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  1. Article: Municipal Contagious Disease Hospitals-Their Medical and Financial Importance to the Community.

    Wilson, R J

    Buffalo medical journal

    2023  Volume 64, Issue 4, Page(s) 195–203

    Language English
    Publishing date 2023-03-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 426473-3
    ISSN 1040-3817
    ISSN 1040-3817
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Shades of grey: embracing uncertainty in the exercise room.

    Wilson, R J T

    British journal of anaesthesia

    2018  Volume 120, Issue 6, Page(s) 1145–1146

    MeSH term(s) Color ; Exercise ; Exercise Test ; Uncertainty
    Language English
    Publishing date 2018-04-22
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2018.03.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Oesophageal Doppler monitoring - the emperor's new clothes?

    Wilson, R J T

    Anaesthesia

    2013  Volume 68, Issue 10, Page(s) 1072–1073

    MeSH term(s) Esophagus/diagnostic imaging ; Esophagus/physiology ; Evidence-Based Medicine ; Humans ; Monitoring, Intraoperative/methods ; Therapeutic Equipoise ; Ultrasonography
    Language English
    Publishing date 2013-10
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.12405
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: THE PART PLAYED BY HOSPITALS IN THE CONTROL OF CONTAGIOUS DISEASES.

    Wilson, R J

    American journal of public health (New York, N.Y. : 1912)

    2007  Volume 6, Issue 3, Page(s) 261–264

    Language English
    Publishing date 2007-10-25
    Publishing country United States
    Document type Journal Article
    ISSN 0271-4353
    ISSN 0271-4353
    DOI 10.2105/ajph.6.3.261
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Penicillin in Subacute Bacterial Endocarditis.

    Smyth, B T / Wilson, R J

    The Ulster medical journal

    2010  Volume 15, Issue 1, Page(s) 29–41

    Language English
    Publishing date 2010-04-05
    Publishing country Northern Ireland
    Document type Journal Article
    ZDB-ID 603342-8
    ISSN 2046-4207 ; 0041-6193
    ISSN (online) 2046-4207
    ISSN 0041-6193
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Parasite plastids: approaching the endgame.

    Wilson, R J M Iain

    Biological reviews of the Cambridge Philosophical Society

    2005  Volume 80, Issue 1, Page(s) 129–153

    Abstract: Considerable work still needs to be done to understand more fully the basic processes going on inside the non-photosynthetic plastid organelle of Plasmodium spp., the causative agent of malaria. Following an explosion of genomic and transcriptional ... ...

    Abstract Considerable work still needs to be done to understand more fully the basic processes going on inside the non-photosynthetic plastid organelle of Plasmodium spp., the causative agent of malaria. Following an explosion of genomic and transcriptional information in recent years, research workers are still analysing these data looking for new material relevant to the plastid. Several metabolic and housekeeping functions based on bacterial biochemistry have been elucidated and this has given impetus to finding lead inhibitors based on established anti-microbials. Structural investigations of plastid-associated enzymes identified as potential targets have begun. This review gives a perspective on the research to date and hopes to emphasize that a practical outcome for the clinic should be an important focus of future efforts. Malaria parasites have become resistant to front-line anti-malarials that are widely used and were formerly dependable. This has become a worrying problem in many regions where malaria is endemic. The time lag between hunting for new inhibitors and their application as pharmaceuticals is so long and costly that a steady stream of new ventures has to be undertaken to give a reasonable chance of finding affordable and appropriate anti-malarials for the future. Attempts to find inhibitors of the plastid organelle of the malaria parasite should be intensified in such programmes.
    MeSH term(s) Animals ; Antimalarials/pharmacology ; Biological Evolution ; Genome, Protozoan ; Humans ; Intracellular Membranes/metabolism ; Malaria/drug therapy ; Malaria/metabolism ; Malaria/prevention & control ; Organelles/metabolism ; Parasitic Sensitivity Tests ; Phylogeny ; Plasmodium/classification ; Plasmodium/drug effects ; Plasmodium/metabolism ; Plasmodium/ultrastructure ; Plastids/metabolism
    Chemical Substances Antimalarials
    Language English
    Publishing date 2005-02-21
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1476789-2
    ISSN 1469-185X ; 1464-7931 ; 0006-3231
    ISSN (online) 1469-185X
    ISSN 1464-7931 ; 0006-3231
    DOI 10.1017/s1464793104006591
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Closed Fluxtubes and Dispersive Proton Conics at Jupiter's Polar Cap.

    Szalay, J R / Clark, G / Livadiotis, G / McComas, D J / Mitchell, D G / Rankin, J S / Sulaiman, A H / Allegrini, F / Bagenal, F / Ebert, R W / Gladstone, G R / Kurth, W S / Mauk, B H / Valek, P W / Wilson, R J / Bolton, S J

    Geophysical research letters

    2022  Volume 49, Issue 9, Page(s) e2022GL098741

    Abstract: Two distinct proton populations are observed over Jupiter's southern polar cap: a ∼1 keV core population and ∼1-300 keV dispersive conic population at 6-7 ... ...

    Abstract Two distinct proton populations are observed over Jupiter's southern polar cap: a ∼1 keV core population and ∼1-300 keV dispersive conic population at 6-7 R
    Language English
    Publishing date 2022-04-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 7403-2
    ISSN 0094-8276
    ISSN 0094-8276
    DOI 10.1029/2022GL098741
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Water-Group Pickup Ions From Europa-Genic Neutrals Orbiting Jupiter.

    Szalay, J R / Smith, H T / Zirnstein, E J / McComas, D J / Begley, L J / Bagenal, F / Delamere, P A / Wilson, R J / Valek, P W / Poppe, A R / Nénon, Q / Allegrini, F / Ebert, R W / Bolton, S J

    Geophysical research letters

    2022  Volume 49, Issue 9, Page(s) e2022GL098111

    Abstract: Water-group gas continuously escapes from Jupiter's icy moons to form co-orbiting populations of particles or neutral toroidal clouds. These clouds provide insights into their source moons as they reveal loss processes and compositions of their parent ... ...

    Abstract Water-group gas continuously escapes from Jupiter's icy moons to form co-orbiting populations of particles or neutral toroidal clouds. These clouds provide insights into their source moons as they reveal loss processes and compositions of their parent bodies, alter local plasma composition, and act as sources and sinks for magnetospheric particles. We report the first observations of H
    Language English
    Publishing date 2022-05-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 7403-2
    ISSN 0094-8276
    ISSN 0094-8276
    DOI 10.1029/2022GL098111
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Prognostic Markers of Outcome in Patients Undergoing Infra-inguinal Revascularisation: A Prospective Observational Pilot Study.

    Kanakaraj, M / Yates, D R / Wilson, R J T / Baroni, M L / Davies, S J

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2017  Volume 54, Issue 2, Page(s) 212–219

    Abstract: Objectives: The aim was to investigate whether cardiopulmonary exercise testing (CPET) variables derived from cycle and arm ergonometry correlate, and whether CPET variables and pre-operative N-terminal pro-brain natriuretic peptide (NT-proBNP) have ... ...

    Abstract Objectives: The aim was to investigate whether cardiopulmonary exercise testing (CPET) variables derived from cycle and arm ergonometry correlate, and whether CPET variables and pre-operative N-terminal pro-brain natriuretic peptide (NT-proBNP) have prognostic significance and if the combination of the two has incremental value.
    Methods: A prospective observational pilot study was conducted; 70 patients who underwent infra-inguinal bypass surgery were recruited. Pre-operatively subjects underwent CPET with both arm and leg ergonometry, to measure peak oxygen consumption, anaerobic threshold (AT), and ventilatory equivalents. In addition pre-operative serum samples of NT-proBNP were obtained. The primary endpoint was 1 year all-cause mortality; in addition, data were collected on complications, morbidity, length of stay, and major adverse cardiac events (MACE).
    Results: The 1 year mortality rate was 6%, the overall complications rate was 23%, and the combined incidence of MACE and 1 year mortality was 10%. Cycle ergonometry peak VO
    Conclusion: The measurement of pre-operative NT-proBNP in peripheral vascular disease patients undergoing infra-inguinal bypass can predict 1 year mortality and MACE. CPET variables from cycle ergonometry are predictors of post-operative complications in this patient group.
    Language English
    Publishing date 2017-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2017.05.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: A randomised trial of non-invasive cardiac output monitoring to guide haemodynamic optimisation in high risk patients undergoing urgent surgical repair of proximal femoral fractures (ClearNOF trial NCT02382185).

    Davies, S J / Yates, D R / Wilson, R J T / Murphy, Z / Gibson, A / Allgar, V / Collyer, T

    Perioperative medicine (London, England)

    2019  Volume 8, Page(s) 8

    Abstract: Background: Hip fracture is a procedure with high mortality and complication rates, and there exists a group especially at risk of these outcomes identified by their Nottingham Hip Fracture Score (NHFS). Meta-analysis suggests a possible benefit to this ...

    Abstract Background: Hip fracture is a procedure with high mortality and complication rates, and there exists a group especially at risk of these outcomes identified by their Nottingham Hip Fracture Score (NHFS). Meta-analysis suggests a possible benefit to this patient group from intravascular volume optimisation. We investigated whether intraoperative fluid and blood pressure optimisation improved complications in this group.
    Methods: Patients with a NHFS ≥ 5 were enrolled into this multicentre observer-blinded randomised control trial. Patients were allocated to either standard care or a combination of fluid optimisation and blood pressure control using a non-invasive system. The primary outcome was the number of patients with one or more complications in each group. Secondary outcomes included hospital length of stay (LOS), incidence of hypotension and fluid and vasopressor usage.
    Results: Forty-six percent of patients in the intervention group suffered one or more complications compared to the 51% in the control group (OR 0.82 (95% CI 0.49-1.36)). Per-protocol analysis improved the OR to 0.73 (95% CI 0.43-1.24). Median LOS was the same between both groups; however, the mean LOS on a per-protocol analysis was longer in the control group compared to the intervention group (23.2 (18.0) days vs. 18.5 (16.5),
    Conclusions: Haemodynamic optimisation including blood pressure management in high-risk patients undergoing repair of a hip fracture did not result in a statistically significant reduction in complications; however, a potential reduction in length of stay was seen.
    Trial registration: A randomised trial of non-invasive cardiac output monitoring to guide haemodynamic optimisation in high risk patients undergoing urgent surgical repair of proximal femoral fractures (ClearNOF trial NCT02382185).
    Language English
    Publishing date 2019-08-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2683800-X
    ISSN 2047-0525
    ISSN 2047-0525
    DOI 10.1186/s13741-019-0119-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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