fluids for waste heat recovery from heavy-duty diesel engine

    Shu, Gequn / Hua Tian / Mingru Zhao / Weijie Zhu / Yongzhan Huo

    Energy. 2016 Nov. 15, v. 115

    2016  

    Abstract: Organic Rankine Cycle (ORC) on-board is a solution for vehicles to save energy and reduce emission. Considering the characteristics of waste heat from vehicle, the criterions of the suitable working fluid are very strict. R123 and R245fa have been widely ...

    Abstract Organic Rankine Cycle (ORC) on-board is a solution for vehicles to save energy and reduce emission. Considering the characteristics of waste heat from vehicle, the criterions of the suitable working fluid are very strict. R123 and R245fa have been widely used in companies and labs, however, the difference of their properties under different engine conditions still requires further study. During this research, a series of experiments have been done to compare the performance of these two working fluids, what's more, to determine under which engine conditions they are suitable separately. These experimental comparisons are new and important for the targeting design of ORC for vehicles. The result shows that, considering the difference of thermodynamic properties and the limited cooling capacity on board, R123 shows its advantage for the waste heat recovery at heavy duty, while R245fa is more suitable at light-and-medium duty. These properties make R123 suitable for the ORC designed for long-haul heavy-duty truck, while R245fa is suggested for city bus. The following performance test of R123 for waste heat recovery from heavy-duty diesel engine shows that the maximum fuel consumption improvement can be as much as 2.8%.
    Keywords business enterprises ; diesel engines ; energy use and consumption ; heat recovery ; wastes
    Language English
    Dates of publication 2016-1115
    Size p. 756-769.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 2019804-8
    ISSN 0360-5442 ; 0360-5442
    ISSN (online) 0360-5442
    ISSN 0360-5442
    DOI 10.1016/j.energy.2016.09.082
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Experimental investigations on a cascaded steam-/organic-Rankine-cycle (RC/ORC) system for waste heat recovery (WHR) from diesel engine

    Yu, Guopeng / Gequn Shu / Hua Tian / Weijie Zhu / Yongzhan Huo

    Energy conversion and management. 2016 Dec. 01, v. 129

    2016  

    Abstract: A novel cascaded RC/ORC system that comprises a steam Rankine cycle as the high-temperature loop (H-RC) and an organic Rankine cycle as the low-temperature loop (L-ORC) was constructed and experimentally investigated to recover waste heat from exhaust ... ...

    Abstract A novel cascaded RC/ORC system that comprises a steam Rankine cycle as the high-temperature loop (H-RC) and an organic Rankine cycle as the low-temperature loop (L-ORC) was constructed and experimentally investigated to recover waste heat from exhaust gas of a heavy-duty diesel engine (DE). By monitoring key parameters of the RC/ORC system against time, good system stability and satisfying thermal states of working fluids were observed. Impacts that the engine operations have on this proposed waste-heat-recovery (WHR) system were studied, indicating that waste heat recovered from the gas increases gradually and greatly as the engine load increases, yet decreases slightly as the speed grows. At full loads at speeds lower than 2050rpm, up to 101.5kW of waste heat can be abstracted from the gas source, showing a promising heat transfer potential. Besides, observations of key exergy states as well as estimations and comparisons of potential output power were carried out stepwise. Results indicated that up to 12.7kW of output power could be obtained by the novel RC/ORC system under practical estimations. Comparing to the basic diesel engine, the power increment reaches up to 5.6% by equipping the cascaded RC/ORC system.
    Keywords diesel engines ; exergy ; heat recovery ; monitoring ; steam ; wastes
    Language English
    Dates of publication 2016-1201
    Size p. 43-51.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 2000891-0
    ISSN 0196-8904
    ISSN 0196-8904
    DOI 10.1016/j.enconman.2016.10.010
    Database NAL-Catalogue (AGRICOLA)

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