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  1. Article ; Online: In Vivo, Ex Vivo and In Silico Methods to Study Pancreas Biology During Health and Disease.

    Weitz, Jonathan

    Journal of visualized experiments : JoVE

    2023  , Issue 193

    Abstract: Articles discussed: Delgadillo-Silva, L. F., Akhtar, M. N., Tasoz, E., Ninov, N. Simultaneous calcium imaging and glucose stimulation in living zebrafish to investigate in vivo beta-cell function. Journal of Visualized Experiments. (175), e62347 (2021). ...

    Abstract Articles discussed: Delgadillo-Silva, L. F., Akhtar, M. N., Tasoz, E., Ninov, N. Simultaneous calcium imaging and glucose stimulation in living zebrafish to investigate in vivo beta-cell function. Journal of Visualized Experiments. (175), e62347 (2021). Felix-Martinez, G. J.,Nicolas-Mata, A., Godinez-Fernandez, J. R. Computational reconstruction of pancreatic islets as a tool for structural and functional analysis. Journal of Visualized Experiments. (181), e63352 (2022). Huber, M. K. et al. Observing islet function and islet-immune cell interactions in live pancreatic tissue slices. Journal of Visualized Experiments. (170), e62207 (2021). Park, I.,Kim, P. Stabilized longitudinal in vivo cellular-level visualization of the pancreas in a murine model with a pancreatic intravital imaging window. Journal of Visualized Experiments. (171), e62538 (2021). Stozer, A. et al. Confocal laser scanning microscopy of calcium dynamics in acute mouse pancreatic tissue slices. Journal of Visualized Experiments. (170), e62293 (2021). Zhou, X. et al. Establishment of a mouse severe acute pancreatitis model using retrograde injection of sodium taurocholate into the biliopancreatic duct. Journal of Visualized Experiments. (182), e63129 (2022).
    MeSH term(s) Animals ; Mice ; Acute Disease ; Calcium ; Zebrafish ; Pancreatitis ; Pancreas/surgery ; Disease Models, Animal ; Biology
    Chemical Substances Calcium (SY7Q814VUP)
    Language English
    Publishing date 2023-03-17
    Publishing country United States
    Document type Video-Audio Media ; Editorial ; Research Support, N.I.H., Extramural
    ZDB-ID 2259946-0
    ISSN 1940-087X ; 1940-087X
    ISSN (online) 1940-087X
    ISSN 1940-087X
    DOI 10.3791/64938
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Thesis: Langzeitergebnisse nach Resektion eines Magenkarzinoms

    Klintz, Marlene / Fahlke, Jörg / Weitz, Jürgen

    Ein Vergleich zwischen Adenokarzinomen des gastroösophagealen Übergangs (Siewert Typ II und III) und Adenokarzinomen des mittleren und distalen Magendrittels hinsichtlich klinisch-pathologischer Merkmale und der Prognose

    2020  

    Title variant zwei, drei
    Institution Otto-von-Guericke-Universität Magdeburg
    Author's details vorgelegt von Marlene Klintz aus Berlin ; Gutachter: Jörg Fahlke ; Jürgen Weitz
    Keywords Magenkrebs ; Adenocarcinom
    Subject Carcinoma ventriculi ; Magencarcinom ; Magenkarzinom ; Adenokarzinom ; Carcinoma adenomatosum ; Drüsenkrebs
    Language German
    Size 9 ungezählte Blätter, 92, XVI Blätter, Diagramme, Formulare
    Publisher Otto-von-Guericke-Universität Magdeburg
    Publishing place Magdeburg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Magdeburg, 2021
    HBZ-ID HT021233619
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2022 E 170 order for loan Magazin

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  3. Article: Der onkologische Notfall: Hohlorganperforation bei einem Pankreaskarzinom

    Hempel, S. / Weitz, J.

    Krebs im Focus

    2023  Volume 17, Issue -, Page(s) 35

    Language German
    Document type Article
    ZDB-ID 2761631-9
    Database Current Contents Medicine

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  4. Article ; Online: Das familiäre Pankreaskarzinomsyndrom.

    Seifert, Lena / Weitz, Jürgen

    Chirurgie (Heidelberg, Germany)

    2023  Volume 94, Issue 5, Page(s) 406–411

    Abstract: In contrast to many other malignant entities the risk factors for pancreatic cancer are mostly unknown. Hereditary factors are causative in about 3-6% of all pancreatic cancers. In addition to hereditary tumor disposition syndromes and hereditary ... ...

    Title translation Familial pancreatic cancer syndrome.
    Abstract In contrast to many other malignant entities the risk factors for pancreatic cancer are mostly unknown. Hereditary factors are causative in about 3-6% of all pancreatic cancers. In addition to hereditary tumor disposition syndromes and hereditary pancreatitis, the familial pancreatic cancer syndrome accounts for about 75% of all hereditary pancreatic cancers. A familial pancreatic cancer syndrome is present when at least two first-degree relatives in a family have histologically proven pancreatic cancer and there are no criteria for another hereditary syndrome. An underlying uniform monogenetic gene defect in familial pancreatic cancer syndrome is currently unknown and a germline mutation in the BRCA2 gene is so far the most frequently identified genetic alteration. Patients at risk for familial pancreatic cancer should be offered participation in registry studies with associated early detection programs (e.g., the FaPaCa registry). These enable the detection of high-grade neoplasms and pancreatic cancer in the early stages, which appears to reduce mortality; however, the detected pancreatic lesions are often incorrectly diagnostically classified, and patients undergo complex pancreatic resection despite benign findings. Finally, studies have so far not been able to clearly clarify whether patients at risk benefit from an early detection program. According to current data, prophylactic operations are not indicated for familial pancreatic cancer syndrome and should only be performed if there is evidence of a suspicious finding that requires resection.
    MeSH term(s) Humans ; Early Detection of Cancer ; Pancreatic Neoplasms/diagnosis ; Pancreatic Neoplasms/genetics ; Pancreas ; Neoplastic Syndromes, Hereditary/diagnosis ; Neoplastic Syndromes, Hereditary/genetics ; Pancreatic Neoplasms
    Language German
    Publishing date 2023-02-17
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ISSN 2731-698X
    ISSN (online) 2731-698X
    DOI 10.1007/s00104-023-01819-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Highlights der Pankreaschirurgie: erweiterte Indikationen bei neuroendokrinen Tumoren des Pankreas.

    Oehme, F / Hempel, S / Distler, M / Weitz, J

    Chirurgie (Heidelberg, Germany)

    2022  Volume 93, Issue 8, Page(s) 751–757

    Abstract: Advanced pancreatic neuroendocrine tumors (paNET) are mostly characterized by infiltration of vascular structures and/or neighboring organs. The indications for resection in these cases should be measured based on the possibility of an R0 resection. ... ...

    Title translation Highlights of pancreatic surgery: extended indications in pancreatic neuroendocrine tumors.
    Abstract Advanced pancreatic neuroendocrine tumors (paNET) are mostly characterized by infiltration of vascular structures and/or neighboring organs. The indications for resection in these cases should be measured based on the possibility of an R0 resection. Although the data situation for this rare entity is limited, small case series have shown a significant survival advantage in patients who underwent a radical resection in locally advanced stages of paNET. Both vascular reconstruction and multivisceral resection, when performed at experienced centers, should be considered as curative treatment options. The very special biological behavior of the paNET and the often young patient age justify a much more aggressive approach compared to the pancreatic ductal adenocarcinoma.
    MeSH term(s) Carcinoma, Pancreatic Ductal/surgery ; Humans ; Neuroendocrine Tumors/surgery ; Pancreatectomy ; Pancreatic Neoplasms/surgery ; Pancreaticoduodenectomy
    Language German
    Publishing date 2022-07-05
    Publishing country Germany
    Document type Journal Article ; Review
    ISSN 2731-698X
    ISSN (online) 2731-698X
    DOI 10.1007/s00104-022-01646-3
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  6. Article: Auswirkung der COVID-19-Pandemie auf die Versorgung von Krebserkrankten

    Kirchberg, J. / Weitz, J.

    Krebs im Focus

    2022  Volume 15, Issue Juni, Page(s) 32

    Language German
    Document type Article
    ZDB-ID 2761631-9
    Database Current Contents Medicine

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  7. Article: Moderne Chirurgie des kolorektalen Karzinoms

    Weitz, J. / Fritzmann, J.

    Krebs im Focus

    2022  Volume 16, Issue Dez., Page(s) 10

    Language German
    Document type Article
    ZDB-ID 2761631-9
    Database Current Contents Medicine

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  8. Article ; Conference proceedings: The use of discharge criteria to optimize patient discharge after gastrointestinal operations

    Müssle, B. / Wille, L. / Weitz, J. / Welsch, T.

    Zeitschrift für Gastroenterologie

    2023  Volume 61, Issue 08

    Event/congress Viszeralmedizin 2023 77. Jahrestagung der DGVS mit Sektion Endoskopie Herbsttagung der Deutschen Gesellschaft für Allgemein- und Viszeralchirurgie mit den Arbeitsgemeinschaften der DGAV und Jahrestagung der CACP, Erst online. Dann Hamburg., 2023-09-11
    Language German
    Publishing date 2023-08-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 201387-3
    ISSN 1439-7803 ; 0044-2771 ; 0172-8504
    ISSN (online) 1439-7803
    ISSN 0044-2771 ; 0172-8504
    DOI 10.1055/s-0043-1772112
    Database Thieme publisher's database

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  9. Article ; Online: Evidenz der Roboter-Chirurgie in der onkologischen Viszeralchirurgie.

    Kirchberg, J / Weitz, J

    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen

    2019  Volume 90, Issue 5, Page(s) 379–386

    Abstract: The superiority of minimally invasive operative methods compared to open surgery with respect to various parameters of short-term outcome with adequate oncological long-term results has already been confirmed for many tumor entities in high-quality ... ...

    Title translation Evidence for robotic surgery in oncological visceral surgery.
    Abstract The superiority of minimally invasive operative methods compared to open surgery with respect to various parameters of short-term outcome with adequate oncological long-term results has already been confirmed for many tumor entities in high-quality studies. The continuously expanding robotic surgery offers certain additional benefits in minimally invasive oncological visceral surgery, such as a high-resolution stable 3‑dimensional view, optimal freedom of movement in situ, elimination of natural tremor and better ergonomics. This article evaluates whether these postulated advantages are reflected in an improvement of the short-term perioperative and long-term oncological results compared to conventional minimally invasive surgery in oncological visceral surgery (rectum, colon, stomach, esophagus, pancreas, liver) according to the criteria of evidence-based medicine. With the exception of colorectal surgery, there are currently no randomized controlled studies comparing robotic to laparoscopic surgery in oncological visceral surgery. There is still a clear imbalance between the exponentially expanding application of robotic surgery and the existing lack of high-quality evidence. Further randomized controlled clinical trials urgently need to be performed especially considering the great technological development potential of robotic surgery.
    MeSH term(s) Digestive System Surgical Procedures ; Laparoscopy ; Rectum ; Robotic Surgical Procedures
    Language German
    Publishing date 2019-02-19
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1521-0
    ISSN 1433-0385 ; 0009-4722
    ISSN (online) 1433-0385
    ISSN 0009-4722
    DOI 10.1007/s00104-019-0812-9
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  10. Article ; Online: Prozessmanagement in der Chirurgie.

    Kahlert, C / Janda, M / Weitz, J

    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen

    2021  Volume 92, Issue 3, Page(s) 237–243

    Abstract: Process management is defined as the concept of identifying processes in a company or healthcare organization, analyzing them and improving productivity and efficiency. In hospitals, process management focuses on patient safety, an increase in economic ... ...

    Title translation Process management in surgery.
    Abstract Process management is defined as the concept of identifying processes in a company or healthcare organization, analyzing them and improving productivity and efficiency. In hospitals, process management focuses on patient safety, an increase in economic resources and employee satisfaction. The integration of process management into clinical pathways helps to accelerate workflows and to improve the quality of patient service. The different types of process management encompass the radical concept of process renewal (revolutionary renewal) as well as the concept of evolutionary optimization. Process management in surgery is applied to preoperative, perioperative and postoperative procedures. The development and implementation of evidence-based treatment pathways can help to standardize and structure treatment processes in a surgical department. In this context, the operating room (OR) plays a particularly central role as the most important part of the healthcare provision of perioperative services. Process management is indispensable for the utilization of an optimal OR capacity taking a maximum patient safety and the desired optimal satisfaction of employees into account. The benefits of process management in the OR area are illustrated in an exemplary case study, demonstrating how innovative process management results in an increase of the operation capacity with a simultaneous reduction in costs.
    MeSH term(s) Humans ; Operating Rooms
    Language German
    Publishing date 2021-01-25
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1521-0
    ISSN 1433-0385 ; 0009-4722
    ISSN (online) 1433-0385
    ISSN 0009-4722
    DOI 10.1007/s00104-020-01343-z
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