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  1. Book: PET/PET-CT Evidenz zum Bedarf und zur Planung in Deutschland und Österreich: Update 2018

    Fuchs, Sabine / Grössmann, Nicole / Eckhardt, Helene / Busse, Reinhard / Wild, Claudia

    (Working papers in health policy and management ; Volume 12)

    2019  

    Author's details Sabine Fuchs, Nicole Grössmann, Helene Eckhardt, Reinhard Busse, Claudia Wild
    Series title Working papers in health policy and management ; Volume 12
    Collection
    Keywords Bedarfsplanung ; Entzündungserkrankungen ; Neurologie ; Nutzenbewertung ; Onkologie ; PET/PET-CT ; Positronen-Emissions-Tomographie ; evidence‐based medicine ; evidenzbasierte Medizin ; health technology assessment ; infections ; inflammatory indications ; needs-based planning ; neurology ; oncology ; positron emission tomography ; Deutschland ; Österreich ; Positronen-Emissions-Tomografie ; Computertomografie
    Subject Computertomographie ; CT ; Tomometrie ; Durchstrahlungscomputertomographie ; Durchstrahlungscomputertomografie ; Transmissionscomputertomographie ; Transmissionscomputertomografie ; Computerlaminographie ; Computerlaminografie ; CAT ; Computed axial tomography ; Computertomogramm ; Positronen-Emissions-Tomographie ; PET
    Subject code 616.075750943 ; 616.0757509436
    Language German
    Size 179 Seiten, 30 cm
    Publisher Universitätsverlag der TU Berlin
    Publishing place Berlin
    Publishing country Germany
    Document type Book
    HBZ-ID HT020431878
    ISBN 978-3-7983-3038-2 ; 3-7983-3038-7 ; 9783798330399 ; 3798330395
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: EUnetHTA's contribution to the new legal framework for health technology assessment cooperation in Europe.

    Imaz-Iglesia, Iñaki / Wild, Claudia

    International journal of technology assessment in health care

    2022  Volume 38, Issue 1, Page(s) e50

    Abstract: The history of the European cooperation on health technology assessment (HTA) has reached an important milestone with the adoption of the European HTA Regulation (HTA R) 2021/2282 in Dec 2021 (1). Its publication in the Official Journal of the European ... ...

    Abstract The history of the European cooperation on health technology assessment (HTA) has reached an important milestone with the adoption of the European HTA Regulation (HTA R) 2021/2282 in Dec 2021 (1). Its publication in the Official Journal of the European Union means a lot to those of us who wish to give HTA a stronger role in supporting health policy in favor of sustainable healthcare systems in Europe. The HTA R was prepared well by the European Commission with an impact assessment on policy options for enhanced EU cooperation on HTA (2) in 2017, followed by 3 years of negotiations with Member States. Now the ratified document stipulates that the European Cooperation on HTA will be based on a legal mandate and no longer stay a voluntary project-based initiative. It also means sustainability, since a permanent Secretariat at the European Commission will be set-up under the HTA R.
    MeSH term(s) Delivery of Health Care ; Europe ; European Union ; Health Policy ; Technology Assessment, Biomedical
    Language English
    Publishing date 2022-06-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 632573-7
    ISSN 1471-6348 ; 0266-4623
    ISSN (online) 1471-6348
    ISSN 0266-4623
    DOI 10.1017/S026646232200037X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Mid- and long-term (at least 12 months) follow-up of patients with spinal muscular atrophy (SMA) treated with nusinersen, onasemnogene abeparvovec, risdiplam or combination therapies: A systematic review of real-world study data.

    Erdos, Judit / Wild, Claudia

    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society

    2022  Volume 39, Page(s) 1–10

    Abstract: Objectives: This systematic review aimed to assess mid- and long-term (at least 12 months) real-world study data from all types of spinal muscular atrophy (SMA) patients treated with any of the approved drugs or combination therapies.: Methods: A ... ...

    Abstract Objectives: This systematic review aimed to assess mid- and long-term (at least 12 months) real-world study data from all types of spinal muscular atrophy (SMA) patients treated with any of the approved drugs or combination therapies.
    Methods: A systematic literature search was carried out in five databases. Two authors selected the studies based on pre-defined selection criteria and independently graded the risk of bias at study level.
    Results: Five hundred forty-six records were identified in the literature search and 22 studies (in 26 publications) were included in the analysis. Nusinersen, onasemnogene abeparvovec and combination therapies improved motor endpoints in SMA type 1 patients. SMA type 2 to type 4 patients treated with nusinersen showed stabilisation or small improvements in motor endpoints with some deterioration observed. Quality of life endpoints, such as respiratory and nutritional support were poorly reported on. Drug-related adverse events occurred rarely in all types of SMA patients with all assessed drugs. Mid- and long-term studies on risdiplam could not be identified.
    Conclusions: The large quantity of missing data and heterogeneity of studies hinder comparability. Although stability and further improvement on the long-term is still uncertain, the results from the included evidence, as well as from pivotal trials show a striking contrast to the natural progression of the disease.
    MeSH term(s) Follow-Up Studies ; Humans ; Muscular Atrophy, Spinal/drug therapy ; Oligonucleotides ; Quality of Life ; Spinal Muscular Atrophies of Childhood/drug therapy
    Chemical Substances Oligonucleotides ; nusinersen (5Z9SP3X666)
    Language English
    Publishing date 2022-04-30
    Publishing country England
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 1397146-3
    ISSN 1532-2130 ; 1090-3798
    ISSN (online) 1532-2130
    ISSN 1090-3798
    DOI 10.1016/j.ejpn.2022.04.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Robot-assisted surgery in thoracic and visceral indications: an updated systematic review.

    Grössmann-Waniek, Nicole / Riegelnegg, Michaela / Gassner, Lucia / Wild, Claudia

    Surgical endoscopy

    2024  Volume 38, Issue 3, Page(s) 1139–1150

    Abstract: Background: In surgical advancements, robot-assisted surgery (RAS) holds several promises like shorter hospital stays, reduced complications, and improved technical capabilities over standard care. Despite extensive evidence, the actual patient benefits ...

    Abstract Background: In surgical advancements, robot-assisted surgery (RAS) holds several promises like shorter hospital stays, reduced complications, and improved technical capabilities over standard care. Despite extensive evidence, the actual patient benefits of RAS remain unclear. Thus, our systematic review aimed to assess the effectiveness and safety of RAS in visceral and thoracic surgery compared to laparoscopic or open surgery.
    Methods: We performed a systematic literature search in two databases (Medline via Ovid and The Cochrane Library) in April 2023. The search was restricted to 14 predefined thoracic and visceral procedures and randomized controlled trials (RCTs). Synthesis of data on critical outcomes followed the Grading of Recommendations, Assessment, Development, and Evaluation methodology, and the risk of bias was evaluated using the Cochrane Collaboration's Tool Version 1.
    Results: For five out of 14 procedures, no evidence could be identified. A total of 20 RCTs and five follow-up publications met the inclusion criteria. Overall, most studies had either not reported or measured patient-relevant endpoints. The majority of outcomes showed comparable results between study groups. However, RAS demonstrated potential advantages in specific endpoints (e.g., blood loss), yet these findings relied on a limited number of low-quality studies. Statistically significant RAS benefits were also noted in some outcomes for certain indications-recurrence, quality of life, transfusions, and hospitalisation. Safety outcomes were improved for patients undergoing robot-assisted gastrectomy, as well as rectal and liver resection. Regarding operation time, results were contradicting.
    Conclusion: In summary, conclusive assertions on RAS superiority are impeded by inconsistent and insufficient low-quality evidence across various outcomes and procedures. While RAS may offer potential advantages in some surgical areas, healthcare decisions should also take into account the limited quality of evidence, financial implications, and environmental factors. Furthermore, considerations should extend to the ergonomic aspects for maintaining a healthy surgical environment.
    MeSH term(s) Humans ; Robotic Surgical Procedures/methods ; Laparoscopy/methods ; Length of Stay ; Hospitalization ; Delivery of Health Care
    Language English
    Publishing date 2024-02-02
    Publishing country Germany
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-023-10670-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Correspondence:

    Wild, Claudia / Götz, Gregor / Wernly, Bernhard

    International journal of cardiology. Heart & vasculature

    2023  Volume 49, Page(s) 101299

    Language English
    Publishing date 2023-11-27
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 2818464-6
    ISSN 2352-9067
    ISSN 2352-9067
    DOI 10.1016/j.ijcha.2023.101299
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Wearable cardioverter defibrillator for preventing sudden cardiac death in patients at risk: An updated systematic review of comparative effectiveness and safety.

    Goetz, Gregor / Wernly, Bernhard / Wild, Claudia

    International journal of cardiology. Heart & vasculature

    2023  Volume 45, Page(s) 101189

    Abstract: Objectives: To synthesise the available evidence of wearable cardioverter defibrillator (WCD) therapy as an add-on measure to optimal medical therapy (OMT) or as a replacement of hospital stay.: Methods: An update systematic review (SR) of ... ...

    Abstract Objectives: To synthesise the available evidence of wearable cardioverter defibrillator (WCD) therapy as an add-on measure to optimal medical therapy (OMT) or as a replacement of hospital stay.
    Methods: An update systematic review (SR) of comparative effectiveness and safety of WCD therapy was conducted. We included randomised controlled trials (RCT), prospective comparative studies and prospective uncontrolled studies with at least 100 patients. A narrative synthesis of the evidence was conducted.
    Results: One RCT (
    Conclusion: The only available RCT failed to show superiority of add-on use of WCD in post MI patients. Observational evidence shows that the compliance with WCD is good, but the evidence is afflicted with selection bias and the inclusion of diverse mixed patient populations diluting the ability to draw indication-specific conclusions on the utility of the device. More comparative data is needed to justify continuing or expanding use of WCD therapy.
    Language English
    Publishing date 2023-03-28
    Publishing country Ireland
    Document type Journal Article ; Review
    ZDB-ID 2818464-6
    ISSN 2352-9067
    ISSN 2352-9067
    DOI 10.1016/j.ijcha.2023.101189
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Zur patientennahen CRP-Messung im niedergelassenen Bereich

    Wild, Claudia / Hahn, Reinhard

    Kann die CRP-Messung bei niedergelassenen Ärzten zur Senkung der Antibiotika-Verschreibungen beitragen? ; Ein Assessment

    2000  

    Institution Institut für Technikfolgen-Abschätzung
    Author's details ITA, Institut für Technikfolgen-Abschätzung der Österreichischen Akademie der Wissenschaften. Projektleitung: Claudia Wild. Projektbearb.: Reinhard Hahn
    Keywords Niedergelassener Arzt ; C-reaktives Protein ; Messung
    Subject Messen ; Messverfahren ; Messmethode ; Messkonzept ; CRP ; Freiberuflich tätiger Arzt
    Language German
    Size II, 26 S.
    Publisher ITA
    Publishing place Wien
    Publishing country Austria
    Document type Book
    HBZ-ID HT013244637
    Database Catalogue ZB MED Medicine, Health

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  8. Book: Zahlenspiele in der Medizin

    Geiger-Gritsch, Sabine / Wild, Claudia

    eine kritische Analyse

    2010  

    Author's details Claudia Wild ... (Hg.). Die AutorInnen Sabine Geiger-Gritsch
    Keywords Medizin ; Gesundheitspolitik ; Arzneimittel ; Kritik
    Subject Fertigarzneimittel ; Therapeutikum ; Medikament ; Medukamente ; Pharmakon ; Pharmaka ; Arzneistoff ; Arzneimittelwirkstoff ; Arznei ; Pharmazeutikum ; Pharmazeutika ; Pharmazeutischer Wirkstoff ; Arzneidroge ; Gesundheit ; Humanmedizin ; Heilkunst ; Medicine
    Language German
    Size 223 S. : graf. Darst.
    Publisher Orac
    Publishing place Wien
    Publishing country Austria
    Document type Book
    HBZ-ID HT016291064
    ISBN 978-3-7015-0523-4 ; 3-7015-0523-3
    Database Catalogue ZB MED Medicine, Health

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  9. Article ; Online: Technologiebewertung digitaler Gesundheitsanwendungen für Refundierungsentscheidungen.

    Jeindl, Reinhard / Wild, Claudia

    Wiener medizinische Wochenschrift (1946)

    2021  Volume 174, Issue 3-4, Page(s) 44–52

    Abstract: Background: For most digital health applications (DiGA) only limited evidence of benefit is available. Currently available assessment frameworks do not cover all domains of a full health technology assessment (HTA). Additionally, technology-specific ... ...

    Title translation Technology assessment of digital health applications for reimbursement decisions.
    Abstract Background: For most digital health applications (DiGA) only limited evidence of benefit is available. Currently available assessment frameworks do not cover all domains of a full health technology assessment (HTA). Additionally, technology-specific aspects are required for the evaluation of DiGA. This work aimed to analyze the available assessment frameworks and design an evaluation process for DiGA.
    Methods: By a systematic literature search six assessment frameworks for DiGA were selected and analyzed. A hand search for strategies on DiGA of selected countries was conducted.
    Results: Of the analyzed assessment frameworks four described study designs. One assessment framework proposed a risk classification of DiGA. Aspects of artificial intelligence were assessed by one assessment framework. The analyzed countries have differing strategies for reimbursement of DiGA.
    Conclusion: Assessment frameworks for DiGA are very heterogeneous. There are efforts to find regulations for DiGA on a national level. When evaluating DiGA, a staged approach considering risk classes with subsequent evaluation of relevant HTA aspects is recommended.
    MeSH term(s) Humans ; Technology Assessment, Biomedical ; Digital Health ; Artificial Intelligence
    Language German
    Publishing date 2021-09-16
    Publishing country Austria
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 123613-1
    ISSN 1563-258X ; 0254-7945 ; 0043-5341
    ISSN (online) 1563-258X
    ISSN 0254-7945 ; 0043-5341
    DOI 10.1007/s10354-021-00881-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: ESWT: extrakorporale Stoßwellen-Therapie in der Orthopädie

    Khene, Mahmoud / Wild, Claudia

    ein assessment ; Endbericht

    1998  

    Institution Institut für Technikfolgen-Abschätzung
    Author's details Institut für Technikfolgen-Abschätzung der Österreichischen Akademie der Wissenschaften. Projektleiter: Claudia Wild. Projektbearb.: Mahmoud Khene
    Language German
    Size 39 S., 30 cm
    Publisher ITA
    Publishing place Wien
    Publishing country Austria
    Document type Book
    Note Literaturverz. S. 37 - 39
    HBZ-ID HT013362293
    Database Catalogue ZB MED Medicine, Health

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