Book ; Online ; E-Book: Precision psychiatry
using neuroscience insights to inform personally tailored, measurement-based care
2022
Abstract: An estimated 970 million people worldwide experienced a mental or substance disorder in the past few years, and one in five people in the United States live with a mental disorder at some point in their lives. Progress in precision medicine in ... ...
| Author's details | edited by Leanne M. Williams, Laura M. Hack |
|---|---|
| Abstract | "An estimated 970 million people worldwide experienced a mental or substance disorder in the past few years, and one in five people in the United States live with a mental disorder at some point in their lives. Progress in precision medicine in disciplines outside of psychiatry, such as oncology and cardiology, has inspired progress reflected in the contributions in this book. In these disciplines, biomarkers are combined with clinical features to stratify patients into subtypes that are more coherent than are overarching diagnostic categories. This approach allows for identifying subtypes that are underserved by available therapies and allows for developing novel therapies aimed at targets that are based on specific mechanisms that affect measurable outcomes and that are closer to underlying disease processes than are traditional clinical endpoints.^ This book illustrates timely advances emerging in precision medicine in psychiatry, focusing on mood and anxiety disorders as well as schizophrenia in adults. Contributors to this book have a common view that a neuroscience- and data-informed approach is required to advance precision medicine in psychiatry. This book includes case examples of the applications of the topics covered, and the last chapter discusses the critical role of neuroscience education in precision psychiatry. The authors represent a range of expertise and have played fundamental roles in the development of the discipline of precision psychiatry. Biomarkers in neuroimaging, electrophysiology, and peripheral serum, as well as variations in genetic markers, neurocognition, and behavior, are covered, as is the importance of computational approaches and machine learning.^ The authors also review the precise application of multiple treatment modalities that include pharmacotherapy, cognitive-behavioral therapy, neurostimulation, and cognitive training programs on the individual level. Finally, this book addresses issues of scalability and implementation, including the need for the tests to have analytic and clinical validity as well as clinical utility"-- |
| Keywords | Neuropsychiatry / methods ; Precision Medicine / methods ; Biomarkers / analysis |
| Subject code | 616.8 |
| Language | English |
| Size | 1 Online-Ressource (xxvii, 264 Seiten) |
| Edition | First edition |
| Publisher | American Psychiatric Association Publishing |
| Publishing place | Washington, DC |
| Publishing country | United States |
| Document type | Book ; Online ; E-Book |
| Note | Includes bibliographical references and index |
| Remark | Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer |
| HBZ-ID | HT021128509 |
| ISBN | 9781615374458 ; 9781615371587 ; 1615374450 ; 1615371583 |
| Database | ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture |
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