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  1. Book ; Online: Positionspapier des GKV-Spitzenverbandes für die 19. Legislaturperiode 2017-2021

    Weller, Michael

    Berlin, den 28. Juni 2017

    2017  

    Institution GKV-Spitzenverband
    Author's details GKV-Spitzenverband ; verantwortlich: Michael Weller
    Subject code 610 ; 360
    Language German
    Size 1 Online-Ressource (35 Seiten), Illustrationen
    Edition Stand: Juli 2017
    Publisher GKV-Spitzenverband
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT020137080
    DOI 10.4126/FRL01-006415305
    Database Repository for Life Sciences

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  2. Book ; Online: Europe: pooling strengths, utilising potentials

    Weller, Michael / Eisenbarth, Johannes

    GKV-Spitzenverband’s position statement of 19 March 2019

    2019  

    Institution GKV-Spitzenverband
    Author's details GKV-Spitzenverband ; responsible: Michael Weller, Johannes Eisenbarth
    Subject code 610 ; 360
    Language English
    Size 1 Online-Ressource (21 Seiten), Illustrationen
    Publisher GKV-Spitzenverband
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT020136991
    DOI 10.4126/FRL01-006415315
    Database Repository for Life Sciences

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  3. Book ; Online: Europa: Kräfte bündeln, Potenziale nutzen

    Weller, Michael / Eisenbarth, Johannes

    Positionspapier des GKV-Spitzenverbandes vom 19. März 2019

    2019  

    Institution GKV-Spitzenverband
    Author's details GKV-Spitzenverband ; verantwortlich: Michael Weller, Johannes Eisenbarth
    Subject code 610 ; 360
    Language German
    Size 1 Online-Ressource (21 Seiten), Illustrationen
    Publisher GKV-Spitzenverband
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT020136979
    DOI 10.4126/FRL01-006415317
    Database Repository for Life Sciences

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  4. Book ; Online: Positionspapier des GKV-Spitzenverbandes für die 20. Legislaturperiode 2021–2025

    Weller, Michael / Grunenberg, Markus

    beschlossen vom Verwaltungsrat des GKV-Spitzenverbandes am 23. Juni 2021

    2021  

    Institution GKV-Spitzenverband
    Author's details GKV-Spitzenverband ; verantwortlich: Michael Weller ; Redaktion: Markus Grunenberg, Michael Weller
    Subject code 610 ; 360
    Language German
    Size 1 Online-Ressource (30 Seiten)
    Edition Stand: Juli 2021
    Publisher GKV-Spitzenverband
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT030620179
    DOI 10.4126/FRL01-006472829
    Database Repository for Life Sciences

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  5. Article: The Mystery of Homochirality on Earth.

    Weller, Michael G

    Life (Basel, Switzerland)

    2024  Volume 14, Issue 3

    Abstract: Homochirality is an obvious feature of life on Earth. On the other hand, extraterrestrial samples contain largely racemic compounds. The same is true for any common organic synthesis. Therefore, it has been a perplexing puzzle for decades how these ... ...

    Abstract Homochirality is an obvious feature of life on Earth. On the other hand, extraterrestrial samples contain largely racemic compounds. The same is true for any common organic synthesis. Therefore, it has been a perplexing puzzle for decades how these racemates could have formed enantiomerically enriched fractions as a basis for the origin of homochiral life forms. Numerous hypotheses have been put forward as to how preferentially homochiral molecules could have formed and accumulated on Earth. In this article, it is shown that homochirality of the abiotic organic pool at the time of formation of the first self-replicating molecules is not necessary and not even probable. It is proposed to abandon the notion of a molecular ensemble and to focus on the level of individual molecules. Although the formation of the first self-replicating, most likely homochiral molecule, is a seemingly improbable event, on a closer look, it is almost inevitable that some homochiral molecules have formed simply on a statistical basis. In this case, the non-selective leap to homochirality would be one of the first steps in chemical evolution directly out of a racemic "ocean". Moreover, most studies focus on the chirality of the primordial monomers with respect to an asymmetric carbon atom. However, any polymer with a minimal size that allows folding to a secondary structure would spontaneously lead to asymmetric higher structures (conformations). Most of the functions of these polymers would be influenced by this inherently asymmetric folding. Furthermore, a concept of physical compartmentalization based on rock nanopores in analogy to nanocavities of digital immunoassays is introduced to suggest that complex cell walls or membranes were also not required for the first steps of chemical evolution. To summarize, simple and universal mechanisms may have led to homochiral self-replicating systems in the context of chemical evolution. A homochiral monomer pool is deemed unnecessary and probably never existed on primordial Earth.
    Language English
    Publishing date 2024-03-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life14030341
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online: Echte Arzneimittelinnovationen fördern und die Versorgung stärken

    Haas, Antje / Weller, Michael

    Positionspapier des GKV-Spitzenverbandes zu patentgeschützten Arzneimitteln

    2021  

    Institution GKV-Spitzenverband
    Author's details Herausgeber: GKV-Spitzenverband ; verantwortlich: Dr. Antje Haas, Michael Weller
    Subject code 610 ; 360
    Language German
    Size 1 Online-Ressource (11 Seiten)
    Edition Stand: Juli 2021
    Publisher GKV-Spitzenverband
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT030620529
    DOI 10.4126/FRL01-006472833
    Database Repository for Life Sciences

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  7. Article ; Online: [No title information]

    Weller, Michael

    MMW Fortschritte der Medizin

    2022  Volume 164, Issue 16, Page(s) 28

    Title translation Handys verursachen keine Hirntumoren.
    MeSH term(s) Brain Neoplasms/etiology ; Brain Neoplasms/pathology ; Cell Phone ; Humans
    Language German
    Publishing date 2022-09-16
    Publishing country Germany
    Document type News ; Comment
    ZDB-ID 1478211-x
    ISSN 1613-3560 ; 1438-3276
    ISSN (online) 1613-3560
    ISSN 1438-3276
    DOI 10.1007/s15006-022-1930-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Conference proceedings: Book of abstracts 5th Quadrennial Meeting of the World Federation of Neuro-Oncology Societies (WFNOS)

    Weller, Michael

    May 4-7, 2017, Zurich, Switzerland

    (Neuro-oncology ; volume 19, supplement 3 (May 2017))

    2017  

    Event/congress World Federation of Neuro-Oncology Societies (5., 2017, Zürich, Quadrennial Meeting)
    Author's details co-editors: Michael Weller, Patrick Roth, Ryo Nishikawa, David Reardon
    Series title Neuro-oncology ; volume 19, supplement 3 (May 2017)
    Neuro-Oncology
    Collection Neuro-Oncology
    Language English
    Size iii148 Seiten
    Publisher Oxford University Press
    Publishing place Cary, NC
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT019401849
    Database Catalogue ZB MED Medicine, Health

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  9. Article: Important themes in

    Weller, Michael

    Neuro-oncology practice

    2020  Volume 7, Issue 4, Page(s) 357–358

    Language English
    Publishing date 2020-07-31
    Publishing country England
    Document type Editorial
    ZDB-ID 2768945-1
    ISSN 2054-2585 ; 2054-2577
    ISSN (online) 2054-2585
    ISSN 2054-2577
    DOI 10.1093/nop/npaa036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The Protocol Gap.

    Weller, Michael G

    Methods and protocols

    2021  Volume 4, Issue 1

    Abstract: Although peer review is considered one of the main pillars of modern science, experimental methods and protocols seem to be not a rigorous subject of this process in many papers. Commercial equipment, test kits, labeling kits, previously published ... ...

    Abstract Although peer review is considered one of the main pillars of modern science, experimental methods and protocols seem to be not a rigorous subject of this process in many papers. Commercial equipment, test kits, labeling kits, previously published concepts, and standard protocols are often considered to be not worth a detailed description or validation. Even more disturbing is the extremely biased citation behavior in this context, which sometimes leads to surrogate citations to avoid low-impact journals, preprints, or to indicate traditional practices. This article describes some of these surprising habits and suggests some measures to avoid the most unpleasant effects, which in the long term may undermine the credibility of science as a whole.
    Language English
    Publishing date 2021-02-03
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2409-9279
    ISSN (online) 2409-9279
    DOI 10.3390/mps4010012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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