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  1. Article: Midodrine - why don't you just work better?

    Anstey, Matthew / Shaefi, Shahzad / Wibrow, Bradley

    Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

    2023  Volume 24, Issue 4, Page(s) 296–297

    Language English
    Publishing date 2023-10-16
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2401976-8
    ISSN 1441-2772
    ISSN 1441-2772
    DOI 10.51893/2022.4.E
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6672: Show issues Location:
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  2. Article: Response to "What is a case-control study? Comment on 'Oral midodrine does not expedite liberation from protracted vasopressor infusions: A case-control study'".

    Wood, Alexander Jt / Rauniyar, Rashmi / Jacques, Angela / Palmer, Robert N / Wibrow, Bradley / Anstey, Matthew H

    Anaesthesia and intensive care

    2023  Volume 52, Issue 1, Page(s) 74

    MeSH term(s) Humans ; Midodrine ; Case-Control Studies ; Vasoconstrictor Agents/therapeutic use ; Infusions, Intravenous
    Chemical Substances Midodrine (6YE7PBM15H) ; Vasoconstrictor Agents
    Language English
    Publishing date 2023-11-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 187524-3
    ISSN 1448-0271 ; 0310-057X
    ISSN (online) 1448-0271
    ISSN 0310-057X
    DOI 10.1177/0310057X231197692
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1017: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: A Prospective Evaluation of Grip Strength Comparing a Low-Tech Method to Dynanometry in Preoperative Surgical Patients and Weak Intensive Care Patients.

    Shea, Mark J / Weightman, Anika / Wibrow, Bradley / Anstey, Matthew H

    Critical care research and practice

    2022  Volume 2022, Page(s) 3428851

    Abstract: Objective: Grip strength testing offers a mechanism to identify patients in whom frailty might be present, discriminate between robust elderly and vulnerable younger patients, and can be used as a tool to track changes in muscle bulk over the course of ... ...

    Abstract Objective: Grip strength testing offers a mechanism to identify patients in whom frailty might be present, discriminate between robust elderly and vulnerable younger patients, and can be used as a tool to track changes in muscle bulk over the course of an inpatient stay. We compared gold-standard quantitative grip strength measurement to a low-tech alternative, a manual bedside sphygmomanometer.
    Design: Under supervision, subjects performed hand-grip strength testing with each instrument. A mean score is calculated from three measurements on the dominant and nondominant hand.
    Results: Highly correlated results in both tertiary surgical outpatients (
    Conclusions: Modifying a manual bedside sphygmomanometer to measure grip strength is feasible and correlates well with a formal dynamometer in preadmission surgical patients and weak patients in the intensive care unit. The use of an existing, safe, and available device removes barriers to the measurement of weakness in patients and may encourage uptake of objective measurement in multiple settings.
    Language English
    Publishing date 2022-10-19
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2573849-5
    ISSN 2090-1313 ; 2090-1305
    ISSN (online) 2090-1313
    ISSN 2090-1305
    DOI 10.1155/2022/3428851
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Incidence and determinants of malpositioning tracheostomy tubes in critically ill adult patients.

    Ananthan, Prakkash P / Ho, Kwok M / Anstey, Matthew H / Wibrow, Bradley A

    Anaesthesia and intensive care

    2021  Volume 50, Issue 3, Page(s) 243–249

    Abstract: Tracheostomy tubes are chosen primarily based on their internal diameter; however, the length of the tube may also be important. We performed a prospective clinical audit of 30 critically ill patients following tracheostomy to identify the type of ... ...

    Abstract Tracheostomy tubes are chosen primarily based on their internal diameter; however, the length of the tube may also be important. We performed a prospective clinical audit of 30 critically ill patients following tracheostomy to identify the type of tracheostomy tube inserted, the incidence of malpositioning and the factors associated with the need to change the tracheostomy tube subsequently. Anthropometric neck measurements, distance between the skin and tracheal rings and the position of the tracheostomy cuff relative to the tracheal stoma were recorded and analysed. Malpositioning of the tracheostomy tube was noted in 20%, with a high riding cuff being the most common cause of malpositioning, resulting in an audible leak and a need to change the tracheostomy tube subsequently. A high riding cuff was more common when a small tracheostomy tube (e.g. Portex (Smiths Medical Australasia, Macquarie Park, NSW) ≤8.0 mm internal diameter with length <7.5 cm) was used, with risk further increased when the patient's skin to trachea depth was greater than 0.8 cm. Identifying a high riding cuff relative to the tracheal stoma confirmed by a translaryngeal bronchoscopy strongly predicted the risk of air leak and the need to change the tracheostomy tube subsequently. Our study suggests that when a small (and short) tracheostomy tube is planned for use, intraoperative translaryngeal bronchoscopy is warranted to exclude malpositioning of the tracheostomy tube with a high riding cuff.
    MeSH term(s) Adult ; Critical Illness ; Humans ; Incidence ; Intubation, Intratracheal/adverse effects ; Prospective Studies ; Trachea ; Tracheostomy
    Language English
    Publishing date 2021-12-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 187524-3
    ISSN 1448-0271 ; 0310-057X
    ISSN (online) 1448-0271
    ISSN 0310-057X
    DOI 10.1177/0310057X211039226
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1017: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Integrating the Choosing Wisely 5 Questions into Family Meetings in the Intensive Care Unit: A Randomized Controlled Trial Investigating the Effect on Family Perceived Involvement in Decision-Making.

    Drury, Ashleigh / Muscat, Danielle M / Wibrow, Bradley / Jacques, Angela / Anstey, Matthew

    Journal of patient experience

    2022  Volume 9, Page(s) 23743735221092623

    Abstract: Family members often act as surrogate decision makers for patients in the intensive care unit (ICU). The use of printed prompts may assist with families feeling empowered to fulfill this role. Prospective, randomized controlled trial in 3 ICUs in Western ...

    Abstract Family members often act as surrogate decision makers for patients in the intensive care unit (ICU). The use of printed prompts may assist with families feeling empowered to fulfill this role. Prospective, randomized controlled trial in 3 ICUs in Western Australia. In the intervention arm, families received the Choosing Wisely 5 questions as printed prompts prior to a family meeting, and the control arm did not receive prompts. The primary outcome was family perceived involvement in decision-making. Outcomes were measured using a survey. Sixty families participated in the study. The majority of families (87.1% control, 79.3% intervention;
    Language English
    Publishing date 2022-04-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2857285-3
    ISSN 2374-3743 ; 2374-3735
    ISSN (online) 2374-3743
    ISSN 2374-3735
    DOI 10.1177/23743735221092623
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Oral midodrine does not expedite liberation from protracted vasopressor infusions: A case-control study.

    Wood, Alexander Jt / Rauniyar, Rashmi / Jacques, Angela / Palmer, Robert N / Wibrow, Bradley / Anstey, Matthew H

    Anaesthesia and intensive care

    2022  , Page(s) 310057X221105297

    Abstract: Vasopressor dependence is a common problem affecting patients in the recovery phase of critical illness, often necessitating intensive care unit (ICU) admission and other interventions which carry associated risks. Midodrine is an orally administered ... ...

    Abstract Vasopressor dependence is a common problem affecting patients in the recovery phase of critical illness, often necessitating intensive care unit (ICU) admission and other interventions which carry associated risks. Midodrine is an orally administered vasopressor which is commonly used off-label to expedite weaning from vasopressor infusions and facilitate discharge from ICU. We performed a single-centre, case-control study to assess whether midodrine accelerated liberation from vasopressor infusions in patients who were vasopressor dependent. Cases were identified at the discretion of treating intensivists and received 20 mg oral midodrine every eight h from enrolment. Controls received placebo. Data on duration and dose of vasopressor infusion, haemodynamics and adverse events were collected. Between 2012 and 2019, 42 controls and 19 cases were recruited. Cases had received vasopressor infusions for a median of 94 h versus 29.3 h for controls, indicating prolonged vasopressor dependence amongst cases. Midodrine use in cases was not associated with faster weaning of intravenous (IV) vasopressors (26 h versus 24 h for controls,
    Language English
    Publishing date 2022-09-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 187524-3
    ISSN 1448-0271 ; 0310-057X
    ISSN (online) 1448-0271
    ISSN 0310-057X
    DOI 10.1177/0310057X221105297
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1017: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Intravenous vitamin C for vasoplegia: A double-blinded randomised clinical trial (VALENCIA trial).

    Anstey, Matthew H / Aljeaidi, Muhamad S / Palmer, Robert / Jacques, Angela / Mevavala, Bhaumik / Litton, Edward / Wibrow, Bradley

    Journal of critical care

    2023  Volume 78, Page(s) 154369

    Abstract: Purpose: To determine whether intravenous vitamin C compared with placebo, reduces vasopressor requirements in patients with vasoplegic shock.: Methods: Double-blinded, randomised clinical trial (RCT) conducted in two intensive care units in Perth, ... ...

    Abstract Purpose: To determine whether intravenous vitamin C compared with placebo, reduces vasopressor requirements in patients with vasoplegic shock.
    Methods: Double-blinded, randomised clinical trial (RCT) conducted in two intensive care units in Perth, Australia. Vasopressor requirements at enrolment needed to be >10 μg/min noradrenaline after hypovolaemia was clinically excluded. Patients received either intravenous 1.5 g sodium ascorbate in 100 ml normal saline every 6 h for 5 days, or placebo (100 ml normal saline). The primary outcome was duration of vasopressor usage in hours. Secondary outcomes were ICU and hospital length of stay, and 28-day, ICU and hospital mortality.
    Results: Of the 71 patients randomised (35 vitamin C, 36 placebo group), the median vasopressor duration was 44 h [95% CI, 37-54 h] and 55 h [95% CI, 33-66 h]) in the vitamin C and placebo groups (p = 0.057). ICU and hospital length of stay, mortality outcomes were similar between groups.
    Conclusions: In this RCT of patients with vasoplegic shock of at least moderate severity, the use of IV vitamin C compared with placebo did not significantly reduce the duration of vasopressors.
    Trial registration: Prospective registration - trial number ACTRN12617001392358.
    MeSH term(s) Humans ; Ascorbic Acid/therapeutic use ; Vasoplegia/drug therapy ; Saline Solution ; Vitamins/therapeutic use ; Administration, Intravenous ; Vasoconstrictor Agents/therapeutic use ; Double-Blind Method
    Chemical Substances Ascorbic Acid (PQ6CK8PD0R) ; Saline Solution ; Vitamins ; Vasoconstrictor Agents
    Language English
    Publishing date 2023-07-19
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 632818-0
    ISSN 1557-8615 ; 0883-9441
    ISSN (online) 1557-8615
    ISSN 0883-9441
    DOI 10.1016/j.jcrc.2023.154369
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2152: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Airway pressure release ventilation in mechanically ventilated patients with COVID-19: a multicenter observational study.

    Zorbas, John S / Ho, Kwok M / Litton, Edward / Wibrow, Bradley / Fysh, Edward / Anstey, Matthew H

    Acute and critical care

    2021  Volume 36, Issue 2, Page(s) 143–150

    Abstract: Background: Evidence prior to the coronavirus disease 2019 (COVID-19) pandemic suggested that, compared with conventional ventilation strategies, airway pressure release ventilation (APRV) can improve oxygenation and reduce mortality in patients with ... ...

    Abstract Background: Evidence prior to the coronavirus disease 2019 (COVID-19) pandemic suggested that, compared with conventional ventilation strategies, airway pressure release ventilation (APRV) can improve oxygenation and reduce mortality in patients with acute respiratory distress syndrome. We aimed to assess the association between APRV use and clinical outcomes among adult patients receiving mechanical ventilation for COVID-19 and hypothesized that APRV use would be associated with improved survival compared with conventional ventilation.
    Methods: A total of 25 patients with COVID-19 pneumonitis was admitted to intensive care units (ICUs) for invasive ventilation in Perth, Western Australia, between February and May 2020. Eleven of these patients received APRV. The primary outcome was survival to day 90. Secondary outcomes were ventilation-free survival days to day 90, mechanical complications from ventilation, and number of days ventilated.
    Results: Patients who received APRV had a lower probability of survival than did those on other forms of ventilation (hazard ratio, 0.17; 95% confidence interval, 0.03-0.89; P=0.036). This finding was independent of indices of severity of illness to predict the use of APRV. Patients who received APRV also had fewer ventilator-free survival days up to 90 days after initiation of ventilation compared to patients who did not receive APRV, and survivors who received APRV had fewer ventilator-free days than survivors who received other forms of ventilation. There were no differences in mechanical complications according to mode of ventilation.
    Conclusions: Based on the findings of this study, we urge caution with the use of APRV in COVID-19.
    Language English
    Publishing date 2021-05-04
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3003021-3
    ISSN 2586-6060 ; 2586-6052
    ISSN (online) 2586-6060
    ISSN 2586-6052
    DOI 10.4266/acc.2021.00017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Vitamin C and corticosteroids in viral pneumonia.

    Anstey, Matthew Harry / Luu, Jacky / Myers, Erina / Palmer, Robert N / Wibrow, Bradley / Ho, Kwok M

    Acute and critical care

    2021  Volume 36, Issue 2, Page(s) 169–171

    Language English
    Publishing date 2021-03-10
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3003021-3
    ISSN 2586-6060 ; 2586-6052
    ISSN (online) 2586-6060
    ISSN 2586-6052
    DOI 10.4266/acc.2020.01081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: A prospective comparison of peripheral metaraminol versus dilute noradrenaline in the intensive care unit.

    Ruchti, Vera Ew / Wibrow, Bradley A / Seet, Jason / Jacques, Angela / Jha, Nihar / Anstey, Matthew H

    Anaesthesia and intensive care

    2021  Volume 49, Issue 2, Page(s) 144–146

    MeSH term(s) Humans ; Intensive Care Units ; Metaraminol ; Myocardium ; Norepinephrine ; Prospective Studies
    Chemical Substances Metaraminol (818U2PZ2EH) ; Norepinephrine (X4W3ENH1CV)
    Language English
    Publishing date 2021-04-14
    Publishing country United States
    Document type Letter
    ZDB-ID 187524-3
    ISSN 1448-0271 ; 0310-057X
    ISSN (online) 1448-0271
    ISSN 0310-057X
    DOI 10.1177/0310057X20984794
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1017: Show issues Location:
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