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  1. Article ; Online: Power increase of the power plant with single-circuit ORC plant with a wet medium, supplied with water in appropriate proportions from the Lower and Middle Triassic Reservoirs

    Wiśniewski Sławomir / Sołtysik Gabriela / Nowak Władysław

    E3S Web of Conferences, Vol 70, p

    2018  Volume 01020

    Abstract: This article presents an analysis of the efficiency of the ORC power plant with a wet circulating medium. The power plant is supplied from two heat sources, which are geothermal water streams obtained from the Lower Triassic and Middle Triassic ... ...

    Abstract This article presents an analysis of the efficiency of the ORC power plant with a wet circulating medium. The power plant is supplied from two heat sources, which are geothermal water streams obtained from the Lower Triassic and Middle Triassic Reservoirs. In the ORC system, it was assumed that one of these streams is directed to the superheater and the other to the evaporator. In the work, two variants of ORC power supply were considered. The first one, in which the maximum stream of water from the Middle Triassic Reservoir ṁg2 = 55 kg/s at a temperature of Tg12${\rm{T}}_{{\rm{g1}}}^2$ = 104°C powers the evaporator, while the water stream from the Lower Triassic Reservoir ṁg1 = 25 kg/s at a temperature of Tg11${\rm{T}}_{{\rm{g1}}}^1$$ = 128°C powers the superheater. In the second variant, the maximum water stream from the Lower Triassic Reservoir ṁg1 = 25 kg/s and a temperature of Tg11${\rm{T}}_{{\rm{g1}}}^1$$ = 128°C feeds the evaporator, while the water stream from the Middle Triassic Reservoir ṁg2 at a temperature of Tg12${\rm{T}}_{{\rm{g1}}}^2$ = 104°C supplies the superheater. In both variants, the geothermal water stream directed to the superheater is the size resulting from ORC plant operation and cannot exceed the maximum flow value for a given geothermal reservoir. The following working substances were taken into account in the analysis: cyclopropane, R143a, R32, propylene, R22, propane, R134a. The analysis carried out showed that in the ORC power plant with a two-source supply the maximum system power was obtained in the case of the first variant for the working medium R143a.
    Keywords Environmental sciences ; GE1-350
    Subject code 550
    Language English
    Publishing date 2018-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Multi-objective analysis of an influence of a brine mineralization on an optimal evaporation temperature in ORC power plant

    Jankowski Marcin / Wiśniewski Sławomir / Borsukiewicz Aleksandra

    E3S Web of Conferences, Vol 70, p

    2018  Volume 01005

    Abstract: The fact that Organic Rankine cycle system is very promising technology in terms of electricity production using low grade heat sources, necessitates constant research in order to determine the best cycle configuration or choose the most suitable working ...

    Abstract The fact that Organic Rankine cycle system is very promising technology in terms of electricity production using low grade heat sources, necessitates constant research in order to determine the best cycle configuration or choose the most suitable working fluid for certain application. In this paper, multi-objective optimization (MOO) approach has been applied in order to conduct an analysis that is to resolve if there is an influence of a mineralization of a geothermal water on an optimal evaporation temperature in ORC power plant with R1234yf as the working fluid.
    Keywords Environmental sciences ; GE1-350
    Language English
    Publishing date 2018-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Influence of the type of working fluid in the lower cycle and superheated steam parameters in the upper cycle on effectiveness of operation of binary power plant

    Stachel Aleksander A. / Wiśniewski Sławomir

    Archives of Thermodynamics, Vol 36, Iss 1, Pp 111-

    2015  Volume 123

    Abstract: In the paper presented have been the results of the analysis of effectiveness of operation of binary power plant consisting of combined two Clausius-Rankine cycles, namely the binary cycle with water as a working fluid in the upper cycle and organic ... ...

    Abstract In the paper presented have been the results of the analysis of effectiveness of operation of binary power plant consisting of combined two Clausius-Rankine cycles, namely the binary cycle with water as a working fluid in the upper cycle and organic substance as a working fluid in the lower cycle, as well as a single fluid component power plant operating also in line with the C-R cycle for superheated steam, with water as a working fluid. The influence of the parameters of superheated steam in the upper cycle has been assessed as well as the type of working fluid in the lower cycle. The results of calculations have been referred to the single-cycle classical steam power plant operating at the same parameters of superheated steam and the same mass flow rate of water circulating in both cycles. On the basis of accomplished analysis it has been shown that the binary power plant shows a greater power with respect to the reference power plant.
    Keywords Binary power plant ; ORC power plant ; Science ; Q ; Physics ; QC1-999 ; Heat ; QC251-338.5
    Subject code 621
    Publishing date 2015-03-01T00:00:00Z
    Publisher De Gruyter Open
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Pathologic aspects of skull base tumors.

    Marszałek, Andrzej / Szylberg, Łukasz / Wiśniewski, Sławomir

    Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

    2016  Volume 21, Issue 4, Page(s) 288–303

    Abstract: Skull base tumors form a highly heterogeneous group. As there are several structures in this anatomical site, a large number of different primary malignancies might develop, as well as a variety of secondary (metastatic) tumors. In this article, the most ...

    Abstract Skull base tumors form a highly heterogeneous group. As there are several structures in this anatomical site, a large number of different primary malignancies might develop, as well as a variety of secondary (metastatic) tumors. In this article, the most common malignancies are presented, along with a short histopathologic description. For some entities, an immunohistochemical profile is also given that should be helpful in proper diagnosis. As many pathologic diagnoses nowadays also include genetic studies, the most common genetic abnormalities in skull base tumors are presented.
    Language English
    Publishing date 2016-04-03
    Publishing country Poland
    Document type Journal Article ; Review
    ZDB-ID 2188087-6
    ISSN 1507-1367
    ISSN 1507-1367
    DOI 10.1016/j.rpor.2016.02.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A new mutation resulting in the truncation of the TRAF6-interacting domain of XEDAR: a possible novel cause of hypohidrotic ectodermal dysplasia.

    Wisniewski, Slawomir Aleksander / Trzeciak, Wieslaw Henryk

    Journal of medical genetics

    2012  Volume 49, Issue 8, Page(s) 499–501

    MeSH term(s) Adolescent ; Amino Acid Sequence ; DNA Mutational Analysis ; Eccrine Glands/pathology ; Ectodermal Dysplasia/genetics ; Ectodermal Dysplasia/pathology ; Genome, Human ; Humans ; Male ; Molecular Sequence Data ; Protein Interaction Domains and Motifs ; Sequence Deletion ; TNF Receptor-Associated Factor 6/genetics ; Xedar Receptor/genetics
    Chemical Substances EDA2R protein, human ; TNF Receptor-Associated Factor 6 ; Xedar Receptor
    Language English
    Publishing date 2012-08
    Publishing country England
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 220881-7
    ISSN 1468-6244 ; 0022-2593
    ISSN (online) 1468-6244
    ISSN 0022-2593
    DOI 10.1136/jmedgenet-2012-100877
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A novel mutation in the ED1 gene in a patient with X-linked hypohidrotic ectodermal dysplasia.

    Wawrzynek, Alicja / Slęzak, Ryszard / Wiśniewski, Slawomir A / Trzeciak, Wieslaw H

    International journal of dermatology

    2013  Volume 52, Issue 9, Page(s) 1121–1124

    MeSH term(s) Base Sequence ; Child, Preschool ; Computer Simulation ; Ectodermal Dysplasia 1, Anhidrotic/genetics ; Ectodysplasins/chemistry ; Ectodysplasins/genetics ; Ectodysplasins/metabolism ; Family Health ; Female ; Frameshift Mutation/genetics ; Humans ; Male ; Signal Transduction/genetics
    Chemical Substances EDA protein, human ; Ectodysplasins
    Language English
    Publishing date 2013-09
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/j.1365-4632.2011.05370.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Wykluczenia ojcostwa w świetle badań Katedry i Zakładu Medycyny Sadowej Akademii Medycznej w Poznaniu.

    Koralewska-Kordel, Małgorzata / Kordel, Krzysztof / Przybylski, Zygmunt / Wiśniewski, Sławomir A

    Archiwum medycyny sadowej i kryminologii

    2006  Volume 56, Issue 4, Page(s) 246–250

    Abstract: The study comprises the analysis of expert's hemogenetic reports carried out in the Department of Forensic Medicine, University of Medical Sciences in Poznan, in the years 1980-2004 and associated with paternity determination or exclusion. In the ... ...

    Title translation Paternity exclusion tests in the Department of Forensic Medicine, University of Medical Sciences in Poznan.
    Abstract The study comprises the analysis of expert's hemogenetic reports carried out in the Department of Forensic Medicine, University of Medical Sciences in Poznan, in the years 1980-2004 and associated with paternity determination or exclusion. In the analyzed period, the authors established 1064 cases of paternity exclusion in serological tests, 97 paternity exclusions in the HLA examinations, and 129 cases of paternity exclusions processed in DNA testing. On the base of gene frequencies, the theoretical chance of paternity exclusion was determined for every test. The significant usefulness of DNA testing in legal processes did not cause an increase in the percentage of paternity exclusions. Moreover, the authors observed a significant decrease in the number of paternity exclusions in comparison with results of serological tests (from 24.25% to 19.43%). With the drop in the number of births, the number of expert's reports significantly decreased.
    MeSH term(s) Academic Medical Centers ; DNA Fingerprinting/methods ; Forensic Medicine ; Humans ; Paternity ; Poland ; Polymorphism, Genetic ; Polymorphism, Restriction Fragment Length ; Probability ; Retrospective Studies ; Sequence Analysis, DNA/methods ; Tandem Repeat Sequences
    Language Polish
    Publishing date 2006-10
    Publishing country Poland
    Document type English Abstract ; Journal Article
    ZDB-ID 2780064-7
    ISSN 1689-1716 ; 0324-8267
    ISSN (online) 1689-1716
    ISSN 0324-8267
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Powypadkowe uszkodzenia narzadu ruchu a lekarskie rozbiezności w ustaleniu procentowego uszczerbku na zdrowiu ubezpieczonych.

    Kordel, Krzysztof / Stryjska, Małgorzata / Tuszyński, Krzysztof / Tomaszkiewicz, Jan / Wiśniewski, Sławomir

    Medycyna pracy

    2006  Volume 57, Issue 5, Page(s) 475–477

    Abstract: The authors present the results of an analysis of certification rules applied by insurance companies for the purpose of medical expertise. It was found that the percentage of health loss was very frequently understated by insurance companies as compared ... ...

    Title translation Post-accident injuries to the locomotor system and divergent medical opinions on the percentage of health loss in insured persons.
    Abstract The authors present the results of an analysis of certification rules applied by insurance companies for the purpose of medical expertise. It was found that the percentage of health loss was very frequently understated by insurance companies as compared with that decided by Polish courts. This mostly applied to diseases of musculoskeletal system and consequences of head injuries, which proved to be profitable for insurance companies. It was also common for medical experts working for insurance companies to use the lowest possible rates in estimating the loss of health. The authors emphasized the need to unify the rules and criteria for determining the percentage of health loss, or to inform insurance applicants about the fact that insurance companies have their own rules, which differ from those applied by courts.
    MeSH term(s) Accidents, Occupational/legislation & jurisprudence ; Accidents, Occupational/prevention & control ; Accidents, Occupational/statistics & numerical data ; Cost of Illness ; Diagnosis, Differential ; Disability Evaluation ; Disabled Persons/legislation & jurisprudence ; Disabled Persons/statistics & numerical data ; Expert Testimony/legislation & jurisprudence ; Humans ; Insurance, Disability/legislation & jurisprudence ; Musculoskeletal Diseases/diagnosis ; Musculoskeletal Diseases/epidemiology ; Musculoskeletal System/injuries ; Occupational Diseases/diagnosis ; Occupational Diseases/epidemiology ; Poland/epidemiology ; Risk Assessment ; Wounds, Nonpenetrating/diagnosis ; Wounds, Nonpenetrating/epidemiology
    Language Polish
    Publishing date 2006
    Publishing country Poland
    Document type English Abstract ; Journal Article
    ZDB-ID 128739-4
    ISSN 0465-5893
    ISSN 0465-5893
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Recent advances in understanding of the molecular basis of anhidrotic ectodermal dysplasia: discovery of a ligand, ectodysplasin A and its two receptors.

    Wiśniewski, Sławomir A / Kobielak, Agnieszka / Trzeciak, Wiesław H / Kobielak, Krzysztof

    Journal of applied genetics

    2002  Volume 43, Issue 1, Page(s) 97–107

    Abstract: Recent developments of the investigations on the molecular basis of anhidrotic ectodermal dysplasia are reviewed. Identification of the major product of the EDA gene (ectodysplasin A), a protein belonging to a group of TNF ligands, and molecular cloning ... ...

    Abstract Recent developments of the investigations on the molecular basis of anhidrotic ectodermal dysplasia are reviewed. Identification of the major product of the EDA gene (ectodysplasin A), a protein belonging to a group of TNF ligands, and molecular cloning of the cDNA, encoding its receptor (EDAR), a member of the TNF receptor family, are presented. The role of an alternative EDA receptor, localised on the X chromosome (XEDAR) in the developmental control of the differentiation of skin appendages, is discussed. Recent findings have elucidated the cause of the autosomal forms of EDA, both dominant and recessive, and indicated an important role of a signal transduction pathway involving a protein product of the NEMO gene and the transcription factor NFkappaB in the differentiation of skin appendages.
    MeSH term(s) Cloning, Molecular ; DNA, Complementary ; Ectodermal Dysplasia/genetics ; Ectodysplasins ; Humans ; Membrane Proteins/genetics
    Chemical Substances DNA, Complementary ; EDA protein, human ; Ectodysplasins ; Membrane Proteins
    Language English
    Publishing date 2002
    Publishing country Poland
    Document type Journal Article ; Review
    ISSN 1234-1983
    ISSN 1234-1983
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Novel mutation in the 5' splice site of exon 4 of the TCOF1 gene in the patient with Treacher Collins syndrome.

    Marszalek, Bozena / Wisniewski, Slawomir A / Wojcicki, Piotr / Kobus, Kazimierz / Trzeciak, Wieslaw H

    American journal of medical genetics. Part A

    2003  Volume 123A, Issue 2, Page(s) 169–171

    Abstract: Treacher Collins syndrome (TCS) is caused by mutations in the TCOF1 gene. This gene encodes a serine/alanine-rich protein called treacle. The structure of the entire TCOF1 gene was investigated in a patient with TCS. We detected a novel deletion ( ... ...

    Abstract Treacher Collins syndrome (TCS) is caused by mutations in the TCOF1 gene. This gene encodes a serine/alanine-rich protein called treacle. The structure of the entire TCOF1 gene was investigated in a patient with TCS. We detected a novel deletion (376delAAGGTGAGTGGGACTGCC) spanning 3 bp of exon 4 and 15 bp of the adjacent intronic sequence. This mutation causes premature termination of translation, resulting in a truncated protein devoid of nucleolar localization signal, and potential phosphorylation sites. Real-time PCR analysis showed different melting temperatures of the amplified fragment containing normal allele and that harboring the 18 bp deletion, thus providing a rapid screening assay for this and other deletions of the TCOF1 gene.
    MeSH term(s) Base Sequence ; Exons ; Humans ; Male ; Mandibulofacial Dysostosis/genetics ; Mutation/genetics ; Nuclear Proteins/genetics ; Pedigree ; Phosphoproteins/genetics ; Polymorphism, Single-Stranded Conformational ; Sequence Analysis, DNA ; Sequence Deletion/genetics
    Chemical Substances Nuclear Proteins ; Phosphoproteins ; TCOF1 protein, human
    Language English
    Publishing date 2003-11-01
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2108614-X
    ISSN 1552-4825
    ISSN 1552-4825
    DOI 10.1002/ajmg.a.20312
    Database MEDical Literature Analysis and Retrieval System OnLINE

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