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Article ; Online: Atrial Fibrillation and Worse Outcomes in ST-Segment-Elevation Myocardial Infarction: Is It All About Infarct Size, or Do We Need to Look Elsewhere?

Suksaranjit, Promporn / Wilson, Brent D

2018 Volume 11, Issue 2, Page(s) e007472

MeSH term(s)	Atrial Fibrillation ; Humans ; Percutaneous Coronary Intervention ; Prognosis ; ST Elevation Myocardial Infarction
Language	English
Publishing date	2018-02-02
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	2435045-X
ISSN	1942-0080 ; 1941-9651
ISSN (online)	1942-0080
ISSN	1941-9651
DOI	10.1161/CIRCIMAGING.118.007472
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Zs.A 6743: Show issues

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Article ; Online: Improved Thrombus Assessment by Transesophageal Echocardiography: The DOLOP (Detection of Left Atrial Appendage Thrombosis Utilizing Optison) Study.

Catino, Anna B / Ross, Alexander / Suksaranjit, Promporn / Wilson, Brent D

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

2021 Volume 34, Issue 8, Page(s) 916–917

MeSH term(s)	Albumins ; Atrial Appendage/diagnostic imaging ; Atrial Fibrillation ; Echocardiography, Transesophageal ; Fluorocarbons ; Heart Diseases ; Humans ; Thrombosis/diagnosis
Chemical Substances	Albumins ; FS 069 ; Fluorocarbons
Language	English
Publishing date	2021-04-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	1035622-8
ISSN	1097-6795 ; 0894-7317
ISSN (online)	1097-6795
ISSN	0894-7317
DOI	10.1016/j.echo.2021.03.012
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Zs.A 2638: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MG 55: Show issues

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Article ; Online: Cardiac Amyloidosis and Electrical Cardioversion: Is the Thrombus There or Not?

Csecs, Ibolya / Merkely, Bela / Wilson, Brent D

Journal of the American College of Cardiology

2019 Volume 73, Issue 22, Page(s) 2909–2910

MeSH term(s)	Adult ; Amyloidosis ; Atrial Fibrillation ; Electric Countershock ; Humans ; Thrombosis
Language	English
Publishing date	2019-06-06
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	605507-2
ISSN	1558-3597 ; 0735-1097
ISSN (online)	1558-3597
ISSN	0735-1097
DOI	10.1016/j.jacc.2019.03.491
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Zs.A 1846: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 196: Show issues

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Article ; Online: Left atrial fibrosis provides a new means of identifying patients with higher risk of new-onset heart failure among patients with atrial fibrillation.

Azadani, Peyman N / Marrouche, Nassir F / Wilson, Brent D

International journal of cardiology

2018 Volume 257, Page(s) 113–114

MeSH term(s)	Atrial Appendage ; Atrial Fibrillation ; Fibrosis ; Heart Atria ; Heart Failure ; Humans
Language	English
Publishing date	2018--15
Publishing country	Netherlands
Document type	Letter ; Comment
ZDB-ID	779519-1
ISSN	1874-1754 ; 0167-5273
ISSN (online)	1874-1754
ISSN	0167-5273
DOI	10.1016/j.ijcard.2017.12.081
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Zs.A 1673: Show issues

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Article ; Online: Atrioesophageal fistula and pneumocephalus after pulmonary vein isolation.

Wilson, Brent D / Morshedzadeh, Jack H

European heart journal cardiovascular Imaging

2015 Volume 16, Issue 7, Page(s) 819

MeSH term(s)	Aged, 80 and over ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/surgery ; Catheter Ablation/adverse effects ; Catheter Ablation/methods ; Disease Progression ; Esophageal Fistula/diagnostic imaging ; Esophageal Fistula/etiology ; Fatal Outcome ; Heart Atria/pathology ; Hemiplegia/diagnosis ; Hemiplegia/etiology ; Humans ; Male ; Pneumocephalus/diagnostic imaging ; Pneumocephalus/etiology ; Pulmonary Veins/surgery ; Seizures/diagnosis ; Seizures/etiology ; Tomography, X-Ray Computed
Language	English
Publishing date	2015-07
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2638345-7
ISSN	2047-2412 ; 2047-2404
ISSN (online)	2047-2412
ISSN	2047-2404
DOI	10.1093/ehjci/jev089
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Zs.A 5614: Show issues

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Article ; Online: Accelerated cardiac T1 mapping with recurrent networks and cyclic, model-based loss.

Le, Johnathan V / Mendes, Jason K / McKibben, Nicholas / Wilson, Brent D / Ibrahim, Mark / DiBella, Edward V R / Adluru, Ganesh

Medical physics

2022 Volume 49, Issue 11, Page(s) 6986–7000

Abstract: Background: Using the spin-lattice relaxation time (T1) as a biomarker, the myocardium can be quantitatively characterized using cardiac T1 mapping. The modified Look-Locker inversion (MOLLI) recovery sequences have become the standard clinical method ... ...

Abstract	Background: Using the spin-lattice relaxation time (T1) as a biomarker, the myocardium can be quantitatively characterized using cardiac T1 mapping. The modified Look-Locker inversion (MOLLI) recovery sequences have become the standard clinical method for cardiac T1 mapping. However, the MOLLI sequences require an 11-heartbeat breath-hold that can be difficult for subjects, particularly during exercise or pharmacologically induced stress. Although shorter cardiac T1 mapping sequences have been proposed, these methods suffer from reduced precision. As such, there is an unmet need for accelerated cardiac T1 mapping. Purpose: To accelerate cardiac T1 mapping MOLLI sequences by using neural networks to estimate T1 maps using a reduced number of T1-weighted images and their corresponding inversion times. Materials and methods: In this retrospective study, 911 pre-contrast T1 mapping datasets from 202 subjects (128 males, 56 ± 15 years; 74 females, 54 ± 17 years) and 574 T1 mapping post-contrast datasets from 193 subjects (122 males, 57 ± 15 years; 71 females, 54 ± 17 years) were acquired using the MOLLI-5(3)3 sequence and the MOLLI-4(1)3(1)2 sequence, respectively. All acquisition protocols used similar scan parameters: Results: Our proposed network demonstrated similar T1 estimations to the standard MOLLI sequences (pre-contrast: Conclusions: A bidirectional multilayered LSTM network with fully connected output and cyclic model-based loss was used to generate high-quality pre- and post-contrast T1 maps using the first three T1-weighted images and their corresponding inversion times. This work demonstrates that combining deep learning with cardiac T1 mapping can potentially accelerate standard MOLLI sequences from 11 to 3 heartbeats.
MeSH term(s)	Male ; Female ; Humans ; Heart/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Retrospective Studies ; Reproducibility of Results ; Myocardium ; Phantoms, Imaging
Chemical Substances	gadoteridol (0199MV609F)
Language	English
Publishing date	2022-06-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	188780-4
ISSN	2473-4209 ; 0094-2405
ISSN (online)	2473-4209
ISSN	0094-2405
DOI	10.1002/mp.15801
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Zs.A 1210: Show issues

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Article ; Online: Atrial fibrosis in embolic stroke of undetermined source: A multicenter study.

Kühnlein, Peter / Mahnkopf, Christian / Majersik, Jennifer J / Wilson, Brent D / Mitlacher, Marcel / Tirschwell, David / Longstreth, W T / Akoum, Nazem

European journal of neurology

2021 Volume 28, Issue 11, Page(s) 3634–3639

Abstract: Background and purpose: Left atrial (LA) cardiac disease is a suspected cause of embolic stroke of undetermined source (ESUS). We tested the hypothesis that LA fibrosis, quantified using late-gadolinium-enhancement magnetic resonance imaging (LGE-MRI), ... ...

Abstract	Background and purpose: Left atrial (LA) cardiac disease is a suspected cause of embolic stroke of undetermined source (ESUS). We tested the hypothesis that LA fibrosis, quantified using late-gadolinium-enhancement magnetic resonance imaging (LGE-MRI), predicts recurrent stroke or atrial fibrillation (AF) in patients with ESUS. Methods: We compared atrial fibrosis in healthy controls and patients with lacunar stroke, ESUS, and known AF with or without prior stroke. We followed patients with ESUS prospectively for the primary outcome of recurrent ischemic stroke, incident AF, or both. Results: We enrolled 203 patients from three centers: 103 patients without AF (35 healthy controls, 15 with lacunar strokes, 53 with ESUS) and 100 patients with AF (50 with and 50 without prior stroke). Patients with ESUS had significantly higher atrial fibrosis (15.0 ± 6.2%) compared to healthy controls (8.1 ± 7.9%; <0.0001) and compared to lacunar stroke patients (10.8 ± 8.4; p = 0.02), but had comparable fibrosis to patients with AF with (17.9 ± 11.4%) or without prior stroke (16.6 ± 9.2%; p = NS for both). Over a mean follow-up of 19 months, nine of 53 patients (16.9%) with ESUS experienced the combined primary outcome, which included six patients (11.3%) with recurrent ischemic stroke and five patients with incident AF (9.4%). Patients with ESUS with fibrosis ≥12% had a higher proportion of the combined outcome: 25.0% vs. 4.8%; p = 0.039. Conclusions: Patients with ESUS demonstrate atrial fibrosis comparable to that seen in AF. Atrial fibrosis ≥12% was associated with recurrent stroke, incident AF or both. This subgroup of ESUS patients may benefit from anticoagulation for secondary prevention of ischemic stroke.
MeSH term(s)	Atrial Fibrillation/complications ; Embolic Stroke ; Fibrosis ; Humans ; Intracranial Embolism/complications ; Intracranial Embolism/diagnostic imaging ; Magnetic Resonance Imaging ; Risk Factors ; Stroke/complications ; Stroke/diagnostic imaging
Language	English
Publishing date	2021-07-24
Publishing country	England
Document type	Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
ZDB-ID	1280785-0
ISSN	1468-1331 ; 1351-5101 ; 1471-0552
ISSN (online)	1468-1331
ISSN	1351-5101 ; 1471-0552
DOI	10.1111/ene.15022
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Zs.A 4738: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 592: Show issues

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Article ; Online: Exploring the role of aldosterone in right ventricular function.

Harrison, Alexis / Wilson, Brent D / Ryan, John J

The Canadian journal of cardiology

2014 Volume 30, Issue 2, Page(s) 155–158

MeSH term(s)	Aldosterone/blood ; Blood Pressure/physiology ; Female ; Heart Ventricles/physiopathology ; Humans ; Hypertension/complications ; Male ; Renin/blood ; Renin-Angiotensin System/physiology ; Ventricular Dysfunction, Right/etiology
Chemical Substances	Aldosterone (4964P6T9RB) ; Renin (EC 3.4.23.15)
Language	English
Publishing date	2014-02
Publishing country	England
Document type	Comment ; Editorial
ZDB-ID	632813-1
ISSN	1916-7075 ; 0828-282X
ISSN (online)	1916-7075
ISSN	0828-282X
DOI	10.1016/j.cjca.2013.12.025
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Zs.A 2150: Show issues

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Article ; Online: Late Gadolinium Enhancement Magnetic Resonance Imaging Evaluation of Post-Atrial Fibrillation Ablation Esophageal Thermal Injury Across the Spectrum of Severity.

Marashly, Qussay / Gopinath, Chaitra / Baher, Alex / Acharya, Madan / Kheirkhahan, Mobin / Hardisty, Benjamin / Aljuaid, Mossab / Tawhari, Ibrahim / Ibrahim, Mark / Morris, Alan K / Kholmovski, Eugene G / Wilson, Brent D / Marrouche, Nassir F / Chelu, Mihail G

Journal of the American Heart Association

2021 Volume 10, Issue 7, Page(s) e018924

Abstract: Background Esophageal thermal injury (ETI) is a byproduct of atrial fibrillation (AF) ablation using thermal sources. The most severe form of ETI is represented by atrioesophageal fistula, which has a high mortality rate. Late gadolinium enhancement (LGE) ...

Abstract	Background Esophageal thermal injury (ETI) is a byproduct of atrial fibrillation (AF) ablation using thermal sources. The most severe form of ETI is represented by atrioesophageal fistula, which has a high mortality rate. Late gadolinium enhancement (LGE) magnetic resonance imaging (MRI) allows identification of ETI. Hence, we sought to evaluate the utility of LGE-MRI as a method to identify ETI across the entire spectrum of severity. Methods and Results All AF radiofrequency ablations performed at the University of Utah between January 2009 and December 2017 were reviewed. Patients with LGE-MRI within 24 hours following AF ablation as well as patients who had esophagogastroduodenoscopy in addition to LGE-MRI were identified. An additional patient with atrioesophageal fistula who had AF ablation at a different institution and had MRI and esophagogastroduodenoscopy at the University of Utah was identified. A total of 1269 AF radiofrequency ablations were identified. ETI severity was classified on the basis of esophageal LGE pattern (none, 60.9%; mild, 27.5%; moderate, 9.9%; severe, 1.7%). ETI resolved in most patients who underwent repeat LGE-MRI at 3 months. All patients with esophagogastroduodenoscopy-confirmed ETI had moderate-to-severe LGE 24 hours after ablation MRI. Moderate-to-severe LGE had 100% sensitivity and 58.1% specificity in detecting ETI, and a negative predictive value of 100%. Atrioesophageal fistula was visualized by both computed tomography and LGE-MRI in one patient. Conclusions LGE-MRI is useful in detecting and characterizing ETI across the entire severity spectrum. LGE-MRI exhibits an extremely high sensitivity and negative predictive value in screening for ETI after AF ablation.
MeSH term(s)	Aged ; Atrial Fibrillation/surgery ; Burns/diagnosis ; Burns/etiology ; Catheter Ablation/adverse effects ; Contrast Media/pharmacology ; Esophagoscopy/methods ; Esophagus/diagnostic imaging ; Esophagus/injuries ; Female ; Follow-Up Studies ; Gadolinium/pharmacology ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Retrospective Studies ; Severity of Illness Index ; Time Factors
Chemical Substances	Contrast Media ; Gadolinium (AU0V1LM3JT)
Language	English
Publishing date	2021-03-24
Publishing country	England
Document type	Journal Article ; Observational Study
ZDB-ID	2653953-6
ISSN	2047-9980 ; 2047-9980
ISSN (online)	2047-9980
ISSN	2047-9980
DOI	10.1161/JAHA.120.018924
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Article ; Online: Saturation recovery-prepared magnetic resonance angiography for assessment of left atrial and esophageal anatomy.

Siebermair, Johannes / Kholmovski, Eugene G / Sheffer, Douglas / Schroeder, Joyce / Jensen, Leif / Kheirkhahan, Mobin / Baher, Alex A / Ibrahim, Majd M / Reiter, Theresa / Rassaf, Tienush / Wakili, Reza / Marrouche, Nassir F / McGann, Christopher J / Wilson, Brent D

The British journal of radiology

2021 Volume 94, Issue 1123, Page(s) 20210048

Abstract: Objectives: Magnetic resonance angiography (MRA) has been established as an important imaging method in cardiac ablation procedures. In pulmonary vein (PV) isolation procedures, MRA has the potential to minimize the risk of severe complications, such as ...

Abstract	Objectives: Magnetic resonance angiography (MRA) has been established as an important imaging method in cardiac ablation procedures. In pulmonary vein (PV) isolation procedures, MRA has the potential to minimize the risk of severe complications, such as atrio-esophageal fistula, by providing detailed information on esophageal position relatively to cardiac structures. However, traditional non-gated, first-pass (FP) MRA approaches have several limitations, such as long breath-holds, non-uniform signal intensity throughout the left atrium (LA), and poor esophageal visualization. The aim of this observational study was to validate a respiratory-navigated, ECG-gated (EC), saturation recovery-prepared MRA technique for simultaneous imaging of LA, LA appendage, PVs, esophagus, and adjacent anatomical structures. Methods: Before PVI, 106 consecutive patients with a history of AF underwent either conventional FP-MRA ( Results: EC-MRA demonstrated significantly better image quality than FP-MRA in every quality category. Esophageal visibility using the new MRA technique was markedly better than with the conventional FP-MRA technique (median 3.5 [IQR 1] Conclusion: Our ECG-gated, respiratory-navigated, saturation recovery-prepared MRA technique provides significantly better image quality and esophageal visibility than the established non-gated, breath-holding FP-MRA. Image quality of EC-MRA technique has the additional advantage of being unaffected by heart rate. Advances in knowledge: Detailed information of cardiac anatomy has the potential to minimize the risk of severe complications and improve success rates in invasive electrophysiological studies. Our novel ECG-gated, respiratory-navigated, saturation recovery-prepared MRA technique provides significantly better image quality of LA and esophageal structures than the traditional first-pass algorithm. This new MRA technique is robust to arrhythmia (tachycardic, irregular heart rates) frequently observed in AF patients.
MeSH term(s)	Atrial Appendage/diagnostic imaging ; Atrial Fibrillation/diagnostic imaging ; Breath Holding ; Cardiac-Gated Imaging Techniques ; Contrast Media ; Esophagus/diagnostic imaging ; Female ; Heart Atria/diagnostic imaging ; Humans ; Magnetic Resonance Angiography/methods ; Male ; Meglumine/analogs & derivatives ; Middle Aged ; Organometallic Compounds ; Pulmonary Veins/diagnostic imaging ; Respiratory-Gated Imaging Techniques
Chemical Substances	Contrast Media ; Organometallic Compounds ; gadobenic acid (15G12L5X8K) ; Meglumine (6HG8UB2MUY)
Language	English
Publishing date	2021-06-11
Publishing country	England
Document type	Journal Article ; Observational Study ; Validation Study
ZDB-ID	2982-8
ISSN	1748-880X ; 0007-1285
ISSN (online)	1748-880X
ISSN	0007-1285
DOI	10.1259/bjr.20210048
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