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Article ; Online: The relationship between pre-landfall intensity change and post-landfall weakening of tropical cyclones over China

Wenjun Han / Yuqing Wang / Lu Liu

Frontiers in Earth Science, Vol

2022 Volume 10

Abstract: The accurate prediction of the weakening of landfalling tropical cyclones (TC) is of great importance to the disaster prevention but is still challenging. In this study, based on the 6-hourly TC best-track data and global reanalysis data, the ... ...

Abstract	The accurate prediction of the weakening of landfalling tropical cyclones (TC) is of great importance to the disaster prevention but is still challenging. In this study, based on the 6-hourly TC best-track data and global reanalysis data, the relationship between the intensity change prior to landfall of TCs and the energy dissipation rate after landfall over mainland China is statistically analyzed, and the difference between East and South China is compared. Results show that TCs making landfall over East China often experienced pre-landfall weakening and usually corresponded to a rapid decay after landfall, while most TCs making landfall over South China intensified prior to landfall and weakened slowly after landfall. The key factors affecting both pre-landfall intensity change and post-landfall energy dissipation rate are quantitatively analyzed. It is found that the decreasing sea surface temperature (SST), increasing SST gradient, and increasing environmental vertical wind shear are the major factors favoring high pre-landfall weakening occurrence, leading to rapid TC weakening after landfall over East China. In South China, changes in the large-scale environmental factors are relatively small and contribute little to the post-landfall weakening rate.
Keywords	landfalling tropical cyclones ; intensity change ; post-landfall weakening rate ; large-scale environmental factors ; statistical analysis ; Science ; Q
Subject code	950
Language	English
Publishing date	2022-12-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Electroacupuncture stimulating Zhongji (CV3), Guanyuan (CV4), and bilateral Dahe (KI12) attenuates inflammation in rats with chronic nonbacterial prostatitis induced by estradiol through inhibiting toll-like receptor 4 pathway.

Zhihao, L I / Wenjun, Han / Xiuling, Song / Yan, L I / Yuelai, Chen

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan

2023 Volume 43, Issue 5, Page(s) 963–972

Abstract: Objective: To investigate the anti-inflammatory effect of electroacupuncture (EA) on chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), also known as chronic nonbacterial prostatitis (CNP), and explore its underlying mechanism.: Methods: A ... ...

Abstract	Objective: To investigate the anti-inflammatory effect of electroacupuncture (EA) on chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), also known as chronic nonbacterial prostatitis (CNP), and explore its underlying mechanism. Methods: A CNP rat was established by surgical castration combined with 17-β estradiol injection in male Sprague-Dawley rats for thirty consecutive days. The CNP rats received EA treatment once a day for eight days. Chronic pelvic pain was evaluated by mechanical withdrawal threshold measurement. The histological change was assessed by hematoxylin-eosin staining. The inflammatory cytokines in prostates were determined by enzyme-linked immunosorbent assays. The expressions of toll-like receptor 4 (TLR4), myeloid differentiation factor 88 (MyD88), inhibitors of kappa-B alpha (IκBα), and nuclear factor-kappa B (NF-κB) were detected by Western blotting. The nuclear translocation of NF-κB and the location of TLR4 were observed with immunofluorescence staining. Results: The results showed that EA decreased the prostate index, upregulated the mechanical withdrawal threshold, restored the histomorphology of the prostate, reduced the inflammatory factor levels, inhibited NF-κB p65 nuclear translocation, and downregulated the expression levels of critical proteins involved in the TLR4/NF-κB signaling pathway in prostates. Conclusions: Our findings suggested that EA could relieve pelvic pain and attenuate prostatic inflammation in estradiol-induced CNP rats. The underlying mechanism may be related to the inhibition of the TLR4/NF-κB signaling pathway.
MeSH term(s)	Male ; Rats ; Animals ; Humans ; Prostatitis/drug therapy ; Prostatitis/genetics ; Toll-Like Receptor 4/genetics ; Electroacupuncture ; NF-kappa B/genetics ; Rats, Sprague-Dawley ; Inflammation ; Estradiol
Chemical Substances	Toll-Like Receptor 4 ; NF-kappa B ; Estradiol (4TI98Z838E)
Language	English
Publishing date	2023-09-07
Publishing country	China
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	603186-9
ISSN	2589-451X ; 0254-6272 ; 0255-2922
ISSN (online)	2589-451X ; 0254-6272
ISSN	0255-2922
DOI	10.19852/j.cnki.jtcm.20230608.001
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Comparison of Biochemical Characteristics, Action Models, and Enzymatic Mechanisms of a Novel Exolytic and Two Endolytic Lyases with Mannuronate Preference

Lianghuan Zeng / Junge Li / Yuanyuan Cheng / Dandan Wang / Jingyan Gu / Fuchuan Li / Wenjun Han

Marine Drugs, Vol 19, Iss 706, p

2021 Volume 706

Abstract: Recent explorations of tool-like alginate lyases have been focused on their oligosaccharide-yielding properties and corresponding mechanisms, whereas most were reported as endo-type with α-L-guluronate (G) preference. Less is known about the β-D- ... ...

Abstract	Recent explorations of tool-like alginate lyases have been focused on their oligosaccharide-yielding properties and corresponding mechanisms, whereas most were reported as endo-type with α-L-guluronate (G) preference. Less is known about the β-D-mannuronate (M) preference, whose commercial production and enzyme application is limited. In this study, we elucidated Aly6 of Flammeovirga sp. strain MY04 as a novel M-preferred exolytic bifunctional lyase and compared it with AlgLs of Pseudomonas aeruginosa (Pae-AlgL) and Azotobacter vinelandii (Avi-AlgL), two typical M-specific endolytic lyases. This study demonstrated that the AlgL and heparinase_II_III modules play indispensable roles in determining the characteristics of the recombinant exo-type enzyme rAly6, which is preferred to degrade M-enriched substrates by continuously cleaving various monosaccharide units from the nonreducing end, thus yielding various size-defined ΔG-terminated oligosaccharides as intermediate products. By contrast, the endolytic enzymes Pae-rAlgL and Avi-rAlgL varied their action modes specifically against M-enriched substrates and finally degraded associated substrate chains into various size-defined oligosaccharides with a succession rule, changing from ΔM to ΔG-terminus when the product size increased. Furthermore, site-directed mutations and further protein structure tests indicated that H 195 NHSTW is an active, half-conserved, and essential enzyme motif. This study provided new insights into M-preferring lyases for novel resource discoveries, oligosaccharide preparations, and sequence determinations.
Keywords	action mode ; catalytic mechanism ; gene truncation ; oligosaccharide-yielding property ; protein-structure modeling ; Biology (General) ; QH301-705.5
Subject code	572
Language	English
Publishing date	2021-12-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Opposing and Operated Side Electroacupuncture Generates Similar Analgesic Effects on Pain after Knee Surgery

Hai Huang / Xiuling Song / Jiayou Wang / Man Xing / Bingxin Kang / Chenghao Ma / Wenbiao Li / Wenjun Han / Lianbo Xiao / Yuelai Chen

Evidence-Based Complementary and Alternative Medicine, Vol

2021 Volume 2021

Abstract: The purpose of this study was to investigate whether opposing electroacupuncture (EA) could produce similar analgesic effects as operated side EA after knee surgery in rats. Sprague Dawley rats were randomly divided into the sham surgery group, and three ...

Abstract	The purpose of this study was to investigate whether opposing electroacupuncture (EA) could produce similar analgesic effects as operated side EA after knee surgery in rats. Sprague Dawley rats were randomly divided into the sham surgery group, and three surgery groups: opposing EA, operated side EA, and model. After surgery, compared with the sham surgery group, three kinds of pain behavior test methods (mechanical withdrawal threshold (MWT), cumulative pain score [CPS], and mechanical hypersensitivity of knee) were used to assess the pain behavior of the rats in the surgery groups. After knee surgery, the three surgery groups were intervened for three consecutive days: EA on the nonoperated side in the opposing EA group, EA on the operated side in the operated side EA group, and no intervention in the model group. It was shown that MWT was higher and CPS was lower in the two EA groups than in the model group on the first and second days after surgery. On the third day after surgery, MWT in the two EA groups was the highest among the 3 days, CPS was the lowest among the 3 days, and the number of nonvocalizations in rats also increased compared with the model group. Moreover, the MWT of the nonoperated side increased more in the opposing EA group than in the model and operated side EA groups. This indicated that both opposing EA and operated side EA methods can be used to relieve pain after knee joint surgery.
Keywords	Other systems of medicine ; RZ201-999
Subject code	796
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Sheng Jing Decoction Can Promote Spermatogenesis and Increase Sperm Motility of the Oligozoospermia Mouse Model

Guang Yan / Fang Tian / Peng Liu / Jianming Sun / Jianmin Mao / Wenjun Han / Ran Mo / Shishuai Guo / Quanyao Yu

Evidence-Based Complementary and Alternative Medicine, Vol

2021 Volume 2021

Abstract: Sheng Jing Decoction (SJD), as a traditional Chinese medicine prescription, is mainly be used to treat male infertility. However, the pharmacological functions and molecular mechanisms of SJD are poorly understood. In this study, we investigated the ... ...

Abstract	Sheng Jing Decoction (SJD), as a traditional Chinese medicine prescription, is mainly be used to treat male infertility. However, the pharmacological functions and molecular mechanisms of SJD are poorly understood. In this study, we investigated the functions of SJD on spermatogenesis and sperm motility and explored the potential mechanisms involved. Here, we demonstrated that high, medium, and low doses of SJD are effective in restoring the impairments of the whole body and testicular tissue by cyclophosphamide inducing and to rescue the damage of testicular tissue cells including Sertoli cells and germ cells. SJD can partly restore the decrease in sperm concentration, sperm vitality, sperm motility, and normal sperm morphology rate in oligozoospermic mouse models. Ki67 staining analyses confirm SJD can promote testicular tissue cell proliferation. Real-time RT-PCR analyses also reveal that SJD can upregulate the expression of proliferation-associated gene Lin28a and differentiation-associated genes Kit, Sohlh2, and Stra8. SJD can also reduce the impairment of mitochondrial membrane potential (MMP) and sperm plasma membrane integrity by cyclophosphamide inducing. Our results reveal that SJD is effective in improving both sperm quantity and quality by increasing the sperm concentration, sperm vitality, sperm motility, and normal sperm morphology rate. SJD can promote spermatogenesis by upregulating the expression of the proliferation-associated gene Lin28a and the differentiation-associated genes (Kit, Sohlh2, and Stra8). SJD can sustain MMP and sperm plasma membrane integrity to increase sperm motility.
Keywords	Other systems of medicine ; RZ201-999
Subject code	572
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Effects of temperature and grazing on soil organic carbon storage in grasslands along the Eurasian steppe eastern transect.

Yanyun Zhao / Yong Ding / Xiangyang Hou / Frank Yonghong Li / Wenjun Han / Xiangjun Yun

PLoS ONE, Vol 12, Iss 10, p e

2017 Volume 0186980

Abstract: Soil represents the largest terrestrial organic carbon pool. To address global climate change, it is essential to explore the soil organic carbon storage patterns and their controlling factors. We investigated the soil organic carbon density (SOCD) in 48 ...

Abstract	Soil represents the largest terrestrial organic carbon pool. To address global climate change, it is essential to explore the soil organic carbon storage patterns and their controlling factors. We investigated the soil organic carbon density (SOCD) in 48 grassland sites along the Eurasian steppe eastern transect (ESET) region, which covers the Inner Mongolia grassland subregion and Mongolia grasslands subregion. Specifically, we analyzed the SOCD in the top 30 cm soil layer and its relationships with climatic variables, soil texture, grazing intensity and community biomass productivity. The results showed that the average SOCD of the ESET was 4.74 kg/m2, and the SOCD of the Inner Mongolia grassland subregion (4.11 kg/m2) was significantly lower than that of the Mongolia grassland subregion (5.79 kg/m2). Significant negative relationships were found between the SOCD and the mean annual temperature (MAT), mean annual precipitation (MAP) and grazing intensity in the ESET region. The MAT and grazing intensity were identified as the major factors influencing the SOCD in the ESET region; the MAP and MAT were the major factors influencing the SOCD in the Inner Mongolia grassland subregion; and the MAT and soil pH were the major factors influencing the SOCD in the Mongolia grassland subregion.
Keywords	Medicine ; R ; Science ; Q
Subject code	550
Language	English
Publishing date	2017-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Evaluating Algeria’s social and economic development using a series of night-time light images between 1992 to 2012

Li, Xi / Bouarouri Faouzi / Chuanqing Wu / Huazhong Jin / Lixian Zhao / Prosper Washaya / Wenjun Han / Xubing Zhang

International journal of remote sensing. 2018 Dec. 2, v. 39, no. 23

2018

Abstract: After social and economic problems, Algeria regained its night-time light (NL) brightness as this analysis of space-borne images shows. We evaluate the advancement of artificial light sources and the socioeconomic development between 1992 to 2012 for all ...

Abstract	After social and economic problems, Algeria regained its night-time light (NL) brightness as this analysis of space-borne images shows. We evaluate the advancement of artificial light sources and the socioeconomic development between 1992 to 2012 for all 48 provinces. Image calibration improved the consistency and comparability of the DMSP-OLS data. Light detected from gas flaring has been separated to focus on light from human settlements. We then estimated the relationship between night-time light and selected socioeconomic parameters (SEP). Night-time light growth (NLG) and night-time light annual growth (NLAG) indices are calculated at the national, regional and provincial level. Considering the Oil price crash and the Algerian Civil Concord, we take a detailed look at these historic events in Algeria. Our main findings are: (A) The total night-time light (TNL) for human settlements grew nationwide by 128%, (B) night-time light data correlates with socioeconomic parameters such as population, and electric power consumption, (C) the oil price crash resulted in slower night-time light growth, while the Algerian Civil Concord and the end of the crises led to increased TNL, (D) because of government investment, the High Plateaus are the fastest growing region since the end of the crises, (E) space-borne night-time light data can consistently fill the information gap when data from official sources are not available. Government and policy-making bodies may benefit from the presented findings allowing them to oversee and address provincial inequalities and economic development.
Keywords	electric power ; energy use and consumption ; human settlements ; oils ; prices ; remote sensing ; socioeconomic development ; Algeria
Language	English
Dates of publication	2018-1202
Size	p. 9228-9248.
Publishing place	Taylor & Francis
Document type	Article
ZDB-ID	1497529-4
ISSN	1366-5901 ; 0143-1161
ISSN (online)	1366-5901
ISSN	0143-1161
DOI	10.1080/01431161.2018.1510560
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Null alleles in microsatellite markers

Yafeng Wen / Kentaro Uchiyama / Wenjun Han / Saneyoshi Ueno / Weidong Xie / Gangbiao Xu / Yoshihiko Tsumura

Biodiversity Science, Vol 21, Iss 1, Pp 117-

2013 Volume 126

Abstract: Microsatellite markers are widely used in genetic analysis, but the common occurrence of null alleles, is an unfortunate drawback, and one which has not been paid enough attention. In this review, we confirmthe concept of null alleles and their ... ...

Abstract	Microsatellite markers are widely used in genetic analysis, but the common occurrence of null alleles, is an unfortunate drawback, and one which has not been paid enough attention. In this review, we confirmthe concept of null alleles and their characteristics, detail methods for estimating the frequency of null alleles and discuss potential causes. We also consider the effect of null alleles on genetic studies, such as measurement of population genetic diversity, parentage analysis and assignment tests. The review has a certain reference value for future studies. One main cause of microsatellite null alleles is poor primer annealing due to nucleotide sequence divergence (point mutations or indels) in one or both flanking primers. Microsatellite null alleles are not a natural characteristic of a specific gene, and are essentially different from isozyme null alleles. Although microsatellite null alleles have the characteristics of universality, complexity and invisibility, we can test and estimate their frequency through multiplex approaches, using Hardy-Weinbergequilibrium tests, parent-offspring genotype analysis, and new primer design. Null alleles have significant effects on the results of genetic analysis, potentially decreasing population genetic diversity and increasing genetic differentiation among populations. Moreover, null alleles may decrease the probability of parentage exclusion, even leading to errors or confusion in parentage analysis. Null alleles should be paid more attention and demand caution in future studies. Through a variety of methods, such as locus selection, null alleledata adjustment, and the design of new primers, we can escape the adverse effects of null alleles and achieve greater accuracy in genetic analysis.
Keywords	null alleles ; microsatellite markers ; allele frequency ; Hardy-Weinberg equilibrium ; Biology (General) ; QH301-705.5 ; Science ; Q ; DOAJ:Biology ; DOAJ:Biology and Life Sciences
Subject code	590
Language	Chinese
Publishing date	2013-01-01T00:00:00Z
Publisher	Science Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Analgesia effect of a fixed nitrous oxide/oxygen mixture on burn dressing pain

Yuxiang Li / Lu Tang / Jianqiang Yu / Xiuying Dai / Wanfang Zhou / Wannian Zhang / Xiaoyan Hu / Shichu Xiao / Wen Ni / Xiuqiang Ma / Yinsheng Wu / Ming Yao / Guoxia Mu / Guangyi Wang / Wenjun Han / Zhaofan Xia / Hongtai Tang / Jijun Zhao

Trials, Vol 13, Iss 1, p

study protocol for a randomized controlled trial

2012 Volume 67

Abstract: Abstract Background Procedural burn pain is the most intense acute pain and most likely type of burn injury pain to be undertreated due to the physician’s fear of the adverse effect of analgesia and lack of anesthetist present. At our institution, in ... ...

Abstract	Abstract Background Procedural burn pain is the most intense acute pain and most likely type of burn injury pain to be undertreated due to the physician’s fear of the adverse effect of analgesia and lack of anesthetist present. At our institution, in most of the cases, local burn detersion and debridement were performed at the ward level without any analgesics. This article describes a study designed to test the analgesia effect of a fixed nitrous oxide/oxygen mixture on burn dressing pain. Methods/design The experiment was carried out in three centers. The patients were given a number from 1 to 240. A randomization list was produced by a statistician according to our preliminary study. Due to the severity of the pain suffered, ethically it was decided to help as many as possible, so patients given the letters A, B or C were treated using a canister with the appropriate letter containing preprepared nitrous oxide/oxygen mixture (NOOM). Those with D were given oxygen only, from an identical-looking canister labeled D. Neither patients, nor doctors, nor nurses, nor data collector knew what was in each canister, thus they were all blind. The nursing officer who implemented the intervention handed the doctors envelopes containing the patients’ name and allocation of A, B, C or D. Thus, patients receiving NOOM or oxygen were in the ratio 3:1. Parameters, including pain severity, blood pressure, heart rate, digital oxygen saturation and the Chinese version of the burn specific pain anxiety scale (C-BSPAS), were taken before, during and after dressing for each group. A video and audio record was taken individually for later communication coding and outcome analysis. Rescue analgesic was recorded. Discussion Based on the findings from our previous qualitative study that physician’s reluctance to order narcotic analgesia is due to its adverse effect and from our pilot experiment, this study aims to test the hypothesis that a fixed nitrous oxide/oxygen mixture will promote better burn dressing pain alleviation and ...
Keywords	Analgesia ; Burn procedural pain ; Nitrous oxide ; Medicine (General) ; R5-920
Subject code	150
Language	English
Publishing date	2012-05-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Analgesia effect of a fixed nitrous oxide/oxygen mixture on burn dressing pain: study protocol for a randomized controlled trial.

Yuxiang, Li / Lu, Tang / Jianqiang, Yu / Xiuying, Dai / Wanfang, Zhou / Wannian, Zhang / Xiaoyan, Hu / Shichu, Xiao / Wen, Ni / Xiuqiang, Ma / Yinsheng, Wu / Ming, Yao / Guoxia, Mu / Guangyi, Wang / Wenjun, Han / Zhaofan, Xia / Hongtai, Tang / Jijun, Zhao

Trials

2012 Volume 13, Page(s) 67

Abstract: Background: Procedural burn pain is the most intense acute pain and most likely type of burn injury pain to be undertreated due to the physician's fear of the adverse effect of analgesia and lack of anesthetist present. At our institution, in most of ... ...

Abstract	Background: Procedural burn pain is the most intense acute pain and most likely type of burn injury pain to be undertreated due to the physician's fear of the adverse effect of analgesia and lack of anesthetist present. At our institution, in most of the cases, local burn detersion and debridement were performed at the ward level without any analgesics. This article describes a study designed to test the analgesia effect of a fixed nitrous oxide/oxygen mixture on burn dressing pain. Methods/design: The experiment was carried out in three centers. The patients were given a number from 1 to 240. A randomization list was produced by a statistician according to our preliminary study. Due to the severity of the pain suffered, ethically it was decided to help as many as possible, so patients given the letters A, B or C were treated using a canister with the appropriate letter containing preprepared nitrous oxide/oxygen mixture (NOOM). Those with D were given oxygen only, from an identical-looking canister labeled D. Neither patients, nor doctors, nor nurses, nor data collector knew what was in each canister, thus they were all blind. The nursing officer who implemented the intervention handed the doctors envelopes containing the patients' name and allocation of A, B, C or D. Thus, patients receiving NOOM or oxygen were in the ratio 3:1. Parameters, including pain severity, blood pressure, heart rate, digital oxygen saturation and the Chinese version of the burn specific pain anxiety scale (C-BSPAS), were taken before, during and after dressing for each group. A video and audio record was taken individually for later communication coding and outcome analysis. Rescue analgesic was recorded. Discussion: Based on the findings from our previous qualitative study that physician's reluctance to order narcotic analgesia is due to its adverse effect and from our pilot experiment, this study aims to test the hypothesis that a fixed nitrous oxide/oxygen mixture will promote better burn dressing pain alleviation and outcomes. Analyses will focus on the effects of the experimental intervention on pain severity during dressing (primary outcomes); physiological parameters, C-BSPAS and acceptance of both health care professionals and patients (secondary outcomes). If this model of analgesia for burn pain management implemented by nurses proves successful, it could potentially be implemented widely in hospital and prehospital settings and improve patients' satisfaction and quality of life. Trial registration: (Clinical Trials Identifier: CHICTR-TRC11001690).
MeSH term(s)	Administration, Inhalation ; Analgesics/administration & dosage ; Bandages/adverse effects ; Burns/complications ; Burns/psychology ; Burns/therapy ; China ; Double-Blind Method ; Humans ; Nitrous Oxide/administration & dosage ; Oxygen/administration & dosage ; Pain/diagnosis ; Pain/etiology ; Pain/prevention & control ; Pain/psychology ; Pain Management/methods ; Pain Measurement ; Research Design ; Severity of Illness Index ; Time Factors ; Treatment Outcome ; Video Recording
Chemical Substances	Analgesics ; Nitrous Oxide (K50XQU1029) ; Oxygen (S88TT14065)
Language	English
Publishing date	2012-05-24
Publishing country	England
Document type	Journal Article ; Multicenter Study ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	2040523-6
ISSN	1745-6215 ; 1468-6694 ; 1468-6708
ISSN (online)	1745-6215 ; 1468-6694
ISSN	1468-6708
DOI	10.1186/1745-6215-13-67
Database	MEDical Literature Analysis and Retrieval System OnLINE

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