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Article ; Online: Fabrication of bioactive glass/phosphorylated chitosan composite scaffold and its effects on MC3T3-E1 cells.

Wenxiu, Liu / Guojiang, Han / Liying, Qin / Wenli, Dong / Baoqin, Han / Liming, Jin / Yan, Yang

2024 Volume 19, Issue 2

Abstract: This study aimed to synthesize bioactive glass (BG) and phosphorylated chitosan (PCS), and fabricate a BG/PCS composite scaffold. The physical properties (mechanical strength, swelling degree, and degradation rate) of the BG/PCS scaffold were tested. ... ...

Abstract	This study aimed to synthesize bioactive glass (BG) and phosphorylated chitosan (PCS), and fabricate a BG/PCS composite scaffold. The physical properties (mechanical strength, swelling degree, and degradation rate) of the BG/PCS scaffold were tested. The
MeSH term(s)	Chitosan/chemistry ; Tissue Scaffolds/chemistry ; Tissue Engineering/methods ; Biocompatible Materials ; Glass/chemistry
Chemical Substances	Chitosan (9012-76-4) ; Biocompatible Materials
Language	English
Publishing date	2024-01-16
Publishing country	England
Document type	Journal Article
ZDB-ID	2265222-X
ISSN	1748-605X ; 1748-6041
ISSN (online)	1748-605X
ISSN	1748-6041
DOI	10.1088/1748-605X/ad1bb0
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Article ; Online: Insight into extracellular vesicles in vascular diseases

Wenxiu Liu / Meiqi Jin / Qiuyan Chen / Qiaoyu Li / Xiaoyan Xing / Yun Luo / Xiaobo Sun

Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-

intercellular communication role and clinical application potential

2023 Volume 34

Abstract: Abstract Background Cells have been increasingly known to release extracellular vesicles (EVs) to the extracellular environment under physiological and pathological conditions. A plethora of studies have revealed that EVs contain cell-derived ... ...

Abstract	Abstract Background Cells have been increasingly known to release extracellular vesicles (EVs) to the extracellular environment under physiological and pathological conditions. A plethora of studies have revealed that EVs contain cell-derived biomolecules and are found in circulation, thereby implicating them in molecular trafficking between cells. Furthermore, EVs have an effect on physiological function and disease development and serve as disease biomarkers. Main body Given the close association between EV circulation and vascular disease, this review aims to provide a brief introduction to EVs, with a specific focus on the EV cargoes participating in pathological mechanisms, diagnosis, engineering, and clinical potential, to highlight the emerging evidence suggesting promising targets in vascular diseases. Despite the expansion of research in this field, some noticeable limitations remain for clinical translational research. Conclusion This review makes a novel contribution to a summary of recent advances and a perspective on the future of EVs in vascular diseases. Video Abstract
Keywords	Extracellular vesicles ; Vascular disease ; Intercellular communication ; Clinical application ; Targets ; Biomarkers ; Medicine ; R ; Cytology ; QH573-671
Subject code	610
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Occurrence, distribution, and ecological risk of psychoactive substances in typical lakes and rivers in Qinghai-Tibet Plateau

Wenxiu Liu / Heng Zhang / Yang Liu / Xu Li / Haijian Lu / Changsheng Guo / Jian Xu

Ecotoxicology and Environmental Safety, Vol 242, Iss , Pp 113928- (2022)

2022

Abstract: The occurrence, distribution, and ecological risks of psychoactive substances (PSs) in Qinghai-Tibet Plateau (QTP) was investigated in this study. The surface water samples were collected in July in 2020 from five major water bodies, and 9 PSs were ... ...

Abstract	The occurrence, distribution, and ecological risks of psychoactive substances (PSs) in Qinghai-Tibet Plateau (QTP) was investigated in this study. The surface water samples were collected in July in 2020 from five major water bodies, and 9 PSs were determined by liquid chromatography-mass spectrometry. The mean concentrations of the total PSs were 2.19–96.86 ng/L in lakes and 4.56–34.47 ng/L in rivers. Amphetamine (AMP) was the predominant contaminant both in lakes and rivers with a mean concentration of 12.21 ± 22.76 ng/L and 9.83 ± 6.14 ng/L, respectively. The compositions of PSs in lakes and rivers were significantly different. AMP, methadone (MTD), 3,4-methylenedioxyamphetamine (MDA), and ketamine (KET) were the most detected contaminants in lakes, while in rivers AMP, MDA, heroin (HER), and methamphetamine (METH) were the most detected ones. Concentrations of AMP and MTD, the two predominant drugs, varied spatially, with the decreasing concentration of AMP in the order of Huangshui River > Yamzhog Yumco Lake > Qinghai Lake > Lhasa River > Namco Lake, and of MTD in the order of Qinghai Lake > Namco Lake > Huangshui River > Yamzhog Yumco Lake. The risk quotients (RQs) of PSs ranged from 4.44 × 10−6 to 4.32 × 10−2, indicating a low risk of PSs in the aquatic ecosystem in QTP. Compared with other research in the world, the contamination of psychoactive substances in the Qinghai-Tibet Plateau was at relatively low levels with low ecological risks.
Keywords	Psychoactive substances ; Qinghai-Tibet Plateau ; Amphetamine ; Methadone ; Risk assessment ; Environmental pollution ; TD172-193.5 ; Environmental sciences ; GE1-350
Subject code	333
Language	English
Publishing date	2022-09-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A review on perfluoroalkyl acids studies

Wenxiu Liu / Jingyi Wu / Wei He / Fuliu Xu

Ecosystem Health and Sustainability, Vol 5, Iss 1, Pp 1-

Environmental behaviors, toxic effects, and ecological and health risks

2019 Volume 19

Abstract: Perfluoroalkyl acids (PFAAs) are emerging persistent organic pollutants that are globally distributed in the environment. In the present review, the occurrence of PFAAs and their behavior in aquatic ecosystem were summarized, and the health and ... ...

Abstract	Perfluoroalkyl acids (PFAAs) are emerging persistent organic pollutants that are globally distributed in the environment. In the present review, the occurrence of PFAAs and their behavior in aquatic ecosystem were summarized, and the health and ecological risk assessment and the multimedia fate simulation were investigated. PFAAs are most likely to exist in the aqueous phase, and PFAAs in atmosphere are also able to enter water bodies through diffusion and wet and dry deposition and eventually become widely distributed in various environmental media. The air-solid partition is considered to be one of the major factors in the long-distance transportation of the pollutants. The pKa values and organic carbon fraction of the sediment could influence the partition of PFAAs between water and sediment. Otherwise, PFAAs have teratogenic, mutagenic and other toxic effects and they could be accumulated by biota, and magnified through trophic level. The ecological and health risks of PFOA and PFOS were assessment. In order to explore the partition mechanism and reduce the uncertainty of the simulation of the transport, transformation and fate, the experimental methods on physicochemical properties of PFAAs should be developed. Moreover, further studies on toxicities of PFAAs are necessary for health and ecological risk assessment.
Keywords	perfluoroalkyl acids (pfaas) ; distribution ; environmental behaviors ; risk assessment ; multimedia fate ; Ecology ; QH540-549.5
Subject code	910
Language	English
Publishing date	2019-01-01T00:00:00Z
Publisher	Taylor & Francis Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Low-Dimensional Semiconductors in Artificial Photosynthesis

Hui Wang / Wenxiu Liu / Sen Jin / Xiaodong Zhang / Yi Xie

ACS Central Science, Vol 6, Iss 7, Pp 1058-

An Outlook for the Interactions between Particles/Quasiparticles

2020 Volume 1069

Keywords	Chemistry ; QD1-999
Language	English
Publishing date	2020-06-01T00:00:00Z
Publisher	American Chemical Society
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Driving Factors of Land Surface Temperature in Urban Agglomerations

Wenxiu Liu / Qingyan Meng / Mona Allam / Linlin Zhang / Die Hu / Massimo Menenti

Remote Sensing, Vol 13, Iss 2858, p

A Case Study in the Pearl River Delta, China

2021 Volume 2858

Abstract: Land surface temperature (LST) in urban agglomerations plays an important role for policymakers in urban planning. The Pearl River Delta (PRD) is one of the regions with the highest urban densities in the world. This study aims to explore the spatial ... ...

Abstract	Land surface temperature (LST) in urban agglomerations plays an important role for policymakers in urban planning. The Pearl River Delta (PRD) is one of the regions with the highest urban densities in the world. This study aims to explore the spatial patterns and the dominant drivers of LST in the PRD. MODIS LST (MYD11A2) data from 2005 and 2015 were used in this study. First, spatial analysis methods were applied in order to determine the spatial patterns of LST and to identity the hotspot areas (HSAs). Second, the hotspot ratio index (HRI), as a metric of thermal heterogeneity, was developed in order to identify the features of thermal environment across the nine cities in the PRD. Finally, the geo-detector (GD) metric was employed to explore the dominant drivers of LST, which included elevation, land use/land cover (LUCC), the normalized difference vegetation index (NDVI), impervious surface distribution density (ISDD), gross domestic product (GDP), population density (POP), and nighttime light index (NLI). The GD metric has the advantages of detecting the dominant drivers without assuming linear relationships and measuring the combined effects of the drivers. The results of Moran’s Index showed that the daytime and nighttime LST were close to the cluster pattern. Therefore, this process led to the identification of HSAs. The HSAs were concentrated in the central PRD and were distributed around the Pearl River estuary. The results of the HRI indicated that the spatial distribution of the HSAs was highly heterogeneous among the cities for both daytime and nighttime. The highest HRI values were recorded in the cities of Dongguan and Shenzhen during the daytime. The HRI values in the cities of Zhaoqing, Jiangmen, and Huizhou were relatively lower in both daytime and nighttime. The dominant drivers of LST varied from city to city. The influence of land cover and socio-economic factors on daytime LST was higher in the highly urbanized cities than in the cities with low urbanization rates. For the cities of ...
Keywords	land surface temperature ; spatial analysis ; urban agglomeration ; driving factors ; geo-detector metric ; Science ; Q
Subject code	910
Language	English
Publishing date	2021-07-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Relationships between Land Surface Temperatures and Neighboring Environment in Highly Urbanized Areas

Qingyan Meng / Wenxiu Liu / Linlin Zhang / Mona Allam / Yaxin Bi / Xinli Hu / Jianfeng Gao / Die Hu / Tamás Jancsó

Remote Sensing, Vol 14, Iss 4340, p

Seasonal and Scale Effects Analyses of Beijing, China

2022 Volume 4340

Abstract: Urban environments have a strong influence on the land surface temperature (LST) in urban areas. Understanding the relationship between LST and urban environmental factors can help develop effective strategies to reduce high LSTs in urban areas, which is ...

Abstract	Urban environments have a strong influence on the land surface temperature (LST) in urban areas. Understanding the relationship between LST and urban environmental factors can help develop effective strategies to reduce high LSTs in urban areas, which is critical for mitigating the urban heat island effect. Previous studies have focused on the correlation between LST and the environmental factors that drive its formation, without considering the influences of the neighboring environment and the vertical expansion of highly urbanized areas. Notably, the correlation between LST and its neighboring environment in different seasons remains unclear. In this study, we selected central Beijing in China as our study area and employed the moving window method to characterize the environmental factors of the neighboring environment of the central LST cell. We explored eight environmental factors from three layers: normalized difference vegetation index (NDVI), normalized difference built-up index (NDBI), modified normalized difference water index (MNDWI), building density (BD), building height (BH), building volume (BV), sky view factor (SVF), and road density (RD). The Pearson correlation and extreme gradient boosting (XGB) regression methods were applied to measure the correlation between LST and the different factors in moving windows of different sizes. The results indicated that the correlation between NDVI, MNDWI, and LST was considerably different in the winter and other seasons. However, NDBI was positively correlated with LST in all seasons, although the correlation was strongest/weakest in summer/winter. Among building-related factors, BD and BH were more strongly correlated with LST, and the positive/negative correlation between BD/BH and LST was stronger in summer/winter. The correlation between LST and its neighboring environment varied with increasing window size, and this variation differs significantly between winter and other seasons. In spring, summer, and autumn, the strength of the correlation between ...
Keywords	land surface temperature ; neighboring environment ; seasonal effect ; scale effect ; optimal spatial scale ; urban heat island ; Science ; Q
Subject code	333
Language	English
Publishing date	2022-09-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Identification of Crucial lncRNAs, miRNAs, mRNAs, and Potential Therapeutic Compounds for Polycystic Ovary Syndrome by Bioinformatics Analysis

Zhi Zeng / Xia Lin / Tingting Xia / Wenxiu Liu / Xiaohui Tian / Manchao Li

BioMed Research International, Vol

2020 Volume 2020

Abstract: Background. This study was aimed at mining crucial long noncoding RNAs (lncRNAs), microRNAs (miRNAs), and messenger RNAs (mRNAs) for the development of polycystic ovary syndrome (PCOS) based on the coexpression and the competitive endogenous RNA (ceRNA) ... ...

Abstract	Background. This study was aimed at mining crucial long noncoding RNAs (lncRNAs), microRNAs (miRNAs), and messenger RNAs (mRNAs) for the development of polycystic ovary syndrome (PCOS) based on the coexpression and the competitive endogenous RNA (ceRNA) theories and investigating the underlying therapeutic drugs that may function by reversing the expression of lncRNAs, miRNAs, and mRNAs. Methods. RNA (GSE106724, GSE114419, GSE137684, and GSE138518) or miRNA (GSE84376 and GSE138572) expression profile datasets of PCOS patients were downloaded from the Gene Expression Omnibus database. The weighted gene coexpression network analysis (WGCNA) using four RNA datasets was conducted to construct the lncRNA-mRNA coexpression networks, while the common differentially expressed miRNAs in two miRNA datasets and module RNAs were used to establish the ceRNA network. A protein-protein interaction (PPI) network was created to explore the potential interactions between genes. Gene Ontology and KEGG pathway enrichment analyses were performed to explore the functions of genes in networks. Connectivity Map (CMap) and Comparative Toxicogenomics Database (CTD) analyses were performed to identify potential therapeutic agents for PCOS. Results. Three modules (black, magenta, and yellow) were identified to be PCOS-related after WGCNA analysis, in which KLF3-AS1-PLCG2, MAPKAPK5-AS1-MAP3K14, and WWC2-AS2-TXNIP were important coexpression relationship pairs. WWC2-AS2-hsa-miR-382-PLCG2 was a crucial ceRNA loop in the ceRNA network. The PPI network showed that MAP3K14 and TXNIP could interact with hub genes PLK1 (degree=21) and TLR1 (degree=18), respectively. These genes were enriched into mitosis (PLK1), immune response (PLCG2 and TLR1), and cell cycle (TXNIP and PLK1) biological processes. Ten small molecule drugs (especially quercetin) were considered to be therapeutical for PCOS. Conclusion. Our study may provide a novel insight into the mechanisms and therapy for PCOS.
Keywords	Medicine ; R
Subject code	572
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Modification to L-H Kinetics Model and Its Application in the Investigation on Photodegradation of Gaseous Benzene by Nitrogen-Doped TiO2

Peng Sun / Jun Zhang / Wenxiu Liu / Qi Wang / Wenbin Cao

Catalysts, Vol 8, Iss 8, p

2018 Volume 326

Abstract: In this paper, the Langmuir-Hinshelwood (L-H) model has been used to investigate the kinetics of photodegradation of gaseous benzene by nitrogen-doped TiO2 (N-TiO2) at 25 °C under visible light irradiation. Experimental results show that the ... ...

Abstract	In this paper, the Langmuir-Hinshelwood (L-H) model has been used to investigate the kinetics of photodegradation of gaseous benzene by nitrogen-doped TiO2 (N-TiO2) at 25 °C under visible light irradiation. Experimental results show that the photoreaction coefficient kpm increased from 3.992 × 10−6 mol·kg−1·s−1 to 11.55 × 10−6 mol·kg−1·s−1 along with increasing illumination intensity. However, the adsorption equilibrium constant KL decreased from 1139 to 597 m3·mol−1 when the illumination intensity increased from 36.7 × 104 lx to 75.1 × 104 lx, whereas it was 2761 m3·mol−1 in the absence of light. This is contrary to the fact that KL should be a constant if the temperature was fixed. This phenomenon can be attributed to the breaking of the adsorption-desorption equilibrium by photocatalytically decomposition. To compensate for the disequilibrium of the adsorption-desorption process, photoreaction coefficient kpm was introduced to the expression of KL and the compensation form was denoted as Km. KL is an indicator of the adsorption capacity of TiO2 while Km is only an indicator of the coverage ratio of TiO2 surface. The modified L-H model has been experimentally verified so it is expected to be used to predict the kinetics of the photocatalytic degradation of gaseous benzene.
Keywords	modified L-H model ; N-TiO2 ; photocatalytic degradation ; benzene ; Chemical technology ; TP1-1185 ; Chemistry ; QD1-999
Subject code	660
Language	English
Publishing date	2018-08-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Synthesis of mesoporous core-shell TiO2 microstructures with coexposed {001}/{101} facets: enhanced intrinsic photocatalytic performance

Wang, Liang / Yingjuan Xie / Wenxiu Liu / Qi Wang / Wenbin Cao

Environmental science and pollution research international. 2018 Nov., v. 25, no. 31

2018

Abstract: TiO₂ microstructures were synthesized via a facile one-step route for enhanced intrinsic photocatalytic performance. The prepared TiO₂ microstructures are featured by both mesoporous core-shell structures and coexposed {001}/{101} facets. Their intrinsic ...

Abstract	TiO₂ microstructures were synthesized via a facile one-step route for enhanced intrinsic photocatalytic performance. The prepared TiO₂ microstructures are featured by both mesoporous core-shell structures and coexposed {001}/{101} facets. Their intrinsic photocatalytic performance were remarkably enhanced due to their high specific surface area, coexposed {001}/{101} facets, and promoted separation of photogenerated carriers. Furthermore, the origin and detailed mechanism for diethylenetriamine (DETA) that served as a high efficient stabilizer of TiO₂ {001} facet have been theoretically investigated. Finally, a new DETA-modified Ostwald ripening mechanism was originally proposed when studying the growth mechanism of the mesoporous core-shell TiO₂ spherical microstructures with coexposed {001}/{101} facets.
Keywords	Ostwald ripening ; microstructure ; photocatalysis ; porous media ; stabilizers ; surface area ; titanium dioxide
Language	English
Dates of publication	2018-11
Size	p. 31250-31261.
Publishing place	Springer Berlin Heidelberg
Document type	Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-018-3113-9
Database	NAL-Catalogue (AGRICOLA)

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