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  1. Article: Anterior and posterior medio-palatine bones.

    WOO, J K

    American journal of physical anthropology

    2008  Volume 6, Issue 2, Page(s) 209–223

    MeSH term(s) Humans ; Palate/anatomy & histology ; Palate, Hard
    Language English
    Publishing date 2008-08-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219376-0
    ISSN 1096-8644 ; 0002-9483
    ISSN (online) 1096-8644
    ISSN 0002-9483
    DOI 10.1002/ajpa.1330060211
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  2. Article: Blood grouping of four aboriginal tribes in Kweichow Province, China.

    WOO, J K

    American journal of physical anthropology

    2008  Volume 5, Issue 4, Page(s) 429–433

    MeSH term(s) Anthropology ; Blood Group Antigens ; Blood Grouping and Crossmatching ; China ; Humans ; Population Groups
    Chemical Substances Blood Group Antigens
    Language English
    Publishing date 2008-08-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219376-0
    ISSN 1096-8644 ; 0002-9483
    ISSN (online) 1096-8644
    ISSN 0002-9483
    DOI 10.1002/ajpa.1330050403
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  3. Article: Racial and sexual differences in the frontal curvature and its relation to metopism.

    WOO, J K

    American journal of physical anthropology

    2007  Volume 7, Issue 2, Page(s) 215–226

    MeSH term(s) Anthropology ; Humans ; Sexual Behavior
    Language English
    Publishing date 2007-11-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219376-0
    ISSN 1096-8644 ; 0002-9483
    ISSN (online) 1096-8644
    ISSN 0002-9483
    DOI 10.1002/ajpa.1330070205
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  4. Article: Torus palatinus.

    WOO, J K

    American journal of physical anthropology

    2004  Volume 8, Issue 1, Page(s) 81–111

    MeSH term(s) Continental Population Groups ; Exostoses ; Humans ; Palate
    Language English
    Publishing date 2004-09-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219376-0
    ISSN 1096-8644 ; 0002-9483
    ISSN (online) 1096-8644
    ISSN 0002-9483
    DOI 10.1002/ajpa.1330080114
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  5. Article: Ossification and growth of the human maxilla, premaxilla and palate bone.

    WOO, J K

    The Anatomical record

    2004  Volume 105, Issue 4, Page(s) 737–761

    MeSH term(s) Bone and Bones ; Humans ; Jaw ; Maxilla ; Osteogenesis ; Palate
    Language English
    Publishing date 2004-09-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 203685-x
    ISSN 0003-276X
    ISSN 0003-276X
    DOI 10.1002/ar.1091050408
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  6. Article ; Online: MRI of benign hyperplasia in the nasopharynx: is there an association with Epstein-Barr virus?

    Ai, Q-Y / King, A D / So, T Y / Lam, W K J / Mo, F K F / Tse, I O L / Woo, J K S / Chan, K C A

    Clinical radiology

    2020  Volume 75, Issue 9, Page(s) 711.e13–711.e18

    Abstract: Aim: To evaluate whether there is an association between persistently positive plasma Epstein-Barr virus (EBV) DNA and the presence and the change in benign hyperplasia.: Materials and methods: One hundred and seventeen participants with positive- ... ...

    Abstract Aim: To evaluate whether there is an association between persistently positive plasma Epstein-Barr virus (EBV) DNA and the presence and the change in benign hyperplasia.
    Materials and methods: One hundred and seventeen participants with positive-plasma EBV-DNA, but without NPC from previous nasopharyngeal carcinoma (NPC) screening, underwent follow-up magnetic resonance imaging (MRI) and plasma EBV-DNA after 2 years. Logistic regression was used to analyse associations between MRI (benign hyperplasia on the follow-up MRI and change from 2 years earlier), and plasma EBV-DNA, smoking, and age.
    Results: At follow-up, EBV-DNA positivity and smoking were independent parameters for the presence of benign hyperplasia (p=0.027 and 0.023 respectively). Compared with participants in whom EBV-DNA became negative (n=44/117 37.6%), those in whom EBV-DNA remained positive (n=73/117 62.4%) had a greater risk of benign hyperplasia developing (previous MRI normal), being stable or processing (52/73 71.2% versus 18/44 40.9%; p=0.001).
    Conclusion: These results suggest a potential link between benign hyperplasia on MRI and the EBV. As EBV contributes to NPC oncogenesis, future MRI research is warranted to determine if persistent benign hyperplasia is a risk marker for development of NPC.
    MeSH term(s) Adult ; Aged ; DNA, Viral/analysis ; Early Detection of Cancer/methods ; Epstein-Barr Virus Infections/diagnosis ; Epstein-Barr Virus Infections/virology ; Female ; Herpesvirus 4, Human/genetics ; Humans ; Hyperplasia/diagnosis ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Nasopharyngeal Neoplasms/diagnosis ; Nasopharyngeal Neoplasms/virology ; Nasopharynx/pathology ; Nasopharynx/virology ; Prospective Studies
    Chemical Substances DNA, Viral
    Language English
    Publishing date 2020-06-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 391227-9
    ISSN 1365-229X ; 0009-9260
    ISSN (online) 1365-229X
    ISSN 0009-9260
    DOI 10.1016/j.crad.2020.05.011
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  7. Article ; Online: Early Detection of Cancer: Evaluation of MR Imaging Grading Systems in Patients with Suspected Nasopharyngeal Carcinoma.

    King, A D / Woo, J K S / Ai, Q-Y / Mo, F K F / So, T Y / Lam, W K J / Tse, I O L / Vlantis, A C / Yip, K W N / Hui, E P / Ma, B B Y / Chiu, R W K / Chan, A T C / Lo, Y M D / Chan, K C A

    AJNR. American journal of neuroradiology

    2020  Volume 41, Issue 3, Page(s) 515–521

    Abstract: Background and purpose: We evaluated modifications to our contrast-enhanced MR imaging grading system for symptomatic patients with suspected nasopharyngeal carcinoma, aimed at improving discrimination of early-stage cancer and benign hyperplasia. We ... ...

    Abstract Background and purpose: We evaluated modifications to our contrast-enhanced MR imaging grading system for symptomatic patients with suspected nasopharyngeal carcinoma, aimed at improving discrimination of early-stage cancer and benign hyperplasia. We evaluated a second non-contrast-enhanced MR imaging grading system for asymptomatic patients from nasopharyngeal carcinoma plasma screening programs.
    Materials and methods: Dedicated nasopharyngeal MR imaging before (plain scan system) and after intravenous contrast administration (current and modified systems) was reviewed in patients from a nasopharyngeal carcinoma-endemic region, comprising 383 patients with suspected disease without nasopharyngeal carcinoma and 383 patients with nasopharyngeal carcinoma. The modified and plain scan systems refined primary tumor criteria, added a nodal assessment, and expanded the system from 4 to 5 grades. The overall combined sensitivity and specificity of the 3 systems were compared using the extended McNemar test (a χ
    Results: The current, modified, and plain scan MR imaging systems yielded sensitivities of 99.74%, 97.91%, and 97.65%, respectively, and specificities of 63.45%, 89.56% and 86.42%, respectively. The modified system yielded significantly better performance than the current ([Formula: see text] = 122) and plain scan ([Formula: see text] = 6.1) systems. The percentages of patients with nasopharyngeal carcinoma in grades 1-2, grade 3, and grades 4-5 for the modified and plain scan MR imaging systems were 0.42% and 0.44%; 6.31% and 6.96%; and 90.36% and 87.79%, respectively. No additional cancers were detected after contrast administration in cases of a plain scan graded 1-2.
    Conclusions: We propose a modified MR imaging grading system that improves diagnostic performance for nasopharyngeal carcinoma detection. Contrast was not valuable for low MR imaging grades, and the plain scan shows potential for use in screening programs.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Early Detection of Cancer/methods ; Female ; Humans ; Image Interpretation, Computer-Assisted/methods ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Nasopharyngeal Carcinoma/diagnostic imaging ; Nasopharyngeal Neoplasms/diagnostic imaging ; Retrospective Studies ; Sensitivity and Specificity ; Young Adult
    Language English
    Publishing date 2020-03-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603808-6
    ISSN 1936-959X ; 0195-6108
    ISSN (online) 1936-959X
    ISSN 0195-6108
    DOI 10.3174/ajnr.A6444
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  8. Article ; Online: Intracranial transthecal subarachnoid fat emboli and subarachnoid haemorrhage arising from a sacral fracture and dural tear.

    Woo, J K H / Malfair, D / Vertinsky, T / Heran, M K S / Graeb, D

    The British journal of radiology

    2010  Volume 83, Issue 985, Page(s) e18–21

    Abstract: We present the case of a 28-year-old man with an unusual aetiology of lipid-dense material in the subarachnoid space. CT of the head at presentation was normal. MRI of the spine revealed a defect in the dura at L5/S1, with avulsed left L5 and S1 nerve ... ...

    Abstract We present the case of a 28-year-old man with an unusual aetiology of lipid-dense material in the subarachnoid space. CT of the head at presentation was normal. MRI of the spine revealed a defect in the dura at L5/S1, with avulsed left L5 and S1 nerve roots. Haematoma and marrow fat were observed in close relation to the dural tear adjacent to the sacral fracture. Head CT and MRI subsequently demonstrated new lipid-dense material and haemorrhage in the subarachnoid space after sacral instrumentation, presumably owing to transthecal displacement of fatty marrow.
    MeSH term(s) Accidents, Traffic ; Adult ; Consciousness Disorders/etiology ; Dura Mater/injuries ; Embolism, Fat/diagnosis ; Embolism, Fat/etiology ; Humans ; Lumbar Vertebrae ; Magnetic Resonance Imaging ; Male ; Radiculopathy/etiology ; Sacrum/injuries ; Spinal Cord Injuries/complications ; Spinal Cord Injuries/surgery ; Spinal Fractures/complications ; Spinal Fractures/surgery ; Subarachnoid Hemorrhage/diagnosis ; Subarachnoid Hemorrhage/etiology ; Subarachnoid Space ; Tomography, X-Ray Computed
    Language English
    Publishing date 2010-02-05
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2982-8
    ISSN 1748-880X ; 0007-1285
    ISSN (online) 1748-880X
    ISSN 0007-1285
    DOI 10.1259/bjr/66268641
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  9. Article: Deafness in chronic myeloid leukemia.

    Chim, C S / Woo, J K

    Leukemia & lymphoma

    1997  Volume 26, Issue 1-2, Page(s) 209–210

    MeSH term(s) Adolescent ; Adult ; Hearing Loss, Bilateral/etiology ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/complications ; Male
    Language English
    Publishing date 1997-06
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 1042374-6
    ISSN 1029-2403 ; 1042-8194
    ISSN (online) 1029-2403
    ISSN 1042-8194
    DOI 10.3109/10428199709109179
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  10. Article ; Online: Essential role of insulin-like growth factor 2 in resistance to histone deacetylase inhibitors.

    Lee, S-C / Min, H-Y / Jung, H J / Park, K H / Hyun, S Y / Cho, J / Woo, J K / Kwon, S J / Lee, H-J / Johnson, F M / Lee, H-Y

    Oncogene

    2016  Volume 35, Issue 42, Page(s) 5515–5526

    Abstract: Histone deacetylase (HDAC) inhibitors (HDIs) are promising anticancer therapies and have been clinically used for the treatment of hematological malignancy. However, their efficacy in solid tumors is marginal and drug resistance hampers their further ... ...

    Abstract Histone deacetylase (HDAC) inhibitors (HDIs) are promising anticancer therapies and have been clinically used for the treatment of hematological malignancy. However, their efficacy in solid tumors is marginal and drug resistance hampers their further clinical utility. To develop novel strategies for the HDI-based anticancer therapeutics in non-small cell lung cancer (NSCLC), in the present study, we investigated the mechanisms underlying resistance to HDI treatment in NSCLC cells. We show the STAT3-mediated IGF2/IGF-1R signaling cascade as a key modulator for both acquired and primary HDI resistance. The treatment with HDI upregulated IGF2 transcription in NSCLC cells carrying intrinsic or acquired drug resistance via direct binding of STAT3 in IGF2 P3 and P4 promoters. Acetylated STAT3 emerged upon HDAC inhibition was protected from the proteasome-mediated degradation of STAT3 and functioned as a direct transcription factor for IGF2 expression. Genomic or pharmacological strategies targeting STAT3 diminished the HDI-induced IGF2 mRNA expression and overcame the resistance to HDI treatment in HDI-resistant NSCLC- or patient-derived tumor xenograft models. These findings provide new insights into the role of acetylated STAT3-mediated activation of IGF2 transcription in HDI resistance, suggesting IGF2 or STAT3 as novel targets to overcome HDI resistance in NSCLC.
    MeSH term(s) Acetylation ; Antineoplastic Agents/pharmacology ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/metabolism ; Cell Line, Tumor ; Drug Resistance, Neoplasm/genetics ; Gene Expression Regulation, Neoplastic/drug effects ; Histone Deacetylase Inhibitors/pharmacology ; Humans ; Hydroxamic Acids/pharmacology ; Insulin-Like Growth Factor II/genetics ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Promoter Regions, Genetic ; Protein Binding ; Receptor, IGF Type 1/metabolism ; STAT3 Transcription Factor/metabolism ; Transcription, Genetic
    Chemical Substances Antineoplastic Agents ; Histone Deacetylase Inhibitors ; Hydroxamic Acids ; STAT3 Transcription Factor ; vorinostat (58IFB293JI) ; Insulin-Like Growth Factor II (67763-97-7) ; Receptor, IGF Type 1 (EC 2.7.10.1)
    Language English
    Publishing date 2016-10-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 639046-8
    ISSN 1476-5594 ; 0950-9232
    ISSN (online) 1476-5594
    ISSN 0950-9232
    DOI 10.1038/onc.2016.92
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