LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 229

Search options

  1. Article ; Online: Nucleon Sigma Terms with N_{f}=2+1 Flavors of O(a)-Improved Wilson Fermions.

    Agadjanov, A / Djukanovic, D / von Hippel, G / Meyer, H B / Ottnad, K / Wittig, H

    Physical review letters

    2024  Volume 131, Issue 26, Page(s) 261902

    Abstract: We present a lattice-QCD based analysis of the nucleon sigma terms using gauge ensembles with N_{f}=2+1 flavors of O(a)-improved Wilson fermions, with a complete error budget concerning excited-state contaminations, the chiral interpolation as well as ... ...

    Abstract We present a lattice-QCD based analysis of the nucleon sigma terms using gauge ensembles with N_{f}=2+1 flavors of O(a)-improved Wilson fermions, with a complete error budget concerning excited-state contaminations, the chiral interpolation as well as finite-size and lattice spacing effects. We compute the sigma terms determined directly from the matrix elements of the scalar currents. The chiral interpolation is based on SU(3) baryon chiral perturbation theory using the extended on-mass shell renormalization scheme. For the pion nucleon sigma term, we obtain σ_{πN}=(43.7±3.6)  MeV, where the error includes our estimate of the aforementioned systematics. The tension with extractions based on dispersion theory persists at the 2.4-σ level. For the strange sigma term, we obtain a nonzero value, σ_{s}=(28.6±9.3)  MeV.
    Language English
    Publishing date 2024-01-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.131.261902
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Book ; Thesis: D-Loop-BASE

    Wittig, Holger

    forensische Datenbank nichtcodierender mitochondrialer DNA-Sequenzen ; eine Analyse von 850 mtDNA-Sequenzen zentraleuropäischer Kaukasoider

    2000  

    Author's details vorgelegt von Holger Wittig
    Language German
    Size 65 Bl., graph. Darst., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Magdeburg, Univ., Diss., 2001
    HBZ-ID HT013192987
    Database Catalogue ZB MED Medicine, Health

    Kategorien

  3. Article ; Online: Fully automated radiologic identification focusing on the sternal bone.

    Neuhaus, Dominique / Wittig, Holger / Scheurer, Eva / Lenz, Claudia

    Forensic science international

    2023  Volume 346, Page(s) 111648

    Abstract: A crucial task in forensic investigations is the identification of unknown deceased. In general, secure identification methods rely on a comparison of ante mortem (AM) with post mortem (PM) data. However, available morphologic approaches are often ... ...

    Abstract A crucial task in forensic investigations is the identification of unknown deceased. In general, secure identification methods rely on a comparison of ante mortem (AM) with post mortem (PM) data. However, available morphologic approaches are often dependent on the expertise and experience of the examiner, and often lack standardisation and statistical evidence. The objective of this study was therefore to overcome the current challenges via developing a fully automated radiologic identification (autoRADid) method based on the sternal bone. An anonymised AM data set consisting of 91 chest computed tomography (CT) scans, as well as an anonymised PM data set of 42 chest CT scans were included in this work. Out of the 91 available AM CT data sets, 42 AM scans corresponded to the 42 PM CT scans. For the fully automated identification analysis, a custom-made python pipeline was developed, which automatically registers AM data to the PM data in question using a two-step registration method. To evaluate the registration procedure and subsequent identification success, the image similarity measures Jaccard Coefficient, Dice Coefficient, and Mutual Information were computed. The highest value for each metric was retrieved in order to analyse the correspondence between AM and PM data. For all three similarity measures, 38 out of the 42 cases were matched correctly. This corresponds to an accuracy of 91.2%. The four unsuccessful cases incorporated surgical interventions taking place between the AM and the PM CT acquisition or poor CT scan quality preventing robust registration results. To conclude, the presented autoRADid method seems to be a promising fully automated tool for a reliable and facile identification of unknown deceased. A final pipeline combining all three similarity measures is open source and publicly available for efficient future identifications of unknown deceased.
    MeSH term(s) Tomography, X-Ray Computed ; Sternum/diagnostic imaging ; Autopsy
    Language English
    Publishing date 2023-03-22
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 424042-x
    ISSN 1872-6283 ; 0379-0738
    ISSN (online) 1872-6283
    ISSN 0379-0738
    DOI 10.1016/j.forsciint.2023.111648
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Book ; Thesis: Proteinzusammensetzung des Parotisspeichels im Vergleich zu Schweiß, Urin und Serum bei Gesunden, Niereninsuffizienten und Dialysepatienten

    Wittig, Heike

    1992  

    Author's details eingereicht von: Heike Wittig
    Size 92 Bl. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dresden, Univ., Diss., 1993
    HBZ-ID HT004953905
    Database Catalogue ZB MED Medicine, Health

    Kategorien

  5. Article ; Online: Strange Electromagnetic Form Factors of the Nucleon with N_{f}=2+1 O(a)-Improved Wilson Fermions.

    Djukanovic, D / Ottnad, K / Wilhelm, J / Wittig, H

    Physical review letters

    2019  Volume 123, Issue 21, Page(s) 212001

    Abstract: We present results for the strange contribution to the electromagnetic form factors of the nucleon computed on the coordinated lattice simulation ensembles with N_{f}=2+1 flavors of O(a)-improved Wilson fermions and an O(a)-improved vector current. ... ...

    Abstract We present results for the strange contribution to the electromagnetic form factors of the nucleon computed on the coordinated lattice simulation ensembles with N_{f}=2+1 flavors of O(a)-improved Wilson fermions and an O(a)-improved vector current. Several source-sink separations are investigated in order to estimate the excited-state contamination. We calculate the form factors on six ensembles with lattice spacings in the range of a=0.049-0.086  fm and pion masses in the range of m_{π}=200-360  MeV, which allows for a controlled chiral and continuum extrapolation. In the computation of the quark-disconnected contributions, we employ hierarchical probing as a variance-reduction technique.
    Language English
    Publishing date 2019-12-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.123.212001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Book ; Thesis: Analyse der Entwicklung des Arzneimittelverbrauchs auf Wert- und Mengenbasis sowie der Therapie im Rahmen des Bekämpfungsmodells für chronische Herz-Kreislauf-Krankheiten in Schleiz an ausgewählten Arzneimitteln nach verschiedenen Methoden

    Wittig, Helmut

    1986  

    Size getr. Zählung : graph. Darst.
    Publishing country XA-DDDE
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Berlin, Humboldt-Univ., Diss., 1986
    HBZ-ID HT002912174
    Database Catalogue ZB MED Medicine, Health

    Kategorien

  7. Article: Investigation of post mortem brain, rectal and forehead temperature relations.

    Berger, Celine / Bauer, Melanie / Wittig, Holger / Gerlach, Kathrin / Scheurer, Eva / Lenz, Claudia

    Journal of thermal biology

    2023  Volume 115, Page(s) 103615

    Abstract: It is well known that magnetic resonance (MR) imaging is temperature sensitive, which is highly relevant for post mortem examinations. Therefore, the determination of the exact temperature of the investigated body site, e.g. the brain, is crucial. ... ...

    Abstract It is well known that magnetic resonance (MR) imaging is temperature sensitive, which is highly relevant for post mortem examinations. Therefore, the determination of the exact temperature of the investigated body site, e.g. the brain, is crucial. However, direct temperature measurements are invasive and inconvenient. Thus, in view of post mortem MR imaging of the brain, this study aims at investigating the relation between the brain and the forehead temperature for modelling the brain temperature based on the non-invasive forehead temperature. In addition, the brain temperature will be compared to the rectal temperature. Brain temperature profiles measured in the longitudinal fissure between the brain hemispheres, as well as rectal and forehead temperature profiles of 16 deceased were acquired continuously. Linear mixed, linear, quadratic and cubic models were fitted to the relation between the longitudinal fissure and the forehead and between the longitudinal fissure and the rectal temperature, respectively. Highest adjusted R
    MeSH term(s) Body Temperature ; Temperature ; Thermometers ; Forehead ; Autopsy ; Brain
    Language English
    Publishing date 2023-06-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 1498364-3
    ISSN 1879-0992 ; 0306-4565
    ISSN (online) 1879-0992
    ISSN 0306-4565
    DOI 10.1016/j.jtherbio.2023.103615
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Book ; Online: Essays on asset and portfolio management

    Wittig, Hagen

    rethinking portfolio rebalancing

    (Dissertationen / Universität St. Gallen ; No. 4432)

    2015  

    Abstract: Die vorliegende Dissertation beinhaltet drei Beiträge, welche sich mit verschiedenen Aspekten der Dynamischen Asset Allokation befassen. Letztere beschreibt die Steuerung der Portfolioallokation eines Investors im Verlauf der Investitionsphase angesichts ...

    Author's details submitted by Hagen Wittig (from Germany)
    Series title Dissertationen / Universität St. Gallen ; No. 4432
    Abstract Die vorliegende Dissertation beinhaltet drei Beiträge, welche sich mit verschiedenen Aspekten der Dynamischen Asset Allokation befassen. Letztere beschreibt die Steuerung der Portfolioallokation eines Investors im Verlauf der Investitionsphase angesichts eines sich wandelnden Marktumfeldes und dem Umgang mit mehreren Assetklassen mit unterschiedlichen Rendite-Risiko-Profilen. Im ersten Beitrag stellen wir eine Weiterentwicklung des traditionellen gewichtungsbasierten Rebalancingkonzepts vor, bei der die Bandbreiten nicht statisch, sondern in Abhängigkeit der aktuellen Marktbedingungen - in Form des relativen Preis- und Volatilitätsniveaus - gesetzt werden. Die empirische Analyse dieses Konzepts zeigt signifikante Überrenditen im Vergleich zu einer Buy and Hold Strategie, einer idealisierten SAA Strategie sowie einer ansonsten vergleichbaren Rebalancingstrategie mit statischen Bandbreiten. Die Charakteristiken des vorgeschlagenen Konzepts bleiben auch bei Anwendung auf verschiedene Subperioden erhalten. Im zweiten und dritten Beitrag beschreiten wir neue Wege auf dem Gebiet der Dynamischen Asset Allokation, indem wir explizit verschiedene Risikomasse in den Steuerungsprozess integrieren. Im zweiten Beitrag entwickeln wir ein Rebalancingkonzept, welches die Anteile der einzelnen Assetklassen an der Volatilität des Gesamtportfolios als Indikator für Portfolioreallokationen nutzt. Im Gegensatz zu traditionellen gewichtungsbasierten Rebalancingkonzepten ist dieser neue Ansatz in der Lage, Portfolioreallokationen aufgrund von Veränderungen der Volatilität einer einzelnen Assetklasse oder der Korrelationsstruktur einer Assetklasse zum Rest des Portfolios vorzunehmen. Dies ermöglicht es einem Investor, die Anteile der einzelnen Assetklassen an der Portfoliovolatilität während der gesamten Investitionsphase stabil zu halten. Im dritten Beitrag stellen wir ein weiteres Rebalancingkonzept vor, welches die Steuerung der Portfolioallokation basierend auf den Faktorladungen des Portfolios gegenüber den Risikofaktoren Zinssatz, Zinsstruktur, Kreditrisiko, Aktienprämie und Volatilität umsetzt. Um alle Faktorladungen werden entsprechende Bandbreiten implementiert, deren Verletzung Portfolioreallokationen auslöst, mit dem Ziel, die Faktorladungen wieder auf ihr strategisches Niveau zurückzuführen. Die empirische Analyse belegt, dass die Differenz der effektiven zu den strategischen Faktorladungen kleiner ausfällt als bei den analysierten Vergleichsstrategien.

    This dissertation comprises three articles which are covering various aspects in the area of dynamic asset allocation, i.e., how to control an investor's portfolio composition over time in light of changing market conditions and various asset classes with differing return and risk profiles. In the first article, we propose the advancement of the traditional value-based rebalancing framework by setting the bandwidth weights in a non-static manner depending on current market characteristics, namely the relative price and volatility levels. The empirical analysis reveals significant excess returns in comparison to a buy and hold strategy, an idealized SAA strategy, as well as a rebalancing strategy with static bandwidths but otherwise comparable characteristics. The proposed approach also proves to be robust in various subsamples. In the second and third article, we break new ground by explicitly incorporating the risk dimension in the dynamic asset allocation process. In the second article, we present a rebalancing approach which applies the various asset classes' risk contributions to control the rebalancing process during the investment period. In strong contrast to traditional value-based rebalancing strategies, the resulting risk contribution strategies are capable of triggering rebalancing procedures based on deviations in an asset class's stand-alone volatility or correlation to the portfolio's remaining asset classes. Thus, this method lets investors closely maintain the asset classes' initial risk contributions. In the third article, we develop another approach which applies the loadings of the investor's portfolio on various key risk factors as indicators for triggering the rebalancing process. We implement the approach by monitoring the loadings on the risk factors interest rate, term spread, credit risk, equity premium, and volatility. We further define bandwidths for every risk factor loading. Once the effective loading on a risk factor violates its bandwidth, asset reallocations are triggered in order to return the factor loadings to their strategic levels. The results of the empirical analysis prove that the effective loadings' deviation from the strategic loadings is much smaller for our approach than for the analyzed benchmark strategies. Thus, by implementing our approach, an investor will be able to generate more stable exposures towards key risk factors as compared to traditional value-based approaches.
    Keywords Kapitalanlage ; Kapitalmarktrendite ; Volatilität ; Portfolio-Management ; Theorie ; Asset management ; constant mix ; dynamic asset allocation ; portfolio allocation ; portfolio management ; rebalancing ; risk contributions ; risk factors
    Language English ; German
    Size 1 Online-Ressource (102 Seiten), Illustrationen
    Publishing place St. Gallen
    Document type Book ; Online
    Note Zusammenfassung in Deutsch und Englisch ; Enthält 3 Beiträge
    Database ECONomics Information System

    More links

    Kategorien

  9. Article ; Online: Weakly Bound H Dibaryon from SU(3)-Flavor-Symmetric QCD.

    Green, Jeremy R / Hanlon, Andrew D / Junnarkar, Parikshit M / Wittig, Hartmut

    Physical review letters

    2021  Volume 127, Issue 24, Page(s) 242003

    Abstract: We present the first study of baryon-baryon interactions in the continuum limit of lattice QCD, finding unexpectedly large lattice artifacts. Specifically, we determine the binding energy of the H dibaryon at a single quark-mass point. The calculation is ...

    Abstract We present the first study of baryon-baryon interactions in the continuum limit of lattice QCD, finding unexpectedly large lattice artifacts. Specifically, we determine the binding energy of the H dibaryon at a single quark-mass point. The calculation is performed at six values of the lattice spacing a, using O(a)-improved Wilson fermions at the SU(3)-symmetric point with m_{π}=m_{K}≈420  MeV. Energy levels are extracted by applying a variational method to correlation matrices of bilocal two-baryon interpolating operators computed using the distillation technique. Our analysis employs Lüscher's finite-volume quantization condition to determine the scattering phase shifts from the spectrum and vice versa, both above and below the two-baryon threshold. We perform global fits to the lattice spectra using parametrizations of the phase shift, supplemented by terms describing discretization effects, then extrapolate the lattice spacing to zero. The phase shift and the binding energy determined from it are found to be strongly affected by lattice artifacts. Our estimate of the binding energy in the continuum limit of three-flavor QCD is B_{H}^{SU(3)_{f}}=4.56±1.13_{stat}±0.63_{syst}  MeV.
    Language English
    Publishing date 2021-12-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.127.242003
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Post mortem brain temperature and its influence on quantitative MRI of the brain.

    Berger, Celine / Bauer, Melanie / Wittig, Holger / Scheurer, Eva / Lenz, Claudia

    Magma (New York, N.Y.)

    2021  Volume 35, Issue 3, Page(s) 375–387

    Abstract: Objective: MRI temperature sensitivity presents a major issue in in situ post mortem MRI (PMMRI), as the tissue temperatures differ from living persons due to passive cooling of the deceased. This study aims at computing brain temperature effects on the ...

    Abstract Objective: MRI temperature sensitivity presents a major issue in in situ post mortem MRI (PMMRI), as the tissue temperatures differ from living persons due to passive cooling of the deceased. This study aims at computing brain temperature effects on the MRI parameters to correct for temperature in PMMRI, laying the foundation for future projects on post mortem validation of in vivo MRI techniques.
    Materials and methods: Brain MRI parameters were assessed in vivo and in situ post mortem using a 3 T MRI scanner. Post mortem brain temperature was measured in situ transethmoidally. The temperature effect was computed by fitting a linear model to the MRI parameters and the corresponding brain temperature.
    Results: Linear positive temperature correlations were observed for T
    Discussion: The linear models will allow to correct for temperature in post mortem MRI. Comparing in vivo to post mortem conditions, the mean diffusivity, in contrast to T
    MeSH term(s) Autopsy ; Brain/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Temperature ; White Matter/diagnostic imaging
    Language English
    Publishing date 2021-10-29
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1160826-2
    ISSN 1352-8661 ; 0968-5243
    ISSN (online) 1352-8661
    ISSN 0968-5243
    DOI 10.1007/s10334-021-00971-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top