LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Your last searches

  1. AU="Weng, Wei-Chien"
  2. AU="Michael Zauner"
  3. AU="Offin, M."
  4. AU=Burney Ikram A
  5. AU="Sciubba, Adalberto"
  6. AU="Hu, Tony Y"
  7. AU="L'Hoyes, Wouter"
  8. AU="Bernhardt, Sarah M"
  9. AU="Holman, Wayne"
  10. AU="Ghabi, Elie"
  11. AU="Pan, Jia-fu"
  12. AU="Fareed, Zeeshan"
  13. AU="Watkins, A Claire"
  14. AU="Taggart, Michael"
  15. AU="Boone, William J"

Search results

Result 1 - 4 of total 4

Search options

  1. Article ; Online: Development of a Cloud-Based Image Processing Health Checkup System for Multi-Item Urine Analysis.

    Wu, Yu-Lin / Wang, Chien-Shun / Weng, Wei-Chien / Lin, Yu-Cheng

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 18

    Abstract: With the busy pace of modern life, an increasing number of people are afflicted by lifestyle diseases. Going directly to the hospital for medical checks is not only time-consuming but also costly. Fortunately, the emergence of rapid tests has alleviated ... ...

    Abstract With the busy pace of modern life, an increasing number of people are afflicted by lifestyle diseases. Going directly to the hospital for medical checks is not only time-consuming but also costly. Fortunately, the emergence of rapid tests has alleviated this burden. Accurately interpreting test results is extremely important; misinterpreting the results of rapid tests could lead to delayed medical treatment. Given that URS-10 serve as a rapid test capable of detecting 10 distinct parameters in urine samples, the results of assessing these parameters can offer insights into the subject's physiological condition. These parameters encompass aspects such as metabolism, renal function, diabetes, urinary tract disorders, hemolytic diseases, and acid-base balance, among others. Although the operational procedure is straightforward, the variegated color changes exhibited in the outcomes of individual parameters render it challenging for lay users to deduce causal factors solely from color variations. Moreover, potential misinterpretations could arise due to visual discrepancies. In this study, we successfully developed a cloud-based health checkup system that can be used in an indoor environment. The system is used by placing a URS-10 test strip on a colorimetric board developed for this study, then using a smartphone application to take images which are uploaded to a server for cloud computing. Finally, the interpretation results are stored in the cloud and sent back to the smartphone to be checked by the user. Furthermore, to confirm whether the color calibration technology can eliminate color differences between different cameras, and also whether the colorimetric board and the urine test strips can perform color comparisons correctly in different light intensity environments, indoor environments that could simulate a specific light intensity were established for testing purposes. When comparing the experimental results to real test strips, only two groups failed to reach an identification success rate of 100%, and in both of these cases the success rate reached 95%. The experimental results confirmed that the system developed in this study was able to eliminate color differences between camera devices and could be used without special technical requirements or training.
    Language English
    Publishing date 2023-09-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23187733
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Unusual free oligosaccharides in human bovine and caprine milk.

    Weng, Wei-Chien / Liao, Hung-En / Huang, Shih-Pei / Tsai, Shang-Ting / Hsu, Hsu-Chen / Liew, Chia Yen / Gannedi, Veeranjaneyulu / Hung, Shang-Cheng / Ni, Chi-Kung

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 10790

    Abstract: Free oligosaccharides are abundant macronutrients in milk and involved in prebiotic functions and antiadhesive binding of viruses and pathogenic bacteria to colonocytes. Despite the importance of these oligosaccharides, structural determination of ... ...

    Abstract Free oligosaccharides are abundant macronutrients in milk and involved in prebiotic functions and antiadhesive binding of viruses and pathogenic bacteria to colonocytes. Despite the importance of these oligosaccharides, structural determination of oligosaccharides is challenging, and milk oligosaccharide biosynthetic pathways remain unclear. Oligosaccharide structures are conventionally determined using a combination of chemical reactions, exoglycosidase digestion, nuclear magnetic resonance spectroscopy, and mass spectrometry. Most reported free oligosaccharides are highly abundant and have lactose at the reducing end, and current oligosaccharide biosynthetic pathways in human milk are proposed based on these oligosaccharides. In this study, a new mass spectrometry technique, which can identify linkages, anomericities, and stereoisomers, was applied to determine the structures of free oligosaccharides in human, bovine, and caprine milk. Oligosaccharides that do not follow the current biosynthetic pathways and are not synthesized by any discovered enzymes were found, indicating the existence of undiscovered biosynthetic pathways and enzymes.
    MeSH term(s) Animals ; Cattle ; Goats/metabolism ; Humans ; Lactose/metabolism ; Milk/chemistry ; Milk, Human/chemistry ; Oligosaccharides/metabolism ; Prebiotics/analysis
    Chemical Substances Oligosaccharides ; Prebiotics ; Lactose (J2B2A4N98G)
    Language English
    Publishing date 2022-06-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-15140-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Automatic Full Glycan Structural Determination through Logically Derived Sequence Tandem Mass Spectrometry.

    Tsai, Shang-Ting / Liew, Chia Yen / Hsu, Chen / Huang, Shih-Pei / Weng, Wei-Chien / Kuo, Yu-Hsiang / Ni, Chi-Kung

    Chembiochem : a European journal of chemical biology

    2019  Volume 20, Issue 18, Page(s) 2351–2359

    Abstract: Glycans have diverse functions and play vital roles in many biological systems, such as influenza, vaccines, and cancer biomarkers. However, full structural identification of glycans remains challenging. The glycan structure was conventionally determined ...

    Abstract Glycans have diverse functions and play vital roles in many biological systems, such as influenza, vaccines, and cancer biomarkers. However, full structural identification of glycans remains challenging. The glycan structure was conventionally determined by chemical methods or NMR spectroscopy, which require a large amount of sample and are not readily applicable for glycans extracted from biological samples. Although it has high sensitivity and is widely used for structural determination of molecules, current mass spectrometry can only reveal parts of the glycan structure. Herein, the full structures of glycans, including diastereomers, the anomericity of each monosaccharide, and the linkage position of each glycosidic bond, which can be determined by using tandem mass spectrometry guided by a logically derived sequence (LODES), are shown. This new method provides de novo oligosaccharide structural identification with high sensitivity and has been applied to automatic in situ structural determination of oligosaccharides eluted by means of HPLC. It is shown that the structure of a given trisaccharide from a trisaccharide mixture and bovine milk were determined from nearly 3000 isomers by using 6-7 logically selected collision-induced dissociation spectra. The entire procedure for mass spectrometry measurement guided by LODES can be programmed in a computer for automatic full glycan structure identification.
    MeSH term(s) Animals ; Carbohydrate Sequence ; Milk/chemistry ; Oligosaccharides/analysis ; Oligosaccharides/chemistry ; Polysaccharides/analysis ; Polysaccharides/chemistry ; Tandem Mass Spectrometry/methods
    Chemical Substances Oligosaccharides ; Polysaccharides
    Language English
    Publishing date 2019-08-01
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2020469-3
    ISSN 1439-7633 ; 1439-4227
    ISSN (online) 1439-7633
    ISSN 1439-4227
    DOI 10.1002/cbic.201900228
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Book ; Article ; Online: Mass Reproducibility and Replicability

    Brodeur, Abel / Mikola, Derek / Cook, Nikolai / Brailey, Thomas / Briggs, Ryan / de Gendre, Alexandra / Dupraz, Yannick / Fiala, Lenka / Gabani, Jacopo / Gauriot, Romain / Haddad, Joanne / Kjellsson, Gustav / Kjelsrud, Anders / Kotsadam, Andreas / Korpershoek, Jori / Krashinsky, Lewis / Kundu, Suranjana / Kustov, Alexander / Lalayev, Nurlan /
    Langlois, Audrée / Wright, Taylor / Duncan, Jamie / Laufer, Jill / Lee-Whiting, Blake / Leibing, Andreas / Lenz, Gabriel / Levin, Joel / Li, Peng / Li, Tongzhe / Lin, Yuchen / Listo, Ariel / Liu, Dan / Duong, Kiet Tuan / Connolly, Marie / Lu, Xuewen / Lukmanova, Elvina / Luscombe, Alex / Lusher, Lester R. / Lyu, Ke / Ma, Hai / Mäder, Nicolas / Makate, Clifton / Malmberg, Alice / Duprey, Thibaut / Maitra, Adit / Hoces de la Guardia, Fernando / Mandas, Marco / Marcus, Jan / Margaryan, Shushanik / Márk, Lili / Martignano, Andres / Marsh, Abigail / Masetto, Isabella / McCanny, Anthony / Dworschak, Christoph / McManus, Emma / McWay, Ryan / Johannesson, Magnus / Metson, Lennard / Kinge, Jonas Minet / Mishra, Sumit / Mohnen, Myra / Möller, Jakob / Montambeault, Rosalie / Montpetit, Sébastien / Ellingsrud, Sigmund / Morin, Louis-Philippe / Morris, Todd / Moser, Scott / Miguel, Edward / Motoki, Fabio / Muehlenbachs, Lucija / Musulan, Andreea / Musumeci, Marco / Nabin, Munirul / Nchare, Karim / Elminejad, Ali / Neubauer, Florian / Nguyen, Quan M. P. / Nguyen, Tuan / Nguyen-Tien, Viet / Vilhuber, Lars / Niazi, Ali / Nikolaishvili, Giorgi / Nordstrom, Ardyn / Nüß, Patrick / Odermatt, Angela / Eissa, Yasmine / Olson, Matt / Øien, Henning / Ölkers, Tim / Oliver i Vert, Miquel / Oral, Emre / Abarca, Alejandro / Oswald, Christian / Ousman, Ali / Özak, Ömer / Pandey, Shubham / Erhart, Andrea / Pavlov, Alexandre / Pelli, Martino / Penheiro, Romeo / Park, RyuGyung / Pérez Martel, Eva / Petrovičová, Tereza / Acharya, Mahesh / Phan, Linh / Prettyman, Alexa / Procházka, Jakub / Etingin-Frati, Giulian / Putri, Aqila / Quandt, Julian / Qiu, Kangyu / Nguyen, Loan Quynh Thi / Rahman, Andaleeb / Rea, Carson H. / Reiremo, Adam / Adjisse, Sossou Simplice / Renée, Laëtitia / Richardson, Joseph / Fatemi-Pour, Elaheh / Rivers, Nicholas / Rodrigues, Bruno / Roelofs, William / Roemer, Tobias / Rogeberg, Ole / Rose, Julian / Roskos-Ewoldsen, Andrew / Rosmer, Paul / Akhtar, Ahwaz / Sabada, Barbara / Lima, Goncalo / Saberian, Soodeh / Salamanca, Nicolas / Sator, Georg / Sawyer, Antoine / Scates, Daniel / Schlüter, Elmar / Sells, Cameron / Sen, Sharmi / Sethi, Ritika / Ramirez Lizardi, Eduardo Alberto / Federice, Alexa / Shcherbiak, Anna / Sogaolu, Moyosore / Soosalu, Matt / Sørensen, Erik Ø. / Sovani, Manali / Spencer, Noah / Staubli, Stefan / Stans, Renske / Stewart, Anya / Stips, Felix / Feld, Jan / Albrecht, Sabina / Stockley, Kieran / Strobel, Stephenson / Struby, Ethan / Tang, John / Tanrisever, Idil / Yang, Thomas Tao / Tastan, Ipek / Tatić, Dejan / Tatlow, Benjamin / Fenig, Guidon / Tchuisseu Seuyong, Féraud / Andersen, Synøve Nygaard / Thériault, Rémi / Thivierge, Vincent / Tian, Wenjie / Toma, Filip-Mihai / Totarelli, Maddalena / Tran, Van-Anh / Truong, Hung / Tsoy, Nikita / Firouzjaeiangalougah, Mojtaba / Tuzcuoglu, Kerem / Ubfal, Diego / Andlib, Zubaria / Villalobos, Laura / Walterskirchen, Julian / Wang, Joseph Taoyi / Wattal, Vasudha / Webb, Matthew D. / Weber, Bryan / Weisser, Reinhard / Fleisje, Erlend / Weng, Wei-Chien / Westheide, Christian / White, Kimberly / Arrora, Falak / Winter, Jacob / Wochner, Timo / Woerman, Matt / Wong, Jared / Woodard, Ritchie / Wroński, Marcin / Fortier-Chouinard, Alexandre / Yazbeck, Myra / Yang, Gustav Chung / Yap, Luther / Yassin, Kareman / Ash, Thomas / Ye, Hao / Yoon, Jin Young / Yurris, Chris / Zahra, Tahreen / Zaneva, Mirela / Engel, Julia Francesca / Zayat, Aline / Zhang, Jonathan / Zhao, Ziwei / Zhong Yaolang / Bacher, Etienne / Bachler, Sebastian / Bacon, Félix / Bagues, Manuel / Balogh, Timea / Batmanov, Alisher / Fries, Tilman / Barschkett, Mara / Basdil, B. Kaan / Baxa, Jaromír / Becker, Sascha / Beeder, Monica / Beland, Louis-Philippe / Bello, Abdel Hamid / Markovits, Daniel Benenson / Benjamin, Grant / Bergeron, Thomas / Fortier, Reid / Blimpo, Moussa P. / Binetti, Marco / Bonander, Carl / Bonneau, Joseph / Borbáth, Endre / Topstad Borgen, Nicolai / Topstad Borgen, Solveig / Borowsky, Jonathan / Brini, Elisa / Brown, Myriam / Fréchet, Nadjim / Brun, Martín / Bruns, Stephan / Buliskeria, Nino / Calef, Andrea / Cameron, Alistair / Campa, Pamela / Campos-Rodríguez, Santiago / Cantone, Giulio Giacomo / Carpena, Fenella / Carter, Perry / Ankel-Peters, Jörg / Castañeda Dower, Paul / Castek, Ondrej / Caviglia-Harris, Jill / Chauca Strand, Gabriella / Chen, Shi / Chzhen, Asya / Chung, Jong / Collins, Jason / Coppock, Alexander / Cordeau, Hugo / Galipeau, Thomas / Couillard, Ben / Crechet, Jonathan / Crippa, Lorenzo / Cui, Jeanne / Czymara, Christian / Daarstad, Haley / Dao, Danh Chi / Dao, Dong / Schmandt, Marco David / de Linde, Astrid / Gallegos, Sebastián / De Melo, Lucas / Deer, Lachlan / De Vera, Micole / Dimitrova, Velichka / Dollbaum, Jan Fabian / Dollbaum, Jan Matti / Donnelly, Michael / Huynh, Luu Duc Toan / Dumbalska, Tsvetomira / Gangji, Areez / Gao, Xiaoying / Garnache, Cloé / Gáspár, Attila / Gavrilova, Evelina / Ghosh, Arijit / Gibney, Garreth / Gibson, Grant / Dreber, Anna / Godager, Geir / Goff, Leonard / Gong, Da / González, Javier / Gretton, Jeremy / Griffa, Cristina / Grigoryeva, Idaliya / Grøtting, Maja / Guntermann, Eric / Guo, Jiaqi / Campbell, Douglas / Gugushvili, Alexi / Habibnia, Hooman / Häffner, Sonja / Hall, Jonathan D. / Hammar, Olle / Kordt, Amund Hanson / Hashimoto, Barry / Hartley, Jonathan S. / Hausladen, Carina I. / Havránek, Tomáš / Kattan, Lamis / Hazen, Jacob / He, Harry / Hepplewhite, Matthew / Herrera-Rodriguez, Mario / Heuer, Felix / Heyes, Anthony / Ho, Anson T. Y. / Holmes, Jonathan / Holzknecht, Armando / Hsu, Yu-Hsiang Dexter / Marino Fages, Diego / Hu, Shiang-Hung / Huang, Yu-Shiuan / Huebener, Mathias / Huber, Christoph / Huynh, Kim P. / Irsova, Zuzana / Isler, Ozan / Jakobsson, Niklas / Frith, Michael James / Jananji, Raphaël / Mierisch, Fabian / Jayalath, Tharaka A. / Jetter, Michael / John, Jenny / Forshaw, Rachel Joy / Juan, Felipe / Kadriu, Valon / Karim, Sunny / Kelly, Edmund / Dang, Duy Khanh Hoang / Khushboo, Tazia / Sun, Pu / Kim, Jin

    A New Hope

    2024  

    Abstract: This study pushes our understanding of research reliability by reproducing and replicating claims from 110 papers in leading economic and political science journals. The analysis involves computational reproducibility checks and robustness assessments. ... ...

    Abstract This study pushes our understanding of research reliability by reproducing and replicating claims from 110 papers in leading economic and political science journals. The analysis involves computational reproducibility checks and robustness assessments. It reveals several patterns. First, we uncover a high rate of fully computationally reproducible results (over 85%). Second, excluding minor issues like missing packages or broken pathways, we uncover coding errors for about 25% of studies, with some studies containing multiple errors. Third, we test the robustness of the results to 5,511 re-analyses. We find a robustness reproducibility of about 70%. Robustness reproducibility rates are relatively higher for re-analyses that introduce new data and lower for re-analyses that change the sample or the definition of the dependent variable. Fourth, 52% of re-analysis effect size estimates are smaller than the original published estimates and the average statistical significance of a re-analysis is 77% of the original. Lastly, we rely on six teams of researchers working independently to answer eight additional research questions on the determinants of robustness reproducibility. Most teams find a negative relationship between replicators' experience and reproducibility, while finding no relationship between reproducibility and the provision of intermediate or even raw data combined with the necessary cleaning codes.
    Keywords ddc:330 ; B41 ; C10 ; C81 ; Reproduction ; Replication ; Research Transparency ; Open Science ; Economics ; Political Science
    Subject code 001
    Language English
    Publisher s.l.: Institute for Replication (I4R)
    Publishing country de
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

To top