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  1. Article: Ist eine Impfpflicht gegen das Coronavirus nötig?

    Wein, Thomas

    Wirtschaftsdienst (Hamburg, Germany : 1949)

    2021  Volume 101, Issue 2, Page(s) 114–120

    Abstract: The end of the pandemic requires that SARS-CoV-2 vaccines be used. However, vaccination itself can lead to temporary adverse health effects and/or long-term damage. Vaccination initially represents a private good demanded by an individual cost-benefit ... ...

    Title translation Is Mandatory Vaccination Against the Coronavirus Necessary?
    Abstract The end of the pandemic requires that SARS-CoV-2 vaccines be used. However, vaccination itself can lead to temporary adverse health effects and/or long-term damage. Vaccination initially represents a private good demanded by an individual cost-benefit calculus; however, it also creates positive externalities and thus too few individual incentives to vaccinate. Getting vaccinated is not a dominant rational strategy, neither in the overall population, nor among the old and the young, nor when the long-term costs of the pandemic are taken into account. It is all the more important to "price in" the long-term consequences of a lasting pandemic.
    Language German
    Publishing date 2021-02-20
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 202814-1
    ISSN 1613-978X ; 0043-6275
    ISSN (online) 1613-978X
    ISSN 0043-6275
    DOI 10.1007/s10273-021-2852-2
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  2. Book ; Thesis: Rolle von reaktiven Sauerstoffspezies für die hepatozelluläre Genexpression der Hämoxygenase-1 nach hämorrhagischem Schock

    Wein, Thomas

    2004  

    Author's details vorgelegt von: Thomas Wein
    Language German
    Size 88 Bl. : Ill., graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Saarbrücken, Univ., Diss., 2004
    HBZ-ID HT014633009
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2003 MB 1605 order for loan Magazin

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  3. Article ; Online: Niedrigzinsen bei Bausparkassen

    Wein, Thomas

    Wirtschaftsdienst Vol. 97, No. 4 , p. 294-298

    ein Urteil des Bundesgerichtshofs = Low interest rates and building societies ; a judgment of the federal high court of justice

    2017  Volume 97, Issue 4, Page(s) 294–298

    Abstract: At the end of February 2017 the Federal High Court of Justice rules that building societies are allowed to terminate old contracts ahead of schedule. A lot of old contracts are problematic in the viewpoint of building societies due to high deposit ... ...

    Author's details Thomas Wein
    Abstract At the end of February 2017 the Federal High Court of Justice rules that building societies are allowed to terminate old contracts ahead of schedule. A lot of old contracts are problematic in the viewpoint of building societies due to high deposit interest rates. High deposit interest rates are dangerous for building societies in times of low interest rates, especially if low interest rates are longlasting. The Federal High Court of Justice follows the opinion of the building societies that during saving periods, building societies can be seen as borrowers, and borrowers have the (exceptional) right to terminate contracts after ten years, which is established in the German Civil Law. A microeconomic intertemporal consumption model calculates this as an overreaction byf the Court: Building societies should only be allowed to reduce deposit interest rate to be compensated for non existing loan contracts.

    Ende Februar 2017 hat der Bundesgerichtshof Bausparkassen, die Bausparern mit vertraglich zugesicherten hohen Einlagenzinsen aus Altverträgen vorfristig gekündigt haben, Recht gegeben. Der Autor stellt die Funktionsweise des Bausparens dar. In der aktuellen Niedrigzinsphase könnte es dazu kommen, dass der Darlehenszinssatz geringer als der Sparzinssatz ist. Dann würde das Geschäftsmodell der Bausparkassen kollabieren. Ein mikroökonomisches Modell zeigt beispielhaft, in welcher Höhe den Bausparkassen Schaden aus der Zinskonstellation entstehen können. Die betroffenen Kunden sollten von den Sparkassen in Höhe der entgangenen Nettoerträge entschädigt werden. Dies hält der Autor für eine bessere Lösung als die erlaubte vorfristige Kündigung.
    Language German
    Size Online-Ressource
    Publisher Springer
    Publishing place Heidelberg
    Document type Article ; Online
    Note Zusammenfassung in englischer Sprache
    ZDB-ID 2079503-8 ; 202814-1
    ISSN 1613-978X ; 0043-6275
    ISSN (online) 1613-978X
    ISSN 0043-6275
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  4. Book ; Article ; Online: Privacy paradox - Economic uncertainty theory and legal consequences

    Geschonke, Sarah / Wein, Thomas

    2020  

    Abstract: Internet users generously disclose personal information to consume supposedly "free" digital services despite severe privacy concerns-a phenomenon termed privacy paradox. Humanities have thoroughly studied this discrepancy in attitude and behavior, yet ... ...

    Abstract Internet users generously disclose personal information to consume supposedly "free" digital services despite severe privacy concerns-a phenomenon termed privacy paradox. Humanities have thoroughly studied this discrepancy in attitude and behavior, yet have not developed a conclusive explanation for its occurrence, let alone a means to counter it. Both the quantity and the quality of data privacy laws, as well as the increasing number of court rulings dealing with digital business models, show the urgent need to better understand the cause of the privacy paradox and to mitigate it. This paper analyzes the contradictory phenomenon from an economic point of view. By applying the two-state of the world-model, the authors demonstrate that uncertainty about the extent and the likelihood of a data breach are explanatory factors for the privacy paradox. Taking the European General Data Protection Regulation as an exemplary showcase, the authors further examine the role of privacy laws to offset Internet users' inconsistent privacy behavior. In theory, such a "rights and remedies" scheme is intended to counter the uncertainty factors provoking the privacy paradox; however, in practice, this intention is only partially served.
    Keywords ddc:330 ; K24 ; L15 ; L86 ; data protection ; Privacy paradox ; Legal remedies
    Subject code 303
    Language English
    Publisher Lüneburg: Leuphana Universität Lüneburg, Institut für Volkswirtschaftslehre
    Publishing country de
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Book ; Thesis: Sympathische Regulation, Herzfrequenzverhalten und Leistungsfähigkeit frequenzadaptierter Schrittmacherpatienten im Vergleich zu Herzgesunden

    Wein, Thomas Karl Louis

    1996  

    Author's details vorgelegt von Thomas Karl Lous Wein
    Language German
    Size 50 S. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Tübingen, Univ., Diss., 1996
    HBZ-ID HT007421876
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    97 D 362 order for loan Magazin

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  6. Book ; Online: Preventing margin squeeze

    Wein, Thomas

    an unsolvable puzzle for competition policy? ; the case of the German gasoline market

    (University of Lüneburg Working Paper Series in Economics ; 309)

    2014  

    Abstract: There is a discrepancy between Europe and the United States on whether margin squeeze is a relevant question for competition law and policy. Beyond this question, it is unclear whether law and the Cartel Office can detect margin squeeze, assuming it is ... ...

    Author's details Thomas Wein
    Series title University of Lüneburg Working Paper Series in Economics ; 309
    Abstract There is a discrepancy between Europe and the United States on whether margin squeeze is a relevant question for competition law and policy. Beyond this question, it is unclear whether law and the Cartel Office can detect margin squeeze, assuming it is necessary to look into the matter. In Germany, politicians have decided the given rule against margin squeeze should not be abolished, especially because of problems in the gasoline market. This paper discusses a comprehensive microeconomic new explanation on margin squeeze, and discusses some of the problems used to detect margin squeeze in the gasoline market. After comparing theoretical shortcuts, practical challenges and efforts towards enforcement with expected benefits, this paper concludes competition law should ignore the margin squeeze problem.
    Keywords margin squeeze ; gasoline market ; market dominance
    Language English
    Size Online-Ressource (23 S.), graph. Darst.
    Publisher Univ., Inst. für Volkswirtschaftslehre
    Publishing place Lüneburg
    Document type Book ; Online
    Database ECONomics Information System

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  7. Book ; Online: Verdrängungspreise an Tankstellen?

    Kleineberg, Christoph / Wein, Thomas

    (University of Lüneburg working paper series in economics ; no. 375)

    2017  

    Author's details von Christoph Kleineberg und Thomas Wein
    Series title University of Lüneburg working paper series in economics ; no. 375
    Language German
    Size 1 Online-Ressource (circa 29 Seiten)
    Document type Book ; Online
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  8. Book ; Online: Collusive upward gasoline price movements in medium-sized German cities

    Neukirch, Arne / Wein, Thomas

    (University of Lüneburg working paper series in economics ; no. 363)

    2016  

    Abstract: Do we have effective competition between the gasoline's big five oligopolists (Aral, Shell, Esso, Total and Jet) and fringe gasoline stations? Using 2014 Market Transparency price data from 66 cities with populations between 60,000 and 100,000, we ... ...

    Author's details by Arne Neukirch and Thomas Wein
    Series title University of Lüneburg working paper series in economics ; no. 363
    Abstract Do we have effective competition between the gasoline's big five oligopolists (Aral, Shell, Esso, Total and Jet) and fringe gasoline stations? Using 2014 Market Transparency price data from 66 cities with populations between 60,000 and 100,000, we analyze which brands lead price increases, the first average price mark-up in the evening, and the trend on price increases until midnight. Furthermore, we measure the response time it takes for competitors to react to these price increases, and how much prices change from the beginning to the end of a day. By watching local activities of the big brands, it is possible to measure how smaller businesses, such as Jet or independent retailers, react to Aral's and Shell's price changes. Multivariate estimations allows to control for gasoline type (regular or diesel), school holidays, weekends, weekdays, location -such as East or West Germany-, wholesale and starting prices. Descriptive results show the typical patterns. Aral (or Shell) will start a price increase round, and then Shell (or Aral) will more or less immediately follow. Total, Esso and Non-Oligopolists react within one or two hours. Jet behaves more as an "outsider" with later reaction times and lower price mark-ups. Multivariate estimation indicates that the single cause "price change by competitors" is less important and nearly irrelevant for Jet.
    Keywords Market power ; collusive behavior ; gasoline market
    Language English
    Size 1 Online-Ressource (circa 36 Seiten), Illustrationen
    Publisher Leuphana Universität Lüneburg, Institut für Volkswirtschaftslehre
    Publishing place Lüneburg
    Document type Book ; Online
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  9. Article: Das Auf und Ab der Tankstellenpreise

    Neukirch, Arne / Wein, Thomas

    List-Forum für Wirtschafts- und Finanzpolitik Vol. 42, No. 2 , p. 195-245

    die Rolle des Binnen- und Außenwettbewerbs

    2016  Volume 42, Issue 2, Page(s) 195–245

    Author's details Arne Neukirch, Thomas Wein
    Keywords Marktbeherrschung ; Parallelverhalten ; Benzinpreise
    Language German
    Publisher Springer Gabler
    Publishing place Wiesbaden
    Document type Article
    Note Zusammenfassung in englischer Sprache
    ZDB-ID 1005430-3
    ISSN 0342-2623
    Database ECONomics Information System

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  10. Article ; Online: Fragment-based discovery of orphan nuclear receptor Nur77/NGFI-B ligands.

    Arifi, Silvia / Zaienne, Daniel / Heering, Jan / Wein, Thomas / Zhubi, Rezart / Chaikuad, Apirat / Knapp, Stefan / Marschner, Julian A / Merk, Daniel

    Bioorganic chemistry

    2022  Volume 129, Page(s) 106164

    Abstract: The transcription factor nerve growth factor-induced clone B (NGFI-B, Nur77, NR4A1) is an orphan nuclear receptor playing a role in cell survival and apoptosis regulation. Pharmacological Nur77 modulation holds promise for cancer and (neuro-)inflammatory ...

    Abstract The transcription factor nerve growth factor-induced clone B (NGFI-B, Nur77, NR4A1) is an orphan nuclear receptor playing a role in cell survival and apoptosis regulation. Pharmacological Nur77 modulation holds promise for cancer and (neuro-)inflammatory disease treatment. The available Nur77 ligand scaffolds based on highly lipophilic natural products cytosporone B, celastrol and isoalantolactone are inadequate for the development of potent Nur77 modulators with favorable properties as chemical tools and future drugs. By fragment library screening and subsequent modeling for fragment extension, we have obtained a set of new Nur77 ligands offering alternative chemotypes for the development of Nur77 agonists and inverse agonists. Computer-aided fragment extension in a second stage screening yielded a Nur77 agonist with significant activation efficacy and preference over the related NR4A receptors.
    MeSH term(s) Humans ; Ligands ; Orphan Nuclear Receptors/therapeutic use ; Receptors, Steroid ; Nuclear Receptor Subfamily 4, Group A, Member 1 ; Apoptosis ; Neoplasms/drug therapy
    Chemical Substances Ligands ; Orphan Nuclear Receptors ; Receptors, Steroid ; Nuclear Receptor Subfamily 4, Group A, Member 1
    Language English
    Publishing date 2022-09-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 120080-x
    ISSN 1090-2120 ; 0045-2068
    ISSN (online) 1090-2120
    ISSN 0045-2068
    DOI 10.1016/j.bioorg.2022.106164
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