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  1. Book: The Art and Science of Aging Well

    Williams M. D., Mark E.

    A Physician's Guide to a Healthy Body, Mind, and Spirit

    2022  

    Author's details Mark E. Williams, M.D., is clinical professor of medicine at the University of North Carolina, with an active clinical practice in Wilmington, North Carolina
    Language English
    Size 242 p.
    Publisher The University of North Carolina Press
    Document type Book
    Note PDA Manuell_15
    Format 156 x 234 x 14
    ISBN 9781469669335 ; 1469669331
    Database PDA

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  2. Article ; Online: Antimicrobial activity of cuprous oxide-coated and cupric oxide-coated surfaces.

    Behzadinasab, S / Hosseini, M / Williams, M D / Ivester, H M / Allen, I C / Falkinham, J O / Ducker, W A

    The Journal of hospital infection

    2022  Volume 129, Page(s) 58–64

    Abstract: Background: Disease can be spread through contact with contaminated surfaces (fomites). For example, fomites have been implicated in the spread of meticillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Antimicrobial surface ... ...

    Abstract Background: Disease can be spread through contact with contaminated surfaces (fomites). For example, fomites have been implicated in the spread of meticillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Antimicrobial surface treatments are a potential method of reducing disease transmission from fomites, and broad-spectrum activity is desirable.
    Aim: To test cuprous oxide (Cu
    Methods: We fabricated two surface coatings. The Cu
    Findings: The coatings rapidly killed nine different micro-organisms, including Gram-negative and Gram-positive bacteria, mycobacteria and fungi. For example, the Cu
    Conclusion: The combination of broad-spectrum antimicrobial activity, abrasion resistance, and low toxicity of the Cu
    MeSH term(s) Humans ; Copper/pharmacology ; Staphylococcus aureus ; Methicillin-Resistant Staphylococcus aureus ; Polyurethanes ; Methicillin ; Pseudomonas aeruginosa ; Anti-Bacterial Agents ; Anti-Infective Agents/pharmacology ; Oxides
    Chemical Substances cuprous oxide (T8BEA5064F) ; cupric oxide (V1XJQ704R4) ; Copper (789U1901C5) ; Polyurethanes ; Methicillin (Q91FH1328A) ; Anti-Bacterial Agents ; Anti-Infective Agents ; Oxides
    Language English
    Publishing date 2022-08-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 779366-2
    ISSN 1532-2939 ; 0195-6701
    ISSN (online) 1532-2939
    ISSN 0195-6701
    DOI 10.1016/j.jhin.2022.07.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Top 50 Most-Cited Studies about Osteochondritis Dissecans

    Nicholas D. Thomas, M.S. / Raegan Mahler, B.S. / Kylie Krombholz, B.S. / Brendan Williams, M.D. / Ted Ganley, M.D. / Jeffrey J. Nepple, M.D. / Kevin Shea, M.D.

    Arthroscopy, Sports Medicine, and Rehabilitation, Vol 6, Iss 1, Pp 100859- (2024)

    2024  

    Abstract: Purpose: To determine the 50 most frequently cited studies on osteochondritis dissecans (OCD) and to conduct a bibliometric analysis of these studies. Methods: We performed a search within the Clarivate Web of Science database, identifying articles ... ...

    Abstract Purpose: To determine the 50 most frequently cited studies on osteochondritis dissecans (OCD) and to conduct a bibliometric analysis of these studies. Methods: We performed a search within the Clarivate Web of Science database, identifying articles published before December 2022 that encompass topics related to OCD. The search was conducted using the keywords “Osteochondritis Dissecans OR Osteochondritis OR Dissecans.”Search results were then filtered using predetermined guidelines and criteria, and the 50 most-cited articles were selected for analysis. Extracted data included title, journal, design, main topic, joint, citations, year, country of origin, and level of evidence. Results: The search yielded 3,865 articles. The 50 most-cited articles were published between 1957 and 2018, with the greatest proportion published from 2000 to 2009 (60%). The most frequently studied topic was treatment (68%), followed by etiology (14%) and imaging (8%). The majority of articles had Level IV evidence (36%) and the largest proportion focused on the knee joint (36%), followed by the ankle (32%), and elbow (6%). The mean citation count per article was 287 (range: 157-1,050), with the most-cited articles primarily published from 2000 to 2003. The leading country of origin was the United States, accounting for 19 publications. Conclusions: Most of the top 50 most-cited articles regarding OCD are about treatment, and the knee is the most-studied joint. The majority of the articles were Level IV evidence and were published in the United States between 2000 and 2009. Clinical Relevance: The top 50 most-cited studies list will provide researchers, medical students, residents, and fellows with a foundational list of the most important and influential academic contributions regarding osteochondritis dissecans (OCD).
    Keywords Sports medicine ; RC1200-1245
    Subject code 001
    Language English
    Publishing date 2024-02-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: The effect of Nordic hamstring exercise training volume on biceps femoris long head architectural adaptation.

    Presland, J D / Timmins, R G / Bourne, M N / Williams, M D / Opar, D A

    Scandinavian journal of medicine & science in sports

    2018  Volume 28, Issue 7, Page(s) 1775–1783

    Abstract: The aim of this study was to determine the time course of architectural adaptations in the biceps femoris long head ( ... ...

    Abstract The aim of this study was to determine the time course of architectural adaptations in the biceps femoris long head (BF
    MeSH term(s) Adaptation, Physiological ; Adult ; Exercise ; Hamstring Muscles/physiology ; Humans ; Male ; Muscle Strength ; Physical Conditioning, Human/methods ; Young Adult
    Language English
    Publishing date 2018-05-08
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1077418-x
    ISSN 1600-0838 ; 0905-7188
    ISSN (online) 1600-0838
    ISSN 0905-7188
    DOI 10.1111/sms.13085
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Analysing factors affecting the choice of emergent human resource capital

    Irani, S / Dwivedi, Y. K / Williams, M. D

    Journal of the Operational Research Society : OR Vol. 65, No. 6 , p. 935-953

    2014  Volume 65, Issue 6, Page(s) 935–953

    Author's details S. Irani, Y. K. Dwivedi and M. D. Williams
    Keywords higher education ; modelling scenarios ; international student choice ; decision-making process ; strategic planning ; OR techniques
    Language English
    Size graph. Darst.
    Publisher Palgrave
    Publishing place Basingstoke, Hampshire
    Document type Article
    ZDB-ID 716033-1 ; 2069025-3
    ISSN 0030-3623 ; 1473-2858 ; 1473-284X
    ISSN 0030-3623 ; 1473-2858 ; 1473-284X
    Database ECONomics Information System

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  6. Article: Ultrasound-guided botulinum toxin injection to treat a parotid fistula following gunshot injury.

    Gok, Gulcan / Michl, P / Williams, M D / Howlett, D C

    Journal of the Royal Army Medical Corps

    2015  Volume 161, Issue 1, Page(s) 64–66

    Abstract: Parotid fistula is a rare but very distressing sequelum of post-operative or traumatic injuries. The management of these injuries has been reported in the literature previously and techniques employed include pressure dressings, surgery and more recently ...

    Abstract Parotid fistula is a rare but very distressing sequelum of post-operative or traumatic injuries. The management of these injuries has been reported in the literature previously and techniques employed include pressure dressings, surgery and more recently botulinum toxin A (BTA) injections. We present a patient who developed a parotid fistula as a late complication of an extensive gunshot injury to the face with subsequent successful management with ultrasound-guided intraglandular injections of BTA. This case demonstrates that the BTA injection is an effective and safe method under ultrasound guidance and should considered as a first-line treatment option for the treatment of salivary fistulas.
    MeSH term(s) Botulinum Toxins, Type A/therapeutic use ; Facial Injuries/complications ; Facial Injuries/surgery ; Fistula/diagnostic imaging ; Fistula/drug therapy ; Fistula/etiology ; Humans ; Male ; Middle Aged ; Neurotoxins/therapeutic use ; Parotid Gland/diagnostic imaging ; Ultrasonography, Interventional ; Wounds, Gunshot/complications ; Wounds, Gunshot/surgery
    Chemical Substances Neurotoxins ; Botulinum Toxins, Type A (EC 3.4.24.69)
    Language English
    Publishing date 2015-03
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 840678-9
    ISSN 2052-0468 ; 0035-8665
    ISSN (online) 2052-0468
    ISSN 0035-8665
    DOI 10.1136/jramc-2013-000188
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Muscle activation patterns in the Nordic hamstring exercise: Impact of prior strain injury.

    Bourne, M N / Opar, D A / Williams, M D / Al Najjar, A / Shield, A J

    Scandinavian journal of medicine & science in sports

    2016  Volume 26, Issue 6, Page(s) 666–674

    Abstract: This study aimed to determine: (a) the spatial patterns of hamstring activation during the Nordic hamstring exercise (NHE); (b) whether previously injured hamstrings display activation deficits during the NHE; and (c) whether previously injured ... ...

    Abstract This study aimed to determine: (a) the spatial patterns of hamstring activation during the Nordic hamstring exercise (NHE); (b) whether previously injured hamstrings display activation deficits during the NHE; and (c) whether previously injured hamstrings exhibit altered cross-sectional area (CSA). Ten healthy, recreationally active men with a history of unilateral hamstring strain injury underwent functional magnetic resonance imaging of their thighs before and after six sets of 10 repetitions of the NHE. Transverse (T2) relaxation times of all hamstring muscles [biceps femoris long head (BFlh); biceps femoris short head (BFsh); semitendinosus (ST); semimembranosus (SM)] were measured at rest and immediately after the NHE and CSA was measured at rest. For the uninjured limb, the ST's percentage increase in T2 with exercise was 16.8%, 15.8%, and 20.2% greater than the increases exhibited by the BFlh, BFsh, and SM, respectively (P < 0.002 for all). Previously injured hamstring muscles (n = 10) displayed significantly smaller increases in T2 post-exercise than the homonymous muscles in the uninjured contralateral limb (mean difference -7.2%, P = 0.001). No muscles displayed significant between-limb differences in CSA. During the NHE, the ST is preferentially activated and previously injured hamstring muscles display chronic activation deficits compared with uninjured contralateral muscles.
    MeSH term(s) Adolescent ; Adult ; Cross-Sectional Studies ; Exercise/physiology ; Exercise Test ; Hamstring Muscles/diagnostic imaging ; Hamstring Muscles/injuries ; Hamstring Muscles/pathology ; Hamstring Muscles/physiopathology ; Humans ; Magnetic Resonance Imaging ; Male ; Muscle Contraction ; Muscle Relaxation ; Organ Size ; Sprains and Strains/physiopathology ; Young Adult
    Language English
    Publishing date 2016-06
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1077418-x
    ISSN 1600-0838 ; 0905-7188
    ISSN (online) 1600-0838
    ISSN 0905-7188
    DOI 10.1111/sms.12494
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Central Nervous System and Head and Neck Histiocytoses: A Comprehensive Review on the Spectrum of Imaging Findings.

    Hashmi, S S / Guha-Thakurta, N / Ketonen, L / Williams, M D / Shah, S / Debnam, J M

    Neurographics (2011)

    2018  Volume 6, Issue 2, Page(s) 114–122

    Abstract: The histiocytoses are a rare group of varied but related disorders characterized by abnormal tissue proliferation of macrophages and dendritic cells within tissues. The purpose of this article was to review the imaging findings in patients presenting ... ...

    Abstract The histiocytoses are a rare group of varied but related disorders characterized by abnormal tissue proliferation of macrophages and dendritic cells within tissues. The purpose of this article was to review the imaging findings in patients presenting with CNS and with head and neck manifestations of these disorders. Histiocytoses include but are not limited to Rosai-Dorfman disease, Erdheim Chester disease, Langerhans cell histiocytosis, histiocytic sarcoma, and juvenile xanthogranuloma. A review of the literature was performed to determine the sites of disease involvement. This article includes the demographics, histopathologic criteria for diagnosis, and imaging features of these histiocytoses, and describes the manifestations in locations known to harbor disease: intraaxial and extra-axial intracranial regions, the calvaria, skull base, hypothalamopituitary axis, orbits, paranasal sinuses, spine, and the head and neck region. Histiocytoses have variable imaging appearances in the CNS and in the head and neck region, and radiologists should be aware of the spectrum of findings to avoid mistaking them for other disease processes.
    Learning objective: To understand the general pathophysiology, clinical presentation, and typical imaging characteristics of the most common histiocytoses; comprehend the morphologic and immunohistochemical characteristics of these histiocytoses and the hallmark findings on pathology; and be able to differentiate between these disorders based on their most common presentations.
    Language English
    Publishing date 2018-10-25
    Publishing country United States
    Document type Journal Article
    ISSN 2637-8329
    ISSN (online) 2637-8329
    DOI 10.3174/ng.2160150
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: How phenotype guides management of the neuroendocrine carcinomas of the larynx.

    López, F / Hunt, J L / Nixon, I J / Rinaldo, A / Williams, M D / Cardesa, A / Ferlito, A

    The Journal of laryngology and otology

    2018  Volume 132, Issue 7, Page(s) 568–574

    Abstract: Objective: This review aimed to critically analyse data pertaining to the clinical presentation and treatment of neuroendocrine carcinomas of the larynx.: Method: A PubMed search was performed using the term 'neuroendocrine carcinoma'. English- ... ...

    Abstract Objective: This review aimed to critically analyse data pertaining to the clinical presentation and treatment of neuroendocrine carcinomas of the larynx.
    Method: A PubMed search was performed using the term 'neuroendocrine carcinoma'. English-language articles on neuroendocrine carcinoma of the larynx were reviewed in detail.Results and conclusionWhile many historical classifications have been proposed, in contemporary practice these tumours are sub-classified into four subtypes: carcinoid, atypical carcinoid, small cell neuroendocrine carcinoma and large cell neuroendocrine carcinoma. These tumours exhibit a wide range of biological behaviour, ranging from the extremely aggressive nature of small and large cell neuroendocrine carcinomas, which usually have a fatal prognosis, to the less aggressive course of carcinoid tumours. In small and large cell neuroendocrine carcinomas, a combination of irradiation and chemotherapy is indicated, while carcinoid and atypical carcinoid tumour management entails conservation surgery.
    MeSH term(s) Antineoplastic Protocols ; Carcinoid Tumor/genetics ; Carcinoid Tumor/pathology ; Carcinoid Tumor/therapy ; Carcinoma, Neuroendocrine/genetics ; Carcinoma, Neuroendocrine/pathology ; Carcinoma, Neuroendocrine/therapy ; Carcinoma, Small Cell/genetics ; Carcinoma, Small Cell/pathology ; Carcinoma, Small Cell/therapy ; Conservative Treatment/methods ; Humans ; Laryngeal Neoplasms/genetics ; Laryngeal Neoplasms/pathology ; Laryngeal Neoplasms/therapy ; Larynx/pathology ; Larynx/surgery ; Phenotype ; Prognosis
    Language English
    Publishing date 2018-07
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 218299-3
    ISSN 1748-5460 ; 0022-2151
    ISSN (online) 1748-5460
    ISSN 0022-2151
    DOI 10.1017/S0022215118000968
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Membrane bioreactor process for removing biodegradable organic matter from water

    Williams, M.D / Pirbazari, M

    Water research. 2007 Sept., v. 41, issue 17

    2007  

    Keywords bioreactors ; organic matter ; biodegradability ; artificial membranes ; drinking water ; water treatment ; water quality ; ozonation ; powders ; activated carbon ; biomass ; dissolved organic carbon ; adsorption ; biodegradation ; carbon ; aldehydes ; disinfection ; microbial growth ; filtration ; fouling ; membrane permeability ; Aquaspirillum ; Pseudomonas fluorescens ; microbial detection ; particulates ; hydraulic systems ; California
    Language English
    Dates of publication 2007-09
    Size p. 3880-3893.
    Document type Article
    Note In the special issue: Memebranes / edited by D. Dixon, S. Gray and B. Jefferson.
    ZDB-ID 202613-2
    ISSN 1879-2448 ; 0043-1354
    ISSN (online) 1879-2448
    ISSN 0043-1354
    DOI 10.1016/j.watres.2007.06.010
    Database NAL-Catalogue (AGRICOLA)

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