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  1. Article: Alzheimer Disease: A Life-Limiting Disease With a Burden of a Terminal Illness.

    Waziry, Reem / Williams, Olajide A

    Neurology. Clinical practice

    2023  Volume 13, Issue 6, Page(s) e200208

    Abstract: Purpose of review: An estimated 6.5 million Americans live with Alzheimer dementia. Better understanding of advanced stages of Alzheimer disease (AD) and timely monitoring of its preventable complications would translate to improved survival and quality ...

    Abstract Purpose of review: An estimated 6.5 million Americans live with Alzheimer dementia. Better understanding of advanced stages of Alzheimer disease (AD) and timely monitoring of its preventable complications would translate to improved survival and quality of life in this population.
    Recent findings: In this perspective review, we proposed shifting the narrative to recognizing AD as a chronic life-limiting illness instead of a terminal disease. In support of this view, we discussed the following: (1) the biochemical, cellular (preclinical), and clinical phases of AD; (2) survival after AD; (3) AD therapeutics and potential implications for the population with AD in the advanced stages.
    Summary: On the bases of the prolonged preclinical phase in AD, promising advances in AD therapeutics and the varying survival after AD, we proposed a new classification for AD and more broadly neurodegenerative disorders to be recognized as chronic
    Language English
    Publishing date 2023-10-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2645818-4
    ISSN 2163-0933 ; 2163-0402
    ISSN (online) 2163-0933
    ISSN 2163-0402
    DOI 10.1212/CPJ.0000000000200208
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Development and Validation of a Stroke Literacy Assessment Test for Community Health Workers.

    Mallaiah, Janhavi / Williams, Olajide / Allegrante, John P

    Health education & behavior : the official publication of the Society for Public Health Education

    2024  , Page(s) 10901981241245050

    Abstract: Community health workers (CHWs) are increasingly being required to perform complex health care activities, especially in community cardiovascular disease and stroke prevention. However, currently, there are no psychometrically validated instruments for ... ...

    Abstract Community health workers (CHWs) are increasingly being required to perform complex health care activities, especially in community cardiovascular disease and stroke prevention. However, currently, there are no psychometrically validated instruments for assessing CHW competencies in these roles. This article describes the development and validation of the stroke literacy assessment test (SLAT)-pertaining to the Life's Simple Seven (LS7) risk factors for stroke-for evaluating CHWs' competencies in the context of education and training programs. The SLAT was developed using an iterative instrument design protocol, followed by empirically testing the instrument in 68 CHWs from the Columbia University Institute for Training Outreach and Community Health (InTOuCH) in New York. Data collection began in March 2021 and continued through May 2021. The evaluation was based on four types of validity evidence: (a) content validation with expert reviews of items and overall domain, (b) validation on examinee response processes with cognitive interviews, (c) item validation and diagnostic analysis, and (d) validity evidence based on expected directional group differences. In addition, the internal consistency reliability of the total test scores, with the best functioning items, were evaluated. Two such iterative cycles yielded a 34-item, written structured response test that assesses the
    Language English
    Publishing date 2024-04-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1362906-2
    ISSN 1552-6127 ; 1090-1981
    ISSN (online) 1552-6127
    ISSN 1090-1981
    DOI 10.1177/10901981241245050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Going the Extra Mile: Disparities in Access to Specialized Stroke Care.

    Mullen, Michael T / Williams, Olajide A

    Stroke

    2021  Volume 52, Issue 8, Page(s) 2580–2582

    MeSH term(s) Humans ; Stroke/epidemiology ; Stroke/therapy
    Language English
    Publishing date 2021-06-10
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.121.035128
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: "The Design and Acceptability of a Hip Hop Themed Integrated Nutrition Math Curriculum for Minoritized 5th Grade Students Using the Multisensory Multilevel Health Education Model".

    Swierad, Ewelina M / Rausch, John C / Sawyer, Vanessa / Drucker, Gabriela / Williams, Olajide

    Health promotion practice

    2024  , Page(s) 15248399241240431

    Abstract: Digital technology creates new opportunities to design multisensory learning experiences. Evidence suggests that digital innovation can greatly benefit health education, including nutrition programs. The COVID-19 pandemic disrupted the education sector, ... ...

    Abstract Digital technology creates new opportunities to design multisensory learning experiences. Evidence suggests that digital innovation can greatly benefit health education, including nutrition programs. The COVID-19 pandemic disrupted the education sector, forcing schools to modify standard practices from exclusively in-person delivery to online or blended learning. Digitalized curriculums became particularly useful as an Emergency Remote Teaching tool. This article focuses on developing and implementing a multimedia, multisensory, and scalable Hip-Hop Healthy Eating and Living in Schools (H.E.A.L.S.) Nutrition-Math Curriculum (NMC). NMC comprises 20 lessons-music-based multimedia resources used in the classroom or at home. Fourteen lessons represent self-directed online modules (asynchronous learning) hosted on a Learning Management System (LMS) called "Gooru." The remaining six lessons are teacher-facilitated (in person or using Zoom) review sessions (synchronous learning). The article discusses (1) the development of NMC through the lens of the Multisensory Multilevel Health Education Model (MMHEM), (2) the high acceptability of NMC evaluated using a mixed-methods design among minoritized fifth-grade students attending an after-school program, and (3) the students' completion and mastery rates of the NMC modules based on LMS data. Multimedia nutrition education programs integrated with common core curriculum content, such as NMC, may be a promising avenue for disseminating health education to minoritized children living in New York City and similar high fast-food density cities.
    Language English
    Publishing date 2024-03-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2036801-X
    ISSN 1552-6372 ; 1524-8399
    ISSN (online) 1552-6372
    ISSN 1524-8399
    DOI 10.1177/15248399241240431
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Measures of Aging Biology in Saliva and Blood as Novel Biomarkers for Stroke and Heart Disease in Older Adults.

    Waziry, Reem / Gu, Yian / Boehme, Amelia K / Williams, Olajide A

    Neurology

    2023  Volume 101, Issue 23, Page(s) e2355–e2363

    Abstract: Background and objectives: The role of aging biology as a novel risk factor and biomarker for vascular outcomes in different accessible body tissues such as saliva and blood remain unclear. We aimed to (1) assess the role of aging biology as a risk ... ...

    Abstract Background and objectives: The role of aging biology as a novel risk factor and biomarker for vascular outcomes in different accessible body tissues such as saliva and blood remain unclear. We aimed to (1) assess the role of aging biology as a risk factor of stroke and heart disease among individuals of same chronologic age and sex and (2) compare aging biology biomarkers measured in different accessible body tissues as novel biomarkers for stroke and heart disease in older adults.
    Methods: This study included individuals who consented for blood and saliva draw in the Venous Blood Substudy and Telomere Length Study of the Health and Retirement Study (HRS). The HRS is a population-based, nationally representative longitudinal survey of individuals aged 50 years and older in the United States. Saliva-based measures included telomere length. Blood-based measures included DNA methylation and physiology biomarkers. Propensity scores-matched analyses and Cox regression models were conducted.
    Results: This study included individuals aged 50 years and older, who consented for blood (N = 9,934) and saliva (N = 5,808) draw in the HRS. Blood-based biomarkers of aging biology showed strong associations with incident stroke as follows: compared with the lowest tertile of blood-based biomarkers of aging, biologically older individuals had significantly higher risk of stroke based on DNA methylation Grim Age clock (adjusted hazard ratio [aHR] = 2.64, 95% CI 1.90-3.66,
    Discussion: Compared with saliva-based telomere length, blood-based aging physiology and some DNA methylation biomarkers are strongly associated with vascular disorders including stroke and are more precise and sensitive biomarkers of aging. Saliva-based telomere length and blood-based DNA methylation and physiology biomarkers likely represent different aspects of biological aging and accordingly vary in their precision as novel biomarkers for optimal vascular health.
    MeSH term(s) Humans ; United States ; Middle Aged ; Aged ; Saliva ; Aging ; Stroke/epidemiology ; Stroke/genetics ; Heart Diseases ; DNA Methylation ; Biomarkers ; Biology
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-12-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000207909
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Stroking Out While Black-The Complex Role of Racism.

    Williams, Olajide / Ovbiagele, Bruce

    JAMA neurology

    2020  Volume 77, Issue 11, Page(s) 1343–1344

    MeSH term(s) African Americans/ethnology ; Healthcare Disparities/ethnology ; Humans ; Racism/ethnology ; Self Concept ; Social Determinants of Health/ethnology ; Stroke/ethnology ; Stroke/mortality ; Stroke/therapy ; United States/ethnology
    Keywords covid19
    Language English
    Publishing date 2020-08-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2702023-X
    ISSN 2168-6157 ; 2168-6149
    ISSN (online) 2168-6157
    ISSN 2168-6149
    DOI 10.1001/jamaneurol.2020.3510
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Representation of Racial/ Ethnic Minority Individuals in the Leadership of Major Medical Journals.

    Rakhra, Ashlin / Ogedegbe, Gbenga / Williams, Olajide / Onakomaiya, Deborah / Ovbiagele, Bruce

    Journal of health disparities research and practice

    2022  Volume 14, Issue 4, Page(s) 69–81

    Abstract: Medical journals play an important role in achieving health equity by diversifying their leadership, but there is a dearth of published data on how they are faring. The objective of this study was to assess the proportions of the underrepresented in ... ...

    Abstract Medical journals play an important role in achieving health equity by diversifying their leadership, but there is a dearth of published data on how they are faring. The objective of this study was to assess the proportions of the underrepresented in medicine (UIM) racial/ ethnic minorities in medical journal leadership. We pre-selected 6 prominent general medicine journals, 9 prominent specialty journals, and 5 "control" journals (covering public health, health equity, and bench research), assembled names of all editors/ editorial board members listed on the website-based journal mastheads and used major public internet search engines to obtain information about sex, race, and ethnicity. We searched the journal databases for all articles published on racial/ethnic disparities or health equity by each journal between January 2015 to October 2020. Among general medicine journals, there were no UIM Editors-in-Chief or Deputy Editors; 1 (2%) Black and 3 (5%) Hispanic among Associate Editors (n=65); and 8 (6%) Black, and 2 (2%) Hispanic among Editorial Board Members (n=136). Among specialty journals, there were no UIM Editors-in-Chief; 3 (7%) Black and 0 (0%) Hispanic Deputy or Associate Editors (n=43); 6 (6%) Black and 5 (5%) Hispanic Editorial Board Members (n=105). Among "control" journals, there were Black Editors-in-Chief, but no Hispanic Editors-in-chief; 7 (8%) Black and 1(1%) Hispanic Deputy and Associate editors (n=86); 43 (47%) Black and 3 (3%) Hispanic Editorial Board Members (n=92). There is considerable room for improvement to enhance the involvement of UIM racial/ethnic minority individuals in leadership of prominent general and specialty medical journals.
    Language English
    Publishing date 2022-04-18
    Publishing country United States
    Document type Journal Article
    ISSN 2166-5222
    ISSN 2166-5222
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Cardiovascular Disease and Stroke-Focused Competency Assessment Tools for Community Health Workers in the United States: A Scoping Review.

    Mallaiah, Janhavi / Leon, Reynaldo De / Williams, Olajide / Allegrante, John P

    Health promotion practice

    2022  Volume 24, Issue 6, Page(s) 1183–1195

    Abstract: Cardiovascular disease (CVD) and stroke are major contributors to chronic disease burden in the United States. Despite the high prevalence of stroke, 90% of all stroke events are preventable and can be attributed to seven key modifiable risk factors ( ... ...

    Abstract Cardiovascular disease (CVD) and stroke are major contributors to chronic disease burden in the United States. Despite the high prevalence of stroke, 90% of all stroke events are preventable and can be attributed to seven key modifiable risk factors (MRFs)-high blood pressure (BP), high cholesterol, diabetes mellitus (DM), smoking, obesity, unhealthy diet, and physical inactivity. In the United States, stroke prevention interventions led by community health workers (CHWs) have been proven to be highly effective in preventing the onset of MRFs. We conducted a scoping review of the competency assessment methods used in CVD and stroke-focused CHW training programs. We searched six online databases: PubMed, Cochrane, CINAHL, Embase, Web of Science, and HaPI, from all available years until January 2021. Of the 1,774 initial articles found, we identified 30 eligible articles to be included in the review. Nine of these studies used previously validated instruments, whereas the remaining 21 studies used tools from the training curriculum or independently developed instruments. Only five of these validated tools reported psychometric properties; none of them were designed for the CHW population. Our scoping review of literature revealed that CHW-specific competency assessment methods were limited, with few or no domain-referenced tools on CVD or stroke risk factors that complied with established measurement standards. We conclude that there is an urgent need for the development of a comprehensive and valid assessment instrument in CVD and stroke prevention to evaluate CHW performance and optimize their credibility, representing important first steps toward integrating CHWs into health care systems.
    MeSH term(s) Humans ; United States ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/prevention & control ; Community Health Workers/education ; Hypertension ; Delivery of Health Care ; Risk Factors
    Language English
    Publishing date 2022-09-05
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 2036801-X
    ISSN 1552-6372 ; 1524-8399
    ISSN (online) 1552-6372
    ISSN 1524-8399
    DOI 10.1177/15248399221120809
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A Multisensory Multilevel Health Education Model for Diverse Communities.

    Williams, Olajide / Swierad, Ewelina M

    International journal of environmental research and public health

    2019  Volume 16, Issue 5

    Abstract: Owing to their enormous capacity to improve health and save lives, effective health promotion frameworks have been at the forefront of public health research and practice. A multilevel focus, as exemplified by the Socio-Ecological Model (SEM), is one ... ...

    Abstract Owing to their enormous capacity to improve health and save lives, effective health promotion frameworks have been at the forefront of public health research and practice. A multilevel focus, as exemplified by the Socio-Ecological Model (SEM), is one common denominator among these frameworks. The SEM highlights important social and ecological influences on health behavior by delineating the different levels of influence. These include public policy, organizational, community, interpersonal, and intrapersonal levels, which, when considered during the development of health promotion campaigns, especially those that focus on health education, strengthen the potential influence of that campaign on targeted behaviors. However, the SEM lacks a complimenting framework for understanding the role of conventional and unconventional approaches to health education; that is, how to design a health education intervention that considers both the context, such as the social and ecological levels of influence, and the best approaches for developing and delivering the health education in a manner that optimizes their effectiveness in today's modern and increasingly diverse world. Addressing this gap, the current article presents an integrative Multisensory Multilevel Health Education Model (MMHEM), which incorporates three key domains-(1) Art (innovativeness/creativity), (2) Culture (cultural tailoring), and (3) Science (evidence-based), while promoting the importance of considering the socio-ecological levels of influence on targeted behaviors. Using a successful health education intervention, called the Hip Hop Stroke, we deconstruct the Multisensory Multilevel Health Education Model and discuss its potential role as a guide for developing public health education interventions.
    MeSH term(s) Health Education/methods ; Models, Theoretical ; Multilevel Analysis ; Public Health/methods ; Public Policy
    Language English
    Publishing date 2019-03-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph16050872
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Letter by Willey and Williams Regarding Article, "Racial and Ethnic Disparities in the Utilization of Thrombectomy for Acute Stroke: Analysis of Data From 2016 to 2018".

    Willey, Joshua Z / Williams, Olajide

    Stroke

    2019  Volume 50, Issue 11, Page(s) e339

    MeSH term(s) Continental Population Groups ; Ethnic Groups ; Humans ; Stroke ; Thrombectomy
    Language English
    Publishing date 2019-10-14
    Publishing country United States
    Document type Letter ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.119.027577
    Database MEDical Literature Analysis and Retrieval System OnLINE

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