LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 1194

Search options

  1. Article ; Online: Pandemic Surge Models in the Time of Severe Acute Respiratory Syndrome Coronavirus 2: Wrong or Useful?

    Wong, John B

    Annals of internal medicine

    2020  Volume 173, Issue 5, Page(s) 396–398

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-16
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/M20-1956
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article: Esophageal resection for cancer in The University of Hong Kong, Queen Mary Hospital, Hong Kong, China (1982-2008).

    Wong, John

    Journal of thoracic disease

    2018  Volume 10, Issue Suppl 16, Page(s) S1843–S1844

    Abstract: Esophageal resection is a high-risk procedure. In the early 1980s, it carried a mortality of more than 20%. Through a concerted effort which include meticulous surgical technique, vigilant post-operative care, and a low threshold to correct respiratory ... ...

    Abstract Esophageal resection is a high-risk procedure. In the early 1980s, it carried a mortality of more than 20%. Through a concerted effort which include meticulous surgical technique, vigilant post-operative care, and a low threshold to correct respiratory problem, the mortality rate was reduced to almost 0%. Our single layer continuous anastomotic technique also dramatically reduced the anastomotic leakage rate.
    Language English
    Publishing date 2018-07-17
    Publishing country China
    Document type Editorial
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2018.01.84
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Book: Clinic handbook of gastroenterology

    Wong, John L. H.

    2002  

    Title variant Gastroenterology
    Author's details John L. H. Wong
    Language English
    Size XX, 249 S. : Ill., graph. Darst.
    Publisher BIOS
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT013482214
    ISBN 1-85996-053-7 ; 978-1-85996-053-0
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

  4. Article: Managing Suicide Ideation: A Targeted Approach.

    Wong, John Cm

    Annals of the Academy of Medicine, Singapore

    2019  Volume 48, Issue 9, Page(s) 279–281

    MeSH term(s) Anti-Anxiety Agents/therapeutic use ; Antidepressive Agents/therapeutic use ; Antipsychotic Agents/therapeutic use ; Commitment of Mentally Ill ; Electroconvulsive Therapy ; Health Literacy ; Humans ; Mental Health ; Patient Safety ; Psychotherapy ; Suicidal Ideation ; Suicide/prevention & control
    Chemical Substances Anti-Anxiety Agents ; Antidepressive Agents ; Antipsychotic Agents
    Language English
    Publishing date 2019-11-18
    Publishing country Singapore
    Document type Editorial
    ZDB-ID 604527-3
    ISSN 0304-4602
    ISSN 0304-4602
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: AI-Led Mental Health Support (Wysa) for Health Care Workers During COVID-19: Service Evaluation.

    Chang, Christel Lynne / Sinha, Chaitali / Roy, Madhavi / Wong, John Chee Meng

    JMIR formative research

    2024  Volume 8, Page(s) e51858

    Abstract: Background: The impact that the COVID-19 pandemic has had on health care workers' mental health, in particular, cannot be ignored. Not only did the pandemic exacerbate mental health challenges through elevated stress, anxiety, risk of infection, and ... ...

    Abstract Background: The impact that the COVID-19 pandemic has had on health care workers' mental health, in particular, cannot be ignored. Not only did the pandemic exacerbate mental health challenges through elevated stress, anxiety, risk of infection, and social isolation, but regulations to minimize infection additionally hindered the conduct of traditional in-person mental health care.
    Objective: This study explores the feasibility of using Wysa, an artificial intelligence-led mental health app, among health care workers.
    Methods: A national tertiary health care cluster in Singapore piloted the use of Wysa among its own health care workers to support the management of their mental well-being during the pandemic (July 2020-June 2022). The adoption of this digital mental health intervention circumvented the limitations of in-person contact and enabled large-scale access to evidence-based care. Rates and patterns of user engagement were evaluated.
    Results: Overall, the opportunity to use Wysa was well-received. Out of the 527 staff who were onboarded in the app, 80.1% (422/527) completed a minimum of 2 sessions. On average, users completed 10.9 sessions over 3.80 weeks. The interventions most used were for sleep and anxiety, with a strong repeat-use rate. In this sample, 46.2% (73/158) of health care workers reported symptoms of anxiety (Generalized Anxiety Disorder Assessment-7 [GAD-7]), and 15.2% (24/158) were likely to have symptoms of depression (Patient Health Questionnaire-2 [PHQ-2]).
    Conclusions: Based on the present findings, Wysa appears to strongly engage those with none to moderate symptoms of anxiety. This evaluation demonstrates the viability of implementing Wysa as a standard practice among this sample of health care workers, which may support the use of similar digital interventions across other communities.
    Language English
    Publishing date 2024-04-19
    Publishing country Canada
    Document type Journal Article
    ISSN 2561-326X
    ISSN (online) 2561-326X
    DOI 10.2196/51858
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Loneliness and Unmet Needs of Older Adults Living in Publicly Supported Housing.

    Sabo, Kathryn / Wong, John / Lopez, Ruth Palan

    Research in gerontological nursing

    2023  Volume 16, Issue 5, Page(s) 217–223

    Abstract: Guided by the RE-AIM framework, the current study sought to examine the relationship between perceived needs of older adults living in publicly supported housing and loneliness. Participants were males and females aged 70 to 83 years who identified as ... ...

    Abstract Guided by the RE-AIM framework, the current study sought to examine the relationship between perceived needs of older adults living in publicly supported housing and loneliness. Participants were males and females aged 70 to 83 years who identified as White or Chinese. Using the Camberwell Assessment of Need Short Appraisal Schedule and UCLA Loneliness Scale, the relationship between residents' needs and loneliness was assessed to guide the development of interventions. Results revealed residents self-reported 54% of their needs were met and rated their loneliness at a score of 36.5 (moderate level). Furthermore, there was a medium positive correlation between unmet needs and loneliness whereby high unmet needs were associated with higher loneliness scores. Findings suggest that these older adults living in publicly supported housing are vulnerable to the negative consequences of loneliness. Implementing equitable and inclusive interventions to address the impact of loneliness in the context of social determinants of health is warranted. [
    MeSH term(s) Male ; Female ; Humans ; Aged ; Loneliness ; Housing
    Language English
    Publishing date 2023-06-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2555277-6
    ISSN 1938-2464 ; 1940-4921
    ISSN (online) 1938-2464
    ISSN 1940-4921
    DOI 10.3928/19404921-20230606-02
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Genomic medicines: the coming waves?

    Xie, Wen / Chen, Baiping / Wong, John

    Nature reviews. Drug discovery

    2023  Volume 22, Issue 9, Page(s) 691–692

    Language English
    Publishing date 2023-06-12
    Publishing country England
    Document type News
    ZDB-ID 2062954-0
    ISSN 1474-1784 ; 1474-1776
    ISSN (online) 1474-1784
    ISSN 1474-1776
    DOI 10.1038/d41573-023-00098-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Dosimetric characterization of a rotating anode x-ray tube for FLASH radiotherapy research.

    Miles, Devin / Sforza, Daniel / Wong, John / Rezaee, Mohammad

    Medical physics

    2023  Volume 51, Issue 2, Page(s) 1474–1483

    Abstract: Purpose: Most current research toward ultra-high dose rate (FLASH) radiation is conducted with advanced proton and electron accelerators, which are of limited accessibility to basic laboratory research. An economical alternative to charged particle ... ...

    Abstract Purpose: Most current research toward ultra-high dose rate (FLASH) radiation is conducted with advanced proton and electron accelerators, which are of limited accessibility to basic laboratory research. An economical alternative to charged particle accelerators is to employ high-capacity rotating anode x-ray tubes to produce kilovoltage x-rays at FLASH dose rates at short source-to-surface distances (SSD). This work describes a comprehensive dosimetric evaluation of a rotating anode x-ray tube for potential application in laboratory FLASH study.
    Methods and materials: A commercially available high-capacity fluoroscopy x-ray tube with 75 kW input power was implemented as a potential FLASH irradiator. Radiochromic EBT3 film and thermoluminescent dosimeters (TLDs) were used to investigate the effects of SSD and field size on dose rates and depth-dose characteristics in kV-compatible solid water phantoms. Custom 3D printed accessories were developed to enable reproducible phantom setup at very short SSD. Open and collimated radiation fields were assessed.
    Results: Despite the lower x-ray energy and short SSD used, FLASH dose rates above 40 Gy/s were achieved for targets up to 10-mm depth in solid water. Maximum surface dose rates of 96 Gy/s were measured in the open field at 47 mm SSD. A non-uniform high-to-low dose gradient was observed in the planar dose distribution, characteristic of anode heel effects. With added collimation, beams up to 10-mm diameter with reasonable uniformity can be produced. Typical 80%-20% penumbra in the collimated x-ray FLASH beams were less than 1 mm at 5-mm depth in phantom. Ramp-up times at the maximum input current were less than 1 ms.
    Conclusion: Our dosimetric characterization demonstrates that rotating anode x-ray tube technology is capable of producing radiation beams in support of preclinical FLASH radiobiology research.
    MeSH term(s) X-Rays ; Radiometry/methods ; Radiotherapy Dosage ; Fluoroscopy ; Water
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2023-07-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 188780-4
    ISSN 2473-4209 ; 0094-2405
    ISSN (online) 2473-4209
    ISSN 0094-2405
    DOI 10.1002/mp.16609
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Predicting Suicide and its Prevention.

    Wong, John Cm

    Annals of the Academy of Medicine, Singapore

    2018  Volume 47, Issue 9, Page(s) 357–359

    MeSH term(s) Age Factors ; Humans ; International Cooperation ; Needs Assessment ; Prevalence ; Preventive Health Services/methods ; Preventive Health Services/standards ; Preventive Psychiatry ; Risk Factors ; Singapore/epidemiology ; Socioeconomic Factors ; Suicidal Ideation ; Suicide/prevention & control ; Suicide/psychology ; Suicide/statistics & numerical data
    Language English
    Publishing date 2018-10-14
    Publishing country Singapore
    Document type Editorial
    ZDB-ID 604527-3
    ISSN 0304-4602
    ISSN 0304-4602
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top