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  1. Book ; Online ; E-Book: Eosinophil ultrastructure

    Melo, Rossana C. N. / Dvorak, Ann M. / Weller, Peter F.

    Atlas of eosinophil cell biology and pathology

    2022  

    Author's details Rossana C. N. Melo, Ann M. Dvorak, Peter F. Weller
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (xv, 502 Seiten), Illustrationen
    Publisher Elsevier Academic Press
    Publishing place London
    Publishing country Great Britain
    Document type Book ; Online ; E-Book
    Note Description based on publisher supplied metadata and other sources
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021221564
    ISBN 978-0-12-813756-7 ; 9780323994132 ; 0-12-813756-8 ; 032399413X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Tropical infectious diseases

    Guerrant, Richard L. / Walker, David H. / Weller, Peter F.

    principles, pathogens and practice

    (Expert consult)

    2011  

    Author's details Richard L. Guerrant ; David H. Walker ; Peter F. Weller
    Series title Expert consult
    Keywords Tropical Medicine ; Communicable Diseases
    Language English
    Size XXIV, 1130 S. : Ill., graph. Darst., Kt., 28 cm
    Edition 3. ed.
    Publisher Saunders Elsevier
    Publishing place Edinburgh u.a.
    Publishing country Great Britain
    Document type Book
    Accompanying material Zugang zur Internetausgabe über Code
    HBZ-ID HT016785126
    ISBN 978-0-7020-3935-5 ; 0-7020-3935-7
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Audio / Video: Tropical infectious diseases

    Guerrant, Richard L. / Walker, David H. / Weller, Peter F.

    principles, pathogens,& practice

    2006  

    Author's details Guerrant ; Walker ; Weller
    Keywords Tropical Medicine ; Communicable Diseases
    Language English
    Size 1 CD-ROM, 12 cm
    Edition 2. ed.
    Publisher Churchill Livingstone
    Publishing place Philadelphia
    Publishing country United States
    Document type Book ; Audio / Video
    Note Enth.: Bd. 1 - 2
    Remark Handb.: Einzelplatznutzung nur in der ZB MED
    HBZ-ID HT014625568
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Tropical infectious diseases / 1

    Guerrant, Richard L. / Walker, David H. / Weller, Peter F.

    principles, pathogens, & practice

    2006  

    Author's details Richard L. Guerrant ; David H. Walker ; Peter F. Weller
    Collection Tropical infectious diseases
    Language English
    Size Getr. Zählung : zahlr. Ill., graph. Darst., Kt.
    Edition 2. ed.
    Publisher Churchill Livingstone
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT014442465
    ISBN 978-0-443-06668-9 ; 0-443-06668-X
    Database Catalogue ZB MED Medicine, Health

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  5. Book: Tropical infectious diseases / 2

    Guerrant, Richard L. / Walker, David H. / Weller, Peter F.

    principles, pathogens, & practice

    2006  

    Author's details Richard L. Guerrant ; David H. Walker ; Peter F. Weller
    Collection Tropical infectious diseases
    Language English
    Size XXVII S., S. 884 - 1721, 65 S. : zahlr. Ill., graph. Darst., Kt.
    Edition 2. ed.
    Publisher Churchill Livingstone
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT014442478
    ISBN 978-0-443-06668-9 ; 0-443-06668-X
    Database Catalogue ZB MED Medicine, Health

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  6. Article: LEUKOCYTE LIPID BODIES - STRUCTURE AND FUNCTION AS "EICOSASOMES".

    Weller, Peter F

    Transactions of the American Clinical and Climatological Association

    2017  Volume 127, Page(s) 328–340

    Abstract: Lipid bodies are cytoplasmic inclusions that develop within leukocytes, including eosinophils and neutrophils, associated with inflammation. Our investigations of the formation and function of lipid bodies have revealed that they are distinct, inducible ... ...

    Abstract Lipid bodies are cytoplasmic inclusions that develop within leukocytes, including eosinophils and neutrophils, associated with inflammation. Our investigations of the formation and function of lipid bodies have revealed that they are distinct, inducible endoplasmic reticulum-derived, membrane- and ribosome-containing organelles with diverse functional roles in inflammatory responses of leukocytes. Leukocyte lipid bodies contain all enzymes required for synthesizing cyclo-oxygenase- and lipoxygenase-derived eicosanoids. Lipid body formation, rapidly inducible
    MeSH term(s) Animals ; Arachidonic Acid/biosynthesis ; Eicosanoids/biosynthesis ; Leukocytes/cytology ; Lipid Droplets/physiology ; Signal Transduction
    Chemical Substances Eicosanoids ; Arachidonic Acid (27YG812J1I)
    Language English
    Publishing date 2017-01-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603823-2
    ISSN 0065-7778
    ISSN 0065-7778
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: In Reply-Are Eosinophils Needed for Normal Health?

    Wechsler, Michael E / Ackerman, Steven J / Weller, Peter F

    Mayo Clinic proceedings

    2022  Volume 97, Issue 4, Page(s) 805–807

    MeSH term(s) Eosinophils ; Humans ; Leukocyte Count
    Language English
    Publishing date 2022-01-31
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2022.01.037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Biologics and Hypereosinophilic Syndromes: Knowledge Gaps and Controversies.

    Kuang, Fei Li / Khoury, Paneez / Weller, Peter F / Wechsler, Michael E / Klion, Amy D

    The journal of allergy and clinical immunology. In practice

    2023  Volume 11, Issue 9, Page(s) 2666–2671

    Abstract: Hypereosinophilic syndromes (HES) are a heterogeneous group of disorders defined by blood and/or tissue hypereosinophilia and clinical manifestations attributable to the eosinophilia. Although various clinical subtypes of HES have been described, the ... ...

    Abstract Hypereosinophilic syndromes (HES) are a heterogeneous group of disorders defined by blood and/or tissue hypereosinophilia and clinical manifestations attributable to the eosinophilia. Although various clinical subtypes of HES have been described, the general approach to therapy in all subtypes has focused on the reduction of blood and tissue eosinophilia to improve symptoms and halt disease progression. Until recently, this typically involved the use of corticosteroids and/or other immunosuppressive or cytotoxic drugs with significant toxicity. Whereas imatinib, the first targeted therapy approved for treatment of HES, has dramatically changed the prognosis of patients with primary (myeloid) forms of HES, it is ineffective in patients with other HES subtypes. For these nonmyeloid patients with HES, the development of eosinophil-targeting biologics (most notably, mepolizumab, the first biologic approved for the treatment of HES) has been transformative. Nevertheless, important issues remain with respect to the efficacy and safety of these biologics in the treatment of the varied subtypes of HES. Moreover, with the increasing number of commercially available biologics with direct or indirect effects on eosinophils, questions related to the choice of initial biologic, potential reasons for biologic failure, and treatment options in the setting of incomplete response are becoming increasingly common.
    MeSH term(s) Humans ; Antineoplastic Agents/therapeutic use ; Imatinib Mesylate/therapeutic use ; Biological Factors/therapeutic use ; Hypereosinophilic Syndrome/drug therapy ; Hypereosinophilic Syndrome/diagnosis ; Biological Products/therapeutic use
    Chemical Substances Antineoplastic Agents ; Imatinib Mesylate (8A1O1M485B) ; Biological Factors ; Biological Products
    Language English
    Publishing date 2023-07-26
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2023.07.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Collection: Tropical infectious diseases

    Guerrant, Richard L. / Walker, David H. / Weller, Peter F.

    principles, pathogens, & practice

    1999  

    Author's details Richard L. Guerrant ; David H. Walker ; Peter F. Weller
    Keywords Tropical Medicine ; Communicable Diseases
    Language English
    Dates of publication 1999-9999
    Publisher Churchill Livingstone
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book ; Collection (display volumes)
    Note CD-ROM-Ausg. zur 2. Aufl.
    HBZ-ID HT011123517
    ISBN 978-0-443-06668-9 ; 0-443-07908-0 ; 0-443-06668-X ; 978-0-443-07908-5
    Database Catalogue ZB MED Medicine, Health

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  10. Book: Tropical infectious diseases / 1

    Guerrant, Richard L. / Walker, David H. / Weller, Peter F.

    principles, pathogens, & practice

    1999  

    Author's details Richard L. Guerrant ; David H. Walker ; Peter F. Weller
    Collection Tropical infectious diseases
    Language English
    Size XXIII, 824, LX S. : Ill., graph. Darst., Kt.
    Edition 1. Aufl.
    Publisher Churchill Livingstone
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT011123564
    ISBN 9-997-63292-3 ; 978-9-997-63292-0
    Database Catalogue ZB MED Medicine, Health

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