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  1. Book ; Conference proceedings: Trauma & memory

    Williams, Linda M.

    [most of the chapters in ths volume were originaly presented at a conference held in Durham, N.H., in June 1996]

    1999  

    Author's details Linda M. Williams ..., eds
    Keywords Posttraumatisches Stresssyndrom ; Gedächtnis ; Psychisches Trauma
    Subject Erinnerungsvermögen ; Psychische Traumatisierung ; Psychotrauma ; Trauma ; Posttraumatisch-psychoreaktives Stresssyndrom ; Posttraumatic psychoreactive stress syndrome ; Posttraumatische Belastungsreaktion ; Posttraumatic stress disorder ; Posttraumatische Belastungsstörung ; PTSD ; PTB ; PTBS
    Language English
    Size XIII, 384 S. : graph. Darst.
    Publisher SAGE
    Publishing place Thousand Oaks, Calif u.a.
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT009052826
    ISBN 0-7619-0771-8 ; 0-7619-0772-6 ; 978-0-7619-0771-8 ; 978-0-7619-0772-5
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Exploring health professionals' viewpoint of provision of nutrition advice for women with endometrial cancer.

    Williams, Linda / Henry, Claire / Simcock, Bryony / Filoche, Sara

    The New Zealand medical journal

    2023  Volume 136, Issue 1583, Page(s) 40–54

    Abstract: Aims: The aim of this study was to explore barriers and facilitators to delivery and uptake of nutrition advice to women diagnosed with endometrial cancer from a health professionals' viewpoint.: Methods: Fifteen semi-structured interviews with ... ...

    Abstract Aims: The aim of this study was to explore barriers and facilitators to delivery and uptake of nutrition advice to women diagnosed with endometrial cancer from a health professionals' viewpoint.
    Methods: Fifteen semi-structured interviews with health professionals with experience in providing healthcare to women diagnosed with endometrial cancer were audio-recorded and transcribed. Interviews were analysed using reflexive thematic analysis. Topics included high weight as a risk factor for endometrial cancer, nutrition information sources, and barriers and facilitators to delivering nutrition advice in clinical care.
    Results: Four themes were identified. The first three exist as barriers to women receiving nutrition advice-how to navigate conversations about high weight, access to limited resourcing and health professionals feeling powerless to overcome system influences. The fourth theme identified a community approach need to facilitate a supportive environment and share knowledge.
    Conclusions: This study, through the lens of health professionals, highlights barriers to the delivery and uptake of nutrition advice at the patient, community and system levels. Enhancing survivorship for women after the diagnosis of endometrial cancer may be enabled by further understanding of how to overcome barriers and promote facilitators. Communication and partnership with women are imperative to achieving this.
    MeSH term(s) Humans ; Female ; New Zealand ; Delivery of Health Care ; Risk Factors ; Communication ; Health Personnel ; Endometrial Neoplasms ; Qualitative Research
    Language English
    Publishing date 2023-10-06
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 390590-1
    ISSN 1175-8716 ; 0028-8446 ; 0110-7704
    ISSN (online) 1175-8716
    ISSN 0028-8446 ; 0110-7704
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Increasing incidence of endometrial cancer in Aotearoa New Zealand: Health professionals' perspective.

    Williams, Linda / Henry, Claire / Simcock, Bryony / Filoche, Sara

    The Australian & New Zealand journal of obstetrics & gynaecology

    2023  Volume 64, Issue 2, Page(s) 114–119

    Abstract: Background: The incidence of endometrial cancer is globally increasing. Aotearoa New Zealand is no exception with a 59% increase in cases over that last ten years.: Aims: We report a sub-set of themes which pertain to provider reflections of rising ... ...

    Abstract Background: The incidence of endometrial cancer is globally increasing. Aotearoa New Zealand is no exception with a 59% increase in cases over that last ten years.
    Aims: We report a sub-set of themes which pertain to provider reflections of rising endometrioid-type endometrial cancer incidence in individuals with high weight.
    Materials and methods: Fifteen semi-structured interviews with healthcare professionals experienced in providing care to women with endometrial cancer were audio-recorded and transcribed. Interviews were analysed using reflexive thematic analysis.
    Results: Two main themes emerged: (1) concerns for the future; and (2) impact on fertility and treatment options. Healthcare professionals discussed rising incidence in younger people and a need for increased awareness about the association of excess weight as a risk factor for developing the disease. The concern extended to workforce and equipment shortfalls of meeting the needs of individuals with higher weight, which subsequently influenced treatment options, health outcomes and survivorship.
    Conclusions: Rising incidence of endometrial cancer in individuals with high weight presents multiple chances for inequitable access and health outcomes over the care continuum for endometrial cancer. Action is required to address incidence, awareness, access to equitable and inclusive treatment, and survivorship.
    MeSH term(s) Humans ; Female ; New Zealand/epidemiology ; Incidence ; Risk Factors ; Endometrial Neoplasms/epidemiology ; Endometrial Neoplasms/therapy ; Qualitative Research ; Health Personnel
    Language English
    Publishing date 2023-09-22
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 390815-x
    ISSN 1479-828X ; 0004-8666
    ISSN (online) 1479-828X
    ISSN 0004-8666
    DOI 10.1111/ajo.13751
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Implementation Science.

    Williams, Linda S / Vickrey, Barbara G

    Stroke

    2021  Volume 52, Issue 12, Page(s) 4054–4056

    MeSH term(s) Humans ; Implementation Science ; Stroke
    Language English
    Publishing date 2021-11-04
    Publishing country United States
    Document type Letter ; Review
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.121.033971
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Coming back for more: factors linked to higher participation among Veterans with chronic pain in an innovative VA-YMCA wellness clinic.

    Preddie, Alaina K / Donnelly, Claire E / Miech, Edward J / Myers, Laura J / Williams, Linda S / Damush, Teresa M

    BMJ open quality

    2024  Volume 13, Issue 1

    Abstract: In 2019, the Indianapolis VA developed a Wellness Clinic in partnership with the Young Men's Christian Associations (YMCA) to comprehensively address Veterans' chronic pain. Our specific aims were twofold: (1) to evaluate the implementation of the ... ...

    Abstract In 2019, the Indianapolis VA developed a Wellness Clinic in partnership with the Young Men's Christian Associations (YMCA) to comprehensively address Veterans' chronic pain. Our specific aims were twofold: (1) to evaluate the implementation of the Veterans Health Indiana (VHI) Wellness Clinic on patient utilisation and (2) to evaluate patient functioning.We conducted a mixed-methods evaluation, which included the extraction of VA administrative data to identify a patient cohort; the conduct of chart review to extract clinic utilisation, clinical outcomes collected during pain-related healthcare services and comorbidities; and semistructured interviews with Veteran patients who used the VHI Wellness Clinic in different patterns to identify challenges and facilitators to clinic utilisation. We applied configurational analysis to a Veteran sample who had their first visit to the VHI Wellness Clinic in March/April 2019 to pinpoint difference-making factors linked to Veterans' successful participation.The cohort included 312 Veterans (83% male), mean age of 55.4 years. The configurational model included six factors: participation in physical therapy, pain psychology or pain education sessions (22%); presence of any 'no-shows' (57% had 0); history of depression (39%) and clinic referral source (51% self-referred from primary care). The model consisted of four different pathways to successful participation, explaining 60% of cases in the higher-participation group with 86% consistency. Patient outcomes after clinic utilisation demonstrated a significant reduction in self-reported pain and pain catastrophising across time. Moreover, patients reported distance to clinic as both a facilitator and challenge.This mixed-methods analysis identified specific biopsychosocial factors and clinical services directly linked to higher Veteran participation in a new VA-YMCA Wellness Clinic. The VHI Wellness Clinic embedded within a YMCA facility is a feasible and efficacious healthcare delivery model for primary care patients experiencing chronic pain. Additional marketing to clinical providers for referrals and to patients to extend its reach is needed.
    MeSH term(s) United States ; Humans ; Male ; Middle Aged ; Female ; Veterans ; Chronic Pain/therapy ; United States Department of Veterans Affairs ; Self Report
    Language English
    Publishing date 2024-01-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2399-6641
    ISSN (online) 2399-6641
    DOI 10.1136/bmjoq-2023-002523
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Predictors of non-offending caregiver support in cases of child sexual abuse.

    Johnson, Hannah M / Block, Stephanie D / Gonzales, Joseph E / Ramsey, Michaela G / Shockley, Kristy L / Williams, Linda M

    Child abuse & neglect

    2024  Volume 149, Page(s) 106650

    Abstract: Background: In cases of child sexual abuse (CSA), a supportive non-offending caregiver (NOC) is important for the child's overall well-being and adjustment. NOC support is also predictive of CSA cases moving forward to prosecution. Limited research has ... ...

    Abstract Background: In cases of child sexual abuse (CSA), a supportive non-offending caregiver (NOC) is important for the child's overall well-being and adjustment. NOC support is also predictive of CSA cases moving forward to prosecution. Limited research has studied CSA case factors in relation to NOC supportive behaviors across numerous support dimensions.
    Objective: We investigated what case details predicted four different dimensions of caregiver support.
    Participants and settings: In this secondary analysis, a sample of 500 CSA cases from four prosecutors' offices in one New England state from 2009 to 2013 were randomly selected and reviewed.
    Method: This study used regression analysis to test 13 case characteristics (e.g., disclosure of abuse, NOC's relationship to perpetrator) as predictors of NOC support dimensions: belief of victim, support of prosecution, protection of victim, and whether a child protective services neglect report was filed against the caregiver.
    Results: When the perpetrator was their romantic partner, the NOC was less likely to protect and believe the child victim, yet more likely to support prosecution. NOCs were more likely to demonstrate belief when the child disclosed to them first.
    Conclusion: Our findings reveal the importance of the key case factors that are predictive of NOC support. This is the first study to examine these many case factors in relation to these four dimensions of support. Knowledge of these predictors can play an important role in better understanding the complexity of NOC support predictors and facilitating interventions designed to enhance such support.
    MeSH term(s) Child ; Humans ; Child Abuse, Sexual ; Caregivers ; Child Abuse ; Disclosure ; Regression Analysis
    Language English
    Publishing date 2024-01-27
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 799143-5
    ISSN 1873-7757 ; 0145-2134
    ISSN (online) 1873-7757
    ISSN 0145-2134
    DOI 10.1016/j.chiabu.2024.106650
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Trends in Outpatient Treatment for Depression in Survivors of Stroke in the United States, 2004-2017.

    Dong, Liming / Mezuk, Briana / Williams, Linda S / Lisabeth, Lynda D

    Neurology

    2022  Volume 98, Issue 22, Page(s) e2258–e2267

    Abstract: Background and objectives: Depression is highly prevalent and persistent among survivors of stroke. It is unknown how treatment for depression among survivors of stroke has changed in the evolving context of stroke care and mental health care in the ... ...

    Abstract Background and objectives: Depression is highly prevalent and persistent among survivors of stroke. It is unknown how treatment for depression among survivors of stroke has changed in the evolving context of stroke care and mental health care in the general US population, especially among vulnerable sociodemographic subgroups who bear higher risks for stroke and unfavorable poststroke outcomes and experience disparities in access to and quality of stroke and mental health care. The study examined temporal trends in outpatient treatment for depression among survivors of stroke in the United States between 2004 and 2017.
    Methods: The study sample consisted of 10,243 adult survivors of stroke and 264,645 adults without stroke drawn from the Medical Expenditure Panel Survey, a nationally representative survey in the United States. Trends in outpatient treatment for depression and potential unmet needs in the stroke population, including variations across sociodemographic subgroups, were examined and compared with the nonstroke population.
    Results: The rate of receipt of outpatient treatment for depression among survivors of stroke was 17.7% in 2004-2005 and 16.0% in 2016-2017 (adjusted odds ratio for period change [aOR] 0.90, 95% CI 0.71-1.15). Older, male, non-Hispanic Black, and Hispanic survivors of stroke were less likely to receive treatment for depression. Approximately two-thirds of survivors of stroke who screened positive for depression received no outpatient treatment during a calendar year. The sociodemographic disparities and treatment gap persisted during the study period, which differed from the nonstroke population. Among survivors of stroke who received any treatment for depression, there was a remarkable increase in use of psychotherapy (aOR 2.26, 95% CI 1.28-4.01), despite its less frequent use compared with pharmacotherapy.
    Discussion: Although depression is common after stroke, the majority of survivors of stroke receive no treatment for depression. This gap has remained largely unchanged over past decades, with substantial sociodemographic differences. Efforts are needed to improve depression care for survivors of stroke and reduce disparities.
    MeSH term(s) Adult ; Ambulatory Care ; Depression/epidemiology ; Depression/psychology ; Depression/therapy ; Humans ; Male ; Outpatients ; Stroke/complications ; Stroke/epidemiology ; Stroke/therapy ; Survivors ; United States/epidemiology
    Language English
    Publishing date 2022-04-04
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000200286
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Evaluation of the association of area-level socioeconomic deprivation and breast cancer recurrence by oestrogen receptor subtypes in Scotland.

    Dunlop, Hayley M / Williams, Linda J / Hall, Peter S / Barber, Matthew / Dodds, Christine / Figueroa, Jonine D

    Breast cancer research : BCR

    2023  Volume 25, Issue 1, Page(s) 106

    Abstract: Background: Women from socioeconomically deprived areas have lower breast cancer (BC) incidence rates for screen-detected oestrogen receptor (ER) + tumours and higher mortality for select tumour subtypes. We aimed to determine if ipsilateral breast ... ...

    Abstract Background: Women from socioeconomically deprived areas have lower breast cancer (BC) incidence rates for screen-detected oestrogen receptor (ER) + tumours and higher mortality for select tumour subtypes. We aimed to determine if ipsilateral breast cancer recurrence (IBR) differs by Scottish Index of Multiple Deprivation (SIMD) quintile and tumour subtype in Scotland.
    Methods: Patient data for primary invasive BC diagnosed in 2007-2008 in Scotland was analysed. Manual case-note review for 3495 patients from 10 years post-diagnosis was used. To determine the probability of IBR while accounting for the competing risk of death from any cause, cumulative incidence functions stratified by ER subtype and surgery were plotted. Multivariable Cox Proportional Hazards models were used to estimate the association of SIMD accounting for other predictors of IBR.
    Results: Among 2819 ER + tumours, 423 patients had a recurrence and 438 died. SIMD was related to death (p = 0.018) with the most deprived more likely to have died in the 10-year period (17.7% vs. 12.9%). We found no significant differences by SIMD in prognostic tumour characteristics (grade, TNM stage, treatment, screen-detection) or risk of IBR. Among 676 patients diagnosed with ER- tumours, 105 died and 185 had a recurrence. We found no significant differences in prognostic tumour characteristics by SIMD except screen detection with the most deprived more likely than the least to have their tumours detected from screening (46.9% vs. 28%, p = 0.03). Among patients with ER- tumours, 50% had mastectomy and the most deprived had increased 5-year IBR risk compared to the least deprived (HR 3.03 [1.41-6.53]).
    Conclusions: IBR is not a major contributor to mortality differences by SIMD for the majority of BC patients in our study. The lack of inequities in IBR are likely due to standardised treatment protocols and access to healthcare. The association with socioeconomic deprivation and recurrence for ER- tumours requires further study.
    MeSH term(s) Humans ; Female ; Breast Neoplasms/pathology ; Receptors, Estrogen ; Mastectomy ; Breast/pathology ; Socioeconomic Factors
    Chemical Substances Receptors, Estrogen
    Language English
    Publishing date 2023-10-03
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Intramural
    ZDB-ID 2015059-3
    ISSN 1465-542X ; 1465-5411
    ISSN (online) 1465-542X
    ISSN 1465-5411
    DOI 10.1186/s13058-023-01704-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Breast-Conserving Surgery with or without Irradiation in Early Breast Cancer.

    Kunkler, Ian H / Williams, Linda J / Jack, Wilma J L / Cameron, David A / Dixon, J Michael

    The New England journal of medicine

    2023  Volume 388, Issue 7, Page(s) 585–594

    Abstract: Background: Limited level 1 evidence is available on the omission of radiotherapy after breast-conserving surgery in older women with hormone receptor-positive early breast cancer receiving adjuvant endocrine therapy.: Methods: We performed a phase 3 ...

    Abstract Background: Limited level 1 evidence is available on the omission of radiotherapy after breast-conserving surgery in older women with hormone receptor-positive early breast cancer receiving adjuvant endocrine therapy.
    Methods: We performed a phase 3 randomized trial of the omission of irradiation; the trial population included women 65 years of age or older who had hormone receptor-positive, node-negative, T1 or T2 primary breast cancer (with tumors ≤3 cm in the largest dimension) treated with breast-conserving surgery with clear excision margins and adjuvant endocrine therapy. Patients were randomly assigned to receive whole-breast irradiation (40 to 50 Gy) or no irradiation. The primary end point was local breast cancer recurrence. Regional recurrence, breast cancer-specific survival, distant recurrence as the first event, and overall survival were also assessed.
    Results: A total of 1326 women were enrolled; 658 were randomly assigned to receive whole-breast irradiation and 668 to receive no irradiation. The median follow-up was 9.1 years. The cumulative incidence of local breast cancer recurrence within 10 years was 9.5% (95% confidence interval [CI], 6.8 to 12.3) in the no-radiotherapy group and 0.9% (95% CI, 0.1 to 1.7) in the radiotherapy group (hazard ratio, 10.4; 95% CI, 4.1 to 26.1; P<0.001). Although local recurrence was more common in the group that did not receive radiotherapy, the 10-year incidence of distant recurrence as the first event was not higher in the no-radiotherapy group than in the radiotherapy group, at 1.6% (95% CI, 0.4 to 2.8) and 3.0% (95% CI, 1.4 to 4.5), respectively. Overall survival at 10 years was almost identical in the two groups, at 80.8% (95% CI, 77.2 to 84.3) with no radiotherapy and 80.7% (95% CI, 76.9 to 84.3) with radiotherapy. The incidence of regional recurrence and breast cancer-specific survival also did not differ substantially between the two groups.
    Conclusions: Omission of radiotherapy was associated with an increased incidence of local recurrence but had no detrimental effect on distant recurrence as the first event or overall survival among women 65 years of age or older with low-risk, hormone receptor-positive early breast cancer. (Funded by the Chief Scientist Office of the Scottish Government and the Breast Cancer Institute, Western General Hospital, Edinburgh; ISRCTN number, ISRCTN95889329.).
    MeSH term(s) Aged ; Female ; Humans ; Breast/pathology ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Breast Neoplasms/radiotherapy ; Breast Neoplasms/surgery ; Mastectomy, Segmental/adverse effects ; Neoplasm Recurrence, Local/mortality ; Neoplasm Staging ; Radiotherapy, Adjuvant ; Withholding Treatment ; Survival Analysis
    Language English
    Publishing date 2023-03-03
    Publishing country United States
    Document type Clinical Trial, Phase III ; Journal Article ; Randomized Controlled Trial
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMoa2207586
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Longitudinal predictors of children's self-blame appraisals among military families reported for family violence.

    Rancher, Caitlin / Hanson, Rochelle / Williams, Linda M / Saunders, Benjamin E / Smith, Daniel W

    Child abuse & neglect

    2023  Volume 147, Page(s) 106596

    Abstract: Background: Although children's self-blame appraisals are recognized as important sequelae of child victimization that contribute to subsequent adjustment problems, little is known about the factors that predict their development and longitudinal course. ...

    Abstract Background: Although children's self-blame appraisals are recognized as important sequelae of child victimization that contribute to subsequent adjustment problems, little is known about the factors that predict their development and longitudinal course.
    Objective: The current study examines the stability and longitudinal predictors of children's self-blame appraisals among a sample of children reported for family violence.
    Participants and setting: Children (N = 195; 63 % female) aged 7 to 17 years (M
    Methods: Children completed assessments on self-blame at 3 time points (baseline, 9-12 months, and 18-24 months) and baseline measures of their victimization experience, caregiver-child conflict, and depression.
    Results: In univariate analyses, victimization that involved injury (r = 0.29, p < .001), the number of perpetrators (r = 0.23, p = .001), the number of victimization types (r = 0.32, p < .001), caregiver-child conflict (r = 0.36, p < .001), and depression (r = 0.39, p < .001) were each positively associated with baseline self-blame. When examined in a single longitudinal multilevel model, results indicated only caregiver-child conflict (b = 0.08, p = .007) and baseline depression (b = 0.06, p = .013) predicted increases in self-blame.
    Conclusion: Findings suggest clinicians and researchers may consider assessment of victimization characteristics, caregiver-child relationships, and depression symptoms to identify children most at risk for developing self-blame appraisals.
    MeSH term(s) Humans ; Female ; United States/epidemiology ; Male ; Family Conflict ; Military Family ; Domestic Violence ; Crime Victims ; Sex Offenses
    Language English
    Publishing date 2023-12-09
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 799143-5
    ISSN 1873-7757 ; 0145-2134
    ISSN (online) 1873-7757
    ISSN 0145-2134
    DOI 10.1016/j.chiabu.2023.106596
    Database MEDical Literature Analysis and Retrieval System OnLINE

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