Article: Impact of choice of skin preparation solution in cardiac surgery on rate of surgical site infection: a propensity score matched analysis.
Journal of infection prevention
2017 Volume 19, Issue 1, Page(s) 16–21
Abstract: Background: Antiseptic skin preparations containing chlorhexidine gluconate and povidone iodine are routinely used to reduce the risk of surgical site infection (SSI). This study assesses the efficacy of two alcohol-based solutions, 2% chlorhexidine- ... ...
| Abstract | Background: Antiseptic skin preparations containing chlorhexidine gluconate and povidone iodine are routinely used to reduce the risk of surgical site infection (SSI). This study assesses the efficacy of two alcohol-based solutions, 2% chlorhexidine-alcohol and 10% povidone iodine-alcohol, on the incidence of cardiac SSI. Methods: A total of 738 consecutive patients undergoing cardiac surgery had skin preparation with 2% chlorhexidine gluconate in 70% isopropanol (ChloraPrep, BD Ltd, UK) were propensity matched to 738 patients with skin prepared with 10% povidone-iodine in 30% industrial methylated spirit (Videne Alcoholic Tincture, Ecolab Ltd, UK). Continuous, prospective SSI surveillance data were collected for all these patients. A retrospective analysis of prospectively collected perioperative data was performed. Results: The overall rate of SSI was similar in the chlorhexidine-alcohol and povidone-iodine-alcohol groups (3.3% versus 3.8%; Conclusion: Our analysis confirms that alcohol-based skin preparation in cardiac surgery with povidone-iodine reduces the incidence of organ-space infections with no significant superiority in preventing incisional SSI compared with chlorhexidine-alcohol. |
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| Language | English |
| Publishing date | 2017-08-08 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 2595000-9 |
| ISSN | 1757-1782 ; 1757-1774 |
| ISSN (online) | 1757-1782 |
| ISSN | 1757-1774 |
| DOI | 10.1177/1757177417722045 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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