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  1. Article ; Online: Initiatives in South Africa to enhance the prescribing of generic proton pump inhibitors: findings and implications.

    Truter, Ilse / Shankar, Sushma / Bennie, Marion / Woerkom, Menno van / Godman, Brian

    Journal of comparative effectiveness research

    2015  Volume 4, Issue 2, Page(s) 123–131

    Abstract: Background: There have been multiple reforms in South Africa to conserve resources including policies to enhance generic use, such as compulsory generic substitution and copayments. However, there are concerns with the limited knowledge of their impact.! ...

    Abstract Background: There have been multiple reforms in South Africa to conserve resources including policies to enhance generic use, such as compulsory generic substitution and copayments. However, there are concerns with the limited knowledge of their impact.
    Objective: The objective was to determine utilization and expenditure of different proton pump inhibitors (PPIs).
    Methodology: A retrospective drug utilization study was conducted on a prescription database of a medical aid administrator in 2010.
    Results: The limited prescribing of single-sourced PPIs accounted for 21.5% of total prescriptions. The limited use of originators omeprazole and lansoprazole accounted for 1.8 and 1.4% of total prescriptions for the molecule, respectively. Generic prices accounted for 36-68% of the originator in 2010. Patients received on average 2.91 PPI prescriptions during the year.
    Conclusion: Policies to enhance prescribing of generics appear working. Opportunities exist to further lower generic prices given low prices in some European countries.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Drugs, Generic/economics ; Drugs, Generic/supply & distribution ; Female ; Humans ; Infant ; Infant, Newborn ; Lansoprazole/economics ; Lansoprazole/supply & distribution ; Male ; Middle Aged ; Omeprazole/economics ; Omeprazole/supply & distribution ; Practice Patterns, Physicians'/economics ; Practice Patterns, Physicians'/statistics & numerical data ; Private Sector/statistics & numerical data ; Proton Pump Inhibitors/economics ; Proton Pump Inhibitors/supply & distribution ; Retrospective Studies ; South Africa ; Young Adult
    Chemical Substances Drugs, Generic ; Proton Pump Inhibitors ; Lansoprazole (0K5C5T2QPG) ; Omeprazole (KG60484QX9)
    Language English
    Publishing date 2015-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2042-6313
    ISSN (online) 2042-6313
    DOI 10.2217/cer.14.70
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ongoing measures to enhance the efficiency of prescribing of proton pump inhibitors and statins in The Netherlands: influence and future implications.

    Woerkom, Menno van / Piepenbrink, Hans / Godman, Brian / Metz, Joost de / Campbell, Stephen / Bennie, Marion / Eimers, Marietta / Gustafsson, Lars L

    Journal of comparative effectiveness research

    2012  Volume 1, Issue 6, Page(s) 527–538

    Abstract: Background: Multiple reforms have recently been introduced in The Netherlands to improve prescribing efficiency. These include preference pricing policies for multiple sourced products, guidelines, and quality and efficiency targets, as well as regular ... ...

    Abstract Background: Multiple reforms have recently been introduced in The Netherlands to improve prescribing efficiency. These include preference pricing policies for multiple sourced products, guidelines, and quality and efficiency targets, as well as regular pharmacotherapy meetings.
    Objectives: Assess the influence of these multiple measures on prescribing efficiency.
    Methods: Retrospective observational study of all reimbursed prescriptions for proton pump inhibitors and statins between 2000 and 2010 using the Genees-en hulpmiddelen Informatie Project (Health Insurance) database. Utilization measured in defined daily doses. Narrative review of reforms.
    Results: Reimbursed expenditure for the proton pump inhibitors fell by 58% in 2010 versus 2000 despite a threefold increase in utilization, helped by increasing utilization of generic omeprazole at only 2% of the prepatent loss price in 2010. Similarly, reimbursed expenditure for the statins fell by 14% in 2010 versus 2000 despite a 3.8-fold increase in utilization. Again, this was helped by increasing utilization of generic simvastatin at only 2% of the prepatent loss originator price.
    Conclusion: Multiple supply and demand measures, including the preference pricing policy, appear to have appreciably enhanced proton pump inhibitor and statin prescribing efficiency, providing examples to other countries.
    MeSH term(s) Ambulatory Care/economics ; Drug Utilization Review ; Drugs, Generic/economics ; Drugs, Generic/supply & distribution ; Drugs, Generic/therapeutic use ; Health Expenditures ; Health Policy ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/economics ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/supply & distribution ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Netherlands ; Practice Patterns, Physicians'/standards ; Proton Pump Inhibitors/economics ; Proton Pump Inhibitors/supply & distribution ; Proton Pump Inhibitors/therapeutic use ; Reimbursement Mechanisms ; Retrospective Studies ; Stomach Diseases/drug therapy
    Chemical Substances Drugs, Generic ; Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Proton Pump Inhibitors
    Language English
    Publishing date 2012-11
    Publishing country England
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ISSN 2042-6313
    ISSN (online) 2042-6313
    DOI 10.2217/cer.12.52
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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