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  1. Article: Clinical Evaluation of the Safety and Efficacy of Trifluridine/Tipiracil in the Treatment of Advanced Gastric/Gastroesophageal Junction Adenocarcinoma: Evidence to Date.

    Wheelden, Megan / Yee, Nelson S

    OncoTargets and therapy

    2020  Volume 13, Page(s) 7459–7465

    Abstract: Trifluridine/tipiracil or TAS-102 (Taiho Oncology, ... ...

    Abstract Trifluridine/tipiracil or TAS-102 (Taiho Oncology, Lonsurf
    Language English
    Publishing date 2020-07-30
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2495130-4
    ISSN 1178-6930
    ISSN 1178-6930
    DOI 10.2147/OTT.S216598
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Dobbs v Jackson

    Mittal, Kriti / Sheen, Melanie / Wheelden, Megan / Faramand, Rawan / Teplinsky, Eleonora / Joshi, Monika

    JCO oncology practice

    2023  Volume 19, Issue 4, Page(s) 157–159

    MeSH term(s) Humans ; Female ; Neoplasms/therapy ; Socioeconomic Factors ; Decision Making
    Language English
    Publishing date 2023-01-18
    Publishing country United States
    Document type Editorial
    ZDB-ID 3028198-2
    ISSN 2688-1535 ; 2688-1527
    ISSN (online) 2688-1535
    ISSN 2688-1527
    DOI 10.1200/OP.22.00610
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Durable Major Response With Pazopanib in Recurrent, Heavily Pretreated Metastatic Esthesioneuroblastoma Harboring a Fumarate Hydratase Mutation.

    Spengler, Marianne / Wheelden, Megan / Mackley, Heath B / Drabick, Joseph J

    JCO precision oncology

    2021  Volume 5

    MeSH term(s) Aged ; Esthesioneuroblastoma, Olfactory/drug therapy ; Esthesioneuroblastoma, Olfactory/genetics ; Esthesioneuroblastoma, Olfactory/secondary ; Female ; Fumarate Hydratase/genetics ; Humans ; Indazoles/therapeutic use ; Mutation ; Nasal Cavity ; Neoplasm Recurrence, Local/drug therapy ; Nose Neoplasms/drug therapy ; Nose Neoplasms/genetics ; Nose Neoplasms/pathology ; Pyrimidines/therapeutic use ; Remission Induction ; Retreatment ; Sulfonamides/therapeutic use ; Time Factors
    Chemical Substances Indazoles ; Pyrimidines ; Sulfonamides ; pazopanib (7RN5DR86CK) ; Fumarate Hydratase (EC 4.2.1.2)
    Language English
    Publishing date 2021-04-19
    Publishing country United States
    Document type Case Reports ; Journal Article
    ISSN 2473-4284
    ISSN (online) 2473-4284
    DOI 10.1200/PO.20.00486
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: A Novel Adverse Event Associated with Olaparib Therapy in a Patient with Metastatic Breast Cancer.

    Wheelden, Megan / Cream, Leah / Sivik, Jeffrey / Robson, Mark

    Case reports in oncological medicine

    2018  Volume 2018, Page(s) 9529821

    Abstract: Olaparib was first FDA approved for use in women with advanced ovarian cancer and germline BRCA mutations. Based on the results of subsequent research, the use of this drug has been expanded to patients with metastatic breast cancer with germline BRCA ... ...

    Abstract Olaparib was first FDA approved for use in women with advanced ovarian cancer and germline BRCA mutations. Based on the results of subsequent research, the use of this drug has been expanded to patients with metastatic breast cancer with germline BRCA mutation. With the use of a relatively new medication and a larger patient population eligible for therapy, monitoring for novel adverse events associated with therapy is important. This case represents a patient with metastatic breast cancer and germline BRCA2 mutation who developed erythema nodosum after initiation of therapy with olaparib capsules. Her characteristic rash appeared shortly after starting olaparib and recurred after restarting olaparib an additional two times. She was treated with short courses of prednisone therapy with or without holding olaparib with resolution of her rash. The patient was later restarted on olaparib capsules 200 mg twice daily, and she more recently has been maintained on olaparib tablets 300 mg twice daily. On both regimens, the patient experienced only attenuated episodes of erythema nodosum that have not required cessation of therapy or steroid therapy.
    Language English
    Publishing date 2018-06-27
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2629911-2
    ISSN 2090-6714 ; 2090-6706
    ISSN (online) 2090-6714
    ISSN 2090-6706
    DOI 10.1155/2018/9529821
    Database MEDical Literature Analysis and Retrieval System OnLINE

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