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Article ; Online: Are relative educational inequalities in multiple health behaviors widening? A longitudinal study of middle-aged adults in Northern Norway.

Ibarra-Sanchez, Ana Silvia / Chen, Gang / Wisløff, Torbjørn

2023 Volume 11, Page(s) 1190087

Abstract: Introduction: Educational inequality in multiple health behaviors is rarely monitored using data from the same individuals as they age. The aim of this study is to research changes in relative educational inequality in multiple variables related to ... ...

Abstract	Introduction: Educational inequality in multiple health behaviors is rarely monitored using data from the same individuals as they age. The aim of this study is to research changes in relative educational inequality in multiple variables related to health behavior (smoking, physical activity, alcohol intake, and body mass index), separately and collectively (healthy lifestyle), among middle-aged adults living in Northern Norway. Methods: Data from adult respondents aged 32-87 in 2008 with repeated measurements in 2016 ( Results: Educational inequality was observed in all the variables related to health behavior at baseline and follow-up, in both men and women. Higher levels of educational attainment were associated with healthier categories (non-daily smoking, physical activity, normal body mass index, and a healthy lifestyle), but also with high alcohol intake. The prevalence of daily smoking and physical inactivity decreased during the surveyed period, while high alcohol intake, having a body mass index outside of the normal range and adhering to multiple health recommendations simultaneously increased. The magnitude of relative educational inequality measured at baseline increased at the follow-up in all the variables related to health behavior. Differences were larger among women when compared to men, except in physical inactivity. Conclusion: Persistent and increasing relative disparities in health behavior between the highest education level and lower education levels are found in countries with well-established and comprehensive welfare systems like Norway. Addressing these inequalities is essential for reducing both the chronic disease burden and educational disparities in health.
MeSH term(s)	Male ; Middle Aged ; Adult ; Female ; Humans ; Longitudinal Studies ; Educational Status ; Health Behavior ; Exercise ; Norway/epidemiology
Language	English
Publishing date	2023-08-22
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2023.1190087
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: [No title information]

Wisløff, Torbjørn

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

2017 Volume 137, Issue 7, Page(s) 518

Title translation	Ny norsk terskelverdi for verdien av et godt leveår?
MeSH term(s)	Cost-Benefit Analysis ; Health Priorities ; Humans ; Norway ; Quality-Adjusted Life Years
Language	Norwegian
Publishing date	2017-04
Publishing country	Norway
Document type	Journal Article
ZDB-ID	603504-8
ISSN	0807-7096 ; 0029-2001
ISSN (online)	0807-7096
ISSN	0029-2001
DOI	10.4045/tidsskr.17.0137
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Article ; Online: Educational patterns of health behaviors and body mass index: A longitudinal multiple correspondence analysis of a middle-aged general population, 2007-2016.

Ibarra-Sanchez, Ana Silvia / Abelsen, Birgit / Chen, Gang / Wisløff, Torbjørn

PloS one

2023 Volume 18, Issue 12, Page(s) e0295302

Abstract: Social differences in body mass index and health behaviors are a major public health challenge. The uneven distribution of unhealthy body mass index and of unhealthy behaviors such as smoking, physical inactivity, and harmful alcohol consumption has been ...

Abstract	Social differences in body mass index and health behaviors are a major public health challenge. The uneven distribution of unhealthy body mass index and of unhealthy behaviors such as smoking, physical inactivity, and harmful alcohol consumption has been shown to mediate social inequalities in chronic diseases. While differential exposures to these health variables have been investigated, the extent to which they vary over the lifetime in the same population and their relationship with level of education is not well understood. This study examines patterns of body mass index and multiple health behaviors (smoking, physical activity and alcohol consumption), and investigates their association with education level among adults living in Northern Norway. It presents findings from a longitudinal multiple correspondence analysis of the Tromsø Study. Longitudinal data from 8,906 adults aged 32-87 in 2007-2008, with repeated measurements in 2015-2016 were retrieved from the survey's sixth and seventh waves. The findings suggest that most in the study population remained in the same categories of body mass index and the three health behaviors at the follow-up, with a clear educational gradient in healthy patterns. That is, both healthy changes and maintained healthy categories were associated with the highest education levels. Estimating differential exposures to mediators of health inequalities could benefit policy priority setting for tackling inequalities in health.
MeSH term(s)	Adult ; Middle Aged ; Humans ; Body Mass Index ; Health Behavior ; Socioeconomic Factors ; Educational Status ; Exercise
Language	English
Publishing date	2023-12-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0295302
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Article ; Online: Priority-setting criteria in the Norwegian health services.

Wisløff, Torbjørn

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

2015 Volume 135, Issue 15, Page(s) 1373–1375

MeSH term(s)	Cost-Benefit Analysis ; Health Priorities/economics ; Health Priorities/organization & administration ; Humans ; Norway ; Severity of Illness Index
Language	Norwegian
Publishing date	2015-08-25
Publishing country	Norway
Document type	Journal Article
ZDB-ID	603504-8
ISSN	0807-7096 ; 0029-2001
ISSN (online)	0807-7096
ISSN	0029-2001
DOI	10.4045/tidsskr.15.0228
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Article ; Online: Comparing the sociodemographic characteristics of participants and non-participants in the population-based Tromsø Study.

Vo, Chi Quynh / Samuelsen, Per-Jostein / Sommerseth, Hilde Leikny / Wisløff, Torbjørn / Wilsgaard, Tom / Eggen, Anne Elise

BMC public health

2023 Volume 23, Issue 1, Page(s) 994

Abstract: Background: Differences in the sociodemographic characteristics of participants and non-participants in population-based studies may introduce bias and reduce the generalizability of research findings. This study aimed to compare the sociodemographic ... ...

Abstract	Background: Differences in the sociodemographic characteristics of participants and non-participants in population-based studies may introduce bias and reduce the generalizability of research findings. This study aimed to compare the sociodemographic characteristics of participants and non-participants of the seventh survey of the Tromsø Study (Tromsø7, 2015-16), a population-based health survey. Methods: A total of 32,591 individuals were invited to Tromsø7. We compared the sociodemographic characteristics of participants and non-participants by linking the Tromsø7 invitation file to Statistics Norway, and explored the association between these characteristics and participation using logistic regression. Furthermore, we created a geographical socioeconomic status (area SES) index (low-SES, medium-SES, and high-SES area) based on individual educational level, individual income, total household income, and residential ownership status. We then mapped the relationship between area SES and participation in Tromsø7. Results: Men, people aged 40-49 and 80-89 years, those who were unmarried, widowed, separated/divorced, born outside of Norway, had lower education, had lower income, were residential renters, and lived in a low-SES area had a lower probability of participation in Tromsø7. Conclusions: Sociodemographic differences in participation must be considered to avoid biased estimates in research based on population-based studies, especially when the relationship between SES and health is being explored. Particular attention should be paid to the recruitment of groups with lower SES to population-based studies.
MeSH term(s)	Male ; Humans ; Social Class ; Income ; Educational Status ; Health Surveys ; Surveys and Questionnaires ; Socioeconomic Factors
Language	English
Publishing date	2023-05-29
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2041338-5
ISSN	1471-2458 ; 1471-2458
ISSN (online)	1471-2458
ISSN	1471-2458
DOI	10.1186/s12889-023-15928-w
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Article ; Online: Perceived burden and need for support among caregivers of cancer patients.

Gjerset, Gunhild M / Kiserud, Cecilie E / Wisløff, Torbjørn / McCarthy, Jane B / Thorsen, Lene

Acta oncologica (Stockholm, Sweden)

2023 Volume 62, Issue 7, Page(s) 794–802

Abstract: Background: The aims of this study were to examine (1) the perceived burden among caregivers and identify those in risk of high burden and (2) the need for support among caregivers and identify associated factors.: Materials and methods: Cancer ... ...

Abstract	Background: The aims of this study were to examine (1) the perceived burden among caregivers and identify those in risk of high burden and (2) the need for support among caregivers and identify associated factors. Materials and methods: Cancer patients who participated in an educational program at the Montebello Center (MBC) in Norway between May 2021 and February 2022 were asked to invite a caregiver to answer a questionnaire. The caregiving burden was assessed with the Caregivers Reaction Assessment (CRA) that consists of 24 questions scored from 1 (strongly disagree) to 5 (strongly agree), covering five domains. A mean sum score was calculated for each domain. Higher subscale scores indicate higher levels of burden, except for caregiver esteem where a high score indicates a low burden. Need for support was assessed with 13 questions. Results: Of 464 invitations, 185 caregivers responded (response 40%), median age was 58.0 years and 58% were male. Caregiver burden mean scores were: 2.6 (SD 1.03) for Conclusions: The results indicate that caregivers of cancer patients participating at the MBC report moderate caregiver burden, however, numerous caregivers reported need for support within several areas. Our findings need to be confirmed in a larger unselected group.
MeSH term(s)	Humans ; Male ; Female ; Middle Aged ; Caregivers ; Neoplasms/therapy ; Comorbidity ; Surveys and Questionnaires ; Family Support ; Cost of Illness
Language	English
Publishing date	2023-08-04
Publishing country	England
Document type	Journal Article
ZDB-ID	896449-x
ISSN	1651-226X ; 0349-652X ; 0284-186X ; 1100-1704
ISSN (online)	1651-226X
ISSN	0349-652X ; 0284-186X ; 1100-1704
DOI	10.1080/0284186X.2023.2240008
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Article ; Online: Cost-effectiveness of antiplatelet drugs after percutaneous coronary intervention.

Wisløff, Torbjørn / Atar, Dan

European heart journal. Quality of care & clinical outcomes

2018 Volume 2, Issue 1, Page(s) 52–57

Abstract: Aims: Clopidogrel has, for long time, been accepted as the standard treatment for patients who have undergone a percutaneous coronary intervention (PCI). The introduction of prasugrel-and more recently, ticagrelor-has introduced a decision-making ... ...

Abstract	Aims: Clopidogrel has, for long time, been accepted as the standard treatment for patients who have undergone a percutaneous coronary intervention (PCI). The introduction of prasugrel-and more recently, ticagrelor-has introduced a decision-making problem for clinicians and governments worldwide: to use the cheaper clopidogrel or the more effective, and also more expensive prasugrel or ticagrelor. We aim to give helpful contributions to this debate by analysing the cost-effectiveness of clopidogrel, prasugrel, and ticagrelor compared with each other. Methods and results: We modified a previously developed Markov model of cardiac disease progression. In the model, we followed up cohorts of patients who have recently had a PCI until 100 years or death. Possible events are revascularization, bleeding, acute myocardial infarction, and death. Our analysis shows that ticagrelor is cost-effective in 77% of simulations at an incremental cost-effectiveness ratio of €7700 compared with clopidogrel. Ticagrelor was also cost-effective against prasugrel at a cost-effectiveness ratio of €7800. Given a Norwegian cost-effectiveness threshold of €70 000, both comparisons appear to be clearly cost-effective in favour of ticagrelor. Conclusion: Ticagrelor is cost-effective compared with both clopidogrel and prasugrel for patients who have undergone a PCI.
Language	English
Publishing date	2018-02-20
Publishing country	England
Document type	Journal Article
ZDB-ID	2823451-0
ISSN	2058-1742 ; 2058-5225
ISSN (online)	2058-1742
ISSN	2058-5225
DOI	10.1093/ehjqcco/qcv023
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Article ; Online: Clinical and economic impact of universal varicella vaccination in Norway: A modeling study.

Pawaskar, Manjiri / Burgess, Colleen / Pillsbury, Mathew / Wisløff, Torbjørn / Flem, Elmira

PloS one

2021 Volume 16, Issue 7, Page(s) e0254080

Abstract: Background: Norway has not implemented universal varicella vaccination, despite the considerable clinical and economic burden of varicella disease.: Methods: An existing dynamic transmission model of varicella infection was calibrated to age-specific ...

Abstract	Background: Norway has not implemented universal varicella vaccination, despite the considerable clinical and economic burden of varicella disease. Methods: An existing dynamic transmission model of varicella infection was calibrated to age-specific seroprevalence rates in Norway. Six two-dose vaccination strategies were considered, consisting of combinations of two formulations each of a monovalent varicella vaccine (Varivax® or Varilrix®) and a quadrivalent vaccine against measles-mumps-rubella-varicella (ProQuad® or PriorixTetra®), with the first dose given with a monovalent vaccine at age 15 months, and the second dose with either a monovalent or quadrivalent vaccine at either 18 months, 7 or 11 years. Costs were considered from the perspectives of both the health care system and society. Quality-adjusted life-years saved and incremental cost-effectiveness ratios relative to no vaccination were calculated. A one-way sensitivity analysis was conducted to assess the impact of vaccine efficacy, price, the costs of a lost workday and of inpatient and outpatient care, vaccination coverage, and discount rate. Results: In the absence of varicella vaccination, the annual incidence of natural varicella is estimated to be 1,359 per 100,000 population, and the cumulative numbers of varicella outpatient cases, hospitalizations, and deaths over 50 years are projected to be 1.81 million, 10,161, and 61, respectively. Universal varicella vaccination is projected to reduce the natural varicella incidence rate to 48-59 per 100,000 population, depending on the vaccination strategy, and to reduce varicella outpatient cases, hospitalizations, and deaths by 75-85%, 67-79%, and 75-79%, respectively. All strategies were cost-saving, with the most cost-saving as two doses of Varivax® at 15 months and 7 years (payer perspective) and two doses of Varivax® at 15 months and 18 months (societal perspective). Conclusions: All modeled two-dose varicella vaccination strategies are projected to lead to substantial reductions in varicella disease and to be cost saving compared to no vaccination in Norway.
MeSH term(s)	Chickenpox Vaccine/economics ; Chickenpox Vaccine/immunology ; Cost-Benefit Analysis ; Herpes Zoster/economics ; Herpes Zoster/epidemiology ; Herpes Zoster/immunology ; Herpes Zoster/mortality ; Hospitalization ; Humans ; Incidence ; Models, Immunological ; Norway/epidemiology ; Seroepidemiologic Studies ; Vaccination/economics
Chemical Substances	Chickenpox Vaccine
Language	English
Publishing date	2021-07-08
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0254080
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Article ; Online: Does Androgen Deprivation for Prostate Cancer Affect Normal Adaptation to Resistance Exercise?

Nilsen, Tormod S / Johansen, Sara Hassing / Thorsen, Lene / Fairman, Ciaran M / Wisløff, Torbjørn / Raastad, Truls

International journal of environmental research and public health

2022 Volume 19, Issue 7

Abstract: Background: Loss of muscle mass and muscle function is a common side effect from androgen deprivation therapy (ADT) for prostate cancer (PCa). Here, we explored effects of heavy-load resistance training (RT) on lean body mass and muscle strength changes ...

Abstract	Background: Loss of muscle mass and muscle function is a common side effect from androgen deprivation therapy (ADT) for prostate cancer (PCa). Here, we explored effects of heavy-load resistance training (RT) on lean body mass and muscle strength changes reported in randomized controlled trials (RCTs) among PCa patients on ADT and in healthy elderly men (HEM), by comparison of results in separate meta-analysis. Methods: RCTs were identified through databases and reference lists. Results: Seven RCTs in PCa patients ( Conclusions: The effects of RT on lean body mass and 1 RM were similar in PCa patients on ADT and HEM, but the mechanism for the intervention effect might differ between groups. It seems that RT counteracts loss of lean body mass during ADT in PCa patients, as opposed to increasing lean body mass in HEM.
MeSH term(s)	Adaptation, Physiological ; Aged ; Androgen Antagonists/therapeutic use ; Androgens/therapeutic use ; Humans ; Male ; Prostatic Neoplasms/chemically induced ; Resistance Training/methods
Chemical Substances	Androgen Antagonists ; Androgens
Language	English
Publishing date	2022-03-23
Publishing country	Switzerland
Document type	Journal Article ; Meta-Analysis ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph19073820
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Article ; Online: Validity of self-reported educational level in the Tromsø Study.

Vo, Chi Q / Samuelsen, Per-Jostein / Sommerseth, Hilde L / Wisløff, Torbjørn / Wilsgaard, Tom / Eggen, Anne E

Scandinavian journal of public health

2022 Volume 51, Issue 7, Page(s) 1061–1068

MeSH term(s)	Male ; Humans ; Female ; Adult ; Self Report ; Surveys and Questionnaires ; Educational Status ; Predictive Value of Tests ; Cardiovascular Diseases/epidemiology ; Norway
Language	English
Publishing date	2022-05-20
Publishing country	Sweden
Document type	Journal Article
ZDB-ID	1475054-5
ISSN	1651-1905 ; 1403-4948
ISSN (online)	1651-1905
ISSN	1403-4948
DOI	10.1177/14034948221088004
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