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Article ; Online: Editorial for IJMHN: An application of the 'one health' approach for extreme weather events and mental health: Can the adoption of a 'one health' approach better prepare us for the predicted drought in parts of rural Australia?

Usher, Kim / Rice, Kylie / Williams, Jen

International journal of mental health nursing

2024 Volume 33, Issue 2, Page(s) 220–223

MeSH term(s)	Humans ; Droughts ; Extreme Weather ; Mental Health ; Australia ; Rural Population
Language	English
Publishing date	2024-02-20
Publishing country	Australia
Document type	Editorial
ZDB-ID	2076760-2
ISSN	1447-0349 ; 1445-8330
ISSN (online)	1447-0349
ISSN	1445-8330
DOI	10.1111/inm.13310
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Article ; Online: Synthesis and perspectives from the Ottawa 2022 conference on the assessment of competence.

Boursicot, Katharine / Kemp, Sandra / Norcini, John / Nadarajah, Vishna Devi / Humphrey-Murto, Susan / Archer, Elize / Williams, Jen / Pyörälä, Eeva / Möller, Riitta

Medical teacher

2023 Volume 45, Issue 9, Page(s) 978–983

Abstract: Introduction: The Ottawa Conference on the Assessment of Competence in Medicine and the Healthcare Professions was first convened in 1985 in Ottawa. Since then, what has become known as the Ottawa conference has been held in various locations around the ...

Abstract	Introduction: The Ottawa Conference on the Assessment of Competence in Medicine and the Healthcare Professions was first convened in 1985 in Ottawa. Since then, what has become known as the Ottawa conference has been held in various locations around the world every 2 years. It has become an important conference for the community of assessment - including researchers, educators, administrators and leaders - to share contemporary knowledge and develop international standards for assessment in medical and health professions education. Methods: The Ottawa 2022 conference was held in Lyon, France, in conjunction with the AMEE 2022 conference. A diverse group of international assessment experts were invited to present a symposium at the AMEE conference to summarise key concepts from the Ottawa conference. This paper was developed from that symposium. Results and discussion: This paper summarises key themes and issues that emerged from the Ottawa 2022 conference. It highlights the importance of the consensus statements and discusses challenges for assessment such as issues of equity, diversity, and inclusion, shifts in emphasis to systems of assessment, implications of 'big data' and analytics, and challenges to ensure published research and practice are based on contemporary theories and concepts.
MeSH term(s)	Humans ; Medicine ; Professional Competence
Language	English
Publishing date	2023-02-14
Publishing country	England
Document type	Journal Article
ZDB-ID	424426-6
ISSN	1466-187X ; 0142-159X
ISSN (online)	1466-187X
ISSN	0142-159X
DOI	10.1080/0142159X.2023.2174420
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Article: On becoming "Dr. Mom".

Williams, Jen

CJEM

2009 Volume 11, Issue 5, Page(s) 496–497

MeSH term(s)	Female ; Humans ; Internship and Residency ; Mothers/psychology ; Physicians, Women/psychology ; Pregnancy
Language	English
Publishing date	2009-08-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2059217-6
ISSN	1481-8035 ; 1481-8035 ; 1488-1543
ISSN (online)	1481-8035
ISSN	1481-8035 ; 1488-1543
DOI	10.1017/s1481803500011702
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Article ; Online: Rate of COVID-19 vaccination among patients with cancer who tested positive for severe acute respiratory syndrome-coronavirus 2: Analysis of the American Society of Clinical Oncology Registry.

Kurbegov, Dax / Bruinooge, Suanna S / Lei, Xiudong Jennifer / Kirkwood, M Kelsey / Dickson, Natalie / Hattiangadi, Trupti / Mileham, Kathryn F / Patrick, Alicia / Williams, Jen Hanley / Kaltenbaugh, Melinda / Gralow, Julie R / Garrett-Mayer, Elizabeth

Cancer

2023 Volume 129, Issue 11, Page(s) 1752–1762

Abstract: Background: The availability of safe and effective COVID-19 vaccines has enabled protections against serious COVID-19 outcomes, which are particularly important for patients with cancer. The American Society of Clinical Oncology Registry enabled the ... ...

Abstract	Background: The availability of safe and effective COVID-19 vaccines has enabled protections against serious COVID-19 outcomes, which are particularly important for patients with cancer. The American Society of Clinical Oncology Registry enabled the study of COVID-19 vaccine uptake in patients with cancer who were positive for severe acute respiratory syndrome-coronavirus 2. Methods: Medical oncology practices entered data on patients who were in cancer treatment. The cohort included patients who had severe acute respiratory syndrome-coronavirus 2 infection in 2020 and had visits and vaccine data after December 31, 2020. The primary end point was the time to first vaccination from January 1, 2021. Cumulative incidence estimates and Cox regression with death as a competing risk were used to describe the time to vaccine uptake and factors associated with vaccine receipt. Results: The cohort included 1155 patients from 56 practices. Among 690 patients who received the first vaccine dose, 92% received the second dose. The median time to vaccine was 99 days. After adjustment, older patients were associated with a higher likelihood of vaccination compared with patients younger than 50 years in January through March 2021, and age exhibited a linear effect, with older patients showing higher rates of vaccination. Metastatic solid tumors (hazard ratio [HR], 0.85; 95% confidence interval [CI], 0.73-0.98) or non-B-cell hematologic malignancies (HR, 0.71; 95% CI, 0.54-0.93) compared with nonmetastatic solid tumors, and any comorbidity (HR, 0.83; 95% CI, 0.73-0.95) compared with no comorbidity, were associated with lower vaccination rates. Area-level social determinants of health (lower education attainment and higher unemployment rates) were associated with lower vaccination rates. Conclusions: Patient age, cancer type, comorbidity, area-level education attainment, and unemployment rates were associated with differential vaccine uptake rates. These findings should inform strategies to communicate about vaccine safety and efficacy to patients with cancer.
MeSH term(s)	Humans ; COVID-19 Vaccines ; SARS-CoV-2 ; COVID-19/epidemiology ; COVID-19/prevention & control ; Vaccination ; Neoplasms/epidemiology ; Medical Oncology ; Registries
Chemical Substances	COVID-19 Vaccines
Language	English
Publishing date	2023-03-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	1429-1
ISSN	1097-0142 ; 0008-543X ; 1934-662X
ISSN (online)	1097-0142
ISSN	0008-543X ; 1934-662X
DOI	10.1002/cncr.34726
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Article ; Online: Pleural disease in the emergency department.

Weldon, Erin / Williams, Jen

Emergency medicine clinics of North America

2012 Volume 30, Issue 2, Page(s) 475–99, ix–x

Abstract: Emergency department presentations of pleural-based diseases are common, with severity ranging from mild to life threatening. The acute assessment, diagnosis, and treatment of pleural disease are critical as urgent invasive maneuvers such as ... ...

Abstract	Emergency department presentations of pleural-based diseases are common, with severity ranging from mild to life threatening. The acute assessment, diagnosis, and treatment of pleural disease are critical as urgent invasive maneuvers such as thoracocentesis and thoracostomy may be indicated. The emergency physician must have a systematic approach to these conditions that allows for rapid recognition, diagnosis, and definitive management. This article focuses on nontraumatic pleural disease, including diagnostic and treatment considerations of pleural effusion, empyema, primary spontaneous pneumothorax, secondary spontaneous pneumothorax, pediatric pneumothorax, spontaneous hemothorax, and spontaneous tension pneumothorax.
MeSH term(s)	Disease Management ; Emergencies ; Emergency Service, Hospital ; Humans ; Pleural Diseases/diagnosis ; Pleural Diseases/etiology ; Pleural Diseases/physiopathology ; Pleural Diseases/therapy ; Pneumothorax/diagnosis ; Pneumothorax/therapy
Language	English
Publishing date	2012-05
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	605637-4
ISSN	1558-0539 ; 0733-8627
ISSN (online)	1558-0539
ISSN	0733-8627
DOI	10.1016/j.emc.2011.10.012
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Article ; Online: An Assessment of the Feasibility and Utility of an ACCC-ASCO Implicit Bias Training Program to Enhance Racial and Ethnic Diversity in Cancer Clinical Trials.

Barrett, Nadine J / Boehmer, Leigh / Schrag, Janelle / Benson, Al B / Green, Sybil / Hamroun-Yazid, Leila / Howson, Alexandra / Matin, Khalid / Oyer, Randall A / Pierce, Lori / Jeames, Sanford E / Winkfield, Karen / Yang, Eddy S / Zwicker, Victoria / Bruinooge, Suanna / Hurley, Patricia / Williams, Jen Hanley / Guerra, Carmen E

JCO oncology practice

2023 Volume 19, Issue 4, Page(s) e570–e580

Abstract: Purpose: Cancer trial participants do not reflect the racial and ethnic diversity in the population of people with cancer in the United States. As a result of multiple system-, patient-, and provider-level factors, including implicit bias, cancer ... ...

Abstract	Purpose: Cancer trial participants do not reflect the racial and ethnic diversity in the population of people with cancer in the United States. As a result of multiple system-, patient-, and provider-level factors, including implicit bias, cancer clinical trials are not consistently offered to all potentially eligible patients. Materials and methods: ASCO and ACCC evaluated the utility (pre- and post-test knowledge changes) and feasibility (completion rates, curriculum satisfaction metrics, survey questions, and interviews) of a customized online training program combined with facilitated peer-to-peer discussion designed to help research teams identify their own implicit biases and develop strategies to mitigate them. Discussion focused on (1) specific elements of the training modules; (2) how to apply lessons learned; and (3) key considerations for developing a facilitation guide to support peer-to-peer discussions in cancer clinical research settings. We evaluated discussion via a qualitative assessment. Results: Participant completion rate was high: 49 of 50 participating cancer programs completed training; 126 of 129 participating individuals completed the training (98% response rate); and 119 completed the training and evaluations (92% response rate). Training increased the mean percentage change in knowledge scores by 19%-45% across key concepts (eg, causes of health disparities) and increased the mean percentage change in knowledge scores by 10%-31% about strategies/actions to address implicit bias and diversity concerns in cancer clinical trials. Knowledge increases were sustained at 6 weeks. Qualitative evaluation validated the utility and feasibility of facilitated peer-to-peer discussion. Conclusion: The pilot implementation of the training program demonstrated excellent utility and feasibility. Our evaluation affirms that an online training designed to raise awareness about implicit bias and develop strategies to mitigate biases among cancer research teams is feasible and can be readily implemented in cancer research settings.
MeSH term(s)	Humans ; United States ; Bias, Implicit ; Feasibility Studies ; Neoplasms/therapy
Language	English
Publishing date	2023-01-11
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3028198-2
ISSN	2688-1535 ; 2688-1527
ISSN (online)	2688-1535
ISSN	2688-1527
DOI	10.1200/OP.22.00378
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Article ; Online: Increasing Racial and Ethnic Equity, Diversity, and Inclusion in Cancer Treatment Trials: Evaluation of an ASCO-Association of Community Cancer Centers Site Self-Assessment.

JCO oncology practice

2023 Volume 19, Issue 4, Page(s) e581–e588

Abstract: Clinical trial participants do not reflect the racial and ethnic diversity of people with cancer. ASCO and the Association of Community Cancer Centers collaborated on a quality improvement study to enhance racial and ethnic equity, diversity, and ... ...

Abstract	Clinical trial participants do not reflect the racial and ethnic diversity of people with cancer. ASCO and the Association of Community Cancer Centers collaborated on a quality improvement study to enhance racial and ethnic equity, diversity, and inclusion (EDI) in cancer clinical trials. The groups conducted a pilot study to examine the feasibility, utility, and face validity of a two-part clinical trial site self-assessment to enable diverse types of research sites in the United States to (1) review internal data to assess racial and ethnic disparities in screening and enrollment and (2) review their policies, programs, procedures to identify opportunities and strategies to improve EDI. Overall, 81% of 62 participating sites were satisfied with the assessment; 82% identified opportunities for improvement; and 63% identified specific strategies and 74% thought the assessment had potential to help their site increase EDI. The assessment increased awareness about performance (82%) and helped identify specific strategies (63%) to increase EDI in trials. Although most sites (65%) were able to provide some data on the number of patients that consented, only two sites were able to provide all requested trial screening, offering, and enrollment data by race and ethnicity. Documenting and evaluating such data are critical steps toward improving EDI and are key to identifying and addressing disparities more broadly. ASCO and Association of Community Cancer Centers will partner with sites to better understand their processes and the feasibility of collecting screening, offering, and enrollment data in systematic and automated ways.
MeSH term(s)	Humans ; Diversity, Equity, Inclusion ; Ethnicity ; Neoplasms/therapy ; Pilot Projects ; Self-Assessment ; United States ; Clinical Trials as Topic
Language	English
Publishing date	2023-01-11
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3028198-2
ISSN	2688-1535 ; 2688-1527
ISSN (online)	2688-1535
ISSN	2688-1527
DOI	10.1200/OP.22.00560
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Article: A Highly Sensitive and Specific Probe-Based Real-Time PCR for the Detection of

Kuchipudi, Suresh V / Yon, Michele / Surendran Nair, Meera / Byukusenge, Maurice / Barry, Rhiannon M / Nissly, Ruth H / Williams, Jen / Pierre, Traci / Mathews, Tammy / Walner-Pendleton, Eva / Dunn, Patricia / Barnhart, Denise / Loughrey, Sean / Davison, Sherrill / Kelly, Dona J / Tewari, Deepanker / Jayarao, Bhushan M

Frontiers in veterinary science

2021 Volume 8, Page(s) 609126

Abstract: Avibacterium ... ...

Abstract	Avibacterium paragallinarum
Language	English
Publishing date	2021-04-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2834243-4
ISSN	2297-1769
ISSN	2297-1769
DOI	10.3389/fvets.2021.609126
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Article ; Online: Changes Over Time in COVID-19 Severity and Mortality in Patients Undergoing Cancer Treatment in the United States: Initial Report From the ASCO Registry.

Mileham, Kathryn F / Bruinooge, Suanna S / Aggarwal, Charu / Patrick, Alicia L / Davis, Christiana / Mesenhowski, Daniel J / Spira, Alexander / Clayton, Eric J / Waterhouse, David / Moore, Susan / Jazieh, Abdul-Rahman / Chen, Ronald C / Kaltenbaugh, Melinda / Williams, Jen Hanley / Gralow, Julie R / Schilsky, Richard L / Garrett-Mayer, Elizabeth

JCO oncology practice

2021 Volume 18, Issue 4, Page(s) e426–e441

Abstract: Purpose: People with cancer are at increased risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. ASCO's COVID-19 registry promotes systematic data collection across US oncology practices.: Methods: Participating practices ...

Abstract	Purpose: People with cancer are at increased risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. ASCO's COVID-19 registry promotes systematic data collection across US oncology practices. Methods: Participating practices enter data on patients with SARS-CoV-2 infection in cancer treatment. In this analysis, we focus on all patients with hematologic or regional or metastatic solid tumor malignancies. Primary outcomes are 30- and 90-day mortality rates and change over time. Results: Thirty-eight practices provided data for 453 patients from April to October 2020. Sixty-two percent had regional or metastatic solid tumors. Median age was 64 years. Forty-three percent were current or previous cigarette users. Patients with B-cell malignancies age 61-70 years had twice mortality risk (hazard ratio = 2.1 [95% CI, 1.3 to 3.3]) and those age > 70 years had 4.5 times mortality risk (95% CI, 1.8 to 11.1) compared with patients age ≤ 60 years. Association between survival and age was not significant in patients with metastatic solid tumors ( Conclusion: Older patients with B-cell malignancies were at increased risk for death (unlike older patients with metastatic solid tumors), as were all patients with cancer who smoke tobacco. Diagnosis of SARS-CoV-2 later in 2020 was associated with more favorable 30- and 90-day mortality, likely related to more asymptomatic cases and improved clinical management.
MeSH term(s)	Aged ; COVID-19/complications ; COVID-19/therapy ; Humans ; Middle Aged ; Neoplasms/complications ; Neoplasms/epidemiology ; Neoplasms/therapy ; Proportional Hazards Models ; Registries ; SARS-CoV-2 ; United States/epidemiology
Language	English
Publishing date	2021-10-25
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3028198-2
ISSN	2688-1535 ; 2688-1527
ISSN (online)	2688-1535
ISSN	2688-1527
DOI	10.1200/OP.21.00394
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Article ; Online: Characterization of Clostridium difficile isolates from human fecal samples and retail meat from Pennsylvania.

Varshney, Jyotika B / Very, Katherine J / Williams, Jen L / Hegarty, John P / Stewart, David B / Lumadue, Jeanne / Venkitanarayanan, Kumar / Jayarao, Bhushan M

Foodborne pathogens and disease

2014 Volume 11, Issue 10, Page(s) 822–829

Abstract: A study was conducted to determine the prevalence of Clostridium difficile and characterize C. difficile isolates from human stool and retail grocery meat samples. Human stool samples (n=317) were obtained from a clinical laboratory and meat samples (n= ... ...

Abstract	A study was conducted to determine the prevalence of Clostridium difficile and characterize C. difficile isolates from human stool and retail grocery meat samples. Human stool samples (n=317) were obtained from a clinical laboratory and meat samples (n=303) were collected from 8 retail grocery stores from October 2011 through September 2012 from Centre County of Pennsylvania and were examined for C. difficile. C. difficile was isolated from 16.7% of stool samples (n=317) and 6.9%, 11.5%, 14.5%, and 7.8% of beef (n=72), pork (n=78), turkey (n=76), and chicken (n=77) samples, respectively. Six different toxin gene profiles were detected in all human and meat isolates of C. difficile based on the presence or absence of toxin genes tcdA, tcdB, and cdtA and cdtB. Interestingly, 75.6% of the human C. difficile isolates lacked any deletion in the tcdC gene (139-bp), whereas a 39-bp deletion was observed in 61.3% of the C. difficile strains isolated from meat samples. C. difficile from meat samples were more susceptible to clindamycin, moxifloxacin, vancomycin, and metronidazole than C. difficile isolates from human samples. Twenty-five different ribotypes were identified in human and meat C. difficile isolates. In conclusion, significant genotypic and phenotypic differences were observed between human and meat isolates of C. difficile; however, a few C. difficile isolates from meat-in particular ribotypes 078, PA01, PA05, PA16, and PA22 with unique profiles (toxin gene, tcdC gene size and antimicrobial resistance profiles)-were similar to human C. difficile isolates.
MeSH term(s)	Animals ; Anti-Bacterial Agents ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Cattle ; Chickens ; Clindamycin/pharmacology ; Clostridium difficile/classification ; Clostridium difficile/isolation & purification ; Drug Resistance, Multiple, Bacterial ; Feces/microbiology ; Fluoroquinolones/pharmacology ; Gene Deletion ; Genes, Bacterial ; Genotype ; Humans ; Meat/microbiology ; Metronidazole/pharmacology ; Microbial Sensitivity Tests ; Pennsylvania ; Phenotype ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Ribotyping ; Swine ; Vancomycin/pharmacology
Chemical Substances	Anti-Bacterial Agents ; Bacterial Proteins ; Fluoroquinolones ; Repressor Proteins ; TcdC protein, Clostridium difficile ; Metronidazole (140QMO216E) ; Clindamycin (3U02EL437C) ; Vancomycin (6Q205EH1VU) ; moxifloxacin (U188XYD42P)
Language	English
Publishing date	2014-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2148479-X
ISSN	1556-7125 ; 1535-3141
ISSN (online)	1556-7125
ISSN	1535-3141
DOI	10.1089/fpd.2014.1790
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