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  1. Article ; Online: Two decades of bridging immunological divides.

    Williams, Ifor R

    Science immunology

    2020  Volume 5, Issue 52

    Keywords covid19
    Language English
    Publishing date 2020-09-29
    Publishing country United States
    Document type Editorial
    ISSN 2470-9468
    ISSN (online) 2470-9468
    DOI 10.1126/sciimmunol.abe6004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Celebrating twoness at

    Williams, Ifor R

    Science immunology

    2018  Volume 3, Issue 25

    Abstract: ... Science ... ...

    Abstract Science Immunology
    MeSH term(s) Allergy and Immunology ; Anniversaries and Special Events ; Periodicals as Topic
    Language English
    Publishing date 2018-07-03
    Publishing country United States
    Document type Editorial
    ISSN 2470-9468
    ISSN (online) 2470-9468
    DOI 10.1126/sciimmunol.aau2567
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Charting new horizons for

    Williams, Ifor R

    Science immunology

    2018  Volume 3, Issue 22

    Abstract: Charting new horizons ... ...

    Abstract Charting new horizons for
    MeSH term(s) Allergy and Immunology/trends ; Biomedical Research/trends ; Editorial Policies ; Humans ; Periodicals as Topic/trends
    Language English
    Publishing date 2018-04-04
    Publishing country United States
    Document type Editorial
    ISSN 2470-9468
    ISSN (online) 2470-9468
    DOI 10.1126/sciimmunol.aat2459
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Correction to: Intestinal M cells: Tireless samplers of enteric microbiota.

    Kanaya, Takashi / Williams, Ifor R / Ohno, Hiroshi

    Traffic (Copenhagen, Denmark)

    2020  Volume 21, Issue 9, Page(s) 617

    Language English
    Publishing date 2020-08-18
    Publishing country England
    Document type Published Erratum
    ZDB-ID 1483852-7
    ISSN 1600-0854 ; 1398-9219
    ISSN (online) 1600-0854
    ISSN 1398-9219
    DOI 10.1111/tra.12757
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  6. Article: Smothering fecal-oral coronavirus spread

    Funk, Michael / Williams, Ifor

    Science (Washington, DC, U. S.)

    Abstract: A review The research of Zang et al (Sci Immunol , 2020, 5, 3582) is reviewed Diarrhea is a common symptom in patients with coronavirus disease 2019 (COVID-19) Zang et al used organoid cultures of cells from the epithelial lining of human small and large ...

    Abstract A review The research of Zang et al (Sci Immunol , 2020, 5, 3582) is reviewed Diarrhea is a common symptom in patients with coronavirus disease 2019 (COVID-19) Zang et al used organoid cultures of cells from the epithelial lining of human small and large intestine as an in vitro model system with which to study viral entry and replication in enterocytes Mature enterocytes expressing the viral receptor were susceptible to productive infection, which was also stimulated by the expression of a protease involved in viral entry A subset of patients with COVID-19 shed high amounts of viral RNA in feces, but experiments with simulated human colonic fluid suggested that any shed virus would be rapidly inactivated during transit through the colon
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #659106
    Database COVID19

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  7. Article ; Online: Intestinal M cells: Tireless samplers of enteric microbiota.

    Kanaya, Takashi / Williams, Ifor R / Ohno, Hiroshi

    Traffic (Copenhagen, Denmark)

    2019  Volume 21, Issue 1, Page(s) 34–44

    Abstract: Mucosal immune responses in the inductive lymphoid tissues of the intestine begin with uptake of particulate antigens, including components of the gut microbiota by specialized antigen sampling M cells. M cells represent a distinct lineage of enterocytes ...

    Abstract Mucosal immune responses in the inductive lymphoid tissues of the intestine begin with uptake of particulate antigens, including components of the gut microbiota by specialized antigen sampling M cells. M cells represent a distinct lineage of enterocytes that arise from crypt stem cells in response to the cytokine receptor of NF-κB ligand (RANKL). Full differentiation of M cells requires the transcription factor Spi-B to yield mature M cells that express multiple receptors for bacteria including glycoprotein 2. M cell differentiation can be recapitulated in vitro using three-dimensional enteroid cultures of primary intestinal stem cells supplemented with RANKL. This article summarizes the current knowledge about the genesis of intestinal M cells and highlights some of the remaining unanswered questions about this enigmatic cell type.
    MeSH term(s) Cell Differentiation ; Humans ; Immunity, Mucosal ; Intestinal Mucosa ; Microbiota ; RANK Ligand
    Chemical Substances RANK Ligand
    Language English
    Publishing date 2019-11-28
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1483852-7
    ISSN 1600-0854 ; 1398-9219
    ISSN (online) 1600-0854
    ISSN 1398-9219
    DOI 10.1111/tra.12707
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  8. Article ; Online: In Science Journals.

    Vignieri, Sacha / Funk, Michael A / Jiang, Di / Osborne, Ian S / Delaney, John K / Malo, Courtney S / Alderton, Gemma / Lopez, Bianca / Kelly, Priscilla N / Nusinovich, Yevgeniya / Ray, L Bryan / Maroso, Mattia / Baek, Amy E / Williams, Ifor

    Science (New York, N.Y.)

    2023  Volume 380, Issue 6642, Page(s) 253–255

    Abstract: Highlights from ... ...

    Abstract Highlights from the
    Language English
    Publishing date 2023-04-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.adi3041
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    Zs.MG 77: Show issues

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  9. Article ; Online: In Science Journals.

    Malo, Courtney S / Kelly, Priscilla N / Suleymanov, Yury / Osborne, Ian S / Yeston, Jake / Szuromi, Phil / Grocholski, Brent / Williams, Ifor / Alderton, Gemma / Funk, Michael A / Scanlon, Seth Thomas / Foley, John F / Jiang, Di

    Science (New York, N.Y.)

    2023  Volume 380, Issue 6640, Page(s) 49–50

    Abstract: Highlights from ... ...

    Abstract Highlights from the
    Language English
    Publishing date 2023-04-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.adi1008
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  10. Article ; Online: In Science Journals.

    Smith, H Jesse / Williams, Ifor / Lavine, Marc S / Jiang, Di / Stern, Peter / Smith, Keith T / Norton, Melissa / Grocholski, Brent / Uzogara, Ekeoma / Vignieri, Sacha / Stajic, Jelena / Funk, Michael A / VanHook, Annalisa M

    Science (New York, N.Y.)

    2023  Volume 380, Issue 6644, Page(s) 491–492

    Abstract: Highlights from ... ...

    Abstract Highlights from the
    Language English
    Publishing date 2023-05-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.adi5208
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