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  1. Article ; Online: Tyrosine kinase inhibitor-induced corneal ulcers.

    Kam, Ka Wai / Wong, Posey Po Yin / Young, Alvin L

    The Lancet. Oncology

    2019  Volume 20, Issue 1, Page(s) e65

    MeSH term(s) Adenocarcinoma of Lung/drug therapy ; Aged ; Antineoplastic Agents/adverse effects ; Corneal Ulcer/chemically induced ; Corneal Ulcer/pathology ; Corneal Ulcer/therapy ; Female ; Humans ; Lung Neoplasms/drug therapy ; Protein Kinase Inhibitors/adverse effects ; Withholding Treatment ; Wound Healing
    Chemical Substances Antineoplastic Agents ; Protein Kinase Inhibitors
    Language English
    Publishing date 2019-01-06
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(18)30520-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5696: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 460: Show issues

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  2. Article ; Online: Acute postoperative endophthalmitis after cataract operation: result of early vitrectomy within 24 hours of presentation.

    Iu, Lawrence Pui Leung / Chan, Ho Yan / Li, Gabriel Ka Hin / Ho, Mary / Mak, Andrew Chun Yue / Wong, Posey Po Yin / Kam, Ka Wai / Chen, Li Jia / Brelen, Marten / Young, Alvin Lerrmann

    Eye (London, England)

    2022  Volume 37, Issue 11, Page(s) 2344–2350

    Abstract: Objectives: To evaluate result of early pars plana vitrectomy (PPV) within 24 hours of presentation for acute postoperative endophthalmitis after cataract operation, and to determine factors that predict visual outcome.: Methods: Consecutive patients ...

    Abstract Objectives: To evaluate result of early pars plana vitrectomy (PPV) within 24 hours of presentation for acute postoperative endophthalmitis after cataract operation, and to determine factors that predict visual outcome.
    Methods: Consecutive patients who developed acute postoperative endophthalmitis within 6 weeks after cataract operation were reviewed. Patients were divided into two groups for analysis: (1) those receiving PPV within 24 hours of presentation (early PPV group), and (2) those receiving initial intravitreal antibiotics only without PPV within 24 hours of presentation (IVA group).
    Results: Out of 41,411 cataract operations, 22 eyes developed acute postoperative endophthalmitis. Presenting VA was hand-movement or worse in 72.7%. The most common organisms were Staphylococcus (40.9%), Streptococcus (13.6%) and Enterococcus (13.6%). 22.7% of eyes had good final VA ≥ 20/30 and 27.3% had poor final VA < 20/400. Early PPV group had significantly lower rate of requiring additional treatments to control infection (25% versus 80%, P = 0.030), higher rate of retinal detachment (25% versus 0%, P = 0.221) and similar final logMAR VA (1.08 ± 1.08 versus 0.80 ± 0.80, P = 0.489) compared to IVA. Multivariate linear regression analysis showed that worse final VA was significantly associated with Streptococcus (ß = 1.92, P = 0.007) and retinal detachment (ß = 1.72, P = 0.005) but not with early PPV (P = 0.225).
    Conclusion: Early PPV was superior to initial intravitreal antibiotics alone as it required fewer additional treatments to control infection. Visual outcome was similar between early PPV and initial intravitreal antibiotics alone despite high number of poor presenting VA of light-perception in early PPV group. Streptococcal infection and retinal detachment were major poor prognostic factors for vision.
    MeSH term(s) Humans ; Vitrectomy ; Retinal Detachment/surgery ; Postoperative Complications/surgery ; Endophthalmitis/therapy ; Anti-Bacterial Agents ; Cataract ; Retrospective Studies ; Treatment Outcome
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-12-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-022-02347-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 603: Show issues

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  3. Article ; Online: Delayed Diagnosis of Amblyopia in Children of Lower Socioeconomic Families: The Hong Kong Children Eye Study.

    Zhang, Xiu Juan / Wong, Posey Po-Yin / Wong, Emily S / Kam, Ka Wai / Yip, Benjamin Hon Kei / Zhang, Yuzhou / Zhang, Wei / Young, Alvin L / Chen, Li Jia / Ip, Patrick / Tham, Clement C / Pang, Chi Pui / Yam, Jason C

    Ophthalmic epidemiology

    2021  Volume 29, Issue 6, Page(s) 621–628

    Abstract: Aims: To determine the prevalence of amblyopia and the factors associated with delayed diagnosis among school-aged children in Hong Kong.: Methods: Completed comprehensive ophthalmoscopic examinations were conducted among 4.273 children aged 6-8 ... ...

    Abstract Aims: To determine the prevalence of amblyopia and the factors associated with delayed diagnosis among school-aged children in Hong Kong.
    Methods: Completed comprehensive ophthalmoscopic examinations were conducted among 4.273 children aged 6-8 years in the population-based Hong Kong Children Eye Study. New and previous diagnoses of amblyopia were identified. Socioeconomic status was surveyed through questionnaires.
    Results: According to criteria from the Multi-Ethnic Pediatric Eye Disease Study (MEPEDS), amblyopia was present in 43 out of 4,273 children (1.01%; 95% CI, 0.71-1.31). Among them, 33 (0.77%) were newly detected cases that were more likely from families living in Public Rental Housing or subdivided flats (OR, 4.22;
    Conclusion: These children with delayed diagnoses of amblyopia were more likely to come from lower socioeconomic backgrounds. Public education aimed at increasing awareness and utilization of child vision screening among such families is needed.
    MeSH term(s) Child ; Humans ; Amblyopia/diagnosis ; Amblyopia/epidemiology ; Hong Kong/epidemiology ; Delayed Diagnosis ; Visual Acuity ; Prevalence ; Social Class
    Language English
    Publishing date 2021-10-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1213070-9
    ISSN 1744-5086 ; 0928-6586
    ISSN (online) 1744-5086
    ISSN 0928-6586
    DOI 10.1080/09286586.2021.1986551
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4138: Show issues Location:
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