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  1. Article ; Online: Quantum Nondemolition Measurement of a Quantum Squeezed State Beyond the 3 dB Limit.

    Lei, C U / Weinstein, A J / Suh, J / Wollman, E E / Kronwald, A / Marquardt, F / Clerk, A A / Schwab, K C

    Physical review letters

    2016  Volume 117, Issue 10, Page(s) 100801

    Abstract: We use a reservoir engineering technique based on two-tone driving to generate and stabilize a quantum squeezed state of a micron-scale mechanical oscillator in a microwave optomechanical system. Using an independent backaction-evading measurement to ... ...

    Abstract We use a reservoir engineering technique based on two-tone driving to generate and stabilize a quantum squeezed state of a micron-scale mechanical oscillator in a microwave optomechanical system. Using an independent backaction-evading measurement to directly quantify the squeezing, we observe 4.7±0.9  dB of squeezing below the zero-point level surpassing the 3 dB limit of standard parametric squeezing techniques. Our measurements also reveal evidence for an additional mechanical parametric effect. The interplay between this effect and the optomechanical interaction enhances the amount of squeezing obtained in the experiment.
    Language English
    Publishing date 2016-09-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.117.100801
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: QUANTUM MECHANICS. Quantum squeezing of motion in a mechanical resonator.

    Wollman, E E / Lei, C U / Weinstein, A J / Suh, J / Kronwald, A / Marquardt, F / Clerk, A A / Schwab, K C

    Science (New York, N.Y.)

    2015  Volume 349, Issue 6251, Page(s) 952–955

    Abstract: According to quantum mechanics, a harmonic oscillator can never be completely at rest. Even in the ground state, its position will always have fluctuations, called the zero-point motion. Although the zero-point fluctuations are unavoidable, they can be ... ...

    Abstract According to quantum mechanics, a harmonic oscillator can never be completely at rest. Even in the ground state, its position will always have fluctuations, called the zero-point motion. Although the zero-point fluctuations are unavoidable, they can be manipulated. Using microwave frequency radiation pressure, we have manipulated the thermal fluctuations of a micrometer-scale mechanical resonator to produce a stationary quadrature-squeezed state with a minimum variance of 0.80 times that of the ground state. We also performed phase-sensitive, back-action evading measurements of a thermal state squeezed to 1.09 times the zero-point level. Our results are relevant to the quantum engineering of states of matter at large length scales, the study of decoherence of large quantum systems, and for the realization of ultrasensitive sensing of force and motion.
    Language English
    Publishing date 2015-08-28
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.aac5138
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Thermally induced parametric instability in a back-action evading measurement of a micromechanical quadrature near the zero-point level.

    Suh, J / Shaw, M D / Leduc, H G / Weinstein, A J / Schwab, K C

    Nano letters

    2012  Volume 12, Issue 12, Page(s) 6260–6265

    Abstract: We report the results of back-action evading experiments utilizing a tightly coupled electro-mechanical system formed by a radio frequency micromechanical resonator parametrically coupled to a NbTiN superconducting microwave resonator. Due to excess ... ...

    Abstract We report the results of back-action evading experiments utilizing a tightly coupled electro-mechanical system formed by a radio frequency micromechanical resonator parametrically coupled to a NbTiN superconducting microwave resonator. Due to excess dissipation in the microwave resonator, we observe a parametric instability induced by a thermal shift of the mechanical resonance frequency. In light of these measurements, we discuss the constraints on microwave dissipation needed to perform BAE measurements far below the zero-point level.
    Language English
    Publishing date 2012-11-15
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/nl303353r
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Quantum mechanics. Mechanically detecting and avoiding the quantum fluctuations of a microwave field.

    Suh, J / Weinstein, A J / Lei, C U / Wollman, E E / Steinke, S K / Meystre, P / Clerk, A A / Schwab, K C

    Science (New York, N.Y.)

    2014  Volume 344, Issue 6189, Page(s) 1262–1265

    Abstract: Quantum fluctuations of the light field used for continuous position detection produce stochastic back-action forces and ultimately limit the sensitivity. To overcome this limit, the back-action forces can be avoided by giving up complete knowledge of ... ...

    Abstract Quantum fluctuations of the light field used for continuous position detection produce stochastic back-action forces and ultimately limit the sensitivity. To overcome this limit, the back-action forces can be avoided by giving up complete knowledge of the motion, and these types of measurements are called "back-action evading" or "quantum nondemolition" detection. We present continuous two-tone back-action evading measurements with a superconducting electromechanical device, realizing three long-standing goals: detection of back-action forces due to the quantum noise of a microwave field, reduction of this quantum back-action noise by 8.5 ± 0.4 decibels (dB), and measurement imprecision of a single quadrature of motion 2.4 ± 0.7 dB below the mechanical zero-point fluctuations. Measurements of this type will find utility in ultrasensitive measurements of weak forces and nonclassical states of motion.
    Language English
    Publishing date 2014-06-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.1253258
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  5. Article: Atemwegsinfektionen durch Haemophilus influenzae bei Erwachsenen.

    Weinstein, A J

    Infection

    1987  Volume 15 Suppl 3, Page(s) S109–12

    Abstract: Pneumonia counts as one of the most frequent severe Haemophilus influenzae infections to afflict adults. 60% of patients with pneumonia caused by type b H. influenzae are more than 50 years old, 30% to 40% are alcoholics, and 30% to 40% have chronic ... ...

    Title translation Respiratory tract infections caused by Haemophilus influenzae in adults.
    Abstract Pneumonia counts as one of the most frequent severe Haemophilus influenzae infections to afflict adults. 60% of patients with pneumonia caused by type b H. influenzae are more than 50 years old, 30% to 40% are alcoholics, and 30% to 40% have chronic pulmonary disease or other concurrent illness. In the majority of cases there is multilobular, maculate, diffuse and usually bilateral involvement of the pulmonary tissue. The mortality rate due to type b H. influenzae pneumonia ranges between 30% and 40%. In patients with non-bacteriaemic pneumonia caused by non-encapsulated strains of H. influenzae it is rare for several lobes to be involved, there is little exudation and the mortality rate is low. H. influenzae is a significant pathogen in acute epiglottitis in adults and it also appears to play an important role in acute exacerbations of chronic obstructive lung disease (COLD) and acute sinusitis. beta-lactamase production mediated by R-factors or plasmids of gram-negative bacteria is responsible for ampicillin resistance. In 1978 the overall rate of resistance of H. influenzae to ampicillin in American hospitals amounted to 18%. H. influenzae are found in the nasopharynx of people exposed to others infected with H. influenzae. The risk of secondary infection in children who come into contact with patients infected with type b H. influenzae amounts to approximately 2.1%. Adults in close contact with children suffering from severe H. influenzae infections must be warned of the possible risks of secondary infection.
    MeSH term(s) Adult ; Drug Resistance, Microbial ; Epiglottitis/microbiology ; Haemophilus Infections/microbiology ; Haemophilus Infections/transmission ; Haemophilus influenzae/isolation & purification ; Humans ; Lung Diseases, Obstructive/microbiology ; Pneumonia/microbiology ; Respiratory Tract Infections/microbiology ; Respiratory Tract Infections/transmission ; Sinusitis/microbiology
    Language German
    Publishing date 1987
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 185104-4
    ISSN 1439-0973 ; 0300-8126 ; 0173-2129
    ISSN (online) 1439-0973
    ISSN 0300-8126 ; 0173-2129
    DOI 10.1007/bf01650652
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  6. Article: Sexually transmittable diseases and other genital infections during adolescence.

    Weinstein, A J

    The Journal of reproductive medicine

    1984  Volume 29, Issue 6, Page(s) 411–415

    MeSH term(s) Adolescent ; Candidiasis, Vulvovaginal/diagnosis ; Female ; Genital Diseases, Female/diagnosis ; Genital Diseases, Male/diagnosis ; Gonorrhea/diagnosis ; Herpes Genitalis/diagnosis ; Humans ; Male ; Pelvic Inflammatory Disease/diagnosis ; Sexually Transmitted Diseases/diagnosis ; Syphilis/diagnosis ; Trichomonas Vaginitis/diagnosis ; Urethritis/diagnosis ; Vaginitis/diagnosis
    Language English
    Publishing date 1984-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390916-5
    ISSN 1943-3565 ; 0024-7758
    ISSN (online) 1943-3565
    ISSN 0024-7758
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  7. Article: Cephalexin in the therapy of infections of the urinary tract.

    Weinstein, A J

    Postgraduate medical journal

    1983  Volume 59 Suppl 5, Page(s) 40–42

    Abstract: Cephalexin is an oral cephalosporin which is widely used in the treatment of urinary tract infections. It is readily absorbed from the gastrointestinal tract and achieves high concentrations in the urine, where it retains its full activity against the ... ...

    Abstract Cephalexin is an oral cephalosporin which is widely used in the treatment of urinary tract infections. It is readily absorbed from the gastrointestinal tract and achieves high concentrations in the urine, where it retains its full activity against the organisms commonly responsible for urinary tract infections. It also achieves adequate serum levels. Cephalexin is essentially nontoxic at recommended doses, and its clinical efficacy in urinary tract infections has been repeatedly documented in numerous studies since 1971.
    MeSH term(s) Acute Disease ; Adult ; Bacteriuria/diagnosis ; Cephalexin/therapeutic use ; Cephalexin/urine ; Chronic Disease ; Cystitis/drug therapy ; Female ; Humans ; Kinetics ; Male ; Prostatitis/drug therapy ; Recurrence ; Urinary Tract Infections/drug therapy
    Chemical Substances Cephalexin (OBN7UDS42Y)
    Language English
    Publishing date 1983
    Publishing country England
    Document type Journal Article
    ZDB-ID 80325-x
    ISSN 1469-0756 ; 0032-5473
    ISSN (online) 1469-0756
    ISSN 0032-5473
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  8. Article: Selection of antimicrobial therapy.

    Weinstein, A J

    Instructional course lectures

    1982  Volume 31, Page(s) 14–18

    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Cephalosporins/therapeutic use ; Child ; Enterobacteriaceae Infections/drug therapy ; Humans ; Osteomyelitis/drug therapy ; Osteomyelitis/etiology ; Penicillins/therapeutic use ; Pseudomonas Infections/drug therapy ; Staphylococcal Infections/drug therapy ; Streptococcal Infections/drug therapy ; Surgical Wound Infection/complications ; Vascular Diseases/complications
    Chemical Substances Anti-Bacterial Agents ; Cephalosporins ; Penicillins
    Language English
    Publishing date 1982
    Publishing country United States
    Document type Journal Article
    ZDB-ID 802490-x
    ISSN 0065-6895
    ISSN 0065-6895
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  9. Article: The new cephalosporins and penicillins.

    Weinstein, A J

    Comprehensive therapy

    1982  Volume 8, Issue 2, Page(s) 26–31

    MeSH term(s) Azlocillin ; Bacterial Infections/drug therapy ; Cefoperazone ; Cefotaxime/therapeutic use ; Cephalosporins/therapeutic use ; Cephamycins/therapeutic use ; Humans ; Mezlocillin ; Moxalactam ; Penicillins/therapeutic use ; Piperacillin
    Chemical Substances Cephalosporins ; Cephamycins ; Penicillins ; Cefoperazone (7U75I1278D) ; Azlocillin (HUM6H389W0) ; Cefotaxime (N2GI8B1GK7) ; Mezlocillin (OH2O403D1G) ; Moxalactam (VUF6C936Z3) ; Piperacillin (X00B0D5O0E)
    Language English
    Publishing date 1982-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 752013-x
    ISSN 1559-1190 ; 0098-8243
    ISSN (online) 1559-1190
    ISSN 0098-8243
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  10. Article: Osteomyelitis: microbiologic, clinical, and therapeutic considerations.

    Weinstein, A J

    Primary care

    1981  Volume 8, Issue 4, Page(s) 557–569

    Abstract: A distinction between "acute" osteomyelitis and "chronic" osteomyelitis is difficult on both clinical and histopathologic grounds. The classification of osteomyelitis into three groups (hematogenous osteomyelitis, osteomyelitis secondary to a contiguous ... ...

    Abstract A distinction between "acute" osteomyelitis and "chronic" osteomyelitis is difficult on both clinical and histopathologic grounds. The classification of osteomyelitis into three groups (hematogenous osteomyelitis, osteomyelitis secondary to a contiguous focus of infection, and osteomyelitis associated with vascular insufficiency) allows the physician to clearly distinguish among the types of infection on the bases of (1) the pathogenesis, (2) the bones involved, (3) the microorganisms responsible, and (4) the therapy. When antimicrobial agents are administered to a patient with any form of osteomyelitis, a bactericidal antibiotic should be employed, if possible. If feasible, a parenteral route of administration should be utilized, and therapy should be administered for a prolonged period of time. When more than one bactericidal antibiotic has been demonstrated to be effective against the isolated microorganisms, the least toxic agent should be selected.
    MeSH term(s) Adolescent ; Aged ; Anti-Bacterial Agents/therapeutic use ; Bacterial Infections/diagnosis ; Bacterial Infections/drug therapy ; Child ; Humans ; Middle Aged ; Osteomyelitis/complications ; Osteomyelitis/diagnosis ; Osteomyelitis/drug therapy ; Vascular Diseases/complications
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 1981-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604005-6
    ISSN 1558-299X ; 0095-4543
    ISSN (online) 1558-299X
    ISSN 0095-4543
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