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  1. Article ; Online: Extraction of landslide morphology based on Topographic Profile along the Direction of Slope Movement using UAV images

    Yujie Zhang / Jia Li / Jiajia Liu / Wenbin Xie / Ping Duan

    Geomatics, Natural Hazards & Risk, Vol 14, Iss

    2023  Volume 1

    Abstract: AbstractThe landslide morphology is quickly and accurately extracted from Unmanned Air Vehicle (UAV) images. It is of great significance for emergency rescue and quantitative evaluation of landslide disasters. However, due to the complexity of landslide ... ...

    Abstract AbstractThe landslide morphology is quickly and accurately extracted from Unmanned Air Vehicle (UAV) images. It is of great significance for emergency rescue and quantitative evaluation of landslide disasters. However, due to the complexity of landslide morphology, choosing the reasonable extraction thresholds is a challenging issue. A threshold selection method of Topographic Profile along the Direction of Slope Movement (TP-DSM) was proposed. Firstly, a hierarchical extraction rule sets for landslide morphology was constructed by integrating multi-feature information such as spectral, texture, geometry, topography and space of UAV images. Second, TP-DSM was proposed to select the optimal elevation thresholds for classifying different landslide morphology. Finally, the thresholds were introduced into the rule sets to achieve effective extraction of landslide morphology. This study uses Digital Orthophoto Map (DOM) and Digital Elevation Model (DEM) generated by UAV images as data sources, and the landslide in Luquan County, Yunnan Province, China as the Study area, the results show that the overall accuracy (OA) of landslide morphology extraction was 89.58%, and the Kappa coefficient was 0.88, which is effective and more consistent with the reality. The proposed method can also be applied to other potential locations.
    Keywords UAV images ; multi-feature information ; TP-DSM ; landslide morphology ; Environmental technology. Sanitary engineering ; TD1-1066 ; Environmental sciences ; GE1-350 ; Risk in industry. Risk management ; HD61
    Subject code 550
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Taylor & Francis Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Metabolomics and Network Pharmacology-Based Investigation into the Mechanisms Underlying the Therapeutic Effect of a New Chinese Traditional Medicine (Cui Nai Ling) on Bromocriptine-Induced Hypogalactia

    Xianglong Meng / Chenzi Lyu / Junnan Ma / Xiaoyan Zhang / Cong Hu / Xiaojuan Su / Chenxu Ning / Wenbin Xie / Shuosheng Zhang

    Evidence-Based Complementary and Alternative Medicine, Vol

    2021  Volume 2021

    Abstract: As a traditional veterinary medicine to promote lactation, Cui Nai Ling (CNL) can not only increase milk supply and promote health but also improve the overall physiological function and immunity of the animals. In order to further improve CNL’s effect ... ...

    Abstract As a traditional veterinary medicine to promote lactation, Cui Nai Ling (CNL) can not only increase milk supply and promote health but also improve the overall physiological function and immunity of the animals. In order to further improve CNL’s effect on lactation, we have previously made a new CNL (NCNL) by adding Tetrapanacis Medulla and replacing Vaccariae Semen with fried Vaccariae Semen in CNL. We have demonstrated that the lactation-promoting effect of NCNL is better than that of CNL. However, the underlying mechanisms by which NCNL promotes lactation are unclear. In this study, we performed metabolomics, network pharmacology, and pharmacodynamic studies to explore the underlying mechanisms by which NCNL promotes lactation in rats with bromocriptine-induced hypogalactia. The results showed that NCNL significantly improved the loss of appetite in female adult rats and the weight loss of pups caused by the disorder of lactation. Biochemical analysis showed that NCNL could regulate the levels of PRL, T4, E2, Ca, UREA, GLU, ALT, AST, TCHO, and TG in serum. The pathological results showed that NCNL could promote lactation and increase the mammary gland index by improving breast acinar tissue morphology in rats with hypogalactia. Network pharmacology studies showed that NCNL promotes lactation through P13K-Akt, insulin resistance, and prolactin signaling pathways, among which the most frequently affected pathway was the P13K-Akt signaling pathway. Metabolomics studies showed that NCNL can significantly upregulate phenylalanine, tyrosine, and tryptophan biosynthesis and tyrosine metabolism pathways and downregulate cysteine and methionine metabolism pathways. NCNL can significantly increase the serum prolactin concentration, improve the glucose and lipid metabolism disorders, and regulate PI3K-Akt, insulin resistance, and prolactin pathways to affect the amino acids’ metabolism in the mammary gland and ultimately exert its therapeutic effect on bromocriptine-induced postpartum hypogalactia. These findings ...
    Keywords Other systems of medicine ; RZ201-999
    Subject code 630
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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