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  1. Book ; Online ; Thesis: Functional regulation of the α7 nicotinic acetylcholine receptor by protein ineractions and tyrosine phosphorylation

    Wiesner, Andreas

    2006  

    Author's details by Andreas Wiesner
    Language English
    Size Online-Ressource (141 S), Ill
    Publisher ETH
    Publishing place Zürich
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Diss., Eidgenössische Technische Hochschule ETH Zürich, Nr. 16636--Zürich, 1663
    Database Former special subject collection: coastal and deep sea fishing

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  2. Article: Detection of tumor markers with ProteinChip technology.

    Wiesner, Andreas

    Current pharmaceutical biotechnology

    2004  Volume 5, Issue 1, Page(s) 45–67

    Abstract: The early diagnosis of cancer at a curable stage is crucial for the successful treatment of this disease. Most of the currently used tumor assays appear too late and rely on single biomarkers with high false-negative and/or false-positive rates. As an ... ...

    Abstract The early diagnosis of cancer at a curable stage is crucial for the successful treatment of this disease. Most of the currently used tumor assays appear too late and rely on single biomarkers with high false-negative and/or false-positive rates. As an additional burden for the patient, the traditional assays often require biopsy material instead of less invasively taken samples like serum. With the hope for more reliable DNA- and RNA-based screening tools, the research activities of the past 20 years have focused on the genomic characteristics of cancer cells. But, up to now, the output from this strategy has been disappointingly low and the disillusionment is paired with a return to proteins as the real key players in all physiological and pathological processes. Meanwhile, comparative protein profiling is generally acknowledged as a promising way for the detection of specific and predictive protein patterns reflecting certain stages of cancer without dependency on single markers. To meet the new technological demands, the ProteinChip Biomarker System was developed for the Expression Difference Mapping analysis of several hundreds of samples per day on a single, uncomplicated platform; with software support for the construction of multi-marker predictive models. The Interaction Discovery Mapping platform is introduced as the next methodical step for investigations about protein binding partners of possible importance in diagnosis and therapy. This review summarizes the current state in cancer diagnosis, provides an introduction into the ProteinChip technology, and gives an update on publications and research collaborations in SELDI-based tumor marker discovery.
    MeSH term(s) Animals ; Biomarkers, Tumor/analysis ; Biomarkers, Tumor/genetics ; Gene Expression Profiling/instrumentation ; Gene Expression Profiling/methods ; Humans ; Neoplasms/diagnosis ; Neoplasms/genetics ; Protein Array Analysis/instrumentation ; Protein Array Analysis/methods
    Chemical Substances Biomarkers, Tumor
    Language English
    Publishing date 2004-02-04
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2132197-8
    ISSN 1873-4316 ; 1389-2010
    ISSN (online) 1873-4316
    ISSN 1389-2010
    DOI 10.2174/1389201043489675
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6212: Show issues Location:
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  3. Book ; Thesis: Exchange Traded Funds in Deutschland und Effekte der europäischen Finanzmarktintegration

    Wiesner, Andreas

    (Schriftenreihe Finanzmanagement ; 58)

    2008  

    Author's details Andreas Wiesner
    Series title Schriftenreihe Finanzmanagement ; 58
    Keywords Indexfonds ; Indexderivat ; Aktienindex ; Wertpapierhandel ; Internationaler Finanzmarkt ; Marktintegration ; EU-Binnenmarkt ; Deutschland
    Language German
    Size XVIII, 322 S., graph. Darst., 210 mm x 148 mm, 425 gr.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Zugl.: Düsseldorf, Univ., Diss., 2008
    ISBN 9783830041276 ; 3830041276
    Database ECONomics Information System

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  4. Book ; Thesis: Functional regulation of the [alpha]-7 nicotinic acetylcholine receptor by protein ineractions and tyrosine phoshporylation

    Wiesner, Andreas

    2006  

    Author's details by Andreas Wiesner
    Language English
    Size 3 Mikrofiches, Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Eidgen. Techn. Hochschule, Diss.--Zürich, 2006
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  5. Book ; Online: Functional regulation of the α7 nicotinic acetylcholine receptor by protein ineractions and tyrosine phosphorylation

    Wiesner, Andreas

    2006  

    Abstract: Diss., Eidgenössische Technische Hochschule ETH Zürich, Nr. 16636, ... ...

    Abstract Diss., Eidgenössische Technische Hochschule ETH Zürich, Nr. 16636, 2006
    Keywords CHOLINERGE REZEPTOREN (NEUROLOGIE) ; NIKOTINISCHE REZEPTOREN (NEUROLOGIE) ; TYROSIN (AMINOSÄUREN ; BIOCHEMIE) ; PHOSPHORYLIERUNG ; DEPHOSPHORYLIERUNG (BIOCHEMIE) ; SIGNALTRANSDUKTION (BIOKOMMUNIKATION)
    Language English
    Publisher Zürich, ETH
    Publishing country ch
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  6. Book: Techniques in insect immunology

    Wiesner, Andreas

    (FITC ; 5)

    1998  

    Author's details editors, Andreas Wiesner ... [et al.]
    Series title FITC ; 5
    Keywords Insects/Immunology/Laboratory manuals. ; Insects/Immunology/Techniques.
    Language English
    Size 304, vi p. :, ill. ;, 28 cm.
    Publisher SOS Publications
    Publishing place Fair Haven, NJ
    Document type Book
    ISBN 1887052054 ; 9781887052054
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: A fast and reliable detection of indigo in historic and prehistoric textile samples.

    Kramell, Annemarie / Porbeck, Frank / Kluge, Ralph / Wiesner, Andreas / Csuk, René

    Journal of mass spectrometry : JMS

    2015  Volume 50, Issue 9, Page(s) 1039–1043

    Abstract: We present a method requiring no sample preparation for the direct identification of indigoid colorants in tiny amounts in ancient historic fabrics using ASAP®-MS. Exact determinations were completed in less than 1 min. Copyright © 2015 John Wiley & Sons, ...

    Abstract We present a method requiring no sample preparation for the direct identification of indigoid colorants in tiny amounts in ancient historic fabrics using ASAP®-MS. Exact determinations were completed in less than 1 min. Copyright © 2015 John Wiley & Sons, Ltd.
    Language English
    Publishing date 2015-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1221763-3
    ISSN 1096-9888 ; 1076-5174
    ISSN (online) 1096-9888
    ISSN 1076-5174
    DOI 10.1002/jms.3625
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4254: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 220: Show issues

    Order via subito

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  8. Article: Finanzmarktintegration und Geldpolitik

    Thieme, H. Jörg / Wiesner, Andreas

    Neupositionierung regionaler Führungskräfte , p. 59-71

    2009  , Page(s) 59–71

    Author's details H. Jörg Thieme und Andreas Wiesner
    Keywords Eurozone ; Finanzmarkt ; EU-Binnenmarkt ; Geldpolitik ; Internationaler Finanzmarkt ; Marktintegration ; EU-Staaten
    Language German
    Size graph. Darst.
    Publisher Lang
    Publishing place Frankfurt, M. [u.a.]
    Document type Article
    Database ECONomics Information System

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  9. Article: Simply buying the index?

    Smeets, Heinz Dieter / Wiesner, Andreas

    Die Bank , No. 11 , p. 22-27

    Exchange Traded Funds

    2009  , Issue 11, Page(s) 22–27

    Author's details Heinz Dieter Smeets; Andreas Wiesner
    Language German
    Size graph. Darst.
    Publisher Bank-Verlag
    Publishing place Köln
    Document type Article
    ZDB-ID 131636-9
    ISSN 0342-3182
    Database ECONomics Information System

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  10. Book ; Online: OntoCAPE

    Marquardt, Wolfgang / Morbach, Jan / Wiesner, Andreas / Yang, Aidong

    A Re-Usable Ontology for Chemical Process Engineering

    (RWTHedition)

    2010  

    Abstract: This book presents OntoCAPE, a formal domain ontology for chemical process engineering, which is based on a general upper ontology for engineering. The organization and structure of the ontology are depicted, and the conceptualizations of various topic ... ...

    Author's details by Wolfgang Marquardt, Jan Morbach, Andreas Wiesner, Aidong Yang
    Series title RWTHedition
    Abstract This book presents OntoCAPE, a formal domain ontology for chemical process engineering, which is based on a general upper ontology for engineering. The organization and structure of the ontology are depicted, and the conceptualizations of various topic areas are described in detail, including the areas of mereology, topology, systems theory, network systems, plant engineering, and others. Additionally, the rationale for choosing one particular conceptualization over the other is explicated, thus providing the reader with the necessary background knowledge for extending and customizing the ontology to his/her own purposes. Finally, the usage of the ontology is explained, and some sample applications are presented.
    Keywords Chemical engineering ; Chemistry ; Computer aided design ; Computer CAD ; Technik / Wissen Chemie ; Technik / Wissen Sonstiges
    Language English
    Size Online-Ressource, v.: digital
    Publisher Springer-Verlag Berlin Heidelberg
    Publishing place Berlin, Heidelberg
    Document type Book ; Online
    Note Includes bibliographical references and index
    ISBN 9783642046544 ; 9783642046544 ; 3642046541 ; 3642046541
    DOI 10.1007/978-3-642-04655-1
    Database Former special subject collection: coastal and deep sea fishing

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