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  1. Article ; Online: The rapidly shifting paradigm of surgical education.

    Wexner, Steve

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2019  Volume 21, Issue 10, Page(s) 1111

    MeSH term(s) Colorectal Surgery/education ; Humans ; Problem-Based Learning/trends ; Simulation Training/trends
    Language English
    Publishing date 2019-09-30
    Publishing country England
    Document type Editorial
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.14743
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5799: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: The long overdue inception of accreditation of centres for rectal cancer surgery in the United States.

    Wexner, Steve / Berho, Mariana

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2015  Volume 17, Issue 6, Page(s) 465–467

    MeSH term(s) Accreditation ; Cancer Care Facilities/standards ; Humans ; Rectal Neoplasms/surgery ; United States
    Language English
    Publishing date 2015-06
    Publishing country England
    Document type Editorial
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.12981
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5799: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Which technique to choose in the high-tech era of minimal-access rectal cancer surgery?

    Chand, Manish / Moran, Brendan / Wexner, Steve D

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2016  Volume 18, Issue 9, Page(s) 839–841

    MeSH term(s) Digestive System Surgical Procedures/methods ; Humans ; Laparoscopy ; Lymph Node Excision ; Mesentery/surgery ; Rectal Neoplasms/surgery ; Rectum/surgery ; Robotic Surgical Procedures ; Transanal Endoscopic Surgery
    Language English
    Publishing date 2016-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.13361
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5799: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Why say "statistically significant" rather than just "significant"? a plea to rid the medical literature of linguistic ambiguity.

    Fingerhut, Abe / Wexner, Steve / Behrns, Kevin / Arrezo, Alberto / Buhler, Leo / Francis, Nader / Keller, Deborah S / Knoefel, Wolfram / Salminen, Paulina / Swanstrom, Lee / Winter, Des

    Surgery

    2022  Volume 172, Issue 4, Page(s) 1039–1040

    Language English
    Publishing date 2022-09-12
    Publishing country United States
    Document type Editorial
    ZDB-ID 202467-6
    ISSN 1532-7361 ; 0039-6060
    ISSN (online) 1532-7361
    ISSN 0039-6060
    DOI 10.1016/j.surg.2022.08.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Characteristics of Early-Onset vs Late-Onset Colorectal Cancer: A Review.

    Zaborowski, Alexandra M / Abdile, Ahmed / Adamina, Michel / Aigner, Felix / d'Allens, Laura / Allmer, Caterina / Álvarez, Andrea / Anula, Rocio / Andric, Mihailo / Atallah, Sam / Bach, Simon / Bala, Miklosh / Barussaud, Marie / Bausys, Augustinas / Bebington, Brendan / Beggs, Andrew / Bellolio, Felipe / Bennett, Melissa-Rose / Berdinskikh, Anton /
    Bevan, Vicki / Biondo, Sebastiano / Bislenghi, Gabriele / Bludau, Marc / Boutall, Adam / Brouwer, Nelleke / Brown, Carl / Bruns, Christiane / Buchanan, Daniel D / Buchwald, Pamela / Burger, Jacobus W A / Burlov, Nikita / Campanelli, Michela / Capdepont, Maylis / Carvello, Michele / Chew, Hwee-Hoon / Christoforidis, Dimitri / Clark, David / Climent, Marta / Cologne, Kyle G / Contreras, Tomas / Croner, Roland / Daniels, Ian R / Dapri, Giovanni / Davies, Justin / Delrio, Paolo / Denost, Quentin / Deutsch, Michael / Dias, Andre / D'Hoore, André / Drozdov, Evgeniy / Duek, Daniel / Dunlop, Malcolm / Dziki, Adam / Edmundson, Aleksandra / Efetov, Sergey / El-Hussuna, Alaa / Elliot, Brodie / Emile, Sameh / Espin, Eloy / Evans, Martyn / Faes, Seraina / Faiz, Omar / Fleming, Fergal / Foppa, Caterina / Fowler, George / Frasson, Matteo / Figueiredo, Nuno / Forgan, Tim / Frizelle, Frank / Gadaev, Shamil / Gellona, Jose / Glyn, Tamara / Gong, Jianping / Goran, Barisic / Greenwood, Emma / Guren, Marianne G / Guillon, Stephanie / Gutlic, Ida / Hahnloser, Dieter / Hampel, Heather / Hanly, Ann / Hasegawa, Hirotoshi / Iversen, Lene Hjerrild / Hill, Andrew / Hill, James / Hoch, Jiri / Hoffmeister, Michael / Hompes, Roel / Hurtado, Luis / Iaquinandi, Fabiano / Imbrasaite, Ugne / Islam, Rumana / Jafari, Mehrenah Dorna / Kanemitsu, Yukihide / Karachun, Aleksei / Karimuddin, Ahmer A / Keller, Deborah S / Kelly, Justin / Kennelly, Rory / Khrykov, Gleb / Kocian, Peter / Koh, Cherry / Kok, Neils / Knight, Katrina A / Knol, Joep / Kontovounisios, Christos / Korner, Hartwig / Krivokapic, Zoran / Kronberger, Irmgard / Kroon, Hidde Maarten / Kryzauskas, Marius / Kural, Said / Kusters, Miranda / Lakkis, Zaher / Lankov, Timur / Larson, Dave / Lázár, György / Lee, Kai-Yin / Lee, Suk Hwan / Lefèvre, Jérémie H / Lepisto, Anna / Lieu, Christopher / Loi, Lynette / Lynch, Craig / Maillou-Martinaud, Helene / Maroli, Annalisa / Martin, Sean / Martling, Anna / Matzel, Klaus E / Mayol, Julio / McDermott, Frank / Meurette, Guillaume / Millan, Monica / Mitteregger, Martin / Moiseenko, Andrei / Monson, John R T / Morarasu, Stefan / Moritani, Konosuke / Möslein, Gabriela / Munini, Martino / Nahas, Caio / Nahas, Sergio / Negoi, Ionut / Novikova, Anastasia / Ocares, Misael / Okabayashi, Koji / Olkina, Alexandra / Oñate-Ocaña, Luis / Otero, Jaime / Ozen, Cihan / Pace, Ugo / São Julião, Guilherme Pagin / Panaiotti, Lidiia / Panis, Yves / Papamichael, Demetris / Park, Jason / Patel, Swati / Patrón Uriburu, Juan Carlos / Pera, Miguel / Perez, Rodrigo O / Petrov, Alexei / Pfeffer, Frank / Phang, P Terry / Poskus, Tomas / Pringle, Heather / Proud, David / Raguz, Ivana / Rama, Nuno / Rasheed, Shahnawaz / Raval, Manoj J / Rega, Daniela / Reissfelder, Christoph / Reyes Meneses, Juan Carlos / Ris, Frederic / Riss, Stefan / Rodriguez-Zentner, Homero / Roxburgh, Campbell S / Saklani, Avanish / Salido, Andrea Jiménez / Sammour, Tarik / Saraste, Deborah / Schneider, Martin / Seishima, Ryo / Sekulic, Aleksandar / Seppala, Toni / Sheahan, Kieran / Shine, Rebecca / Shlomina, Alexandra / Sica, Guiseppe S / Singnomklao, Tongplaew / Siragusa, Leandro / Smart, Neil / Solis, Alejandro / Spinelli, Antonino / Staiger, Roxane D / Stamos, Michael J / Steele, Scott / Sunderland, Michael / Tan, Ker-Kan / Tanis, Pieter J / Tekkis, Paris / Teklay, Biniam / Tengku, Sabrina / Jiménez-Toscano, Marta / Tsarkov, Petr / Turina, Matthias / Ulrich, Alexis / Vailati, Bruna B / van Harten, Meike / Verhoef, Cornelis / Warrier, Satish / Wexner, Steve / de Wilt, Hans / Weinberg, Benjamin A / Wells, Cameron / Wolthuis, Albert / Xynos, Evangelos / You, Nancy / Zakharenko, Alexander / Zeballos, Justino / Winter, Des C

    JAMA surgery

    2021  Volume 156, Issue 9, Page(s) 865–874

    Abstract: Importance: The incidence of early-onset colorectal cancer (younger than 50 years) is rising globally, the reasons for which are unclear. It appears to represent a unique disease process with different clinical, pathological, and molecular ... ...

    Abstract Importance: The incidence of early-onset colorectal cancer (younger than 50 years) is rising globally, the reasons for which are unclear. It appears to represent a unique disease process with different clinical, pathological, and molecular characteristics compared with late-onset colorectal cancer. Data on oncological outcomes are limited, and sensitivity to conventional neoadjuvant and adjuvant therapy regimens appear to be unknown. The purpose of this review is to summarize the available literature on early-onset colorectal cancer.
    Observations: Within the next decade, it is estimated that 1 in 10 colon cancers and 1 in 4 rectal cancers will be diagnosed in adults younger than 50 years. Potential risk factors include a Westernized diet, obesity, antibiotic usage, and alterations in the gut microbiome. Although genetic predisposition plays a role, most cases are sporadic. The full spectrum of germline and somatic sequence variations implicated remains unknown. Younger patients typically present with descending colonic or rectal cancer, advanced disease stage, and unfavorable histopathological features. Despite being more likely to receive neoadjuvant and adjuvant therapy, patients with early-onset disease demonstrate comparable oncological outcomes with their older counterparts.
    Conclusions and relevance: The clinicopathological features, underlying molecular profiles, and drivers of early-onset colorectal cancer differ from those of late-onset disease. Standardized, age-specific preventive, screening, diagnostic, and therapeutic strategies are required to optimize outcomes.
    MeSH term(s) Adult ; Age of Onset ; Colorectal Neoplasms/epidemiology ; Colorectal Neoplasms/pathology ; Humans ; Incidence ; Middle Aged ; Risk Factors
    Language English
    Publishing date 2021-06-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2701841-6
    ISSN 2168-6262 ; 2168-6254
    ISSN (online) 2168-6262
    ISSN 2168-6254
    DOI 10.1001/jamasurg.2021.2380
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uk I Zs.72: Show issues Location:
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