Artikel ; Online: Outbreak of Klebsiella pneumoniae carbapenemase-producing K pneumoniae: A systematic review.
American journal of infection control
2016 Band 44, Heft 11, Seite(n) 1374–1380
Abstract: Background: First detected in the United States in 1996, Klebsiella pneumoniae carbapenemase (KPC) has spread internationally among gram-negative bacteria, especially K pneumoniae. These microorganisms can cause serious infections in hospitalized ... ...
| Abstract | Background: First detected in the United States in 1996, Klebsiella pneumoniae carbapenemase (KPC) has spread internationally among gram-negative bacteria, especially K pneumoniae. These microorganisms can cause serious infections in hospitalized patients, and there are few therapeutic options, culminating in increased mortality. The objective of this study was to describe the occurrence of outbreaks that were caused by KPC-producing K pneumoniae, emphasizing the interventions that were implemented to contain the outbreaks. Methods: PubMed, Web of Knowledge, and Literatura Latino Americana em Ciências da Saúde databases were searched for articles that were published between 2001 and 2012 according to the recommendations of Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Results: Of the 586 studies identified, 13 were selected for the final sample. Most studies showed that the containment of KPC outbreaks is possible in hospital settings through several actions, particularly use of surveillance cultures and the establishment of contact precautions. Conclusions: The results show that limiting the cross-transmission of these and other KPC-producing bacteria is possible in a hospital setting. However, such isolates need to be detected early with the aid of culture surveillance and contained early using appropriate actions immediately to prevent an outbreak. |
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| Mesh-Begriff(e) | Bacterial Proteins/secretion ; Cross Infection/epidemiology ; Cross Infection/microbiology ; Cross Infection/prevention & control ; Disease Outbreaks ; Disease Transmission, Infectious/prevention & control ; Global Health ; Humans ; Infection Control/methods ; Klebsiella Infections/epidemiology ; Klebsiella Infections/microbiology ; Klebsiella Infections/prevention & control ; Klebsiella pneumoniae/enzymology ; Klebsiella pneumoniae/isolation & purification ; beta-Lactamases/secretion | |||||
| Chemische Substanzen | Bacterial Proteins ; beta-Lactamases (EC 3.5.2.6) ; carbapenemase (EC 3.5.2.6) | |||||
| Sprache | Englisch | |||||
| Erscheinungsdatum | 2016-05-05 | |||||
| Erscheinungsland | United States | |||||
| Dokumenttyp | Journal Article ; Review | |||||
| ZDB-ID | 392362-9 | |||||
| ISSN | 1527-3296 ; 0196-6553 | |||||
| ISSN (online) | 1527-3296 | |||||
| ISSN | 0196-6553 | |||||
| DOI | 10.1016/j.ajic.2016.03.022 | |||||
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| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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