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  1. Article ; Online: Adolescent Opioid Misuse Attributable to Adverse Childhood Experiences.

    Swedo, Elizabeth A / Sumner, Steven A / de Fijter, Sietske / Werhan, Luke / Norris, Kirkland / Beauregard, Jennifer L / Montgomery, Martha P / Rose, Erica B / Hillis, Susan D / Massetti, Greta M

    The Journal of pediatrics

    2020  Volume 224, Page(s) 102–109.e3

    Abstract: Objectives: To estimate the proportion of opioid misuse attributable to adverse childhood experiences (ACEs) among adolescents.: Study design: A cross-sectional survey was administered to 10 546 seventh-to twelfth-grade students in northeastern Ohio ... ...

    Abstract Objectives: To estimate the proportion of opioid misuse attributable to adverse childhood experiences (ACEs) among adolescents.
    Study design: A cross-sectional survey was administered to 10 546 seventh-to twelfth-grade students in northeastern Ohio in Spring 2018. Study measures included self-reported lifetime exposure to 10 ACEs and past 30-day use of nonmedical prescription opioid or heroin. Using generalized estimating equations, we evaluated associations between recent opioid misuse, individual ACEs, and cumulative number of ACEs. We calculated population attributable fractions to determine the proportion of adolescents' recent opioid misuse attributable to ACEs.
    Results: Nearly 1 in 50 adolescents reported opioid misuse within 30 days (1.9%); approximately 60% of youth experienced ≥1 ACE; 10.2% experienced ≥5 ACEs. Cumulative ACE exposure demonstrated a significant graded relationship with opioid misuse. Compared with youth with zero ACEs, youth with 1 ACE (aOR 1.9, 95% CI, 0.9-3.9), 2 ACEs (aOR, 3.8; 95% CI, 1.9-7.9), 3 ACEs (aOR, 3.7; 95% CI, 2.2-6.5), 4 ACEs (aOR, 5.8; 95% CI, 3.1-11.2), and ≥5 ACEs (aOR, 15.3; 95% CI, 8.8-26.6) had higher odds of recent opioid misuse. The population attributable fraction of recent opioid misuse associated with experiencing ≥1 ACE was 71.6% (95% CI, 59.8-83.5).
    Conclusions: There was a significant graded relationship between number of ACEs and recent opioid misuse among adolescents. More than 70% of recent adolescent opioid misuse in our study population was attributable to ACEs. Efforts to decrease opioid misuse could include programmatic, policy, and clinical practice interventions to prevent and mitigate the negative effects of ACEs.
    MeSH term(s) Adolescent ; Adverse Childhood Experiences/psychology ; Adverse Childhood Experiences/statistics & numerical data ; Causality ; Cohort Studies ; Cross-Sectional Studies ; Female ; Humans ; Male ; Ohio/epidemiology ; Opioid-Related Disorders/epidemiology ; Opioid-Related Disorders/psychology
    Language English
    Publishing date 2020-05-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2020.05.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Associations Between Social Media and Suicidal Behaviors During a Youth Suicide Cluster in Ohio.

    Swedo, Elizabeth A / Beauregard, Jennifer L / de Fijter, Sietske / Werhan, Luke / Norris, Kirkland / Montgomery, Martha P / Rose, Erica B / David-Ferdon, Corinne / Massetti, Greta M / Hillis, Susan D / Sumner, Steven A

    The Journal of adolescent health : official publication of the Society for Adolescent Medicine

    2020  Volume 68, Issue 2, Page(s) 308–316

    Abstract: Purpose: Youth suicide clusters may be exacerbated by suicide contagion-the spread of suicidal behaviors. Factors promoting suicide contagion are poorly understood, particularly in the advent of social media. Using cross-sectional data from an ongoing ... ...

    Abstract Purpose: Youth suicide clusters may be exacerbated by suicide contagion-the spread of suicidal behaviors. Factors promoting suicide contagion are poorly understood, particularly in the advent of social media. Using cross-sectional data from an ongoing youth suicide cluster in Ohio, this study examines associations between suicide cluster-related social media and suicidal behaviors.
    Methods: We surveyed 7th- to 12th-grade students in northeastern Ohio during a 2017-2018 suicide cluster to assess the prevalence of suicidal ideation (SI), suicide attempts (SAs), and associations with potential contagion-promoting factors such as suicide cluster-related social media, vigils, memorials, news articles, and watching the Netflix series 13 Reasons Why before or during the cluster. Generalized estimating equations examined associations between potential contagion-promoting factors and SI/SA, adjusting for nonmodifiable risk factors. Subgroup analyses examined whether associations between cluster-related factors and SI/SA during the cluster varied by previous history of SI/SA.
    Results: Among participating students, 9.0% (876/9,733) reported SI and 4.9% attempted suicide (481/9,733) during the suicide cluster. Among students who posted suicide cluster-related content to social media, 22.9% (267/1,167) reported SI and 15.0% (175/1,167) attempted suicide during the suicide cluster. Posting suicide cluster-related content was associated with both SI (adjusted odds ratio 1.7, 95% confidence interval 1.4-2.0) and SA during the cluster (adjusted odds ratio 1.7, 95% confidence interval 1.2-2.5). In subgroup analyses, seeing suicide cluster-related posts was uniquely associated with increased odds of SI and SA during the cluster among students with no previous history of SI/SA.
    Conclusions: Exposure to suicide cluster-related social media is associated with both SI and SA during a suicide cluster. Suicide interventions could benefit from efforts to mitigate potential negative effects of social media and promote prevention messages.
    MeSH term(s) Adolescent ; Cross-Sectional Studies ; Humans ; Ohio/epidemiology ; Risk Factors ; Social Media ; Suicidal Ideation ; Suicide, Attempted
    Language English
    Publishing date 2020-07-07
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 1063374-1
    ISSN 1879-1972 ; 1054-139X
    ISSN (online) 1879-1972
    ISSN 1054-139X
    DOI 10.1016/j.jadohealth.2020.05.049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2453: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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